Aliases for ZNF429 Gene

Aliases for ZNF429 Gene

  • Zinc Finger Protein 429 2 3 4 5
  • ZNF429 5

External Ids for ZNF429 Gene

Previous GeneCards Identifiers for ZNF429 Gene

  • GC19U900125
  • GC19P021480
  • GC19P021688
  • GC19P021178

Summaries for ZNF429 Gene

GeneCards Summary for ZNF429 Gene

ZNF429 (Zinc Finger Protein 429) is a Protein Coding gene. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF254.

UniProtKB/Swiss-Prot Summary for ZNF429 Gene

Additional gene information for ZNF429 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF429 Gene

Genomics for ZNF429 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF429 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF429 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for ZNF429 Gene

Genomic Locations for ZNF429 Gene
chr19:21,496,682-21,556,270
(GRCh38/hg38)
Size:
59,589 bases
Orientation:
Plus strand
chr19:21,679,484-21,739,072
(GRCh37/hg19)
Size:
59,589 bases
Orientation:
Plus strand

Genomic View for ZNF429 Gene

Genes around ZNF429 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF429 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF429 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF429 Gene

Proteins for ZNF429 Gene

  • Protein details for ZNF429 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86V71-ZN429_HUMAN
    Recommended name:
    Zinc finger protein 429
    Protein Accession:
    Q86V71
    Secondary Accessions:
    • A6NLV7
    • Q9BZE6

    Protein attributes for ZNF429 Gene

    Size:
    674 amino acids
    Molecular mass:
    78152 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAK01422.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=AAK01422.1; Type=Miscellaneous discrepancy; Evidence={ECO:0000305}; Sequence=AAP30884.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=AAP30884.1; Type=Miscellaneous discrepancy; Evidence={ECO:0000305};

neXtProt entry for ZNF429 Gene

Post-translational modifications for ZNF429 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF429 Gene

Domains & Families for ZNF429 Gene

Gene Families for ZNF429 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF429 Gene

InterPro:
Blocks:
  • KRAB box
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF429 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 429 (ZN429_HUMAN)
genes like me logo Genes that share domains with ZNF429: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ZNF429 Gene

Function for ZNF429 Gene

Molecular function for ZNF429 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF429 Gene

Gene Ontology (GO) - Molecular Function for ZNF429 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF429: view
genes like me logo Genes that share phenotypes with ZNF429: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF429

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF429 Gene

Localization for ZNF429 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF429 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF429 gene
Compartment Confidence
nucleus 4
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF429 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF429: view

Pathways & Interactions for ZNF429 Gene

genes like me logo Genes that share pathways with ZNF429: view

Pathways by source for ZNF429 Gene

2 Reactome pathways for ZNF429 Gene
1 KEGG pathway for ZNF429 Gene

Interacting Proteins for ZNF429 Gene

Gene Ontology (GO) - Biological Process for ZNF429 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF429: view

No data available for SIGNOR curated interactions for ZNF429 Gene

Drugs & Compounds for ZNF429 Gene

No Compound Related Data Available

Transcripts for ZNF429 Gene

mRNA/cDNA for ZNF429 Gene

6 REFSEQ mRNAs :
6 NCBI additional mRNA sequence :
9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF429

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF429 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c
SP1: - -
SP2: - - -
SP3: - - -
SP4: - - - -
SP5:

Relevant External Links for ZNF429 Gene

GeneLoc Exon Structure for
ZNF429

Expression for ZNF429 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF429 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF429

SOURCE GeneReport for Unigene cluster for ZNF429 Gene:

Hs.572567
genes like me logo Genes that share expression patterns with ZNF429: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF429 Gene

Orthologs for ZNF429 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF429 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ZNF429 31
  • 68 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia -- 31
  • 55 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 53 (a)
ManyToMany
-- 31
  • 43 (a)
ManyToMany
Mouse
(Mus musculus)
Mammalia Rslcan18 31
  • 45 (a)
ManyToMany
Dog
(Canis familiaris)
Mammalia -- 31
  • 40 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 55 (a)
ManyToMany
-- 31
  • 48 (a)
ManyToMany
-- 31
  • 43 (a)
ManyToMany
-- 31
  • 40 (a)
ManyToMany
-- 31
  • 37 (a)
ManyToMany
-- 31
  • 37 (a)
ManyToMany
-- 31
  • 36 (a)
ManyToMany
-- 31
  • 31 (a)
ManyToMany
Species where no ortholog for ZNF429 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ZNF429 Gene

ENSEMBL:
Gene Tree for ZNF429 (if available)
TreeFam:
Gene Tree for ZNF429 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF429: view image

Paralogs for ZNF429 Gene

Paralogs for ZNF429 Gene

(564) SIMAP similar genes for ZNF429 Gene using alignment to 3 proteins:

  • ZN429_HUMAN
  • M0QYC4_HUMAN
  • M0QZ47_HUMAN

Pseudogenes.org Pseudogenes for ZNF429 Gene

genes like me logo Genes that share paralogs with ZNF429: view

Variants for ZNF429 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF429 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs2562473 - p.His650Tyr

Additional dbSNP identifiers (rs#s) for ZNF429 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF429 Gene

Variant ID Type Subtype PubMed ID
esv1010333 CNV insertion 20482838
esv2667083 CNV deletion 23128226
esv2718325 CNV deletion 23290073
esv2718335 CNV deletion 23290073
esv2718336 CNV deletion 23290073
esv2751783 CNV loss 17911159
esv2762028 CNV gain 21179565
esv3556176 CNV deletion 23714750
esv4924 OTHER complex 18987735
esv6839 CNV loss 19470904
nsv1061327 CNV gain 25217958
nsv1109177 CNV deletion 24896259
nsv1123235 CNV deletion 24896259
nsv458377 CNV gain 19166990
nsv510759 CNV deletion 20534489
nsv578809 CNV gain 21841781
nsv578952 CNV gain 21841781
nsv833782 CNV loss 17160897
nsv954636 CNV deletion 24416366
nsv963024 CNV duplication 23825009

Variation tolerance for ZNF429 Gene

Residual Variation Intolerance Score: 88.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.46; 54.91% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF429 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF429

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF429 Gene

Disorders for ZNF429 Gene

Additional Disease Information for ZNF429

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform

No disorders were found for ZNF429 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF429 Gene

Publications for ZNF429 Gene

  1. Genome-wide association study of acute post-surgical pain in humans. (PMID: 19207018) Kim H … Dionne RA (Pharmacogenomics 2009) 3 41
  2. Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937. (PMID: 7865130) Abrink M … Hellman L (DNA and cell biology 1995) 3 4
  3. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PMID: 17903293) Benjamin EJ … Vasan RS (BMC medical genetics 2007) 41
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4

Products for ZNF429 Gene

Sources for ZNF429 Gene