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Aliases for ZNF529 Gene

Aliases for ZNF529 Gene

  • Zinc Finger Protein 529 2 3 5
  • KIAA1615 4

External Ids for ZNF529 Gene

Previous GeneCards Identifiers for ZNF529 Gene

  • GC19M041727
  • GC19M037034
  • GC19M033502
  • GC19M037157
  • GC19M036677
  • GC19M036709
  • GC19M036893
  • GC19M036911
  • GC19M037448
  • GC19M037788
  • GC19M038086

Summaries for ZNF529 Gene

GeneCards Summary for ZNF529 Gene

ZNF529 (Zinc Finger Protein 529) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF784.

UniProtKB/Swiss-Prot for ZNF529 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF529 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF529 Gene

Genomics for ZNF529 Gene

GeneHancer (GH) Regulatory Elements for ZNF529 Gene

Promoters and enhancers for ZNF529 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I036572 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 611.6 +31.9 31903 3 CLOCK ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF416 ZNF143 ZNF529 ZNF529-AS1 ZNF790-AS1 ZNF567 ZFP82 ZNF527 ZNF585A LINC01534 ZNF793 ZNF383
GH19I036604 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 573.6 +0.1 96 2.4 HDGF PKNOX1 ARID4B FEZF1 DMAP1 ZNF2 ZNF213 ZNF416 ZNF143 ZNF548 ZNF529 ZNF382 ZNF383 ZNF567 ZNF345 ZNF850 HKR1 ZNF527 ZNF585B ZNF571
GH19I036915 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE 118 -311.1 -311084 2.2 PKNOX1 ARID4B SIN3A ZNF2 YY1 ZNF302 ZNF416 ZNF143 ZNF548 SP3 ZNF568 ZNF829 GC19M038851 ZNF527 ZNF567 ZNF345 ZNF383 ZFP30 ZNF571 ZNF850
GH19I035897 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 93.4 +701.4 701353 13 CLOCK FEZF1 IRF4 YY1 ZNF213 ZNF143 ZNF548 SP3 NFYC ZFP41 NFKBID TYROBP HCST ENSG00000280194 ZNF567 ZNF566 ZNF790 ZNF529 TMEM147-AS1 ZNF260
GH19I035710 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 75.6 +890.2 890218 10 ZFP64 DMAP1 IRF4 YY1 ZNF213 ZNF143 ZNF548 ZNF263 SP3 ZFP41 KMT2B ZBTB32 PIR52641 ZNF529 ZNF567 ZNF461 TMEM147-AS1 ZNF599 LINC01534 ZFP82
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF529 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF529 gene promoter:

Genomic Locations for ZNF529 Gene

Genomic Locations for ZNF529 Gene
chr19:36,534,518-36,605,411
(GRCh38/hg38)
Size:
70,894 bases
Orientation:
Minus strand
chr19:37,025,676-37,096,178
(GRCh37/hg19)

Genomic View for ZNF529 Gene

Genes around ZNF529 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF529 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF529 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF529 Gene

Proteins for ZNF529 Gene

  • Protein details for ZNF529 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P280-ZN529_HUMAN
    Recommended name:
    Zinc finger protein 529
    Protein Accession:
    Q6P280
    Secondary Accessions:
    • K7EKE1
    • Q9H731
    • Q9HCF7

    Protein attributes for ZNF529 Gene

    Size:
    563 amino acids
    Molecular mass:
    65865 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH64690.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB15068.1; Type=Frameshift; Positions=78; Evidence={ECO:0000305};

neXtProt entry for ZNF529 Gene

Post-translational modifications for ZNF529 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZNF529 Gene

Domains & Families for ZNF529 Gene

Gene Families for ZNF529 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF529 Gene

Suggested Antigen Peptide Sequences for ZNF529 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6P280

UniProtKB/Swiss-Prot:

ZN529_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF529: view

Function for ZNF529 Gene

Molecular function for ZNF529 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF529 Gene

