Aliases for ZNF347 Gene

Aliases for ZNF347 Gene

  • Zinc Finger Protein 347 2 3 4 5
  • ZNF1111 2 3 4
  • Zinc Finger Protein 1111 3 4
  • Zinc Finger 1111 3
  • CTD-2620I22.7 3
  • ZNF347 5

External Ids for ZNF347 Gene

Previous GeneCards Identifiers for ZNF347 Gene

  • GC19M054273
  • GC19M054002
  • GC19M058085
  • GC19M058103
  • GC19M058261
  • GC19M058334
  • GC19M053642
  • GC19M049965
  • GC19M053627

Summaries for ZNF347 Gene

GeneCards Summary for ZNF347 Gene

ZNF347 (Zinc Finger Protein 347) is a Protein Coding gene. Diseases associated with ZNF347 include Tinea Pedis and Pityriasis Versicolor. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF160.

UniProtKB/Swiss-Prot Summary for ZNF347 Gene

Additional gene information for ZNF347 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF347 Gene

Genomics for ZNF347 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ZNF347 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF347 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF347

Top Transcription factor binding sites by QIAGEN in the ZNF347 gene promoter:
  • AP-1
  • ATF-2
  • c-Jun
  • NF-AT2
  • NF-AT3
  • NF-AT4
  • p53
  • POU3F2
  • POU3F2 (N-Oct-5a)
  • POU3F2 (N-Oct-5b)

Genomic Locations for ZNF347 Gene

Genomic Locations for ZNF347 Gene
chr19:53,124,072-53,159,075
(GRCh38/hg38)
Size:
35,004 bases
Orientation:
Minus strand
chr19:53,627,325-53,662,328
(GRCh37/hg19)
Size:
35,004 bases
Orientation:
Minus strand

Genomic View for ZNF347 Gene

Genes around ZNF347 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF347 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF347 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF347 Gene

Proteins for ZNF347 Gene

  • Protein details for ZNF347 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96SE7-ZN347_HUMAN
    Recommended name:
    Zinc finger protein 347
    Protein Accession:
    Q96SE7
    Secondary Accessions:
    • B3KU77
    • B9EG59
    • G5E9N4
    • Q8TCN1

    Protein attributes for ZNF347 Gene

    Size:
    839 amino acids
    Molecular mass:
    95770 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for ZNF347 Gene

    Alternative splice isoforms for ZNF347 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF347 Gene

Post-translational modifications for ZNF347 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF347 Gene

Domains & Families for ZNF347 Gene

Gene Families for ZNF347 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF347 Gene

InterPro:
Blocks:
  • C2H2-type zinc finger signature
  • KRAB box
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF347 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 1111 (ZN347_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q96SE7

UniProtKB/Swiss-Prot:

ZN347_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF347: view

Function for ZNF347 Gene

Molecular function for ZNF347 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF347 Gene

Gene Ontology (GO) - Molecular Function for ZNF347 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF347: view
genes like me logo Genes that share phenotypes with ZNF347: view

Animal Model Products

CRISPR Products

miRNA for ZNF347 Gene

miRTarBase miRNAs that target ZNF347

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF347

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF347 Gene

Localization for ZNF347 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF347 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF347 gene
Compartment Confidence
nucleus 4
cytoskeleton 2
cytosol 2
extracellular 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF347 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF347: view

Pathways & Interactions for ZNF347 Gene

genes like me logo Genes that share pathways with ZNF347: view

Pathways by source for ZNF347 Gene

2 Reactome pathways for ZNF347 Gene
1 KEGG pathway for ZNF347 Gene

Interacting Proteins for ZNF347 Gene

Gene Ontology (GO) - Biological Process for ZNF347 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF347: view

