Aliases for ZNF426 Gene
External Ids for ZNF426 Gene
Previous GeneCards Identifiers for ZNF426 Gene
Kaposi's sarcoma-associated herpesvirus (KSHV) can be reactivated from latency by the viral protein RTA. The protein encoded by this gene is a zinc finger transcriptional repressor that interacts with RTA to modulate RTA-mediated reactivation of KSHV. While the encoded protein can repress KSHV reactivation, RTA can induce degradation of this protein through the ubiquitin-proteasome pathway to overcome the repression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
GeneCards Summary for ZNF426 Gene
ZNF426 (Zinc Finger Protein 426) is a Protein Coding gene. Diseases associated with ZNF426 include Kaposi Sarcoma. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF287.
UniProtKB/Swiss-Prot Summary for ZNF426 Gene
May be involved in transcriptional regulation.