Aliases for ZNF511 Gene

Aliases for ZNF511 Gene

  • Zinc Finger Protein 511 2 3 4 5

External Ids for ZNF511 Gene

Previous GeneCards Identifiers for ZNF511 Gene

  • GC10P134595
  • GC10P135011
  • GC10P134973
  • GC10P135121
  • GC10P128668

Summaries for ZNF511 Gene

GeneCards Summary for ZNF511 Gene

ZNF511 (Zinc Finger Protein 511) is a Protein Coding gene.

UniProtKB/Swiss-Prot Summary for ZNF511 Gene

Additional gene information for ZNF511 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF511 Gene

Genomics for ZNF511 Gene

GeneHancer (GH) Regulatory Elements for ZNF511 Gene

Promoters and enhancers for ZNF511 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J133304 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 761.9 -1.4 -1405 5.3 ZNF24 SP1 ZBTB40 CTCF SMARCE1 POLR2A HCFC1 L3MBTL2 MAX RAD21 TUBGCP2 ZNF511 ZNF511-PRAP1 lnc-CALY-3 ENSG00000235245 ECHS1 VENTX ADAM8 piR-47693-001
GH10J133312 Promoter 0.5 EPDnew 750.6 +1.3 1304 0.1 GABPA POLR2A ZNF511 ZNF511-PRAP1 lnc-CALY-3 TUBGCP2
GH10J133310 Enhancer 0.4 ENCODE 750.6 +1.5 1473 0.1 SCRT2 GABPA POLR2A ZNF511 ZNF511-PRAP1 TUBGCP2 lnc-CALY-3
GH10J133311 Promoter 0.3 EPDnew 750.6 +2.8 2833 0.1 ZNF511 TUBGCP2 ZNF511-PRAP1
GH10J133257 Promoter/Enhancer 2.2 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 12.3 -48.5 -48470 6.6 SIN3A CTCF ZBTB6 POLR2A USF2 MYC L3MBTL2 MAX MNT ZNF280D HSALNG0081887 TUBGCP2 VENTX ENSG00000235245 SCART1 ZNF511 ADAM8 ECHS1 ENSG00000273980 lnc-VENTX-1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF511 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF511 gene promoter:
  • AP-2alpha
  • AP-2alpha isoform 2
  • AP-2alpha isoform 3
  • AP-2alpha isoform 4
  • AP-2alphaA
  • AREB6
  • Pax-2
  • Pax-2a
  • USF-1
  • USF1

Genomic Locations for ZNF511 Gene

Genomic Locations for ZNF511 Gene
chr10:133,308,889-133,313,162
(GRCh38/hg38)
Size:
4,274 bases
Orientation:
Plus strand
chr10:135,121,979-135,166,033
(GRCh37/hg19)
Size:
44,055 bases
Orientation:
Plus strand

Genomic View for ZNF511 Gene

Genes around ZNF511 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF511 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF511 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF511 Gene

Proteins for ZNF511 Gene

  • Protein details for ZNF511 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NB15-ZN511_HUMAN
    Recommended name:
    Zinc finger protein 511
    Protein Accession:
    Q8NB15
    Secondary Accessions:
    • A8K8L5
    • Q8WUP1
    • Q96BV2

    Protein attributes for ZNF511 Gene

    Size:
    252 amino acids
    Molecular mass:
    28265 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH15139.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF511 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF511 Gene

Post-translational modifications for ZNF511 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF511 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF511 Gene

Domains & Families for ZNF511 Gene

Gene Families for ZNF511 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted membrane proteins
  • Predicted secreted proteins
  • Transcription factors

Protein Domains for ZNF511 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF511 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 511 (ZN511_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8NB15

UniProtKB/Swiss-Prot:

ZN511_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF511: view

Function for ZNF511 Gene

Molecular function for ZNF511 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF511 Gene

Gene Ontology (GO) - Molecular Function for ZNF511 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific ISA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF511: view
genes like me logo Genes that share phenotypes with ZNF511: view

Animal Model Products

CRISPR Products

miRNA for ZNF511 Gene

miRTarBase miRNAs that target ZNF511

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF511

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF511 Gene

Localization for ZNF511 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF511 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF511 gene
Compartment Confidence
nucleus 3
endoplasmic reticulum 1
cytosol 0

Gene Ontology (GO) - Cellular Components for ZNF511 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF511: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF511 Gene

Pathways & Interactions for ZNF511 Gene

PathCards logo

SuperPathways for ZNF511 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF511 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZNF511: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF511 Gene

