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Aliases for ZNF510 Gene

Aliases for ZNF510 Gene

  • Zinc Finger Protein 510 2 3 5
  • KIAA0972 4

External Ids for ZNF510 Gene

Previous GeneCards Identifiers for ZNF510 Gene

  • GC09M094897
  • GC09M096597
  • GC09M098557
  • GC09M099518
  • GC09M069128

Summaries for ZNF510 Gene

Entrez Gene Summary for ZNF510 Gene

  • This gene encodes a krueppel C2H2-type zinc-finger protein family member. The encoded protein is expressed in several cancer cell types and may be a biomarker for early diagnosis of these cancers. [provided by RefSeq, Sep 2015]

GeneCards Summary for ZNF510 Gene

ZNF510 (Zinc Finger Protein 510) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF33B.

UniProtKB/Swiss-Prot for ZNF510 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF510 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF510 Gene

Genomics for ZNF510 Gene

GeneHancer (GH) Regulatory Elements for ZNF510 Gene

Promoters and enhancers for ZNF510 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I096776 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 +0.1 136 2.1 PKNOX1 SMAD1 FOXA2 ARNT ARID4B SIN3A ZNF2 YY1 POLR2B E2F8 ZNF510 GC09P096778 NUTM2G PIR50621
GH09I097510 Enhancer 1.3 Ensembl ENCODE dbSUPER 39.1 -733.1 -733149 2.1 HDGF PKNOX1 TCF12 ATF7 FOS RUNX3 KLF13 YY2 JUNB ZNF662 ZNF510 ENSG00000224848 ZNF322P1 NCBP1 XPA TSTD2 LOC105376168 LOC105376171 ZNF782 LOC441455
GH09I095874 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 14.7 +902.1 902077 3.4 CLOCK MLX ZFP64 DMAP1 IRF4 YY1 E2F8 ZNF143 ZNF548 SP3 ERCC6L2 LINC00476 ENSG00000271155 ZNF510 LOC158435 ENSG00000271659 GC09P095906
GH09I096653 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 14.8 +123.4 123437 3 ATF1 FOXA2 ARNT SIN3A GTF3C2 ZNF766 GLIS2 ZNF207 SP3 REST AAED1 ZNF322P1 ZNF510 CDC14B LINC00476 NCBP1 CCDC180 ERCC6L2 ZNF782 CTSV
GH09I097695 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 14.7 -919.0 -919047 2.8 HDGF CLOCK ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B XPA KRT18P13 ZNF322P1 ZNF510 NCBP1 CCDC180 ZNF782 TSTD2 GC09M097677
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF510 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF510 gene promoter:

Genomic Locations for ZNF510 Gene

Genomic Locations for ZNF510 Gene
23,577 bases
Minus strand

Genomic View for ZNF510 Gene

Genes around ZNF510 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF510 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF510 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF510 Gene

Proteins for ZNF510 Gene

  • Protein details for ZNF510 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 510
    Protein Accession:
    Secondary Accessions:
    • Q5SZP5

    Protein attributes for ZNF510 Gene

    683 amino acids
    Molecular mass:
    79142 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA76816.2; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF510 Gene

Post-translational modifications for ZNF510 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF510 Gene

No data available for DME Specific Peptides for ZNF510 Gene

Domains & Families for ZNF510 Gene

Gene Families for ZNF510 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF510: view

Function for ZNF510 Gene

Molecular function for ZNF510 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF510 Gene

Gene Ontology (GO) - Molecular Function for ZNF510 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF510: view
genes like me logo Genes that share phenotypes with ZNF510: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF510 Gene

Localization for ZNF510 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF510 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF510 gene
Compartment Confidence
nucleus 5
mitochondrion 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF510 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF510: view

Pathways & Interactions for ZNF510 Gene

SuperPathways for ZNF510 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF510: view

Pathways by source for ZNF510 Gene

2 Reactome pathways for ZNF510 Gene

Gene Ontology (GO) - Biological Process for ZNF510 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF510: view

No data available for SIGNOR curated interactions for ZNF510 Gene

Drugs & Compounds for ZNF510 Gene

No Compound Related Data Available

Transcripts for ZNF510 Gene

Unigene Clusters for ZNF510 Gene

Zinc finger protein 510:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF510 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c
SP1: -
SP3: -
SP4: - -
SP5: - - - - -

Relevant External Links for ZNF510 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF510 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF510 Gene

Protein differential expression in normal tissues from HIPED for ZNF510 Gene

This gene is overexpressed in Liver (67.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF510 Gene

Protein tissue co-expression partners for ZNF510 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF510 Gene:


SOURCE GeneReport for Unigene cluster for ZNF510 Gene:


Evidence on tissue expression from TISSUES for ZNF510 Gene

  • Nervous system(4.6)
  • Saliva(2.3)
genes like me logo Genes that share expression patterns with ZNF510: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF510 Gene

Orthologs for ZNF510 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF510 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF510 33 34
  • 98.93 (n)
(Canis familiaris)
Mammalia ZNF510 34
  • 75 (a)
(Bos Taurus)
Mammalia -- 34
  • 38 (a)
(Mus musculus)
Mammalia Zfp663 34
  • 33 (a)
Species where no ortholog for ZNF510 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF510 Gene

Gene Tree for ZNF510 (if available)
Gene Tree for ZNF510 (if available)

Paralogs for ZNF510 Gene

(503) SIMAP similar genes for ZNF510 Gene using alignment to 3 proteins: Pseudogenes for ZNF510 Gene

genes like me logo Genes that share paralogs with ZNF510: view

Variants for ZNF510 Gene

Sequence variations from dbSNP and Humsavar for ZNF510 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000060708 -- 96,754,154(-) T/G downstream_transcript_variant
rs1000114908 -- 96,778,507(-) G/A 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant
rs1000117587 -- 96,757,727(-) T/C 3_prime_UTR_variant
rs1000130902 -- 96,760,224(-) A/G coding_sequence_variant, synonymous_variant
rs1000134114 -- 96,766,810(-) AGGAG/AGGAGGAG intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF510 Gene

Variant ID Type Subtype PubMed ID
nsv1147999 OTHER inversion 26484159
nsv520001 CNV loss 19592680
nsv831660 CNV gain 17160897

Variation tolerance for ZNF510 Gene

Residual Variation Intolerance Score: 79.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.18; 80.85% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF510 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF510 Gene

Disorders for ZNF510 Gene

Additional Disease Information for ZNF510

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for ZNF510 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF510 Gene

Publications for ZNF510 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10231032) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1999) 2 3 4 58
  2. Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci. (PMID: 19030899) Lei SF … Deng HW (Human genetics 2009) 3 44 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M … Gstaiger M (Cell reports 2013) 3 58
  5. Salivary zinc finger protein 510 peptide as a novel biomarker for detection of oral squamous cell carcinoma in early stages. (PMID: 21497587) Jou YJ … Lin CW (Clinica chimica acta; international journal of clinical chemistry 2011) 3 58

Products for ZNF510 Gene

Sources for ZNF510 Gene

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