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Aliases for ZNF341 Gene

Aliases for ZNF341 Gene

  • Zinc Finger Protein 341 2 3 5

External Ids for ZNF341 Gene

Previous GeneCards Identifiers for ZNF341 Gene

  • GC20P032087
  • GC20P032988
  • GC20P033035
  • GC20P031783
  • GC20P032319
  • GC20P029105

Summaries for ZNF341 Gene

GeneCards Summary for ZNF341 Gene

ZNF341 (Zinc Finger Protein 341) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for ZNF341 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF341 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF341 Gene

Genomics for ZNF341 Gene

GeneHancer (GH) Regulatory Elements for ZNF341 Gene

Promoters and enhancers for ZNF341 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20I033731 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE 550.8 +1.6 1598 4 HDGF FOXA2 ARNT ARID4B SIN3A DMAP1 YBX1 ZNF2 YY1 SLC30A9 PIR41069 ZNF341 ENSG00000229188 ZNF341-AS1 CBFA2T2 RALY ASIP
GH20I033672 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 11.1 -57.3 -57300 4.5 SMAD1 FOXA2 ARID4B SIN3A DMAP1 ZNF2 ZNF213 KLF13 SP3 MXD4 NECAB3 ENSG00000271803 CBFA2T2 PXMP4 ZNF341 ENSG00000229188 E2F1 ZNF341-AS1 ASIP ACTL10
GH20I033561 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE dbSUPER 10 -169.3 -169307 1.2 ATF1 FOXA2 ARID4B DMAP1 ZNF2 ZNF48 YY1 TCF12 SLC30A9 ATF7 CBFA2T2 GC20P033562 C20orf144 ACTL10 NECAB3 PXMP4 ENSG00000229188 ZNF341 GC20P033491 GC20P033492
GH20I033553 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 10.2 -176.7 -176713 3.1 HDGF PKNOX1 FOXA2 MLX ZNF48 YY1 ATF7 RXRA NFYC MIER2 CBFA2T2 C20orf144 ACTL10 NECAB3 PXMP4 ZNF341 ENSG00000229188 CDK5RAP1 CHMP4B BPIFB4
GH20I033777 Enhancer 1.3 FANTOM5 Ensembl ENCODE 11.2 +47.4 47388 2.8 HDGF PKNOX1 FOXA2 IRF4 ZNF207 ZNF143 ATF7 RUNX3 RXRA ZNF623 ZNF341-AS1 CHMP4B ZNF341 ENSG00000229188 PXMP4 E2F1 BPIFA2 GC20M033791 RPL31P2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF341 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF341 gene promoter:

Genomic Locations for ZNF341 Gene

Genomic Locations for ZNF341 Gene
chr20:33,731,657-33,792,269
(GRCh38/hg38)
Size:
60,613 bases
Orientation:
Plus strand
chr20:32,319,463-32,380,075
(GRCh37/hg19)

Genomic View for ZNF341 Gene

Genes around ZNF341 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF341 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF341 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF341 Gene

Proteins for ZNF341 Gene

  • Protein details for ZNF341 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BYN7-ZN341_HUMAN
    Recommended name:
    Zinc finger protein 341
    Protein Accession:
    Q9BYN7
    Secondary Accessions:
    • A2RUF4
    • B2RXE5
    • B7ZM09
    • Q5JXM8
    • Q96ST5

    Protein attributes for ZNF341 Gene

    Size:
    854 amino acids
    Molecular mass:
    92728 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB55193.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF341 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF341 Gene

Post-translational modifications for ZNF341 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF341 Gene

No data available for DME Specific Peptides for ZNF341 Gene

Domains & Families for ZNF341 Gene

Gene Families for ZNF341 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF341 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF341 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BYN7

UniProtKB/Swiss-Prot:

ZN341_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF341: view

Function for ZNF341 Gene

Molecular function for ZNF341 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF341 Gene

Gene Ontology (GO) - Molecular Function for ZNF341 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IBA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF341: view

Phenotypes for ZNF341 Gene

genes like me logo Genes that share phenotypes with ZNF341: view

miRNA for ZNF341 Gene

miRTarBase miRNAs that target ZNF341

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF341 Gene

Localization for ZNF341 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF341 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF341 gene
Compartment Confidence
nucleus 5
cytoskeleton 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF341 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF341: view

