Aliases for ZNF467 Gene
External Ids for ZNF467 Gene
Previous GeneCards Identifiers for ZNF467 Gene
The protein encoded by this gene is a zinc finger protein whose function has not yet been elucidated in humans. However, the mouse ortholog of this protein enhances adipocyte differentiation and suppresses osteoblast differentiation in bone marrow. The mouse protein also is a transcription factor for several genes and can help recruit histone deacetylase complexes. [provided by RefSeq, Aug 2016]
GeneCards Summary for ZNF467 Gene
ZNF467 (Zinc Finger Protein 467) is a Protein Coding gene. Diseases associated with ZNF467 include Pericoronitis and Mixed Malaria. Among its related pathways are Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) and Developmental Biology. An important paralog of this gene is ZNF572.
UniProtKB/Swiss-Prot Summary for ZNF467 Gene
Transcription factor that promotes adipocyte differentiation and suppresses osteoblast differentiation in the bone marrow. Enhances the osteoclast-supporting ability of stromal cells. Binds with STAT3 the consensus sequence 5'-CTTCTGGGAAGA-3' of the acute phase response element (APRE). Transactivates several promoters including FOS, OSM and PPARG. Recruits a histone deacetylase complex (By similarity).