Gene Ontology (GO) - Molecular Function for ZNF529 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF529: view
genes like me logo Genes that share phenotypes with ZNF529: view

miRNA for ZNF529 Gene

miRTarBase miRNAs that target ZNF529

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF529 Gene

Localization for ZNF529 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF529 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF529 gene
Compartment Confidence
nucleus 5
cytosol 3
golgi apparatus 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF529 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF529: view

Pathways & Interactions for ZNF529 Gene

SuperPathways for ZNF529 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF529: view

Pathways by source for ZNF529 Gene

2 Reactome pathways for ZNF529 Gene

Gene Ontology (GO) - Biological Process for ZNF529 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF529: view

No data available for SIGNOR curated interactions for ZNF529 Gene

Drugs & Compounds for ZNF529 Gene

No Compound Related Data Available

Transcripts for ZNF529 Gene

Unigene Clusters for ZNF529 Gene

Zinc finger protein 529:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF529 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c
SP1: - -
SP2: -
SP3:
SP4: - - -

Relevant External Links for ZNF529 Gene

GeneLoc Exon Structure for
ZNF529
ECgene alternative splicing isoforms for
ZNF529

Expression for ZNF529 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF529 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF529 Gene:

ZNF529

SOURCE GeneReport for Unigene cluster for ZNF529 Gene:

Hs.654960

Evidence on tissue expression from TISSUES for ZNF529 Gene

  • Nervous system(4.5)
  • Intestine(4.1)
genes like me logo Genes that share expression patterns with ZNF529: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF529 Gene

Orthologs for ZNF529 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF529 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF529 33 34
  • 99.29 (n)
cow
(Bos Taurus)
Mammalia ZNF529 33
  • 86.58 (n)
dog
(Canis familiaris)
Mammalia ZNF529 34
  • 80 (a)
OneToOne
Species where no ortholog for ZNF529 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF529 Gene

ENSEMBL:
Gene Tree for ZNF529 (if available)
TreeFam:
Gene Tree for ZNF529 (if available)

Paralogs for ZNF529 Gene

Paralogs for ZNF529 Gene

(531) SIMAP similar genes for ZNF529 Gene using alignment to 6 proteins:

Pseudogenes.org Pseudogenes for ZNF529 Gene

genes like me logo Genes that share paralogs with ZNF529: view

Variants for ZNF529 Gene

Sequence variations from dbSNP and Humsavar for ZNF529 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000027576 -- 36,583,681(-) AAAAAAA/AAAAAA/AAAAAAAA genic_upstream_transcript_variant, intron_variant
rs1000059156 -- 36,595,215(-) A/C/G genic_upstream_transcript_variant, intron_variant
rs1000156644 -- 36,589,737(-) G/C genic_upstream_transcript_variant, intron_variant
rs1000165260 -- 36,602,441(-) T/A/C genic_upstream_transcript_variant, intron_variant
rs1000184058 -- 36,555,034(-) T/C genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF529 Gene

Variant ID Type Subtype PubMed ID
nsv833817 CNV loss 17160897
nsv138053 CNV deletion 16902084
nsv1146826 CNV deletion 26484159
nsv1071931 CNV deletion 25765185
nsv1064851 CNV loss 25217958
nsv1056134 CNV loss 25217958
esv3644264 CNV loss 21293372
esv3644261 CNV loss 21293372
esv3556341 CNV deletion 23714750
esv2718504 CNV deletion 23290073
esv2664896 CNV deletion 23128226
esv2570514 CNV deletion 19546169
esv2205269 CNV deletion 18987734
esv1768990 CNV deletion 17803354
esv1008911 CNV deletion 20482838
dgv1778n106 CNV deletion 24896259

Variation tolerance for ZNF529 Gene

Residual Variation Intolerance Score: 46.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.13; 22.83% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF529 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF529

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF529 Gene

Disorders for ZNF529 Gene

Additional Disease Information for ZNF529

No disorders were found for ZNF529 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF529 Gene

Publications for ZNF529 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 2 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  5. SR protein kinases promote splicing of nonconsensus introns. (PMID: 26167880) Lipp JJ … Guthrie C (Nature structural & molecular biology 2015) 3 58

Products for ZNF529 Gene

Sources for ZNF529 Gene

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