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Aliases for ZNF350 Gene
Aliases for ZNF350 Gene
External Ids for ZNF350 Gene
- HGNC: 16656
- NCBI Entrez Gene: 59348
- Ensembl: ENSG00000256683
- OMIM®: 605422
- UniProtKB/Swiss-Prot: Q9GZX5
Previous GeneCards Identifiers for ZNF350 Gene
- GC19M057143
- GC19M057159
- GC19M052468
- GC19M052470
Summaries for ZNF350 Gene
GeneCards Summary for ZNF350 Gene
ZNF350 (Zinc Finger Protein 350) is a Protein Coding gene. Diseases associated with ZNF350 include Breast Medullary Carcinoma and Benign Breast Phyllodes Tumor. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding. An important paralog of this gene is ZNF613.
UniProtKB/Swiss-Prot Summary for ZNF350 Gene
-
Transcriptional repressor. Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3.
Additional gene information for ZNF350 Gene
- HGNC (16656)
- NCBI Entrez Gene (59348)
- Ensembl (ENSG00000256683)
- OMIM® (605422)
- UniProtKB/Swiss-Prot (Q9GZX5)
- Open Targets Platform(ENSG00000256683)
- Search for ZNF350 at DataMed
- Search for ZNF350 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF350 Gene
Genomics for ZNF350 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ZNF350 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ZNF350 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF350
- Top Transcription factor binding sites by QIAGEN in the ZNF350 gene promoter:
-
- Bach1
- FOXL1
Genomic Locations for ZNF350 Gene
Latest Assembly
- chr19:51,964,340-51,986,856
- (GRCh38/hg38)
- Size:
- 22,517 bases
- Orientation:
- Minus strand
Previous Assembly
- chr19:52,467,593-52,490,093
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 22,501 bases
- Orientation:
- Minus strand
- chr19:52,467,596-52,490,109
- (GRCh37/hg19 by Ensembl)
- Size:
- 22,514 bases
- Orientation:
- Minus strand
Genomic View for ZNF350 Gene
Genes around ZNF350 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.41 by HGNC
- 19q13.41 by Entrez Gene
- 19q13.41 by Ensembl
ZNF350 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZNF350 Gene
Proteins for ZNF350 Gene
-
Protein details for ZNF350 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9GZX5-ZN350_HUMAN
- Recommended name:
- Zinc finger protein 350
- Protein Accession:
- Q9GZX5
- Q96G73
- Q9HAQ4
Protein attributes for ZNF350 Gene
- Size:
- 532 amino acids
- Molecular mass:
- 60011 Da
- Quaternary structure:
-
- Interacts with BRCA1. Interacts with RNF11.
Post-translational modifications for ZNF350 Gene
Other Protein References for ZNF350 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
-
Custom Antibody ServicesOriGene Antibodies for ZNF350
- Novus Biologicals Antibodies for ZNF350
- Invitrogen Antibodies for ZNF350 (AFLGC-ZNF350)
-
Boster Bio Antibodies for ZNF350
-
Custom Antibody ServicesProSci Antibodies for ZNF350
Protein products for research
-
OriGene Purified Proteins for ZNF350
- Search Origene for MassSpec and Protein Over-expression Lysates for ZNF350
- Origene Custom Protein Services for ZNF350
-
Abcam proteins for ZNF350
Assay products for research
No data available for DME Specific Peptides for ZNF350 Gene
Domains & Families for ZNF350 Gene
Gene Families for ZNF350 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZNF350 Gene
- InterPro:
- Blocks:
-
- KRAB box
- ProtoNet:
Suggested Antigen Peptide Sequences for ZNF350 Gene
- GenScript: Design optimal peptide antigens:
-
- Zinc finger protein ZBRK1 (ZN350_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9GZX5- Family:
-
- Belongs to the krueppel C2H2-type zinc-finger protein family.
Function for ZNF350 Gene
Molecular function for ZNF350 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional repressor. Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3.
