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Aliases for ZNF385C Gene

Aliases for ZNF385C Gene

  • Zinc Finger Protein 385C 2 3 5
  • CTD-2132N18.2 3
  • CTD-2132N18.4 3

External Ids for ZNF385C Gene

Previous GeneCards Identifiers for ZNF385C Gene

  • GC17M037432
  • GC17M040177
  • GC17M035942

Summaries for ZNF385C Gene

GeneCards Summary for ZNF385C Gene

ZNF385C (Zinc Finger Protein 385C) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF385D.

Additional gene information for ZNF385C Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF385C Gene

Genomics for ZNF385C Gene

GeneHancer (GH) Regulatory Elements for ZNF385C Gene

Promoters and enhancers for ZNF385C Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I042097 Enhancer 0.8 Ensembl ENCODE 550.8 +0.0 25 1.6 L3MBTL2 ZBTB8A TEAD3 ZNF335 ZNF366 GLIS1 ZFP36 PRDM10 EZH2 ZNF385C CNP KCNH4 HCRT KLHL11 DHX58 C17orf113
GH17I042015 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10.7 +81.2 81175 2.9 HDGF PKNOX1 SMAD1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B DNAJC7 NKIRAS2 ENSG00000267758 CNTNAP1 ENSG00000259623 STAT5A NAGLU NT5C3B TUBG2 RETREG3
GH17I041965 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 10.7 +131.6 131581 3.5 HDGF PKNOX1 ZFP64 ARID4B SIN3A DMAP1 YY1 ZNF207 ZNF143 SP3 CNP GC17P041968 GC17P041973 PIR42788 NT5C3B ENSG00000267758 NKIRAS2 DNAJC7 ZNF385C DHX58
GH17I042022 Enhancer 1.4 Ensembl ENCODE dbSUPER 11.7 +74.1 74126 3.6 HDGF PKNOX1 ARNT ARID4B SIN3A ZNF2 POLR2B ZNF766 ZNF143 FOS PIR51799 NT5C3B PLEKHH3 DHX58 ZNF385C CNP ACLY DNAJC7 NKIRAS2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF385C on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF385C gene promoter:

Genomic Locations for ZNF385C Gene

Genomic Locations for ZNF385C Gene
73,604 bases
Minus strand

Genomic View for ZNF385C Gene

Genes around ZNF385C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF385C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF385C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF385C Gene

Proteins for ZNF385C Gene

  • Protein details for ZNF385C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 385C
    Protein Accession:
    Secondary Accessions:
    • Q4G0J1

    Protein attributes for ZNF385C Gene

    422 amino acids
    Molecular mass:
    44107 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF385C Gene


neXtProt entry for ZNF385C Gene

Post-translational modifications for ZNF385C Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZNF385C Gene

Domains & Families for ZNF385C Gene

Gene Families for ZNF385C Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for ZNF385C Gene

Suggested Antigen Peptide Sequences for ZNF385C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZNF385C: view

No data available for UniProtKB/Swiss-Prot for ZNF385C Gene

Function for ZNF385C Gene

Phenotypes From GWAS Catalog for ZNF385C Gene

Gene Ontology (GO) - Molecular Function for ZNF385C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002039 p53 binding IBA --
GO:0003723 RNA binding IBA --
GO:0005515 protein binding IPI 25416956
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF385C: view

Phenotypes for ZNF385C Gene

GenomeRNAi human phenotypes for ZNF385C:
genes like me logo Genes that share phenotypes with ZNF385C: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF385C Gene

Localization for ZNF385C Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF385C Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF385C gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF385C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF385C: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF385C Gene

Pathways & Interactions for ZNF385C Gene

SuperPathways for ZNF385C Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF385C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator IBA --
genes like me logo Genes that share ontologies with ZNF385C: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF385C Gene

Drugs & Compounds for ZNF385C Gene

No Compound Related Data Available

Transcripts for ZNF385C Gene

Unigene Clusters for ZNF385C Gene

Zinc finger protein 385C:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF385C Gene

No ASD Table

Relevant External Links for ZNF385C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF385C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF385C Gene

mRNA differential expression in normal tissues according to GTEx for ZNF385C Gene

This gene is overexpressed in Testis (x9.5) and Brain - Cerebellum (x7.2).

Protein differential expression in normal tissues from HIPED for ZNF385C Gene

This gene is overexpressed in Breast (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF385C Gene

Protein tissue co-expression partners for ZNF385C Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF385C Gene:


SOURCE GeneReport for Unigene cluster for ZNF385C Gene:


Evidence on tissue expression from TISSUES for ZNF385C Gene

  • Nervous system(4)
genes like me logo Genes that share expression patterns with ZNF385C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF385C Gene

Orthologs for ZNF385C Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF385C Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF385C 34
  • 87 (a)
(Canis familiaris)
Mammalia ZNF385C 34
  • 82 (a)
(Bos Taurus)
Mammalia ZNF385C 34
  • 79 (a)
(Mus musculus)
Mammalia Zfp385c 34
  • 73 (a)
(Monodelphis domestica)
Mammalia ZNF385C 34
  • 68 (a)
(Ornithorhynchus anatinus)
Mammalia ZNF385C 34
  • 47 (a)
(Gallus gallus)
Aves ZNF385C 34
  • 52 (a)
(Anolis carolinensis)
Reptilia ZNF385C 34
  • 50 (a)
(Danio rerio)
Actinopterygii znf385c 34
  • 40 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 17 (a)
Species where no ortholog for ZNF385C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF385C Gene

Gene Tree for ZNF385C (if available)
Gene Tree for ZNF385C (if available)

Paralogs for ZNF385C Gene

Paralogs for ZNF385C Gene

(4) SIMAP similar genes for ZNF385C Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF385C: view

Variants for ZNF385C Gene

Sequence variations from dbSNP and Humsavar for ZNF385C Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000074571 -- 42,039,517(-) G/A 3_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000145914 -- 42,053,922(-) G/C 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant
rs1000351650 -- 42,032,724(-) T/C genic_downstream_transcript_variant, intron_variant
rs1000420097 -- 42,046,801(-) C/G genic_upstream_transcript_variant, intron_variant
rs1000479070 -- 42,052,520(-) T/A genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF385C Gene

Variant ID Type Subtype PubMed ID
nsv1146669 OTHER inversion 26484159
nsv1056904 CNV gain 25217958

Variation tolerance for ZNF385C Gene

Gene Damage Index Score: 1.71; 32.62% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF385C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF385C Gene

Disorders for ZNF385C Gene

Additional Disease Information for ZNF385C

No disorders were found for ZNF385C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF385C Gene

Publications for ZNF385C Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  2. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H … Vidal M (Nature methods 2011) 3 58
  3. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4 58
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R … Stanton LW (Nature biotechnology 2004) 3 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for ZNF385C Gene

Sources for ZNF385C Gene

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