Aliases for ZNF547 Gene

Aliases for ZNF547 Gene

  • Zinc Finger Protein 547 2 3 4 5
  • Trafficking Protein Particle Complex Subunit 2B 3
  • MBP-1-Interacting Protein 2A 3
  • TRAPPC2.19 3
  • TRAPPC2P1 3
  • TRAPPC2B 3
  • FLJ31100 2
  • MIP-2A 3
  • SEDLP1 3
  • ZNF547 5

External Ids for ZNF547 Gene

Previous GeneCards Identifiers for ZNF547 Gene

  • GC19P062568
  • GC19P062569
  • GC19P057875
  • GC19P054187
  • GC19P057365
  • GC19P057366
  • GC19P057378
  • GC19P057379
  • GC19P057381
  • GC19P057383
  • GC19P057367
  • GC19P057368
  • GC19P057372
  • GC19P057373
  • GC19P057374
  • GC19P057375
  • GC19P057376
  • GC19P057377

Summaries for ZNF547 Gene

GeneCards Summary for ZNF547 Gene

ZNF547 (Zinc Finger Protein 547) is a Protein Coding gene. Diseases associated with ZNF547 include Spinal Muscular Atrophy, Type Iii and Epidermodysplasia Verruciformis 1. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF17.

UniProtKB/Swiss-Prot Summary for ZNF547 Gene

Additional gene information for ZNF547 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF547 Gene

Genomics for ZNF547 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF547 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF547 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF547

Top Transcription factor binding sites by QIAGEN in the ZNF547 gene promoter:
  • En-1
  • MRF-2
  • Msx-1
  • Nkx3-1
  • Nkx3-1 v1
  • Nkx3-1 v2
  • Nkx3-1 v3
  • Nkx3-1 v4
  • RFX1
  • RORalpha2

Genomic Locations for ZNF547 Gene

Genomic Locations for ZNF547 Gene
chr19:57,363,477-57,379,565
(GRCh38/hg38)
Size:
16,089 bases
Orientation:
Plus strand
chr19:57,874,845-57,890,933
(GRCh37/hg19)
Size:
16,089 bases
Orientation:
Plus strand

Genomic View for ZNF547 Gene

Genes around ZNF547 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF547 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF547 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF547 Gene

Proteins for ZNF547 Gene

  • Protein details for ZNF547 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IVP9-ZN547_HUMAN
    Recommended name:
    Zinc finger protein 547
    Protein Accession:
    Q8IVP9
    Secondary Accessions:
    • A8K5Z9
    • Q96NC4

    Protein attributes for ZNF547 Gene

    Size:
    402 amino acids
    Molecular mass:
    45956 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF547 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF547 Gene

Post-translational modifications for ZNF547 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF547 Gene

No data available for DME Specific Peptides for ZNF547 Gene

Domains & Families for ZNF547 Gene

Gene Families for ZNF547 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF547 Gene

InterPro:
Blocks:
  • KRAB box
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF547 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 547 (ZN547_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8IVP9

UniProtKB/Swiss-Prot:

ZN547_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF547: view

Function for ZNF547 Gene

Molecular function for ZNF547 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF547 Gene

Gene Ontology (GO) - Molecular Function for ZNF547 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF547: view
genes like me logo Genes that share phenotypes with ZNF547: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF547

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF547 Gene

Localization for ZNF547 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF547 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF547 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF547 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF547: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF547 Gene

Pathways & Interactions for ZNF547 Gene

genes like me logo Genes that share pathways with ZNF547: view

Pathways by source for ZNF547 Gene

2 Reactome pathways for ZNF547 Gene
1 KEGG pathway for ZNF547 Gene

Gene Ontology (GO) - Biological Process for ZNF547 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF547: view

No data available for SIGNOR curated interactions for ZNF547 Gene

Drugs & Compounds for ZNF547 Gene

No Compound Related Data Available

Transcripts for ZNF547 Gene

mRNA/cDNA for ZNF547 Gene

1 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF547

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF547 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c
SP1: -
SP2: - -
SP3:
SP4:

Relevant External Links for ZNF547 Gene

GeneLoc Exon Structure for
ZNF547

Expression for ZNF547 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF547 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF547

Evidence on tissue expression from TISSUES for ZNF547 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ZNF547: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF547 Gene

Orthologs for ZNF547 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF547 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ZNF547 30 31
  • 99.42 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia ZNF547 31
  • 45 (a)
OneToOne
Species where no ortholog for ZNF547 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ZNF547 Gene

ENSEMBL:
Gene Tree for ZNF547 (if available)
TreeFam:
Gene Tree for ZNF547 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF547: view image

Paralogs for ZNF547 Gene

(544) SIMAP similar genes for ZNF547 Gene using alignment to 4 proteins:

  • ZN547_HUMAN
  • M0QX63_HUMAN
  • M0QYW2_HUMAN
  • M0QZZ8_HUMAN
genes like me logo Genes that share paralogs with ZNF547: view

Variants for ZNF547 Gene

Additional dbSNP identifiers (rs#s) for ZNF547 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF547 Gene

Variant ID Type Subtype PubMed ID
nsv960881 CNV duplication 23825009

Variation tolerance for ZNF547 Gene

Residual Variation Intolerance Score: 45% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.29; 25.73% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF547 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF547

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF547 Gene

Disorders for ZNF547 Gene

MalaCards: The human disease database

(2) MalaCards diseases for ZNF547 Gene - From: DISEASES

Disorder Aliases PubMed IDs
spinal muscular atrophy, type iii
  • sma3
epidermodysplasia verruciformis 1
  • epidermodysplasia verruciformis, susceptibility to, 1
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with ZNF547: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF547 Gene

Publications for ZNF547 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  3. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for ZNF547 Gene

Sources for ZNF547 Gene