No data available for SIGNOR curated interactions for ZNF347 Gene

Drugs & Compounds for ZNF347 Gene

No Compound Related Data Available

Transcripts for ZNF347 Gene

mRNA/cDNA for ZNF347 Gene

3 REFSEQ mRNAs :
15 NCBI additional mRNA sequence :
8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF347

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF347 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d · 4e ^ 5a · 5b ^ 6a · 6b · 6c
SP1: - - -
SP2: - -
SP3: - - -
SP4: - -
SP5: - -

Relevant External Links for ZNF347 Gene

GeneLoc Exon Structure for
ZNF347

Expression for ZNF347 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF347 Gene

Protein differential expression in normal tissues from HIPED for ZNF347 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF347 Gene



Protein tissue co-expression partners for ZNF347 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF347

SOURCE GeneReport for Unigene cluster for ZNF347 Gene:

Hs.467239

Evidence on tissue expression from TISSUES for ZNF347 Gene

  • Nervous system(4.3)
genes like me logo Genes that share expression patterns with ZNF347: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF347 Gene

Orthologs for ZNF347 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF347 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ZNF347 30
  • 99.4 (n)
-- 31
  • 53 (a)
ManyToMany
Cow
(Bos Taurus)
Mammalia -- 31
  • 50 (a)
ManyToMany
-- 31
  • 50 (a)
ManyToMany
-- 31
  • 49 (a)
ManyToMany
-- 31
  • 49 (a)
ManyToMany
-- 31
  • 44 (a)
ManyToMany
Mouse
(Mus musculus)
Mammalia Zfp51 31
  • 41 (a)
ManyToMany
Fruit Fly
(Drosophila melanogaster)
Insecta crol 32
  • 40 (a)
CG8484 32
  • 27 (a)
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 43 (a)
ManyToMany
-- 31
  • 39 (a)
ManyToMany
-- 31
  • 38 (a)
ManyToMany
-- 31
  • 36 (a)
ManyToMany
CSA.1668 31
  • 35 (a)
ManyToMany
-- 31
  • 33 (a)
ManyToMany
Species where no ortholog for ZNF347 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ZNF347 Gene

ENSEMBL:
Gene Tree for ZNF347 (if available)
TreeFam:
Gene Tree for ZNF347 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF347: view image

Paralogs for ZNF347 Gene

(517) SIMAP similar genes for ZNF347 Gene using alignment to 5 proteins:

  • ZN347_HUMAN
  • M0QXR8_HUMAN
  • M0QZE2_HUMAN
  • M0QZJ6_HUMAN
  • M0R1E9_HUMAN

Pseudogenes.org Pseudogenes for ZNF347 Gene

genes like me logo Genes that share paralogs with ZNF347: view

Variants for ZNF347 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF347 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs2195310 - p.Asn264Asp
rs34656962 - p.Met117Val

Additional dbSNP identifiers (rs#s) for ZNF347 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF347 Gene

Variant ID Type Subtype PubMed ID
esv2718787 CNV deletion 23290073
esv2758769 CNV loss 17122850
esv3644740 CNV gain 21293372
esv3644741 CNV gain 21293372
nsv1078889 OTHER inversion 25765185
nsv1141887 OTHER inversion 24896259
nsv428370 CNV loss 18775914
nsv472019 CNV novel sequence insertion 20440878
nsv478009 CNV novel sequence insertion 20440878
nsv960866 CNV duplication 23825009

Variation tolerance for ZNF347 Gene

Residual Variation Intolerance Score: 24% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.45; 28.43% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF347 Gene

Human Gene Mutation Database (HGMD)
ZNF347
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF347

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF347 Gene

Disorders for ZNF347 Gene

MalaCards: The human disease database

(4) MalaCards diseases for ZNF347 Gene - From: DISEASES

Disorder Aliases PubMed IDs
tinea pedis
  • athlete's foot
pityriasis versicolor
  • infection by pityrosporum furfur
pontiac fever
superficial mycosis
  • piedra
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with ZNF347: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF347 Gene

Publications for ZNF347 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  4. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3

Products for ZNF347 Gene

Sources for ZNF347 Gene