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Aliases for ZNF343 Gene

Aliases for ZNF343 Gene

  • Zinc Finger Protein 343 2 3 5
  • DJ734P14.5 3

External Ids for ZNF343 Gene

Previous GeneCards Identifiers for ZNF343 Gene

  • GC00U991036
  • GC20M002411
  • GC20M002412
  • GC20M002413
  • GC20M002414
  • GC20M002415
  • GC20M002416
  • GC20M002417
  • GC20M002418
  • GC20M002419
  • GC20M002420
  • GC20M002447
  • GC20M002462

Summaries for ZNF343 Gene

GeneCards Summary for ZNF343 Gene

ZNF343 (Zinc Finger Protein 343) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is HKR1.

UniProtKB/Swiss-Prot for ZNF343 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF343 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF343 Gene

Genomics for ZNF343 Gene

GeneHancer (GH) Regulatory Elements for ZNF343 Gene

Promoters and enhancers for ZNF343 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20I002507 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 562.7 +15.9 15932 2.6 PKNOX1 FOXA2 ARID4B SIN3A DMAP1 ZNF2 IRF4 YY1 POLR2B ZNF766 ZNF343 ENSG00000256566 SNRPB TMC2 SNORD56 SNORD57 NOP56 ENSG00000228293 IDH3B GC20M002474
GH20I002523 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 -0.5 -497 2.4 SMAD1 ARNT ARID4B SIN3A POLR2B ZNF766 ZNF213 ZNF143 SP3 MXD4 ZNF343 SNRPB VPS16 ITPA TMC2
GH20I002651 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 41.2 -128.5 -128503 4.2 HDGF SMAD1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 POLR2B NOP56 GC20M002651 GC20P002878 GC20P002887 PIR58104 SNORA51 SNORD110 MIR1292 GC20P002888 GC20P002881
GH20I002468 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 38.6 +54.7 54663 3.5 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC SNRPB VPS16 ZNF343 NOP56 ITPA UBOX5 GC20M002464 SNORD119 ENSG00000256566
GH20I002101 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 32.8 +421.6 421631 4.1 PKNOX1 CLOCK FOXA2 ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 STK35 GC20M002101 SNRPB VPS16 ZNF343 ACTG1P3 NOP56 ENSG00000229728 PCED1A GC20M002129
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF343 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF343 gene promoter:

Genomic Locations for ZNF343 Gene

Genomic Locations for ZNF343 Gene
44,632 bases
Minus strand

Genomic View for ZNF343 Gene

Genes around ZNF343 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF343 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF343 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF343 Gene

Proteins for ZNF343 Gene

  • Protein details for ZNF343 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 343
    Protein Accession:
    Secondary Accessions:
    • Q5JXU8
    • Q5JXU9
    • Q8N8F2
    • Q96EX8
    • Q96NA5
    • Q9BQB0

    Protein attributes for ZNF343 Gene

    599 amino acids
    Molecular mass:
    69220 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF343 Gene


neXtProt entry for ZNF343 Gene

Post-translational modifications for ZNF343 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF343 Gene

Domains & Families for ZNF343 Gene

Gene Families for ZNF343 Gene

Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF343 Gene

Suggested Antigen Peptide Sequences for ZNF343 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF343: view

Function for ZNF343 Gene

Molecular function for ZNF343 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF343 Gene

Gene Ontology (GO) - Molecular Function for ZNF343 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF343: view

Phenotypes for ZNF343 Gene

genes like me logo Genes that share phenotypes with ZNF343: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF343 Gene

Localization for ZNF343 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF343 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF343 gene
Compartment Confidence
nucleus 5

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF343 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF343: view

Pathways & Interactions for ZNF343 Gene

SuperPathways for ZNF343 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF343: view

Pathways by source for ZNF343 Gene

2 Reactome pathways for ZNF343 Gene

Gene Ontology (GO) - Biological Process for ZNF343 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF343: view

No data available for SIGNOR curated interactions for ZNF343 Gene

Drugs & Compounds for ZNF343 Gene

No Compound Related Data Available

Transcripts for ZNF343 Gene

Unigene Clusters for ZNF343 Gene

Zinc finger protein 343:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF343 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b
SP1: - - - - - - -
SP2: - - - - -
SP3: - -
SP4: -

Relevant External Links for ZNF343 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF343 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF343 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF343 Gene

Protein tissue co-expression partners for ZNF343 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF343 Gene:


SOURCE GeneReport for Unigene cluster for ZNF343 Gene:


Evidence on tissue expression from TISSUES for ZNF343 Gene

  • Kidney(4.2)
  • Lung(4.1)
  • Skin(4.1)
  • Blood(2.9)
genes like me logo Genes that share expression patterns with ZNF343: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF343 Gene

Orthologs for ZNF343 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF343 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF343 33 34
  • 99.61 (n)
Species where no ortholog for ZNF343 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF343 Gene

Gene Tree for ZNF343 (if available)
Gene Tree for ZNF343 (if available)

Paralogs for ZNF343 Gene

Paralogs for ZNF343 Gene

(461) SIMAP similar genes for ZNF343 Gene using alignment to 1 proteins: Pseudogenes for ZNF343 Gene

genes like me logo Genes that share paralogs with ZNF343: view

Variants for ZNF343 Gene

Sequence variations from dbSNP and Humsavar for ZNF343 Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs1000062112 -- 2,511,696(-) A/G genic_upstream_transcript_variant, intron_variant
rs1000188723 -- 2,501,390(-) G/C intron_variant
rs1000269316 -- 2,485,284(-) C/A genic_downstream_transcript_variant, intron_variant
rs1000367334 -- 2,496,957(-) G/A intron_variant
rs1000388501 -- 2,498,698(-) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF343 Gene

Variant ID Type Subtype PubMed ID
dgv40e213 CNV gain 24956385
esv1004398 CNV loss 20482838
esv2758778 CNV gain 17122850
esv3644998 CNV gain 21293372
esv3893269 CNV loss 25118596
nsv3260 CNV insertion 18451855
nsv470535 CNV gain 18288195

Variation tolerance for ZNF343 Gene

Residual Variation Intolerance Score: 85.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.17; 61.69% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF343 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF343 Gene

Disorders for ZNF343 Gene

Additional Disease Information for ZNF343

No disorders were found for ZNF343 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF343 Gene

Publications for ZNF343 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P … Rogers J (Nature 2001) 3 4 58
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for ZNF343 Gene

Sources for ZNF343 Gene

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