Aliases for ZNF473 Gene
External Ids for ZNF473 Gene
Previous GeneCards Identifiers for ZNF473 Gene
This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein, a component of the U7 snRNP complex, plays a role in histone 3'-end pre-mRNA processing and may be required for cell cycle progression to S phase. Expression level and methylation status of this gene may be correlated with bone mineral density. [provided by RefSeq, Jul 2016]
GeneCards Summary for ZNF473 Gene
ZNF473 (Zinc Finger Protein 473) is a Protein Coding gene. Diseases associated with ZNF473 include Cervical Adenosquamous Carcinoma and Epithelial Recurrent Erosion Dystrophy. Among its related pathways are Gene Expression and Cleavage of Growing Transcript in the Termination Region. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF91.
UniProtKB/Swiss-Prot Summary for ZNF473 Gene
Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.