Phenotypes From GWAS Catalog for ZNF350 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IBA | 21873635 |
| GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding | IDA | 11090615 |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific | IDA | 11090615 |
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | IEA,IDA | 11090615 |
Phenotypes for ZNF350 Gene
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ZNF350 - Starting at $85 >
- * ZNF350 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ZNF350
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF350
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF350
miRNA for ZNF350 Gene
- miRTarBase miRNAs that target ZNF350
-
- hsa-miR-181a-5p (MIRT025098)
- hsa-miR-642a-3p (MIRT348730)
- hsa-miR-642b-3p (MIRT348737)
- hsa-miR-4789-3p (MIRT348739)
- hsa-miR-4433b-5p (MIRT574262)
- hsa-miR-188-3p (MIRT574263)
- hsa-miR-582-5p (MIRT574264)
- hsa-miR-101-3p (MIRT574265)
- hsa-miR-4669 (MIRT574266)
- hsa-miR-3657 (MIRT574267)
- hsa-miR-4433a-5p (MIRT574268)
- hsa-miR-885-5p (MIRT574269)
- hsa-miR-6504-3p (MIRT574270)
- hsa-miR-511-3p (MIRT574271)
- hsa-miR-5580-3p (MIRT574272)
- hsa-miR-6512-5p (MIRT574273)
- hsa-miR-144-3p (MIRT574274)
- hsa-miR-21-3p (MIRT735366)
- hsa-miR-150-5p (MIRT735367)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF350
- Browse OriGene Inhibitory RNA Products For ZNF350
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF350
Clone products for research
- Applied Biological Materials (abm): Clones for ZNF350 - Starting at $45 >
- * ZNF350 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ZNF350
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF350
Cell Lines for research
-
Horizon Cell Lines for ZNF350
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF350 Gene
Localization for ZNF350 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZNF350 Gene
- Nucleus. Nucleus matrix. Note=Associated with the nuclear matrix.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 1 |
| cytoskeleton | 1 |
- Nuclear bodies (3)
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000785 | chromatin | IBA | -- |
| GO:0005634 | nucleus | IEA,IDA | 23665872 |
| GO:0005654 | nucleoplasm | IDA,TAS | -- |
| GO:0016363 | nuclear matrix | IEA | -- |
| GO:0016604 | nuclear body | IDA | -- |
Pathways & Interactions for ZNF350 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Gene Expression |
.48
|
|
| 2 | Herpes simplex virus 1 infection | ||
Pathways by source for ZNF350 Gene
2 Reactome pathways for ZNF350 Gene
1 KEGG pathway for ZNF350 Gene
Interacting Proteins for ZNF350 Gene
Selected Interacting proteins:
Q9GZX5-ZN350_HUMAN
ENSP00000243644
for ZNF350 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for ZNF350
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IDA | 11090615 |
| GO:0006355 | regulation of transcription, DNA-templated | IEA,IDA | 11090615 |
| GO:0006357 | regulation of transcription by RNA polymerase II | IBA | 21873635 |
| GO:0045892 | negative regulation of transcription, DNA-templated | IDA | 11090615 |
No data available for SIGNOR curated interactions for ZNF350 Gene
Transcripts for ZNF350 Gene
mRNA/cDNA for ZNF350 Gene
- 1 REFSEQ mRNAs :
- 7 NCBI additional mRNA sequence :
- 9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000243644 2355 nts (view in UCSC)
- ENST00000593596 489 nts (view in UCSC)
- ENST00000594929 553 nts (view in UCSC)
- ENST00000597555 1601 nts (view in UCSC)
- ENST00000597788 533 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ZNF350 - Starting at $85 >
- * ZNF350 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ZNF350
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF350
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF350
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF350
- Browse OriGene Inhibitory RNA Products For ZNF350
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF350
Clone products for research
- Applied Biological Materials (abm): Clones for ZNF350 - Starting at $45 >
- * ZNF350 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ZNF350
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF350
Relevant External Links for ZNF350 Gene
- GeneLoc Exon Structure for
- ZNF350
Expression for ZNF350 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
- Hematopoietic Bone Marrow
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF350
SOURCE GeneReport for Unigene cluster for ZNF350 Gene:
Hs.407694mRNA Expression by UniProt/SwissProt for ZNF350 Gene:
Q9GZX5-ZN350_HUMAN
Tissue specificity:
Widely expressed.
