Aliases for ZNF507 Gene

Aliases for ZNF507 Gene

  • Zinc Finger Protein 507 2 3 4 5
  • KIAA1084 4

External Ids for ZNF507 Gene

Previous GeneCards Identifiers for ZNF507 Gene

  • GC19P037528
  • GC19P037433
  • GC19P032836
  • GC19P029339

Summaries for ZNF507 Gene

GeneCards Summary for ZNF507 Gene

ZNF507 (Zinc Finger Protein 507) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF407.

UniProtKB/Swiss-Prot Summary for ZNF507 Gene

Additional gene information for ZNF507 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF507 Gene

Genomics for ZNF507 Gene

GeneHancer (GH) Regulatory Elements for ZNF507 Gene

Promoters and enhancers for ZNF507 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF507 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF507 gene promoter:
  • Arnt
  • CUTL1
  • E2F
  • E2F-1
  • E2F-2
  • E2F-3a
  • E2F-4
  • E2F-5
  • GATA-1
  • HFH-1

Genomic Locations for ZNF507 Gene

Genomic Locations for ZNF507 Gene
42,074 bases
Plus strand
42,074 bases
Plus strand

Genomic View for ZNF507 Gene

Genes around ZNF507 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF507 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF507 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF507 Gene

Proteins for ZNF507 Gene

  • Protein details for ZNF507 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 507
    Protein Accession:
    Secondary Accessions:
    • A8K911
    • Q2TBF1
    • Q6MZU0
    • Q9UPR8

    Protein attributes for ZNF507 Gene

    953 amino acids
    Molecular mass:
    105767 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA83036.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAD28536.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAD28536.1; Type=Frameshift; Positions=56; Evidence={ECO:0000305}; Sequence=CAE45937.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF507 Gene


neXtProt entry for ZNF507 Gene

Post-translational modifications for ZNF507 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF507 Gene

No data available for DME Specific Peptides for ZNF507 Gene

Domains & Families for ZNF507 Gene

Gene Families for ZNF507 Gene

Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF507 Gene


Suggested Antigen Peptide Sequences for ZNF507 Gene

GenScript: Design optimal peptide antigens:
  • ZNF507 protein (B9EGE7_HUMAN)
  • Zinc finger protein 507 (ZN507_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF507: view

Function for ZNF507 Gene

Molecular function for ZNF507 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF507 Gene

Gene Ontology (GO) - Molecular Function for ZNF507 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IBA 21873635
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific ISA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF507: view
genes like me logo Genes that share phenotypes with ZNF507: view

Animal Model Products

CRISPR Products

miRNA for ZNF507 Gene

miRTarBase miRNAs that target ZNF507

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF507 Gene

Localization for ZNF507 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF507 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF507 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Nucleoli (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF507 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 colocalizes_with nucleus IBA 21873635
GO:0035097 colocalizes_with histone methyltransferase complex IBA 21873635
genes like me logo Genes that share ontologies with ZNF507: view

Pathways & Interactions for ZNF507 Gene

PathCards logo

SuperPathways for ZNF507 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF507 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription by RNA polymerase II IEA --
GO:0010468 regulation of gene expression IBA 21873635
genes like me logo Genes that share ontologies with ZNF507: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF507 Gene

Drugs & Compounds for ZNF507 Gene

No Compound Related Data Available

Transcripts for ZNF507 Gene

mRNA/cDNA for ZNF507 Gene

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF507 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7
SP1: - -

Relevant External Links for ZNF507 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF507 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF507 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF507 Gene

Protein tissue co-expression partners for ZNF507 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF507 Gene:


SOURCE GeneReport for Unigene cluster for ZNF507 Gene:


Evidence on tissue expression from TISSUES for ZNF507 Gene

  • Intestine(4.2)
  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF507: view

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF507 Gene

Orthologs for ZNF507 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF507 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF507 33 32
  • 99.51 (n)
(Bos Taurus)
Mammalia ZNF507 33 32
  • 87.99 (n)
(Canis familiaris)
Mammalia ZNF507 33 32
  • 87.37 (n)
(Mus musculus)
Mammalia Zfp507 17 33 32
  • 80.69 (n)
(Rattus norvegicus)
Mammalia Zfp507 32
  • 80.38 (n)
(Ornithorhynchus anatinus)
Mammalia ZNF507 33
  • 72 (a)
(Monodelphis domestica)
Mammalia ZNF507 33
  • 72 (a)
(Gallus gallus)
Aves ZNF507 33 32
  • 69.34 (n)
(Anolis carolinensis)
Reptilia ZNF507 33
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia znf507 32
  • 62.09 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.32184 32
(Danio rerio)
Actinopterygii znf507 32
  • 53.06 (n)
ZNF507 33
  • 17 (a)
Species where no ortholog for ZNF507 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF507 Gene

Gene Tree for ZNF507 (if available)
Gene Tree for ZNF507 (if available)
Evolutionary constrained regions (ECRs) for ZNF507: view image

Paralogs for ZNF507 Gene

Variants for ZNF507 Gene

Sequence variations from dbSNP and Humsavar for ZNF507 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000013606 -- 32,386,883(+) G/A/T 3_prime_UTR_variant
rs1000066369 -- 32,361,226(+) G/A intron_variant
rs1000222294 -- 32,345,281(+) /G upstream_transcript_variant
rs1000310411 -- 32,380,364(+) A/G intron_variant
rs1000373598 -- 32,374,346(+) A/C/T intron_variant

Variation tolerance for ZNF507 Gene

Residual Variation Intolerance Score: 2.58% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.89; 35.27% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF507 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF507 Gene

Disorders for ZNF507 Gene

Additional Disease Information for ZNF507

No disorders were found for ZNF507 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF507 Gene

Publications for ZNF507 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10470851) Kikuno R … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1999) 3 4 56
  2. VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3 56
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 56
  4. Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways. (PMID: 26972000) Rodriguez J … von Kriegsheim A (Cell reports 2016) 3 56
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 56

Products for ZNF507 Gene

Sources for ZNF507 Gene