Aliases for ZNF502 Gene

Aliases for ZNF502 Gene

  • Zinc Finger Protein 502 2 3 4 5

External Ids for ZNF502 Gene

Previous GeneCards Identifiers for ZNF502 Gene

  • GC03P044714
  • GC03P044559
  • GC03P044729
  • GC03P044754
  • GC03P044756
  • GC03P045170
  • GC03P045203
  • GC03P045223
  • GC03P044833
  • GC03P044841
  • GC03P044910
  • GC03P044947
  • GC03P044990
  • GC03P045032
  • GC03P045071
  • GC03P045107

Summaries for ZNF502 Gene

GeneCards Summary for ZNF502 Gene

ZNF502 (Zinc Finger Protein 502) is a Protein Coding gene. Diseases associated with ZNF502 include Seminal Vesicle Tumor. An important paralog of this gene is ZNF93.

UniProtKB/Swiss-Prot Summary for ZNF502 Gene

Additional gene information for ZNF502 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF502 Gene

Genomics for ZNF502 Gene

GeneHancer (GH) Regulatory Elements for ZNF502 Gene

Promoters and enhancers for ZNF502 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF502 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF502

Top Transcription factor binding sites by QIAGEN in the ZNF502 gene promoter:
  • FOXD3
  • Ik-3
  • Nkx3-1
  • Nkx3-1 v1
  • Nkx3-1 v2
  • Nkx3-1 v3
  • Nkx3-1 v4
  • Sox9
  • TBP
  • TFIID

Genomic Locations for ZNF502 Gene

Genomic Locations for ZNF502 Gene
chr3:44,712,643-44,723,831
(GRCh38/hg38)
Size:
11,189 bases
Orientation:
Plus strand
chr3:44,754,135-44,765,323
(GRCh37/hg19)
Size:
11,189 bases
Orientation:
Plus strand

Genomic View for ZNF502 Gene

Genes around ZNF502 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF502 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF502 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF502 Gene

Proteins for ZNF502 Gene

  • Protein details for ZNF502 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TBZ5-ZN502_HUMAN
    Recommended name:
    Zinc finger protein 502
    Protein Accession:
    Q8TBZ5

    Protein attributes for ZNF502 Gene

    Size:
    544 amino acids
    Molecular mass:
    62920 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF502 Gene

Post-translational modifications for ZNF502 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF502 Gene

No data available for DME Specific Peptides for ZNF502 Gene

Domains & Families for ZNF502 Gene

Gene Families for ZNF502 Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF502 Gene

Blocks:
  • C2H2-type zinc finger signature
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF502 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 502 (ZN502_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8TBZ5

UniProtKB/Swiss-Prot:

ZN502_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF502: view

Function for ZNF502 Gene

Molecular function for ZNF502 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF502 Gene

Gene Ontology (GO) - Molecular Function for ZNF502 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF502: view
genes like me logo Genes that share phenotypes with ZNF502: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF502 Gene

Localization for ZNF502 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF502 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF502 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF502 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 25556234
genes like me logo Genes that share ontologies with ZNF502: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF502 Gene

Pathways & Interactions for ZNF502 Gene

PathCards logo

SuperPathways for ZNF502 Gene

No Data Available

Interacting Proteins for ZNF502 Gene

;

Gene Ontology (GO) - Biological Process for ZNF502 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044791 positive regulation by host of viral release from host cell IMP 25556234
GO:0044794 positive regulation by host of viral process IMP 25556234
genes like me logo Genes that share ontologies with ZNF502: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF502 Gene

Drugs & Compounds for ZNF502 Gene

No Compound Related Data Available

Transcripts for ZNF502 Gene

mRNA/cDNA for ZNF502 Gene

5 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF502 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d · 5e
SP1:
SP2: -
SP3: -
SP4: - -
SP5: - -

Relevant External Links for ZNF502 Gene

GeneLoc Exon Structure for
ZNF502

Expression for ZNF502 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF502 Gene

Protein differential expression in normal tissues from HIPED for ZNF502 Gene

This gene is overexpressed in Fetal testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF502 Gene



Protein tissue co-expression partners for ZNF502 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF502

SOURCE GeneReport for Unigene cluster for ZNF502 Gene:

Hs.224843
genes like me logo Genes that share expression patterns with ZNF502: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF502 Gene

Orthologs for ZNF502 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF502 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF502 31 30
  • 99.45 (n)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF502 31 30
  • 91.68 (n)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF502 31 30
  • 90.66 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100911237 30
  • 67.03 (n)
mouse
(Mus musculus)
Mammalia Zfp72 17 30
  • 65.42 (n)
oppossum
(Monodelphis domestica)
Mammalia ZNF502 31
  • 63 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 31
  • 49 (a)
OneToMany
Species where no ortholog for ZNF502 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF502 Gene

ENSEMBL:
Gene Tree for ZNF502 (if available)
TreeFam:
Gene Tree for ZNF502 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF502: view image

Paralogs for ZNF502 Gene

Paralogs for ZNF502 Gene

(471) SIMAP similar genes for ZNF502 Gene using alignment to 2 proteins:

  • ZN502_HUMAN
  • C9JLT3_HUMAN
genes like me logo Genes that share paralogs with ZNF502: view

Variants for ZNF502 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF502 Gene

SNP ID Clinical significance and condition Chr 03 pos Variation AA Info Type
rs56084453 - p.Gln174Arg
rs6798400 - p.Leu28Pro
rs7640654 - p.Glu243Ala

Additional dbSNP identifiers (rs#s) for ZNF502 Gene

Variation tolerance for ZNF502 Gene

Residual Variation Intolerance Score: 50.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.95; 74.58% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF502 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF502

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF502 Gene

Disorders for ZNF502 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF502 Gene - From: DISEASES

Disorder Aliases PubMed IDs
seminal vesicle tumor
  • seminal vesicle neoplasm
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for ZNF502

genes like me logo Genes that share disorders with ZNF502: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF502 Gene

Publications for ZNF502 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  2. The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. (PMID: 29180619) Kumar R … Vertegaal ACO (Nature communications 2017) 3 54
  3. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 54
  4. New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein. (PMID: 25556234) Kipper S … Bajorek M (Molecular & cellular proteomics : MCP 2015) 3 54
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 54

Products for ZNF502 Gene

Sources for ZNF502 Gene