Evidence on tissue expression from TISSUES for ZNF350 Gene
- Kidney(4.2)
Primer products for research
-
OriGene qPCR primer pairs for ZNF350
-
OriGene qPCR primer pairs and template standards for ZNF350
Gene Expression Assays for research
No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF350 Gene
Orthologs for ZNF350 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ZNF350 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | ZNF347 30 |
|
||
| -- 31 |
|
OneToMany | |||
| ZNF350 31 |
|
OneToMany | |||
| Dog (Canis familiaris) |
Mammalia | ZNF350 31 |
|
OneToOne |
- Species where no ortholog for ZNF350 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Mouse (Mus musculus)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for ZNF350 Gene
- ENSEMBL:
- Gene Tree for ZNF350 (if available)
- TreeFam:
- Gene Tree for ZNF350 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ZNF350: view image
Paralogs for ZNF350 Gene
Paralogs for ZNF350 Gene
(468) SIMAP similar genes for ZNF350 Gene using alignment to 5 proteins:
- ZN350_HUMAN
- M0QY52_HUMAN
- M0QYT6_HUMAN
- M0R017_HUMAN
- M0R1T8_HUMAN
- ZNF649
- ZNF615
- ZNF614
- FIK
- ZNF613
- ZNF432
- ZNF415
- ZFP90
- KRBOX4
- ZNF10
- ZNF559
- ZNF84
- ZNF420
- ZNF177
- ZNF169
- ZNF705A
- ZNF81
- ZNF793
- ZNF268
- ZNF585B
- ZNF814
- ZNF283
- ZNF300P1
- ZNF607
- ZNF577
- ZNF569
- ZNF669
- ZNF26
- ZSCAN16
- MGC12518
- ZNF624
- ZNF554
- ZNF317
- ZNF582
- ZNF208
- ZNF93
- ZNF546
- ZNF738
- ZNF674
- ZNF519
- ZNF551
- ZNF630
- ZFP41
- ZFP30
- ZNF625
- ZNF790
- ZNF140
- ZNF529
- ZNF78L1
- ZNF540
- ZNF850
- ZNF22
- ZNF114
- ZNF181
- ZNF461
- ZNF583
- ZNF229
- ZNF91
- ZNF274
- ZNF324B
- ZFP14
- ZNF726
- ZNF506
- ZNF675
- ZNF556
- ZNF124
- ZNF778
- ZNF175
- ZNF562
- ZNF248
- ZSCAN23
- ZNF561
- ZNF721
- LOC101928664
- ZNF439
- ZNF302
- ZNF250
- ZNF133
- ZNF419
- ZNF586
- ZNF684
- ZNF235
- ZNF780A
- ZNF573
- ZNF90
- ZNF707
- ZNF257
- ZNF354B
- ZNF776
- ZNF585A
- ZNF682
- ZNF527
- zf30
- ZNF780B
- ZNF267
- ZNF134
- GLI4
- ZNF763
- ZNF709
- ZNF846
- ZNF791
- ZNF138
- ZNF34
- ZNF720
- ZNF627
- ZNF471
- ZNF426
- ZNF66
- ZNF789
- ZNF616
- ZNF728
- ZNF354A
- ZNF596
- ZNF670
- ZNF724P
- ZNF320
- ZNF664
- ZNF595
- ZNF501
- ZNF383
- ZNF788
- ZNF226
- DKFZp666C237
- ZNF
- ZNF433
- ZNF101
- ZNF98
- ZNF655
- ZNF844
- ZNF565
- ZNF273
- ZNF879
- ZNF83
- ZNF33A
- ZNF300
- ZNF695
- ZNF493
- ZNF430
- ZSCAN29
- ZNF571
- ZNF566
- ZNF431
- ZNF397
- ZNF429
- ZNF225
- HZF36
- HZF30
- DKFZp686D2168
- ZNF322
- ZNF232
- ZNF331
- ZNF567
- ZNF443
- ZNF418
- ZNF85
- ZNF808
- ZNF470
- ZNF717
- ZNF7
- ZNF230
- ZNF878
- ZNF223
- ZNF19
- ZNF233
- ZNF224
- ZNF620
- ZNF195
- ZNF417
- ZSCAN9
- ZSCAN30
- ZNF696
- ZNF774
- DKFZp434J0650
- ZNF3
- ZNF286A
