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Aliases for ZNF547 Gene

Aliases for ZNF547 Gene

  • Zinc Finger Protein 547 2 3 3 5

External Ids for ZNF547 Gene

Previous GeneCards Identifiers for ZNF547 Gene

  • GC19P062568
  • GC19P062569
  • GC19P057875
  • GC19P054187
  • GC19P057365
  • GC19P057366
  • GC19P057367
  • GC19P057368
  • GC19P057372
  • GC19P057373
  • GC19P057374
  • GC19P057375

Summaries for ZNF547 Gene

GeneCards Summary for ZNF547 Gene

ZNF547 (Zinc Finger Protein 547) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF17.

UniProtKB/Swiss-Prot for ZNF547 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF547 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF547 Gene

Genomics for ZNF547 Gene

GeneHancer (GH) Regulatory Elements for ZNF547 Gene

Promoters and enhancers for ZNF547 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J057361 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 650.7 -0.4 -433 3.2 HDGF PKNOX1 FOXA2 ARID4B SIN3A DMAP1 ZNF2 IRF4 YY1 E2F8 ENSG00000268133 TRAPPC2B ZNF547 ZNF548 ZNF304 ZNF264 LOC105372483 ZFP28 ZNF471 LOC100132009
GH19J057364 Promoter 0.5 EPDnew 650.7 +1.3 1310 0.1 ENSG00000268133 TRAPPC2B ZNF547 ZNF548 GC19M057341
GH19J057371 Promoter 0.5 EPDnew 650.4 +8.5 8456 0.1 ZNF547 ENSG00000268133 ZNF548 GC19M057341
GH19J056403 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 18.7 -959.3 -959286 2 HDGF ARNT ARID4B SIN3A DMAP1 YY1 POLR2B ZNF766 ZNF416 ZNF207 ZNF582 ZNF582-AS1 ZFP28 ZNF470 ZNF471 FIZ1 ZNF264 ZNF460-AS1 ENSG00000269696 ZNF542P
GH19J057278 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 11.6 -82.0 -81959 6.7 ZFP64 FEZF1 DMAP1 YY1 E2F8 ZNF143 SP3 NFYC ZC3H11A MEF2D ZNF460 ZNF460-AS1 ZNF264 ZNF805 ZNF134 ZNF543 ZNF549 ZNF17 ZNF329 ZNF256
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF547 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF547 gene promoter:
  • RORalpha2
  • En-1
  • RFX1
  • MRF-2
  • Msx-1
  • Nkx3-1 v4
  • Nkx3-1 v3
  • Nkx3-1 v2
  • Nkx3-1 v1
  • Nkx3-1

Genomic Locations for ZNF547 Gene

Genomic Locations for ZNF547 Gene
chr19:57,363,435-57,379,565
(GRCh38/hg38)
Size:
16,131 bases
Orientation:
Plus strand
chr19:57,874,845-57,890,933
(GRCh37/hg19)
Size:
16,089 bases
Orientation:
Plus strand

Genomic View for ZNF547 Gene

Genes around ZNF547 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF547 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF547 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF547 Gene

Proteins for ZNF547 Gene

  • Protein details for ZNF547 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IVP9-ZN547_HUMAN
    Recommended name:
    Zinc finger protein 547
    Protein Accession:
    Q8IVP9
    Secondary Accessions:
    • A8K5Z9
    • Q96NC4

    Protein attributes for ZNF547 Gene

    Size:
    402 amino acids
    Molecular mass:
    45956 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF547 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF547 Gene

Post-translational modifications for ZNF547 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF547 Gene

No data available for DME Specific Peptides for ZNF547 Gene

Domains & Families for ZNF547 Gene

Gene Families for ZNF547 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF547 Gene

Suggested Antigen Peptide Sequences for ZNF547 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IVP9

UniProtKB/Swiss-Prot:

ZN547_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF547: view

Function for ZNF547 Gene

Molecular function for ZNF547 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF547 Gene

Gene Ontology (GO) - Molecular Function for ZNF547 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISA --
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF547: view
genes like me logo Genes that share phenotypes with ZNF547: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF547 Gene

Localization for ZNF547 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF547 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF547 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF547 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF547: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF547 Gene

Pathways & Interactions for ZNF547 Gene

SuperPathways for ZNF547 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF547: view

Pathways by source for ZNF547 Gene

2 Reactome pathways for ZNF547 Gene

Interacting Proteins for ZNF547 Gene

Gene Ontology (GO) - Biological Process for ZNF547 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZNF547: view

No data available for SIGNOR curated interactions for ZNF547 Gene

Drugs & Compounds for ZNF547 Gene

No Compound Related Data Available

Transcripts for ZNF547 Gene

mRNA/cDNA for ZNF547 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF547 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c
SP1: -
SP2: - -
SP3:
SP4:

Relevant External Links for ZNF547 Gene

GeneLoc Exon Structure for
ZNF547
ECgene alternative splicing isoforms for
ZNF547

Expression for ZNF547 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF547 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF547 Gene:

ZNF547

Evidence on tissue expression from TISSUES for ZNF547 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ZNF547: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF547 Gene

Orthologs for ZNF547 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF547 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF547 34 33
  • 99.42 (n)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF547 34
  • 45 (a)
OneToOne
Species where no ortholog for ZNF547 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF547 Gene

ENSEMBL:
Gene Tree for ZNF547 (if available)
TreeFam:
Gene Tree for ZNF547 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF547: view image

Paralogs for ZNF547 Gene

(544) SIMAP similar genes for ZNF547 Gene using alignment to 4 proteins:

  • ZN547_HUMAN
  • M0QX63_HUMAN
  • M0QYW2_HUMAN
  • M0QZZ8_HUMAN
genes like me logo Genes that share paralogs with ZNF547: view

Variants for ZNF547 Gene

Sequence variations from dbSNP and Humsavar for ZNF547 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000249014 -- 57,366,030(+) A/C intron_variant
rs1000614090 -- 57,370,850(+) C/T intron_variant
rs1000630374 -- 57,376,728(+) A/T intron_variant
rs1000872006 -- 57,362,631(+) A/T upstream_transcript_variant
rs1001179812 -- 57,376,652(+) T/C/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF547 Gene

Variant ID Type Subtype PubMed ID
nsv960881 CNV duplication 23825009

Variation tolerance for ZNF547 Gene

Residual Variation Intolerance Score: 45% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.29; 25.73% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF547 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF547

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF547 Gene

Disorders for ZNF547 Gene

Additional Disease Information for ZNF547

No disorders were found for ZNF547 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF547 Gene

Publications for ZNF547 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for ZNF547 Gene

Sources for ZNF547 Gene

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