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This gene encodes a member of the C2H2 zinc finger family. The encoded protein contains a Krueppel-associated box, fourteen C2H2 zinc finger domains, and four C2H2-type/integrase DNA-binding domains. Decreased expression of this gene may be a marker for rheumatoid arthritis. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [pr... See more...
Aliases for ZNF334 Gene
External Ids for ZNF334 Gene
- HGNC: 15806
- Entrez Gene: 55713
- Ensembl: ENSG00000198185
- UniProtKB: Q9HCZ1
Previous GeneCards Identifiers for ZNF334 Gene
- GC20M044858
- GC20M045682
- GC20M045729
- GC20M045263
- GC20M044563
- GC20M045129
- GC20M041870
- GC20M046499
Summaries for ZNF334 Gene
-
This gene encodes a member of the C2H2 zinc finger family. The encoded protein contains a Krueppel-associated box, fourteen C2H2 zinc finger domains, and four C2H2-type/integrase DNA-binding domains. Decreased expression of this gene may be a marker for rheumatoid arthritis. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
GeneCards Summary for ZNF334 Gene
ZNF334 (Zinc Finger Protein 334) is a Protein Coding gene. Diseases associated with ZNF334 include Rheumatoid Arthritis. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF658.
UniProtKB/Swiss-Prot Summary for ZNF334 Gene
-
May be involved in transcriptional regulation.
Additional gene information for ZNF334 Gene
- HGNC(15806)
- Entrez Gene(55713)
- Ensembl(ENSG00000198185)
- UniProtKB(Q9HCZ1)
- Open Targets Platform(ENSG00000198185)
- Search for ZNF334 at DataMed
- Search for ZNF334 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF334 Gene
Genomics for ZNF334 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ZNF334 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ZNF334 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF334
- Top Transcription factor binding sites by QIAGEN in the ZNF334 gene promoter:
-
- AREB6
- GATA-1
- GATA-2
- GATA-3
- HNF-3beta
- LCR-F1
- PPAR-alpha
Genomic Locations for ZNF334 Gene
Genomic Locations for ZNF334 Gene
- chr20:46,463,660-46,513,572
- (GRCh38/hg38)
- Size:
- 49,913 bases
- Orientation:
- Minus strand
- chr20:45,129,701-45,142,198
- (GRCh37/hg19)
- Size:
- 12,498 bases
- Orientation:
- Minus strand
Genomic View for ZNF334 Gene
Genes around ZNF334 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 20q13.12 by HGNC
- 20q13.12 by Entrez Gene
- 20q13.12 by Ensembl
ZNF334 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZNF334 Gene
Proteins for ZNF334 Gene
-
Protein details for ZNF334 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9HCZ1-ZN334_HUMAN
- Recommended name:
- Zinc finger protein 334
- Protein Accession:
- Q9HCZ1
- Q5T6U2
- Q9NVW4
Protein attributes for ZNF334 Gene
- Size:
- 680 amino acids
- Molecular mass:
- 79649 Da
- Quaternary structure:
- No Data Available
Protein Expression for ZNF334 Gene
Post-translational modifications for ZNF334 Gene
Other Protein References for ZNF334 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- XP_011527194.1
- XP_011527199.1
- XP_016883424.1
- XP_016883426.1
- XP_016883433.1
- XP_024307705.1
- XP_024307706.1
- XP_024307707.1
- XP_024307708.1
- XP_024307709.1
- XP_024307710.1
- XP_024307711.1
- XP_024307712.1
- XP_024307713.1
- NP_001257426.1
- NP_001340742.1
- NP_001340743.1
- NP_001340744.1
- NP_001340745.1
- NP_001340746.1
- NP_001340747.1
- NP_001340748.1
- NP_001340749.1
- NP_001340750.1
- NP_001340751.1
- NP_001340752.1
- NP_001340753.1
- NP_001340754.1
- NP_001340755.1
- NP_060572.3
- NP_955473.1
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ZNF334
- Novus Biologicals Antibodies for ZNF334
- Invitrogen Antibodies for ZNF334 (AFLGC-ZNF334)
- antibodies-online: Show 3 available ZNF334 Antibodies ranked by validation data
- Compare Top ZNF334 Antibodies
-
Quality Products:
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for ZNF334
- Origene Custom Protein Services for ZNF334
- antibodies-online: Show 2 available ZNF334 Proteins ranked by validation data
- Compare Top ZNF334 Proteins
-
Quality Products:
-
Abcam proteins for ZNF334
No data available for DME Specific Peptides for ZNF334 Gene
Domains & Families for ZNF334 Gene
Gene Families for ZNF334 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZNF334 Gene
- InterPro:
- Blocks:
-
- KRAB box
- ProtoNet:
Suggested Antigen Peptide Sequences for ZNF334 Gene
- GenScript: Design optimal peptide antigens:
-
- Zinc finger protein 334 (Q5XKG8_HUMAN)
- Zinc finger protein 334 (ZN334_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9HCZ1- Family:
-
- Belongs to the krueppel C2H2-type zinc-finger protein family.
