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Aliases for ZNF530 Gene

Aliases for ZNF530 Gene

  • Zinc Finger Protein 530 2 3 5
  • KIAA1508 4

External Ids for ZNF530 Gene

Previous GeneCards Identifiers for ZNF530 Gene

  • GC19P062803
  • GC19P058111
  • GC19P054423

Summaries for ZNF530 Gene

GeneCards Summary for ZNF530 Gene

ZNF530 (Zinc Finger Protein 530) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF551.

UniProtKB/Swiss-Prot for ZNF530 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF530 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF530 Gene

Genomics for ZNF530 Gene

GeneHancer (GH) Regulatory Elements for ZNF530 Gene

Promoters and enhancers for ZNF530 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I057599 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 560.8 +0.2 152 1.5 PKNOX1 SMAD1 ARID4B SIN3A DMAP1 YY1 E2F8 ZNF207 ZNF143 KLF13 ZNF530 ZNF606 ZNF549 ZNF135 ZNF417 ZNF132 ZNF418 ZNF446 ZNF17 LOC105372482
GH19I058517 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 13.3 +919.8 919823 4.9 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF416 ZNF143 ZBTB45 PIR40518 ZNF324B TRIM28 ZNF446 ZNF134 ZNF417 ZSCAN22 ZNF549 ZNF274
GH19I058553 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 12.3 +957.2 957228 7.2 CLOCK FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 CHMP2A UBE2M TRIM28 ZNF417 ZNF134 ZNF606 ZNF274 MZF1 LOC100128398 ERVK3-1
GH19I057681 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 13.5 +82.3 82261 1.6 PKNOX1 ARID4B SIN3A DMAP1 YY1 POLR2B E2F8 ZNF416 ZNF207 ZNF143 ZNF551 ENSG00000269026 GC19P057683 ZNF17 ZNF549 ZNF304 ZNF134 ZNF773 ZNF446 ZNF211
GH19I057583 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 13.7 -15.9 -15854 1.5 ARID4B ZNF76 SIN3A KLF5 ZBTB40 YY1 ETS1 ZEB1 ZNF335 GLIS2 ZIK1 ZNF549 ZNF446 ZNF17 LOC100128398 ZNF324B MZF1 ZSCAN22 ZNF606 ZNF544
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF530 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF530 gene promoter:

Genomic Locations for ZNF530 Gene

Genomic Locations for ZNF530 Gene
chr19:57,599,885-57,612,722
(GRCh38/hg38)
Size:
12,838 bases
Orientation:
Plus strand
chr19:58,111,253-58,124,090
(GRCh37/hg19)

Genomic View for ZNF530 Gene

Genes around ZNF530 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF530 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF530 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF530 Gene

Proteins for ZNF530 Gene

  • Protein details for ZNF530 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P9A1-ZN530_HUMAN
    Recommended name:
    Zinc finger protein 530
    Protein Accession:
    Q6P9A1
    Secondary Accessions:
    • O43340
    • Q9P220

    Protein attributes for ZNF530 Gene

    Size:
    599 amino acids
    Molecular mass:
    68837 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC24609.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAA96032.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305};

neXtProt entry for ZNF530 Gene

Post-translational modifications for ZNF530 Gene

No Post-translational modifications

Other Protein References for ZNF530 Gene

No data available for DME Specific Peptides for ZNF530 Gene

Domains & Families for ZNF530 Gene

Gene Families for ZNF530 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for ZNF530 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6P9A1

UniProtKB/Swiss-Prot:

ZN530_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF530: view

Function for ZNF530 Gene

Molecular function for ZNF530 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF530 Gene

Gene Ontology (GO) - Molecular Function for ZNF530 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF530: view
genes like me logo Genes that share phenotypes with ZNF530: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF530 Gene

Localization for ZNF530 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF530 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF530 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF530 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF530: view

Pathways & Interactions for ZNF530 Gene

SuperPathways for ZNF530 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF530: view

Pathways by source for ZNF530 Gene

2 Reactome pathways for ZNF530 Gene

Interacting Proteins for ZNF530 Gene

Gene Ontology (GO) - Biological Process for ZNF530 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF530: view

No data available for SIGNOR curated interactions for ZNF530 Gene

Drugs & Compounds for ZNF530 Gene

No Compound Related Data Available

Transcripts for ZNF530 Gene

Unigene Clusters for ZNF530 Gene

Zinc finger protein 530:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF530 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b
SP1:
SP2: - - - -
SP3: -
SP4: -
SP5:

Relevant External Links for ZNF530 Gene

GeneLoc Exon Structure for
ZNF530
ECgene alternative splicing isoforms for
ZNF530

Expression for ZNF530 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF530 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF530 Gene:

ZNF530

SOURCE GeneReport for Unigene cluster for ZNF530 Gene:

Hs.97111

Evidence on tissue expression from TISSUES for ZNF530 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ZNF530: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF530 Gene

Orthologs for ZNF530 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF530 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF530 33 34
  • 99.33 (n)
cow
(Bos Taurus)
Mammalia ZNF154 34
  • 40 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 34
  • 39 (a)
ManyToMany
Species where no ortholog for ZNF530 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF530 Gene

ENSEMBL:
Gene Tree for ZNF530 (if available)
TreeFam:
Gene Tree for ZNF530 (if available)

Paralogs for ZNF530 Gene

(480) SIMAP similar genes for ZNF530 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF530: view

Variants for ZNF530 Gene

Sequence variations from dbSNP and Humsavar for ZNF530 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000010023 -- 57,612,192(+) T/C genic_downstream_transcript_variant, intron_variant
rs1000283954 -- 57,603,564(+) G/A intron_variant
rs1000372417 -- 57,609,423(+) G/A 3_prime_UTR_variant, downstream_transcript_variant, genic_downstream_transcript_variant, intron_variant
rs1000435571 -- 57,609,679(+) G/A 3_prime_UTR_variant, genic_downstream_transcript_variant, intron_variant
rs1000613142 -- 57,603,227(+) C/G/T intron_variant

Variation tolerance for ZNF530 Gene

Residual Variation Intolerance Score: 93.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.68; 57.19% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF530 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF530

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF530 Gene

Disorders for ZNF530 Gene

Additional Disease Information for ZNF530

No disorders were found for ZNF530 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF530 Gene

Publications for ZNF530 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10819331) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 2 3 4 58
  2. Exome sequencing supports a de novo mutational paradigm for schizophrenia. (PMID: 21822266) Xu B … Karayiorgou M (Nature genetics 2011) 3 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for ZNF530 Gene

Sources for ZNF530 Gene

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