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Aliases for ZNF502 Gene

Aliases for ZNF502 Gene

  • Zinc Finger Protein 502 2 3 5

External Ids for ZNF502 Gene

Previous GeneCards Identifiers for ZNF502 Gene

  • GC03P044714
  • GC03P044559
  • GC03P044729
  • GC03P044754
  • GC03P044756
  • GC03P044833
  • GC03P044841
  • GC03P044910
  • GC03P044947
  • GC03P044990

Summaries for ZNF502 Gene

GeneCards Summary for ZNF502 Gene

ZNF502 (Zinc Finger Protein 502) is a Protein Coding gene. An important paralog of this gene is ZNF135.

UniProtKB/Swiss-Prot for ZNF502 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF502 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF502 Gene

Genomics for ZNF502 Gene

GeneHancer (GH) Regulatory Elements for ZNF502 Gene

Promoters and enhancers for ZNF502 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I044712 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE 578.2 +0.2 182 1.6 ATF1 ZNF76 SIN3A ZBTB40 RAD21 YY1 ETS1 ZNF335 E2F8 ZNF143 ZNF502 SOCS5P3 ZNF852 ZNF35 ZDHHC3 LOC105377056
GH03I045687 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 27.7 +979.3 979253 8.2 ZFP64 FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 SP3 NFYC SACM1L ZNF502 LIMD1 RN7SL145P RPS24P8 ZNF501 ZDHHC3 LARS2-AS1 SDHDP4 CCR9
GH03I045052 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 29.2 +346.9 346886 13.7 HDGF PKNOX1 ARNT YY1 POLR2B ZNF766 E2F8 ZNF143 FOS REST ZNF502 ZNF852 RN7SL145P CLEC3B ZNF35 CDCP1 ZNF197 ZNF660 EXOSC7 RNU5B-3P
GH03I045130 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 25.8 +423.3 423348 11.1 HDGF PKNOX1 SMAD1 ARNT POLR2B ZNF766 CBX5 E2F8 FOS REST ZNF502 ZNF852 RN7SL145P ZNF35 ZNF197 RNU5B-3P CLEC3B TMEM158 SACM1L ZDHHC3
GH03I044860 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 18.7 +149.3 149340 2.1 ARID4B DMAP1 ZNF48 YY1 ZNF121 GLIS2 ZNF207 ZNF143 FOS RUNX3 TMEM42 GC03P045070 GC03P045071 MIR564 ZNF502 PPIAP18 KIF15
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF502 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF502 gene promoter:

Genomic Locations for ZNF502 Gene

Genomic Locations for ZNF502 Gene
chr3:44,712,643-44,723,831
(GRCh38/hg38)
Size:
11,189 bases
Orientation:
Plus strand
chr3:44,754,135-44,765,323
(GRCh37/hg19)

Genomic View for ZNF502 Gene

Genes around ZNF502 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF502 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF502 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF502 Gene

Proteins for ZNF502 Gene

  • Protein details for ZNF502 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TBZ5-ZN502_HUMAN
    Recommended name:
    Zinc finger protein 502
    Protein Accession:
    Q8TBZ5

    Protein attributes for ZNF502 Gene

    Size:
    544 amino acids
    Molecular mass:
    62920 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF502 Gene

Post-translational modifications for ZNF502 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZNF502 Gene

Domains & Families for ZNF502 Gene

Gene Families for ZNF502 Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF502 Gene

Suggested Antigen Peptide Sequences for ZNF502 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8TBZ5

UniProtKB/Swiss-Prot:

ZN502_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF502: view

Function for ZNF502 Gene

Molecular function for ZNF502 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF502 Gene

Gene Ontology (GO) - Molecular Function for ZNF502 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF502: view
genes like me logo Genes that share phenotypes with ZNF502: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF502 Gene

Localization for ZNF502 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF502 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF502 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF502 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 25556234
genes like me logo Genes that share ontologies with ZNF502: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF502 Gene

Pathways & Interactions for ZNF502 Gene

SuperPathways for ZNF502 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF502 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0044791 positive regulation by host of viral release from host cell IMP 25556234
GO:0044794 positive regulation by host of viral process IMP 25556234
genes like me logo Genes that share ontologies with ZNF502: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF502 Gene

Drugs & Compounds for ZNF502 Gene

No Compound Related Data Available

Transcripts for ZNF502 Gene

Unigene Clusters for ZNF502 Gene

Zinc finger protein 502:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF502 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d · 5e
SP1:
SP2: -
SP3: -
SP4: - -
SP5: - -

Relevant External Links for ZNF502 Gene

GeneLoc Exon Structure for
ZNF502
ECgene alternative splicing isoforms for
ZNF502

Expression for ZNF502 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF502 Gene

Protein differential expression in normal tissues from HIPED for ZNF502 Gene

This gene is overexpressed in Fetal testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF502 Gene



Protein tissue co-expression partners for ZNF502 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF502 Gene:

ZNF502

SOURCE GeneReport for Unigene cluster for ZNF502 Gene:

Hs.224843
genes like me logo Genes that share expression patterns with ZNF502: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF502 Gene

Orthologs for ZNF502 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF502 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF502 33 34
  • 99.45 (n)
dog
(Canis familiaris)
Mammalia ZNF502 33 34
  • 91.68 (n)
cow
(Bos Taurus)
Mammalia ZNF502 33 34
  • 90.66 (n)
rat
(Rattus norvegicus)
Mammalia LOC100911237 33
  • 67.03 (n)
mouse
(Mus musculus)
Mammalia Zfp72 33 16
  • 65.42 (n)
oppossum
(Monodelphis domestica)
Mammalia ZNF502 34
  • 63 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 34
  • 49 (a)
OneToMany
Species where no ortholog for ZNF502 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF502 Gene

ENSEMBL:
Gene Tree for ZNF502 (if available)
TreeFam:
Gene Tree for ZNF502 (if available)

Paralogs for ZNF502 Gene

(471) SIMAP similar genes for ZNF502 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF502: view

Variants for ZNF502 Gene

Sequence variations from dbSNP and Humsavar for ZNF502 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000390923 -- 44,720,078(+) G/C 5_prime_UTR_variant, intron_variant
rs1000892095 -- 44,711,835(+) G/A upstream_transcript_variant
rs1000920632 -- 44,718,826(+) C/T 5_prime_UTR_variant, intron_variant
rs1001082922 -- 44,712,219(+) G/C upstream_transcript_variant
rs1001122342 -- 44,718,614(+) G/A genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant

Variation tolerance for ZNF502 Gene

Residual Variation Intolerance Score: 50.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.95; 74.58% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF502 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF502

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF502 Gene

Disorders for ZNF502 Gene

Additional Disease Information for ZNF502

No disorders were found for ZNF502 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF502 Gene

Publications for ZNF502 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  2. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  3. New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein. (PMID: 25556234) Kipper S … Bajorek M (Molecular & cellular proteomics : MCP 2015) 3 58
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  5. An atlas of combinatorial transcriptional regulation in mouse and man. (PMID: 20211142) Ravasi T … Hayashizaki Y (Cell 2010) 3 58

Products for ZNF502 Gene

Sources for ZNF502 Gene

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