Function for ZNF334 Gene
Molecular function for ZNF334 Gene
- UniProtKB/Swiss-Prot Function:
- May be involved in transcriptional regulation.
Phenotypes From GWAS Catalog for ZNF334 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 16189514 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ZNF334 Gene
- MGI mutant phenotypes for ZNF334:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ZNF334:
-
- no effect
- Synthetic lethal with MLN4924 (a NAE inhibitor)
- Increased viability with MLN4924 (a NAE inhibitor)
- Strongly decreased CFP-tsO45G cell surface transport
- Decreased endosome-nucleus distance (endosomes clustered in the perinuclear region)
- Decreased viability in pancreas lineage
- Decreased shRNA abundance (Z-score < -2)
- Increased shRNA abundance (Z-score > 2)
- Effect on mitosis
Animal Models for ZNF334 Gene
- MGI Knock Outs for ZNF334:
-
- Zfp334 Zfp334<tm1.1(KOMP)Vlcg>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ZNF334 - Select products 50% OFF >
- * ZNF334 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ZNF334
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF334
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF334
miRNA for ZNF334 Gene
- miRTarBase miRNAs that target ZNF334
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF334
- Browse OriGene Inhibitory RNA Products For ZNF334
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF334
Clone Products
- Applied Biological Materials (abm): Clones for ZNF334 - Select products 50% OFF >
- * ZNF334 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ZNF334
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF334
Cell Line Products
-
Horizon Cell Lines for ZNF334
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ZNF334 Gene
Localization for ZNF334 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZNF334 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 2 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
Pathways & Interactions for ZNF334 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Gene Expression |
.48
|
|
| 2 | Herpes simplex virus 1 infection | ||
Pathways by source for ZNF334 Gene
2 Reactome pathways for ZNF334 Gene
1 KEGG pathway for ZNF334 Gene
Interacting Proteins for ZNF334 Gene
Selected Interacting proteins:
Q9HCZ1-ZN334_HUMAN
ENSP00000255129
for ZNF334 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for ZNF334
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
No data available for SIGNOR curated interactions for ZNF334 Gene
Transcripts for ZNF334 Gene
mRNA/cDNA for ZNF334 Gene
- 17 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000347606 3890 nts (view in UCSC)
- ENST00000457685 3487 nts (view in UCSC)
