Aliases for ZNF511 Gene

Aliases for ZNF511 Gene

  • Zinc Finger Protein 511 2 3 4 5
  • Zfp511 2 3
  • MGC30006 2
  • ZNF511 5

External Ids for ZNF511 Gene

Previous GeneCards Identifiers for ZNF511 Gene

  • GC10P134595
  • GC10P135011
  • GC10P134973
  • GC10P135121
  • GC10P128668

Summaries for ZNF511 Gene

GeneCards Summary for ZNF511 Gene

ZNF511 (Zinc Finger Protein 511) is a Protein Coding gene.

UniProtKB/Swiss-Prot Summary for ZNF511 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF511 Gene

Genomics for ZNF511 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF511 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J133304 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 250.7 -1.4 -1430 5.3 SP1 ZNF654 ZNF207 MYC NCOR1 JUND ZNF592 ATF2 POLR2A BRCA1 TUBGCP2 lnc-CALY-3 ZNF511 ZNF511-PRAP1 ECHS1 VENTX ADAM8 piR-47693-001
GH10J133312 Promoter 0.5 EPDnew 250.7 +1.3 1279 0.1 GABPA POLR2A lnc-CALY-3 ZNF511 ZNF511-PRAP1 TUBGCP2
GH10J133310 Enhancer 0.4 ENCODE 250.7 +1.4 1448 0.1 GABPA POLR2A SCRT2 lnc-CALY-3 TUBGCP2 ZNF511 ZNF511-PRAP1
GH10J133311 Promoter 0.3 EPDnew 250.7 +2.8 2808 0.1 TUBGCP2 ZNF511 ZNF511-PRAP1
GH10J132392 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 18.8 -900.5 -900512 32.2 ZNF600 MYC ZNF580 ZNF592 ZNF223 ZIC2 POLR2A CTCF CEBPB DEK PWWP2B TUBGCP2 ENSG00000235245 LINC02870 ZNF511 STK32C ENSG00000234311 PAOX MTG1 LRRC27
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF511 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF511

Top Transcription factor binding sites by QIAGEN in the ZNF511 gene promoter:
  • AP-2alpha
  • AP-2alpha isoform 2
  • AP-2alpha isoform 3
  • AP-2alpha isoform 4
  • AP-2alphaA
  • AREB6
  • Pax-2
  • Pax-2a
  • USF-1
  • USF1

Genomic Locations for ZNF511 Gene

Latest Assembly
chr10:133,308,914-133,313,162
(GRCh38/hg38)
Size:
4,249 bases
Orientation:
Plus strand

Previous Assembly
chr10:135,122,418-135,126,665
(GRCh37/hg19 by Entrez Gene)
Size:
4,248 bases
Orientation:
Plus strand

chr10:135,121,979-135,166,033
(GRCh37/hg19 by Ensembl)
Size:
44,055 bases
Orientation:
Plus strand

Genomic View for ZNF511 Gene

Genes around ZNF511 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF511 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF511 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF511 Gene

Proteins for ZNF511 Gene

  • Protein details for ZNF511 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NB15-ZN511_HUMAN
    Recommended name:
    Zinc finger protein 511
    Protein Accession:
    Q8NB15
    Secondary Accessions:
    • A8K8L5
    • Q8WUP1
    • Q96BV2

    Protein attributes for ZNF511 Gene

    Size:
    252 amino acids
    Molecular mass:
    28265 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH15139.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF511 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF511 Gene

Post-translational modifications for ZNF511 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF511 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF511 Gene

Domains & Families for ZNF511 Gene

Gene Families for ZNF511 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Transcription factors

Protein Domains for ZNF511 Gene

Suggested Antigen Peptide Sequences for ZNF511 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 511 (ZN511_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8NB15

UniProtKB/Swiss-Prot:

ZN511_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF511: view

Function for ZNF511 Gene

Molecular function for ZNF511 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF511 Gene

Gene Ontology (GO) - Molecular Function for ZNF511 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific ISA --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF511: view
genes like me logo Genes that share phenotypes with ZNF511: view

miRNA for ZNF511 Gene

miRTarBase miRNAs that target ZNF511

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF511

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF511 Gene

Localization for ZNF511 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF511 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF511 gene
Compartment Confidence
nucleus 3
endoplasmic reticulum 1
cytosol 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (2)
  • Nucleoplasm (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF511 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000785 chromatin ISA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF511: view

Pathways & Interactions for ZNF511 Gene

PathCards logo

SuperPathways for ZNF511 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF511 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZNF511: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF511 Gene

