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ZNF518B (Zinc Finger Protein 518B) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity, RNA polymerase II-specific. An important paralog of this gene is ZNF518A.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003676 | nucleic acid binding | IEA | -- |
GO:0003677 | DNA binding | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006355 | regulation of transcription, DNA-templated | IBA | 21873635 |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ZNF518B 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | ZNF518B 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | ZNF518B 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Zfp518b 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Zfp518b 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | ZNF518B 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | ZNF518B 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | ZNF518B 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | ZNF518B 31 |
|
OneToOne | |
African clawed frog (Xenopus laevis) |
Amphibia | Xl.15195 30 |
|
||
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | Str.16698 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | ZNF518B 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 04 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs10007352 | - | p.Gly92Ser | |||
rs10016702 | - | p.Ser105Pro | |||
rs9291410 | - | p.Ser523Asn |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2759223 | CNV | loss | 17122850 |
esv3599589 | CNV | gain | 21293372 |
esv3599622 | CNV | gain | 21293372 |
esv3893876 | CNV | gain | 25118596 |
esv3893877 | CNV | loss | 25118596 |
nsv1014335 | CNV | gain | 25217958 |
nsv1122083 | CNV | deletion | 24896259 |
nsv517971 | CNV | gain | 19592680 |
nsv593727 | CNV | gain | 21841781 |
nsv829858 | CNV | gain+loss | 17160897 |
No disorders were found for ZNF518B Gene.