- ENST00000593880 2635 nts (view in UCSC)
- ENST00000596323 2243 nts (view in UCSC)
- ENST00000615481 3706 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ZNF334 - Select products 50% OFF >
- * ZNF334 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ZNF334
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF334
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF334
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF334
- Browse OriGene Inhibitory RNA Products For ZNF334
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF334
Clone Products
- Applied Biological Materials (abm): Clones for ZNF334 - Select products 50% OFF >
- * ZNF334 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ZNF334
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF334
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | ||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||
| SP5: | - |
Relevant External Links for ZNF334 Gene
- GeneLoc Exon Structure for
- ZNF334
Expression for ZNF334 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Heart (Cardiovascular System)
- Endocardial Tube Cells Endocardium
- Eye (Sensory Organs)
This gene is overexpressed in Cervix (68.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF334 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF334
SOURCE GeneReport for Unigene cluster for ZNF334 Gene:
Hs.147041Primer Products
-
OriGene qPCR primer pairs for ZNF334
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF334 Gene
Orthologs for ZNF334 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ZNF334 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | LOC685574 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Zfp334 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
| Dog (Canis familiaris) |
Mammalia | -- 31 |
|
ManyToMany | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
ManyToMany | |
| Cow (Bos Taurus) |
Mammalia | -- 31 |
|
ManyToMany | |
| Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
| Zebrafish (Danio rerio) |
Actinopterygii | CU207245.2 31 |
|
ManyToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
ManyToMany | |
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany |
- Species where no ortholog for ZNF334 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for ZNF334 Gene
- ENSEMBL:
- Gene Tree for ZNF334 (if available)
- TreeFam:
- Gene Tree for ZNF334 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ZNF334: view image
Paralogs for ZNF334 Gene
Paralogs for ZNF334 Gene
- ZNF658 5
- ZNF33B 5
- ZNF33A 5
- ZNF717 5
- ZNF182 5
- ZNF484 5
- ZNF41 5
- ZNF585B 5
- ZNF585A 5
- ZNF12 5
- ZNF268 5
- ZNF229 5
- ZNF624 5
- RBAK 5
- ZNF630 5
- ZNF197 5
- ZNF93 5
- ZNF7 5
- ZNF429 5
- ZNF85 5
- ZNF726 5
- ZNF254 5
