Aliases for ZNF426 Gene
External Ids for ZNF426 Gene
Previous GeneCards Identifiers for ZNF426 Gene
Kaposi's sarcoma-associated herpesvirus (KSHV) can be reactivated from latency by the viral protein RTA. The protein encoded by this gene is a zinc finger transcriptional repressor that interacts with RTA to modulate RTA-mediated reactivation of KSHV. While the encoded protein can repress KSHV reactivation, RTA can induce degradation of this protein through the ubiquitin-proteasome pathway to overcome the repression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
GeneCards Summary for ZNF426 Gene
ZNF426 (Zinc Finger Protein 426) is a Protein Coding gene. Diseases associated with ZNF426 include Kaposi Sarcoma. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF266.
UniProtKB/Swiss-Prot for ZNF426 Gene
May be involved in transcriptional regulation.