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Aliases for ZNF567 Gene

Aliases for ZNF567 Gene

  • Zinc Finger Protein 567 2 3 5

External Ids for ZNF567 Gene

Previous GeneCards Identifiers for ZNF567 Gene

  • GC19P041872
  • GC19P037180
  • GC19P033648
  • GC19P036688

Summaries for ZNF567 Gene

GeneCards Summary for ZNF567 Gene

ZNF567 (Zinc Finger Protein 567) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF33B.

UniProtKB/Swiss-Prot for ZNF567 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF567 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF567 Gene

Genomics for ZNF567 Gene

GeneHancer (GH) Regulatory Elements for ZNF567 Gene

Promoters and enhancers for ZNF567 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I036685 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 589.9 -0.3 -273 2.6 PKNOX1 FOXA2 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 POLR2B ZNF766 ZNF567 LINC01534 ZNF571 ZNF345 ZNF383 ZNF850 ENSG00000267682 ZNF527 LOC728485 ZNF829
GH19I037370 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 236 +683.5 683476 1.9 HDGF PKNOX1 SMAD1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF213 ZNF527 ZNF567 ZNF383 ZNF345 ZFP30 ZNF571 HKR1 ZNF850 ZNF793 ZNF790
GH19I037466 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 222.6 +780.7 780651 4.4 FEZF1 DMAP1 IRF4 YY1 ZNF213 ZNF416 ZNF143 ZNF548 SP3 ZC3H11A ZNF570 ZNF569 ZNF567 ZNF345 ZNF383 ZNF527 ZNF850 ZNF571 ZNF585B HKR1
GH19I037593 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 216.1 +907.1 907137 2.2 PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 IRF4 YY1 SLC30A9 ZNF213 ZNF571 ZNF540 ZNF567 ZNF527 ZFP30 ZNF383 HKR1 ZNF345 ZNF585A ZNF607
GH19I037653 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 209.6 +967.7 967736 3 MLX ZFP64 FEZF1 DMAP1 YY1 ZNF213 ZNF416 ZNF143 ZNF548 SP3 ZFP30 ZNF527 ZNF567 ZNF383 ZNF345 ZNF571 ZNF790 HKR1 ZNF850 ZNF585A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF567 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF567 gene promoter:

Genomic Locations for ZNF567 Gene

Genomic Locations for ZNF567 Gene
chr19:36,687,564-36,727,701
(GRCh38/hg38)
Size:
40,138 bases
Orientation:
Plus strand
chr19:37,178,514-37,218,603
(GRCh37/hg19)

Genomic View for ZNF567 Gene

Genes around ZNF567 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF567 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF567 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF567 Gene

Proteins for ZNF567 Gene

  • Protein details for ZNF567 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N184-ZN567_HUMAN
    Recommended name:
    Zinc finger protein 567
    Protein Accession:
    Q8N184
    Secondary Accessions:
    • B3KX49
    • Q6N044

    Protein attributes for ZNF567 Gene

    Size:
    647 amino acids
    Molecular mass:
    75164 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF567 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF567 Gene

Post-translational modifications for ZNF567 Gene

  • Ubiquitination at posLast=5555
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ZNF567 Gene

Domains & Families for ZNF567 Gene

Gene Families for ZNF567 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF567 Gene

Suggested Antigen Peptide Sequences for ZNF567 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N184

UniProtKB/Swiss-Prot:

ZN567_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF567: view

Function for ZNF567 Gene

Molecular function for ZNF567 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF567 Gene

Gene Ontology (GO) - Molecular Function for ZNF567 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0005515 protein binding IPI 25416956
GO:0044212 transcription regulatory region DNA binding IBA --
genes like me logo Genes that share ontologies with ZNF567: view
genes like me logo Genes that share phenotypes with ZNF567: view

Animal Model Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF567 Gene

Localization for ZNF567 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF567 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF567 gene
Compartment Confidence
nucleus 5
cytosol 3
mitochondrion 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF567 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF567: view

Pathways & Interactions for ZNF567 Gene

SuperPathways for ZNF567 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF567: view

Pathways by source for ZNF567 Gene

2 Reactome pathways for ZNF567 Gene

Gene Ontology (GO) - Biological Process for ZNF567 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription by RNA polymerase II IBA --
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0045944 positive regulation of transcription by RNA polymerase II IBA --
genes like me logo Genes that share ontologies with ZNF567: view

No data available for SIGNOR curated interactions for ZNF567 Gene

Drugs & Compounds for ZNF567 Gene

No Compound Related Data Available

Transcripts for ZNF567 Gene

Unigene Clusters for ZNF567 Gene

Zinc finger protein 567:
Representative Sequences:

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF567 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5
SP1: -
SP2:
SP3:

Relevant External Links for ZNF567 Gene

GeneLoc Exon Structure for
ZNF567
ECgene alternative splicing isoforms for
ZNF567

Expression for ZNF567 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF567 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF567 Gene:

ZNF567

SOURCE GeneReport for Unigene cluster for ZNF567 Gene:

Hs.412517

Evidence on tissue expression from TISSUES for ZNF567 Gene

  • Liver(4.2)
  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF567: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF567 Gene

Orthologs for ZNF567 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF567 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF567 33 34
  • 99.73 (n)
cow
(Bos Taurus)
Mammalia ZNF567 33 34
  • 90.69 (n)
mouse
(Mus musculus)
Mammalia Zfp300 33 16
  • 61.76 (n)
Zfp719 34
  • 30 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Zfp300 33
  • 60.53 (n)
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 32 (a)
OneToMany
Species where no ortholog for ZNF567 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF567 Gene

ENSEMBL:
Gene Tree for ZNF567 (if available)
TreeFam:
Gene Tree for ZNF567 (if available)

Paralogs for ZNF567 Gene

(545) SIMAP similar genes for ZNF567 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF567: view

Variants for ZNF567 Gene

Sequence variations from dbSNP and Humsavar for ZNF567 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000058603 -- 36,681,365(+) G/A genic_upstream_transcript_variant, intron_variant
rs1000097529 -- 36,712,308(+) A/G intron_variant
rs1000257595 -- 36,706,191(+) A/G intron_variant
rs1000341319 -- 36,693,259(+) T/C/G genic_upstream_transcript_variant, intron_variant
rs1000369494 -- 36,675,042(+) T/A genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF567 Gene

Variant ID Type Subtype PubMed ID
dgv1042e212 CNV loss 25503493
dgv660e214 CNV loss 21293372
esv3389492 CNV insertion 20981092
esv34384 CNV loss 17911159
nsv1061250 CNV gain 25217958
nsv1064851 CNV loss 25217958
nsv469794 CNV loss 16826518
nsv470139 CNV loss 18288195
nsv817833 CNV loss 17921354
nsv833817 CNV loss 17160897

Variation tolerance for ZNF567 Gene

Residual Variation Intolerance Score: 15.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.04; 50.33% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF567 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF567

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF567 Gene

Disorders for ZNF567 Gene

Additional Disease Information for ZNF567

No disorders were found for ZNF567 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF567 Gene

Publications for ZNF567 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for ZNF567 Gene

Sources for ZNF567 Gene

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