- ZNF546 5
- ZNF175 5
- ZNF841 5
- ZNF470 5
- ZNF606 5
- ZNF782 5
- ZNF605 5
- ZNF45 5
- ZNF234 5
- ZNF226 5
- ZNF595 5
- ZFP14 5
- ZNF345 5
- ZNF30 5
- ZNF568 5
- ZNF502 5
- ZNF708 5
- ZNF493 5
- ZNF699 5
- ZNF571 5
- ZNF43 5
- ZNF681 5
- ZNF354B 5
- ZNF16 5
- ZNF615 5
- ZNF432 5
- ZNF23 5
- ZFP28 5
- ZNF135 5
- ZNF544 5
- ZNF189 5
- ZNF37A 5
- ZNF300 5
- ZNF235 5
- ZNF227 5
- ZNF732 5
- ZNF540 5
- ZNF573 5
- ZNF724 5
- ZNF250 5
- ZNF354A 5
- ZNF879 5
- ZNF836 5
- ZNF471 5
- ZNF311 5
- ZNF510 5
- ZNF157 5
- ZNF251 5
- ZNF81 5
- ZNF283 5
- ZNF112 5
- ZNF565 5
- ZFP82 5
- ZNF461 5
- ZNF790 5
- ZNF90 5
- ZFP30 5
- ZNF728 5
- ZNF678 5
- ZFP2 5
- ZNF26 5
- ZNF780B 5
- ZNF629 5
- ZNF616 5
- ZNF534 5
- ZNF83 5
- ZNF28 5
- ZNF543 5
- ZNF814 5
- ZNF132 5
- ZNF623 5
- ZNF483 5
- ZNF267 5
- ZNF383 5
- ZNF714 5
- ZNF607 5
- ZNF676 5
- ZNF492 5
- ZNF780A 5
- ZNF880 5
- ZNF528 5
- ZNF611 5
- ZNF71 5
- ZNF835 5
- ZFP3 5
- ZNF221 5
- ZNF224 5
- ZNF260 5
- ZNF682 5
- ZNF436 5
- ZNF454 5
- ZNF354C 5
- ZNF74 5
- ZNF695 5
- ZNF600 5
- ZNF415 5
- ENSG00000285447 5
- ZNF727 5
- ZNF117 5
- ZNF284 5
- ZNF317 5
- ZNF490 5
- ENSG00000233757 5
- ZNF140 5
- ZNF331 5
- ZNF286A 5
- ENSG00000255104 5
- ZNF225 5
- ZNF718 5
- ZNF829 5
- ZNF320 5
- ZNF716 5
- ZKSCAN5 5
- ZNF141 5
- ZNF519 5
- ZNF577 5
- ZNF677 5
- ZNF195 5
- ZNF628 5
- ZNF460 5
- ZNF736 5
- ZNF486 5
- ZNF121 5
- ZIM3 5
- MZF1 5
- ZNF322 5
- ZNF3 5
- ZNF506 5
- ZNF672 5
- ZNF775 5
- ZNF735 5
- ZNF679 5
- ZNF655 5
- ZNF391 5
- ZSCAN10 5
- ZFP1 5
- ZNF2 5
- ZNF239 5
- ZNF517 5
- ZNF146 5
- ZNF514 5
- ZNF722P 5
- ZNF501 5
- ZNF789 5
- ZNF713 5
- ZNF621 5
- GLI4 5
- ZNF696 5
- ZNF32 5
- ZNF138 5
- ZIM2 5
- ENSG00000269693 5
- ENSG00000285978 5
- ENSG00000283930 5
- RBAK-RBAKDN 5
- ENSG00000267360 5
- ENSG00000267552 5
- ENSG00000267173 5
- ENSG00000283515 5
(466) SIMAP similar genes for ZNF334 Gene using alignment to 3 proteins:
- ZN334_HUMAN
- M0R3E1_HUMAN
- Q5XKG8_HUMAN
- DKFZp572F2170
- KRBOX4
- ZNF78L1
- kr-znf3
- ZSCAN30
- ZSCAN16
- ZNF
- MGC12518
- DKFZp686M04222
- ZNF248
- ZNF702P
- ZFS-5
- ZNF81
- ZSCAN23
- ZNF391
- ZNF167
- ZKSCAN8
- ZNF501
- HZF30
- DKFZp686D2168
- ZNF32
- ZFS-6
- ZFS-4
- ZSCAN31
- ZSCAN22
- ZNF844
- ZNF323
- HZF16
- DKFZp666C237
- DKFZp313M0722
- ZNF780A
- ZNF260
- ZNF569
- ZSCAN9
- ZNF726P1
- ZNF72
- ZNF691
- ZNF660
- ZNF852
- ZNF146
- ZNF232
- ZFP41
- HZF36
- DKFZp686N0199
- ZNF510
- ZNF250
- ZNF345
- ZNF33B
- ZNF684
- zf30
- ZSCAN21
- ZNF664
- ZNF169
- DKFZp686B16128
- ZNF137P
- HZF40
- DKFZp686H10254
- ZNF418
- ZNF714
- ZNF577
- ZNF791
- ZNF833P
- ZNF80
- ZNF696
- ZNF589
- ZNF55
- ZNF883
- ZNF835
- ZNF658B
- ZNF658
- ZNF397
- ZNF124
- DKFZp434G1930
- ZNF724P
- ZSCAN20
- ZNF665
- ZNF300P1
- ZNF485
- ZNF66
