Aliases for ZNF473 Gene
External Ids for ZNF473 Gene
Previous GeneCards Identifiers for ZNF473 Gene
This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein, a component of the U7 snRNP complex, plays a role in histone 3'-end pre-mRNA processing and may be required for cell cycle progression to S phase. Expression level and methylation status of this gene may be correlated with bone mineral density. [provided by RefSeq, Jul 2016]
GeneCards Summary for ZNF473 Gene
ZNF473 (Zinc Finger Protein 473) is a Protein Coding gene. Diseases associated with ZNF473 include Cervical Adenosquamous Carcinoma. Among its related pathways are Processing of Capped Intronless Pre-mRNA and Tat-mediated elongation of the HIV-1 transcript. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF184.
UniProtKB/Swiss-Prot Summary for ZNF473 Gene
Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.