Aliases for ZNF529 Gene

Aliases for ZNF529 Gene

  • Zinc Finger Protein 529 2 3 4 5
  • KIAA1615 2 4
  • ZNF529 5

External Ids for ZNF529 Gene

Previous GeneCards Identifiers for ZNF529 Gene

  • GC19M041727
  • GC19M037034
  • GC19M033502
  • GC19M037157
  • GC19M036677
  • GC19M036709
  • GC19M040547
  • GC19M040976
  • GC19M041397
  • GC19M042395
  • GC19M036893
  • GC19M036911
  • GC19M037448
  • GC19M037788
  • GC19M038086
  • GC19M038374
  • GC19M038667
  • GC19M040157

Summaries for ZNF529 Gene

GeneCards Summary for ZNF529 Gene

ZNF529 (Zinc Finger Protein 529) is a Protein Coding gene. Diseases associated with ZNF529 include N Syndrome. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF404.

UniProtKB/Swiss-Prot Summary for ZNF529 Gene

Additional gene information for ZNF529 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF529 Gene

Genomics for ZNF529 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF529 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF529 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF529

Top Transcription factor binding sites by QIAGEN in the ZNF529 gene promoter:
  • AhR
  • aMEF-2
  • Arnt
  • Egr-2
  • Egr-3
  • FAC1
  • MEF-2
  • MEF-2A
  • Nkx2-5

Genomic Locations for ZNF529 Gene

Genomic Locations for ZNF529 Gene
70,921 bases
Minus strand
70,503 bases
Minus strand

Genomic View for ZNF529 Gene

Genes around ZNF529 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF529 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF529 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF529 Gene

Proteins for ZNF529 Gene

  • Protein details for ZNF529 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 529
    Protein Accession:
    Secondary Accessions:
    • K7EKE1
    • Q9H731
    • Q9HCF7

    Protein attributes for ZNF529 Gene

    563 amino acids
    Molecular mass:
    65865 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH64690.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAB15068.1; Type=Frameshift; Evidence={ECO:0000305};

neXtProt entry for ZNF529 Gene

Post-translational modifications for ZNF529 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF529 Gene

Domains & Families for ZNF529 Gene

Gene Families for ZNF529 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF529 Gene

  • KRAB box

Suggested Antigen Peptide Sequences for ZNF529 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 529 (ZN529_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF529: view

Function for ZNF529 Gene

Molecular function for ZNF529 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF529 Gene

Gene Ontology (GO) - Molecular Function for ZNF529 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0003700 DNA-binding transcription factor activity IBA 21873635
GO:0043565 sequence-specific DNA binding IBA 21873635
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF529: view
genes like me logo Genes that share phenotypes with ZNF529: view

Animal Model Products

CRISPR Products

miRNA for ZNF529 Gene

miRTarBase miRNAs that target ZNF529

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF529

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF529 Gene

Localization for ZNF529 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF529 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF529 gene
Compartment Confidence
nucleus 4
cytosol 3
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF529 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA 21873635
genes like me logo Genes that share ontologies with ZNF529: view

Pathways & Interactions for ZNF529 Gene

genes like me logo Genes that share pathways with ZNF529: view

Pathways by source for ZNF529 Gene

2 Reactome pathways for ZNF529 Gene
1 KEGG pathway for ZNF529 Gene

Gene Ontology (GO) - Biological Process for ZNF529 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF529: view

No data available for SIGNOR curated interactions for ZNF529 Gene

Drugs & Compounds for ZNF529 Gene

No Compound Related Data Available

Transcripts for ZNF529 Gene

mRNA/cDNA for ZNF529 Gene

12 NCBI additional mRNA sequence :
9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF529

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF529 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c
SP1: - -
SP2: -
SP4: - - -

Relevant External Links for ZNF529 Gene

GeneLoc Exon Structure for

Expression for ZNF529 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF529 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF529

SOURCE GeneReport for Unigene cluster for ZNF529 Gene:


Evidence on tissue expression from TISSUES for ZNF529 Gene

  • Nervous system(4.5)
  • Intestine(4.1)
genes like me logo Genes that share expression patterns with ZNF529: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF529 Gene

Orthologs for ZNF529 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF529 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF529 30 31
  • 99.29 (n)
(Bos Taurus)
Mammalia ZNF529 30
  • 86.58 (n)
(Canis familiaris)
Mammalia ZNF529 31
  • 80 (a)
Species where no ortholog for ZNF529 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ZNF529 Gene

Gene Tree for ZNF529 (if available)
Gene Tree for ZNF529 (if available)
Evolutionary constrained regions (ECRs) for ZNF529: view image

Paralogs for ZNF529 Gene

(531) SIMAP similar genes for ZNF529 Gene using alignment to 6 proteins:

  • ZN529_HUMAN
  • K7EL49_HUMAN
  • K7ES80_HUMAN
  • K7ESA1_HUMAN Pseudogenes for ZNF529 Gene

genes like me logo Genes that share paralogs with ZNF529: view

Variants for ZNF529 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF529 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs2912444 - p.Leu131Val

Additional dbSNP identifiers (rs#s) for ZNF529 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF529 Gene

Variant ID Type Subtype PubMed ID
dgv1778n106 CNV deletion 24896259
esv1008911 CNV deletion 20482838
esv1768990 CNV deletion 17803354
esv2205269 CNV deletion 18987734
esv2570514 CNV deletion 19546169
esv2664896 CNV deletion 23128226
esv2718504 CNV deletion 23290073
esv3556341 CNV deletion 23714750
esv3644261 CNV loss 21293372
esv3644264 CNV loss 21293372
nsv1056134 CNV loss 25217958
nsv1064851 CNV loss 25217958
nsv1071931 CNV deletion 25765185
nsv1146826 CNV deletion 26484159
nsv138053 CNV deletion 16902084
nsv833817 CNV loss 17160897

Variation tolerance for ZNF529 Gene

Residual Variation Intolerance Score: 46.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.13; 22.83% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF529 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF529 Gene

Disorders for ZNF529 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF529 Gene - From: DISEASES

Disorder Aliases PubMed IDs
n syndrome
  • nsx
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with ZNF529: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF529 Gene

Publications for ZNF529 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4
  5. Pooled-matrix protein interaction screens using Barcode Fusion Genetics. (PMID: 27107012) Yachie N … Roth FP (Molecular systems biology 2016) 3

Products for ZNF529 Gene

Sources for ZNF529 Gene