- smap-7
- ZNF436
- ZNF73
- ZNF35
- ZNF286B
- DKFZp686K03205
- DKFZp666M039
- ZNF22
- ZKSCAN3
- ZNF83
- ZNF558
- ZNF234
- ZNF774
- ZNF487
- ZNF17
- ZNF12
- ZNF615
- ZNF43
- ZNF85
- ZNF708
- ZNF355P
- ZNF331
- ZNF271
- DKFZp686H20223
- DKFZp571N1833
- ZNF273
- RhitH
- GLI4
- ZNF595
- ZFP2
- ZNF808
- ZNF449
- ZNF616
- ZNF470
- ZNF117
- ZFP1
- ZNF726
- ZNF493
- ZSCAN29
- ZNF818P
- ZNF771
- ZNF669
- ZNF625
- ZNF621
- ZNF502
- ZNF814
- ZNF572
- ZNF497
- ZNF329
- ZNF16
- ZFS-1
- ZFP69
- HZF41
- DKFZp547L155
- ZNF107
- DKFZp547H249
- DKFZp434J0650
- ZNF33A
- ZNF780B
- ZNF600
- ZNF257
- ZNF678
- ZNF91
- ZNF93
- ZNF643
- ZNF624
- ZNF57
- ZNF268
- ZNF254
- ZFP69B
- LOC126295
- DKFZp686O111
- ZNF286A
- RBAK
- ZNF630
- ZNF84
- ZNF566
- ZNF805
- ZNF135
- ZIM3
- ZNF782
- PRDM9
- ZNF682
- ZNF266
- HZF11
- ZNF3
- MST154
- HZF17
- DKFZp570I0164
- ZNF585A
- ZNF283
- ZNF300
- PRMD9
- ZNF709
- ZNF90
- ZNF629
- ZNF546
- ZNF534
- ZNF14
- ZNF287
- ZNF197
- ZNF189
- ZNF619
- ZNF730
- ZNF140
- ZNF141
- ZNF707
- ZNF697
- ZNF585B
- ZNF571
- ZNF836
- ZNF761
- ZNF605
- ZNF568
- ZNF347
- ZNF239
- ZNF229
- ZNF184
- ZFP62
- Nbla00121
- HZF14
- ZFS-2
- OSR2
- DKFZp762K012
- ZNF442
- ZNF717
- ZNF2
- ZNF100
- ZNF582
- ZNF620
- ZNF611
- ZNF607
- ZNF486
- ZNF429
- ZNF251
- ZNF226
- ZFP90
- ZNF136
- ZNF614
- ZNF420
- ZNF441
- ZSCAN26
- ZNF785
- ZNF705A
- ZNF70
- ZNF559
- ZNF514
- ZNF415
- ZNF845
- ZNF829
- ZNF816
- ZNF813
- ZNF721
- ZNF594
- ZNF549
- ZNF484
- ZNF256
- ZNF223
- ZNF182
- ZNF132
- ZNF23
- ZFP3
- A-328A3.4
- ZNF718
- ZNF28
- ZNF7
- ZNF433
- ZNF567
- ZNF790
- ZNF599
- ZNF544
- ZNF540
- ZNF471
- ZNF432
- ZNF41
- ZNF383
- ZNF99
- ZNF850
- ZNF823
- ZNF79
- ZNF667
- ZNF460
- ZNF443
- ZFP92
- DKFZp686L0787
- ZNF333
- ZNF157
- ZNF160
- ZNF557
- ZNF71
- ZSCAN2
- ZNF98
- ZNF878
- ZNF788
- ZNF716
- ZNF623
- ZNF586
- ZNF555
- ZNF530
- ZNF222
- ZNF112
- ZNF284
- ZNF154
- ZFP28
- ZNF181
- ZNF92
- ZNF419
- ZNF304
- ZNF793
- ZNF700
- ZNF527
- ZNF337
- ZNF841
- ZNF749
- ZNF737
- ZNF729
- ZNF699
- ZNF681
- ZNF573
- ZNF543
- ZNF492
- ZNF30
- ZNF230
- ZNF225
- DKFZp686N14223
- ZNF175
- ZFP14
- ZNF799
- ZNF133
- ZNF134
- ZNF77
- ZNF45
- ZNF8
- ZNF732
- ZNF519
- ZNF468
- ZNF322
- ZNF224
- ZKSCAN7
- ZFP112
- DKFZp686G16228
- ZNF263
- ZNF180
- ZKSCAN4
- ZBTB41
- KIAA1829
- HZF28
- ZNF551
- ZNF570
- ZNF789
- ZNF713
- ZNF671
- ZNF670
- ZNF627
- ZNF354B
- ZNF888
- ZNF728
- ZNF701
- ZNF610
- ZNF554
- ZNF404
- ZNF350
- ZNF343
- ZNF227
- ZNF578
- ZNF19
- ZNF773
- ZNF672
- ZNF581
- ZNF891
- ZNF880
- ZNF860
- ZNF69
- ZNF676
- ZNF584
- ZNF547
- ZNF491
- ZNF44
- ZNF417
- ZNF26
- DKFZp686C13142
- ZFP37
- ZNF302
- ZNF564
- ZNF426
- ZNF879
- ZNF720
- ZNF695
- ZNF548
- ZNF528
- ZNF354A
- ZNF285A
- ZNF267
- ZNF221
- ZNF20
