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Aliases for ZNF417 Gene

Aliases for ZNF417 Gene

  • Zinc Finger Protein 417 2 3 5

External Ids for ZNF417 Gene

Previous GeneCards Identifiers for ZNF417 Gene

  • GC00U900990
  • GC19M063111
  • GC19M058417
  • GC19M054728

Summaries for ZNF417 Gene

GeneCards Summary for ZNF417 Gene

ZNF417 (Zinc Finger Protein 417) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF587.

UniProtKB/Swiss-Prot for ZNF417 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF417 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF417 Gene

Genomics for ZNF417 Gene

GeneHancer (GH) Regulatory Elements for ZNF417 Gene

Promoters and enhancers for ZNF417 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I057914 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 575.6 +0.9 855 3.3 PKNOX1 FOXA2 MLX ARID4B SIN3A FEZF1 DMAP1 ZBTB7B YY1 POLR2B ZNF417 ENSG00000269476 TRIM28 ZNF264 LOC100128398 ZNF805 ZNF587 ENSG00000269867 ZNF586 ZNF274
GH19I058181 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 89.2 -266.6 -266620 2.5 HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 ZNF274 ZNF134 ZNF606 ZNF17 ZNF417 ZNF549 ZNF550 ZNF773 LOC105372483 ZNF264
GH19I058325 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 78.8 -410.3 -410255 3.6 CLOCK ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF416 ZSCAN22 LOC105372480 PIR44424 ZNF134 ZNF606 ZNF417 ZNF549 ZNF135 ZNF17 ZNF446
GH19I058553 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 58.6 -640.5 -640497 7.2 CLOCK FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 CHMP2A UBE2M TRIM28 ZNF417 ZNF134 ZNF606 ZNF274 MZF1 LOC100128398 ERVK3-1
GH19I057599 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 59.6 +316.6 316579 1.5 PKNOX1 SMAD1 ARID4B SIN3A DMAP1 YY1 E2F8 ZNF207 ZNF143 KLF13 ZNF530 ZNF606 ZNF549 ZNF135 ZNF417 ZNF132 ZNF418 ZNF446 ZNF17 LOC105372482
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF417 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF417 Gene

Genomic Locations for ZNF417 Gene
chr19:57,900,296-57,916,616
(GRCh38/hg38)
Size:
16,321 bases
Orientation:
Minus strand
chr19:58,411,664-58,427,978
(GRCh37/hg19)

Genomic View for ZNF417 Gene

Genes around ZNF417 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF417 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF417 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF417 Gene

Proteins for ZNF417 Gene

  • Protein details for ZNF417 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TAU3-ZN417_HUMAN
    Recommended name:
    Zinc finger protein 417
    Protein Accession:
    Q8TAU3
    Secondary Accessions:
    • B4DEU1

    Protein attributes for ZNF417 Gene

    Size:
    575 amino acids
    Molecular mass:
    65733 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF417 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF417 Gene

Post-translational modifications for ZNF417 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF417 Gene

Domains & Families for ZNF417 Gene

Gene Families for ZNF417 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for ZNF417 Gene

Graphical View of Domain Structure for InterPro Entry

Q8TAU3

UniProtKB/Swiss-Prot:

ZN417_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF417: view

Function for ZNF417 Gene

Molecular function for ZNF417 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF417 Gene

Gene Ontology (GO) - Molecular Function for ZNF417 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 16189514
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF417: view
genes like me logo Genes that share phenotypes with ZNF417: view

miRNA for ZNF417 Gene

miRTarBase miRNAs that target ZNF417

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF417 Gene

Localization for ZNF417 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF417 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF417 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF417 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF417: view

Pathways & Interactions for ZNF417 Gene

SuperPathways for ZNF417 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF417: view

Pathways by source for ZNF417 Gene

2 Reactome pathways for ZNF417 Gene

Gene Ontology (GO) - Biological Process for ZNF417 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF417: view

No data available for SIGNOR curated interactions for ZNF417 Gene

Drugs & Compounds for ZNF417 Gene

No Compound Related Data Available

Transcripts for ZNF417 Gene

Unigene Clusters for ZNF417 Gene

Zinc finger protein 417:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF417 Gene

No ASD Table

Relevant External Links for ZNF417 Gene

GeneLoc Exon Structure for
ZNF417
ECgene alternative splicing isoforms for
ZNF417

Expression for ZNF417 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF417 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF417 Gene



NURSA nuclear receptor signaling pathways regulating expression of ZNF417 Gene:

ZNF417

SOURCE GeneReport for Unigene cluster for ZNF417 Gene:

Hs.567710

Evidence on tissue expression from TISSUES for ZNF417 Gene

  • Nervous system(4.3)
  • Pancreas(4.1)
genes like me logo Genes that share expression patterns with ZNF417: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF417 Gene

Orthologs for ZNF417 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF417 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 34
  • 98 (a)
ManyToMany
-- 34
  • 96 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 34
  • 52 (a)
OneToMany
Species where no ortholog for ZNF417 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF417 Gene

ENSEMBL:
Gene Tree for ZNF417 (if available)
TreeFam:
Gene Tree for ZNF417 (if available)

Paralogs for ZNF417 Gene

(535) SIMAP similar genes for ZNF417 Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with ZNF417: view

Variants for ZNF417 Gene

Sequence variations from dbSNP and Humsavar for ZNF417 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000070826 -- 57,917,743(-) G/C upstream_transcript_variant
rs1000513626 -- 57,917,953(-) T/C upstream_transcript_variant
rs1000751349 -- 57,908,465(-) C/G 3_prime_UTR_variant
rs1001311378 -- 57,917,453(-) C/T upstream_transcript_variant
rs1001800470 -- 57,913,610(-) G/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF417 Gene

Variant ID Type Subtype PubMed ID
esv2719094 CNV deletion 23290073
esv3644913 CNV gain 21293372
esv3893258 CNV gain 25118596
nsv1066059 CNV gain 25217958
nsv963085 CNV duplication 23825009

Variation tolerance for ZNF417 Gene

Residual Variation Intolerance Score: 90.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.69; 66.02% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF417 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF417

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF417 Gene

Disorders for ZNF417 Gene

Additional Disease Information for ZNF417

No disorders were found for ZNF417 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF417 Gene

Publications for ZNF417 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  2. Widespread macromolecular interaction perturbations in human genetic disorders. (PMID: 25910212) Sahni N … Vidal M (Cell 2015) 3 58
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  4. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H … Vidal M (Nature methods 2011) 3 58
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual JF … Vidal M (Nature 2005) 3 58

Products for ZNF417 Gene

Sources for ZNF417 Gene