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ZNF451 (Zinc Finger Protein 451) is a Protein Coding gene. Diseases associated with ZNF451 include Motion Sickness and Brown-Sequard Syndrome. An important paralog of this gene is PRDM1.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003676 | nucleic acid binding | IEA | -- |
GO:0003714 | transcription corepressor activity | IMP | 24324267 |
GO:0005515 | protein binding | IPI | 16189514 |
GO:0016740 | transferase activity | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IBA,IDA | 24324267 |
GO:0005654 | nucleoplasm | IEA | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO:0016605 | PML body | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0010468 | regulation of gene expression | IBA | 21873635 |
GO:0016925 | protein sumoylation | IEA | -- |
GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | IMP | 24324267 |
GO:0060633 | negative regulation of transcription initiation from RNA polymerase II promoter | IMP | 24324267 |
GO:2000616 | negative regulation of histone H3-K9 acetylation | IMP | 24324267 |
ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
SP3: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
SP4: | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP5: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
SP6: |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ZNF451 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | ZNF451 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | ZNF451 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Zfp451 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Zfp451 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Oppossum (Monodelphis domestica) |
Mammalia | ZNF451 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | ZNF451 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | ZNF451 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | znf451 30 |
|
||
Str.3549 30 |
|
||||
Zebrafish (Danio rerio) |
Actinopterygii | znf451 30 31 |
|
OneToOne |
Disorder | Aliases | PubMed IDs |
---|---|---|
motion sickness |
|
|
brown-sequard syndrome |
|
|
peroneal neuropathy |
|
|