Drugs & Compounds for ZNF511 Gene

No Compound Related Data Available

Transcripts for ZNF511 Gene

mRNA/cDNA for ZNF511 Gene

1 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF511

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF511 Gene

No ASD Table

Relevant External Links for ZNF511 Gene

GeneLoc Exon Structure for
ZNF511

Expression for ZNF511 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF511 Gene

Protein differential expression in normal tissues from HIPED for ZNF511 Gene

This gene is overexpressed in Fetal ovary (25.0), Fetal testis (17.9), Fetal Liver (8.4), and CD8 Tcells (8.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF511 Gene



Protein tissue co-expression partners for ZNF511 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF511

SOURCE GeneReport for Unigene cluster for ZNF511 Gene:

Hs.422113

Evidence on tissue expression from TISSUES for ZNF511 Gene

  • Nervous system(4.2)
  • Muscle(2.1)
genes like me logo Genes that share expression patterns with ZNF511: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF511 Gene

Orthologs for ZNF511 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ZNF511 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ZNF511 29 30
  • 99.6 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia ZNF511 29 30
  • 81.02 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia ZNF511 29 30
  • 80.48 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Zfp511 29 16 30
  • 77.37 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Zfp511 29
  • 76.52 (n)
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 30
  • 75 (a)
OneToMany
-- 30
  • 60 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia ZNF511 30
  • 52 (a)
OneToOne
Chicken
(Gallus gallus)
Aves ZNF511 29 30
  • 68.12 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia -- 30
  • 41 (a)
OneToMany
-- 30
  • 37 (a)
OneToMany
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia znf511 29
  • 57.81 (n)
Zebrafish
(Danio rerio)
Actinopterygii znf511 29 30
  • 58.3 (n)
OneToOne
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9628 29
Fruit Fly
(Drosophila melanogaster)
Insecta l(2)k10201 30
  • 25 (a)
OneToOne
Thale Cress
(Arabidopsis thaliana)
eudicotyledons AT5G14140 29
  • 47.67 (n)
Rice
(Oryza sativa)
Liliopsida Os11g0498400 29
  • 51.65 (n)
Species where no ortholog for ZNF511 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for ZNF511 Gene

ENSEMBL:
Gene Tree for ZNF511 (if available)
TreeFam:
Gene Tree for ZNF511 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF511: view image
Alliance of Genome Resources:
Additional Orthologs for ZNF511

Paralogs for ZNF511 Gene

(1) SIMAP similar genes for ZNF511 Gene using alignment to 2 proteins:

  • ZN511_HUMAN
  • H7BY64_HUMAN

Pseudogenes.org Pseudogenes for ZNF511 Gene

genes like me logo Genes that share paralogs with ZNF511: view

No data available for Paralogs for ZNF511 Gene

Variants for ZNF511 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for ZNF511 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for ZNF511 Gene

Variant ID Type Subtype PubMed ID
dgv122n27 CNV loss 19166990
dgv1475n54 CNV loss 21841781
dgv2e196 CNV duplication 17116639
dgv3e196 CNV duplication 17116639
esv2750853 CNV gain 17911159
esv2759793 CNV gain+loss 17122850
esv3625030 CNV gain 21293372
esv3625039 CNV loss 21293372
esv3625040 CNV gain 21293372
esv3891901 CNV loss 25118596
nsv1037772 CNV gain 25217958
nsv1040726 CNV loss 25217958
nsv1052904 CNV gain 25217958
nsv1159786 CNV deletion 26073780
nsv428243 CNV gain 18775914
nsv470980 CNV loss 18288195
nsv528260 CNV loss 19592680
nsv552589 CNV gain 21841781
nsv832036 CNV loss 17160897
nsv832038 CNV gain+loss 17160897
nsv832040 CNV loss 17160897

Variation tolerance for ZNF511 Gene

Residual Variation Intolerance Score: 45.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.37; 42.08% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF511 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF511
Leiden Open Variation Database (LOVD)
ZNF511

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF511 Gene

Disorders for ZNF511 Gene

Additional Disease Information for ZNF511

No disorders were found for ZNF511 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF511 Gene

Publications for ZNF511 Gene

  1. Recognition and suppression of transfected plasmids by protein ZNF511-PRAP1, a potential molecular barrier to transgene expression. (PMID: 21540836) Qiu GH … Hooi SC (Molecular therapy : the journal of the American Society of Gene Therapy 2011) 2 3
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  5. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3

Products for ZNF511 Gene

Sources for ZNF511 Gene