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Aliases for ZNF507 Gene

Aliases for ZNF507 Gene

  • Zinc Finger Protein 507 2 3 5
  • KIAA1084 4

External Ids for ZNF507 Gene

Previous GeneCards Identifiers for ZNF507 Gene

  • GC19P037528
  • GC19P037433
  • GC19P032836
  • GC19P029339

Summaries for ZNF507 Gene

GeneCards Summary for ZNF507 Gene

ZNF507 (Zinc Finger Protein 507) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for ZNF507 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF507 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF507 Gene

Genomics for ZNF507 Gene

GeneHancer (GH) Regulatory Elements for ZNF507 Gene

Promoters and enhancers for ZNF507 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I032343 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 608.1 -0.3 -266 4.4 MLX ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B YY1 ZNF766 ZNF507 GPATCH1 CEP89 PDCD5 FAAP24 DPY19L3 LOC400684 ANKRD27 GC19M032297
GH19I033296 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 108.7 +955.8 955812 10.6 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF213 ZNF416 ZNF143 CEBPA-AS1 CEBPA ENSG00000267580 ENSG00000267727 GC19M033302 GPATCH1 ZNF507 CEP89 LSM14A KIAA0355
GH19I033273 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 136.5 +929.5 929459 3.3 CLOCK FOXA2 MLX ARID4B DMAP1 ZNF2 YY1 ZNF302 ZNF416 ZNF548 GPATCH1 ZNF507 CEP89 LSM14A KIAA0355 PDCD5 CEBPG WDR88 FAAP24 DPY19L3
GH19I033247 Enhancer 1.4 Ensembl ENCODE dbSUPER 137.9 +903.3 903277 3 HDGF FOXA2 YBX1 ZNF2 ZBTB7B YY1 ZNF207 ZNF548 FOS ZNF662 GPATCH1 CEP89 ZNF507 LSM14A FAAP24 PDCD5 WDR88 SLC7A10 PIR37620
GH19I033175 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE 82.9 +831.5 831546 2.7 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 ZFP41 LRP3 ENSG00000267054 GC19M033175 TRT-AGT1-3 GPATCH1 CEP89 ZNF507 LSM14A WDR88 PDCD5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF507 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF507 gene promoter:

Genomic Locations for ZNF507 Gene

Genomic Locations for ZNF507 Gene
chr19:32,345,594-32,387,667
(GRCh38/hg38)
Size:
42,074 bases
Orientation:
Plus strand
chr19:32,836,500-32,878,573
(GRCh37/hg19)

Genomic View for ZNF507 Gene

Genes around ZNF507 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF507 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF507 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF507 Gene

Proteins for ZNF507 Gene

  • Protein details for ZNF507 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TCN5-ZN507_HUMAN
    Recommended name:
    Zinc finger protein 507
    Protein Accession:
    Q8TCN5
    Secondary Accessions:
    • A8K911
    • Q2TBF1
    • Q6MZU0
    • Q9UPR8

    Protein attributes for ZNF507 Gene

    Size:
    953 amino acids
    Molecular mass:
    105767 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA83036.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAD28536.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAD28536.1; Type=Frameshift; Positions=56; Evidence={ECO:0000305}; Sequence=CAE45937.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF507 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF507 Gene

Post-translational modifications for ZNF507 Gene

No Post-translational modifications

Other Protein References for ZNF507 Gene

No data available for DME Specific Peptides for ZNF507 Gene

Domains & Families for ZNF507 Gene

Gene Families for ZNF507 Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF507 Gene

Suggested Antigen Peptide Sequences for ZNF507 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8TCN5

UniProtKB/Swiss-Prot:

ZN507_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF507: view

Function for ZNF507 Gene

Molecular function for ZNF507 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF507 Gene

Gene Ontology (GO) - Molecular Function for ZNF507 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF507: view
genes like me logo Genes that share phenotypes with ZNF507: view

miRNA for ZNF507 Gene

miRTarBase miRNAs that target ZNF507

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF507 Gene

Localization for ZNF507 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF507 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF507 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Nucleoli (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF507 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF507: view

Pathways & Interactions for ZNF507 Gene

SuperPathways for ZNF507 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF507 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF507: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF507 Gene

Drugs & Compounds for ZNF507 Gene

No Compound Related Data Available

Transcripts for ZNF507 Gene

Unigene Clusters for ZNF507 Gene

Zinc finger protein 507:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF507 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7
SP1: - -
SP2:

Relevant External Links for ZNF507 Gene

GeneLoc Exon Structure for
ZNF507
ECgene alternative splicing isoforms for
ZNF507

Expression for ZNF507 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF507 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF507 Gene



Protein tissue co-expression partners for ZNF507 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF507 Gene:

ZNF507

SOURCE GeneReport for Unigene cluster for ZNF507 Gene:

Hs.205392

Evidence on tissue expression from TISSUES for ZNF507 Gene

  • Intestine(4.2)
  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF507: view

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF507 Gene

Orthologs for ZNF507 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF507 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF507 33 34
  • 99.51 (n)
cow
(Bos Taurus)
Mammalia ZNF507 33 34
  • 87.99 (n)
dog
(Canis familiaris)
Mammalia ZNF507 33 34
  • 87.37 (n)
mouse
(Mus musculus)
Mammalia Zfp507 33 16 34
  • 80.69 (n)
rat
(Rattus norvegicus)
Mammalia Zfp507 33
  • 80.38 (n)
oppossum
(Monodelphis domestica)
Mammalia ZNF507 34
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF507 34
  • 72 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF507 33 34
  • 69.34 (n)
lizard
(Anolis carolinensis)
Reptilia ZNF507 34
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia znf507 33
  • 62.09 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.32184 33
zebrafish
(Danio rerio)
Actinopterygii znf507 33
  • 53.06 (n)
ZNF507 34
  • 17 (a)
OneToOne
Species where no ortholog for ZNF507 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF507 Gene

ENSEMBL:
Gene Tree for ZNF507 (if available)
TreeFam:
Gene Tree for ZNF507 (if available)

Paralogs for ZNF507 Gene

(9) SIMAP similar genes for ZNF507 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF507: view

No data available for Paralogs for ZNF507 Gene

Variants for ZNF507 Gene

Sequence variations from dbSNP and Humsavar for ZNF507 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000013606 -- 32,386,883(+) G/A/T 3_prime_UTR_variant
rs1000066369 -- 32,361,226(+) G/A intron_variant
rs1000222294 -- 32,345,281(+) /G upstream_transcript_variant
rs1000310411 -- 32,380,364(+) A/G intron_variant
rs1000373598 -- 32,374,346(+) A/C/T intron_variant

Variation tolerance for ZNF507 Gene

Residual Variation Intolerance Score: 2.58% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.89; 35.27% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF507 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF507

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF507 Gene

Disorders for ZNF507 Gene

Additional Disease Information for ZNF507

No disorders were found for ZNF507 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF507 Gene

Publications for ZNF507 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10470851) Kikuno R … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1999) 3 4 58
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58
  5. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H … Mohammed S (Journal of proteome research 2013) 4 58

Products for ZNF507 Gene

Sources for ZNF507 Gene

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