Aliases for ZNF397 Gene
External Ids for ZNF397 Gene
Previous HGNC Symbols for ZNF397 Gene
Previous GeneCards Identifiers for ZNF397 Gene
This gene encodes a protein with a N-terminal SCAN domain, and the longer isoform contains nine C2H2-type zinc finger repeats in the C-terminal domain. The protein localizes to centromeres during interphase and early prophase, and different isoforms can repress or activate transcription in transfection studies. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but their biological validity has not been determined. [provided by RefSeq, Oct 2009]
GeneCards Summary for ZNF397 Gene
ZNF397 (Zinc Finger Protein 397) is a Protein Coding gene. Diseases associated with ZNF397 include Gastric Antral Vascular Ectasia. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is ZKSCAN8.
UniProtKB/Swiss-Prot Summary for ZNF397 Gene
Isoform 3 acts as a DNA-dependent transcriptional repressor.