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ZNF560 (Zinc Finger Protein 560) is a Protein Coding gene. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF778.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH19J009497 | Promoter/Enhancer | 1.1 | EPDnew Ensembl ENCODE | 606.6 | +8.4 | 8391 | 1.8 | CTCF CREM ZBTB33 ZBTB40 GABPB1 | ZNF560 ENSG00000267273 ENSG00000267612 piR-53431-325 LOC105372269 | |
GH19J009537 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE CraniofacialAtlas | 0.3 | -31.8 | -31823 | 3 | BRCA1 HNRNPL CREB1 GATAD2A ATF7 ZNF629 ZNF512 SIX5 NFKBIZ ZNF692 | ZNF426 ZNF426-DT ZNF266 ZNF699 FBXL12 ZNF317 ZNF558 CDC37 ZNF121 ZNF559 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003676 | nucleic acid binding | IEA | -- |
GO:0003677 | DNA binding | IEA | -- |
GO:0003700 | DNA-binding transcription factor activity | IBA | 21873635 |
GO:0043565 | sequence-specific DNA binding | IBA | 21873635 |
GO:0046872 | metal ion binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IBA | 21873635 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Gene Expression |
.48
|
|
2 | Herpes simplex virus 1 infection |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | |||||||||||||||||||||||
SP2: |
This gene was present in the common ancestor of mammals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ZNF560 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Zfp560 30 17 31 |
|
ManyToMany | |
Rat (Rattus norvegicus) |
Mammalia | Zfp560 30 |
|
||
Cow (Bos Taurus) |
Mammalia | -- 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs193920939 | Uncertain Significance: Malignant tumor of prostate | 9,467,851(-) | G/T | MISSENSE_VARIANT | |
VAR_035588 | A colorectal cancer sample | p.Gly186Glu | |||
rs10416098 | - | p.Tyr630Cys |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv3343658 | CNV | insertion | 20981092 |
esv995010 | CNV | deletion | 20482838 |
nsv1131397 | CNV | deletion | 24896259 |
No disorders were found for ZNF560 Gene.