Drugs & Compounds for ZNF511 Gene

No Compound Related Data Available

Transcripts for ZNF511 Gene

mRNA/cDNA for ZNF511 Gene

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF511

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF511 Gene

No ASD Table

Relevant External Links for ZNF511 Gene

GeneLoc Exon Structure for
ZNF511
ECgene alternative splicing isoforms for
ZNF511

Expression for ZNF511 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF511 Gene

Protein differential expression in normal tissues from HIPED for ZNF511 Gene

This gene is overexpressed in Fetal ovary (25.0), Fetal testis (17.9), Fetal Liver (8.4), and CD8 Tcells (8.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF511 Gene



Protein tissue co-expression partners for ZNF511 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF511 Gene:

ZNF511

SOURCE GeneReport for Unigene cluster for ZNF511 Gene:

Hs.422113

Evidence on tissue expression from TISSUES for ZNF511 Gene

  • Nervous system(4.2)
  • Muscle(2.1)
genes like me logo Genes that share expression patterns with ZNF511: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF511 Gene

Orthologs for ZNF511 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ZNF511 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF511 33 32
  • 99.6 (n)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF511 33 32
  • 81.02 (n)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF511 33 32
  • 80.48 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp511 17 33 32
  • 77.37 (n)
rat
(Rattus norvegicus)
Mammalia Zfp511 32
  • 76.52 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 33
  • 75 (a)
OneToMany
-- 33
  • 60 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia ZNF511 33
  • 52 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF511 33 32
  • 68.12 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 33
  • 41 (a)
OneToMany
-- 33
  • 37 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia znf511 32
  • 57.81 (n)
zebrafish
(Danio rerio)
Actinopterygii znf511 33 32
  • 58.3 (n)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9628 32
fruit fly
(Drosophila melanogaster)
Insecta l(2)k10201 33
  • 25 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G14140 32
  • 47.67 (n)
rice
(Oryza sativa)
Liliopsida Os11g0498400 32
  • 51.65 (n)
Species where no ortholog for ZNF511 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF511 Gene

ENSEMBL:
Gene Tree for ZNF511 (if available)
TreeFam:
Gene Tree for ZNF511 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF511: view image

Paralogs for ZNF511 Gene

(1) SIMAP similar genes for ZNF511 Gene using alignment to 2 proteins:

  • ZN511_HUMAN
  • H7BY64_HUMAN

Pseudogenes.org Pseudogenes for ZNF511 Gene

genes like me logo Genes that share paralogs with ZNF511: view

No data available for Paralogs for ZNF511 Gene

Variants for ZNF511 Gene

Sequence variations from dbSNP and Humsavar for ZNF511 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000341421 -- 133,310,463(+) G/A intron_variant
rs1001109928 -- 133,307,195(+) C/T upstream_transcript_variant
rs1003761055 -- 133,313,547(+) C/T downstream_transcript_variant
rs1003766338 -- 133,313,208(+) A/C downstream_transcript_variant
rs1003999859 -- 133,308,678(+) CA/ upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF511 Gene

Variant ID Type Subtype PubMed ID
dgv122n27 CNV loss 19166990
dgv1475n54 CNV loss 21841781
dgv2e196 CNV duplication 17116639
dgv3e196 CNV duplication 17116639
esv2750853 CNV gain 17911159
esv2759793 CNV gain+loss 17122850
esv3625030 CNV gain 21293372
esv3625039 CNV loss 21293372
esv3625040 CNV gain 21293372
esv3891901 CNV loss 25118596
nsv1037772 CNV gain 25217958
nsv1040726 CNV loss 25217958
nsv1052904 CNV gain 25217958
nsv1159786 CNV deletion 26073780
nsv428243 CNV gain 18775914
nsv470980 CNV loss 18288195
nsv528260 CNV loss 19592680
nsv552589 CNV gain 21841781
nsv832036 CNV loss 17160897
nsv832038 CNV gain+loss 17160897
nsv832040 CNV loss 17160897

Variation tolerance for ZNF511 Gene

Residual Variation Intolerance Score: 45.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.37; 42.08% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF511 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF511

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF511 Gene

Disorders for ZNF511 Gene

Additional Disease Information for ZNF511

No disorders were found for ZNF511 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF511 Gene

Publications for ZNF511 Gene

  1. Recognition and suppression of transfected plasmids by protein ZNF511-PRAP1, a potential molecular barrier to transgene expression. (PMID: 21540836) Qiu GH … Hooi SC (Molecular therapy : the journal of the American Society of Gene Therapy 2011) 2 3 56
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4 56
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 56
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 56
  5. Mapping the Genetic Landscape of Human Cells. (PMID: 30033366) Horlbeck MA … Gilbert LA (Cell 2018) 3 56

Products for ZNF511 Gene

Sources for ZNF511 Gene