- ZNF718
- ZNF514
- ZNF845
- ZNF251
- ZNF737
- ZNF766
- ZNF227
- ZNF112
- ZNF761
- ZNF570
- ZNF773
- ZNF180
- ZNF234
- ZNF222
- ZNF254
- ZIK1
- ZSCAN21
- ZNF833P
- ZNF697
- ZNF550
- ZNF146
- ZNF121
- Nbla00121
- DKFZp686H10254
- DKFZp666M039
- ZNF323
- ZFP28
- POM121C
- KIAA1829
- FLJ00301
- ZNF525
- ZNF587B
- ZNF589
- ZFP1
- ZNF43
- ZNF700
- ZNF568
- KRBOX1
- ZNF677
- ZNF823
- ZNF264
- HKR1
- ZNF667
- ZNF702P
- ZNF660
- ZNF355P
- ZNF28
- ZF6
- DKFZp762K012
- ZKSCAN3
- ZKSCAN1
- ZNF155
- ZNF688
- ZNF510
- ZNF888
- ZNF17
- ZNF23
- ZNF485
- ZNF135
- ZNF141
- ZNF619
- ZNF836
- ZNF549
- ZNF486
- ZNF611
- ZNF528
- ZNF72
- ZNF648
- ZNF599
- ZNF768
- ZNF701
- ZNF468
- ZKSCAN2
- HZF17
- ZNF260
- ZKSCAN4
- ZNF211
- ZNF285
- ZNF12
- ZNF33B
- ZNF333
- ZNF672
- ZNF544
- ZNF578
- ZNF358
- ZNF286B
- DKFZp313M0722
- DKFZp434G1930
- ZNF552
- ZNF880
- PRDM9
- ZSCAN22
- ZNF80
- ZSCAN25
- ZNF852
- ZNF771
- ZNF746
- ZNF691
- ZNF498
- ZNF480
- ZNF449
- ZNF35
- ZNF132
- ZFS-1
- ZFP2
- ZNF137P
- ZNF221
- ZNF816
- ZNF610
- PRMD9
- ZNF73
- ZNF671
- ZNF605
- ZSCAN26
- ZNF883
- ZNF446
- ZNF391
- ZNF343
- HZF41
- ZNF32
- ZFS-2
- ZNF160
- ZNF548
- ZNF41
- ZNF626
- ZNF740
- ZNF71
- ZNF70
- ZNF436
- ZNF829
- ZNF805
- ZNF74
- ZNF736
- ZNF316
- ZNF271
- DKFZp686J1732
- ZNF157
- DKFZp570I0164
- ZNF841
- ZNF517
- ZNF2
- ZKSCAN5
- ZNF600
- ZNF782
- ZNF668
- ZNF629
- ZNF628
- ZNF329
- ZNF214
- DKFZp686G16228
- ZNF239
- ZNF154
- ZFP3
- ZNF547
- ZNF502
- ZSCAN2
- ZNF835
- ZNF679
- ZNF594
- ZNF16
- ZFP69
- ZNF337
- ZNF189
- ZIM3
- DKFZp547L155
- ZNF382
- ZNF658
- ZFP82
- ZNF587
- ZNF665
- ZNF658B
- ZNF606
- ZNF454
- ZNF404
- ZNF253
- MST154
- DKFZp686N14223
- DKFZp686L0787
- DKFZp686B16128
- ZNF136
- GFI1B
- ZNF473
- ZNF324
- ZNF678
- ZNF460
- ZNF25
- ZSCAN12
- ZNF92
- ZNF491
- ZNF490
- ZNF442
- ZNF765
- ZNF732
- ZNF727
- ZNF716
- ZNF676
- ZNF621
- ZNF497
- ZNF311
- ZNF182
- ZNF100
- ZKSCAN7
- HZF14
- GD
- DKFZp686H20223
- DKFZp571N1833
- ZNF345
- ZNF256
- ZNF184
- ZNF275
- ZNF792
- ZNF557
- ZNF334
- ZNF304
- ZSCAN31
- ZNF713
- ZNF699
- ZNF581
- ZNF483
- ZNF416
- ZNF394
- ZNF79
- ZNF772
- ZNF735
- ZNF730
- ZNF708
- ZNF623
- ZNF492
- ZFP62
- DKFZp686O111
- DKFZp686K03205
- DKFZp686C13142
- ZNF287
- ZBTB47
- ZNF57
- ZNF558
- ZNF99
- ZNF77
- ZNF813
- ZNF812
- ZNF799
- ZNF786
- ZNF69
- ZNF662
- ZNF643
- ZNF543
- ZNF354C
- ZNF30
- ZNF205
- ZNF14
- ZNF117
- ZFP69B
- ZFP112
- RhitH
- ZKSCAN8
- RBAK
- OSR2
- DKFZp434G1621
- CTCFL
- ZNF584
- ZNF572
- ZNF689
- ZNF564
- ZNF479
- ZNF891
- ZNF837
- ZNF714
- ZNF555
- ZNF441
- ZNF263
- ZFP92
- TIPUH1
- ZNF266
- ZNF165
- LOC126295
- ZNF20
- ZNF44
- ZNF8
- ZNF575
- ZNF563
- ZNF45
- ZNF37A
- ZSCAN10
- ZNF860
- ZNF729
- ZNF680
- ZFP37
- ZSCAN20
- ZNF840