Pathways & Interactions for ZNF341 Gene

SuperPathways for ZNF341 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF341 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF341: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF341 Gene

Drugs & Compounds for ZNF341 Gene

No Compound Related Data Available

Transcripts for ZNF341 Gene

Unigene Clusters for ZNF341 Gene

Zinc finger protein 341:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF341 Gene

No ASD Table

Relevant External Links for ZNF341 Gene

GeneLoc Exon Structure for
ZNF341
ECgene alternative splicing isoforms for
ZNF341

Expression for ZNF341 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF341 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF341 Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF341 Gene



Protein tissue co-expression partners for ZNF341 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF341 Gene:

ZNF341

SOURCE GeneReport for Unigene cluster for ZNF341 Gene:

Hs.516989
genes like me logo Genes that share expression patterns with ZNF341: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF341 Gene

Orthologs for ZNF341 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF341 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF341 33 34
  • 99.61 (n)
cow
(Bos Taurus)
Mammalia ZNF341 33 34
  • 90.52 (n)
dog
(Canis familiaris)
Mammalia ZNF341 33 34
  • 90.39 (n)
mouse
(Mus musculus)
Mammalia Zfp341 33 16 34
  • 86.26 (n)
rat
(Rattus norvegicus)
Mammalia Zfp966 33
  • 86.13 (n)
oppossum
(Monodelphis domestica)
Mammalia ZNF341 34
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF341 34
  • 78 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF341 33 34
  • 75.3 (n)
lizard
(Anolis carolinensis)
Reptilia ZNF341 34
  • 73 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia znf341 33
  • 64.3 (n)
zebrafish
(Danio rerio)
Actinopterygii znf341 33 34
  • 67.61 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1289 34
  • 30 (a)
OneToOne
Species where no ortholog for ZNF341 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF341 Gene

ENSEMBL:
Gene Tree for ZNF341 (if available)
TreeFam:
Gene Tree for ZNF341 (if available)

Paralogs for ZNF341 Gene

Pseudogenes.org Pseudogenes for ZNF341 Gene

genes like me logo Genes that share paralogs with ZNF341: view

No data available for Paralogs for ZNF341 Gene

Variants for ZNF341 Gene

Sequence variations from dbSNP and Humsavar for ZNF341 Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs368945563 likely-benign, Long QT syndrome 33,791,116(+) C/T coding_sequence_variant, genic_downstream_transcript_variant, missense_variant, non_coding_transcript_variant
rs1000055059 -- 33,740,438(+) G/C intron_variant
rs1000133111 -- 33,791,782(+) G/A 3_prime_UTR_variant, genic_downstream_transcript_variant, non_coding_transcript_variant
rs1000294859 -- 33,752,629(+) G/A intron_variant
rs1000319257 -- 33,752,088(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF341 Gene

Variant ID Type Subtype PubMed ID
dgv2242n106 CNV deletion 24896259
esv2659244 CNV deletion 23128226
esv2676051 CNV deletion 23128226
esv3575370 CNV gain 25503493
nsv1065189 CNV loss 25217958
nsv1072535 CNV deletion 25765185
nsv180563 CNV deletion 16902084
nsv3353 CNV deletion 18451855
nsv3355 CNV insertion 18451855
nsv458965 CNV gain 19166990
nsv470548 CNV gain 18288195
nsv518926 CNV gain 19592680
nsv585930 CNV gain 21841781
nsv828714 CNV loss 20364138
nsv833961 CNV loss 17160897
nsv962572 CNV duplication 23825009

Variation tolerance for ZNF341 Gene

Residual Variation Intolerance Score: 54.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.72; 57.53% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF341 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF341

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF341 Gene

Disorders for ZNF341 Gene

Additional Disease Information for ZNF341

No disorders were found for ZNF341 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF341 Gene

Publications for ZNF341 Gene

  1. Hundreds of variants clustered in genomic loci and biological pathways affect human height. (PMID: 20881960) Lango Allen H … Hirschhorn JN (Nature 2010) 3 44 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P … Rogers J (Nature 2001) 3 4 58
  4. The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease. (PMID: 24705354) Butland SL … Hayden MR (Human molecular genetics 2014) 3 58
  5. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R … Iakoucheva LM (Nature communications 2014) 3 58

Products for ZNF341 Gene

Sources for ZNF341 Gene

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