- ZNF534
- ZNF530
- HZF11
- ZNF284
Variants for ZNF350 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF350 Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs115151289 | Benign: not provided | 51,965,074(-) |
G/A NM_021632.4(ZNF350):c.1379C>T (p.Ala460Val) |
MISSENSE | |
| rs2278415 | - |
p.Arg501Ser |
|||
| rs2278420 | - |
p.Leu66Pro |
|||
| rs28997584 | - |
p.Arg132Cys |
|||
| rs3764539 | - |
p.Glu406Lys |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1067e212 | CNV | gain | 25503493 |
| dgv143e55 | CNV | gain | 17911159 |
| dgv3626n100 | CNV | gain | 25217958 |
| dgv425n27 | CNV | gain | 19166990 |
| dgv6523n54 | CNV | gain | 21841781 |
| esv2242567 | CNV | deletion | 18987734 |
| esv2718779 | CNV | deletion | 23290073 |
| esv2758767 | CNV | gain+loss | 17122850 |
| nsv1125524 | CNV | deletion | 24896259 |
| nsv1140251 | OTHER | inversion | 24896259 |
| nsv525259 | CNV | loss | 19592680 |
| nsv580001 | CNV | gain | 21841781 |
| nsv580006 | CNV | loss | 21841781 |
| nsv833872 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
91.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.96;
79.85% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZNF350 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF350 Gene
Disorders for ZNF350 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| breast medullary carcinoma |
|
|
| benign breast phyllodes tumor |
|
|
| gastric cardia carcinoma |
|
|
Search ZNF350 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ZNF350
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF350 Gene
Publications for ZNF350 Gene
- Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1. (PMID: 11090615) Zheng L … Lee WH (Molecular cell 2000) 2 3 4 23
- Polymorphisms in BRCA1, BRCA1-interacting genes and susceptibility of breast cancer in Chinese women. (PMID: 19484476) Huo X … Tang J (Journal of cancer research and clinical oncology 2009) 3 23 41
- Genetic variants and haplotype analyses of the ZBRK1/ZNF350 gene in high-risk non BRCA1/2 French Canadian breast and ovarian cancer families. (PMID: 17764113) Desjardins S … Durocher F (International journal of cancer 2008) 3 23 41
- Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genes. (PMID: 15113441) Sigurdson AJ … Struewing JP (BMC cancer 2004) 3 23 41
- Characterization of a novel zinc finger gene with increased expression in nondividing normal human cells. (PMID: 11161714) Ran Q … Pereira-Smith OM (Experimental cell research 2001) 2 3 4
ExternalLinks
Products for ZNF350 Gene
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Sources for ZNF350 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
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