- ZNF195
- ZNF177
- ZNF155
- HKR1
- DKFZp686J1732
- ZNF208
- ZNF101
- ZNF10
- ZNF766
- ZNF74
- ZNF649
- ZNF517
- ZNFN1A2
- ZNF662
- ZNF467
- ZNF768
- ZNF727
- ZNF674
- ZNF583
- ZNF506
- ZNF480
- ZNF473
- ZNF264
- ZFS-3
- DKFZp686O1631
- ZNF560
- ZNF425
- ZNF37A
- ZNF846
- ZNF840
- ZNF778
- ZNF679
- ZNF613
- ZNF529
- ZNF454
- ZNF431
- ZNF311
- ZNF235
- GD
- ZFP30
- ZNF382
- ZNF430
- ZFP82
- ZNF416
- ZNF285
- ZNF25
- ZNF597
- ZNF561
- ZNF792
- ZNF606
- ZNF596
- ZNF445
- ZNF211
- ZIK1
- ZNF525
- ZSCAN12
- ZNF563
- ZNF439
- ZNF735
- ZNF675
- ZNF626
- ZNF490
- ZNF320
- PRDM5
- MZF1
- CTCFL
- ZNF705D
- ZNF483
- ZNF765
- ZNF736
- ZNF121
- ZNF114
- ZBTB47
- HKR3
- GFI1B
- ZNF776
- ZNF275
- ZNF565
- ZNF772
- ZNF677
- ZNF354C
- ZNF34
- ZNF587B
- ZNF587
- ZNF575
- ZNF556
- ZNF668
- ZNF655
- ZNF319
- ZNF253
- REPIN1
- DKFZp434G1621
Variants for ZNF334 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF334 Gene
| SNP ID | Clinical significance and condition | Chr 20 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs3764690 | - | p.Asn547Ser |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3645954 | CNV | loss | 21293372 |
| nsv1061899 | CNV | loss | 25217958 |
| nsv833994 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
74.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.71;
46.39% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZNF334 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ZNF334
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF334 Gene
Disorders for ZNF334 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| rheumatoid arthritis |
|
|
Search ZNF334 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ZNF334
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF334 Gene
Publications for ZNF334 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P … Rogers J (Nature 2001) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- The in vitro modulatory effect of TNFα on the mRNA expression and protein levels of zinc finger protein ZNF334 in CD4(+) lymphocytes of healthy people. (PMID: 25738173) Henc I … Witkowski JM (Acta biochimica Polonica 2015) 3
ExternalLinks
Products for ZNF334 Gene
- Custom Antibody ServicesOriGene Antibodies for ZNF334
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- Sino Biological Human cDNA Clone for ZNF334
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- Novus Biologicals proteins and lysates for ZNF334
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- Browse Primary Antibodies
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- Invitrogen Antibodies for ZNF334 (AFLGC-ZNF334)
- VectorBuilder Custom and pre-made DNA vectors for ZNF334 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for ZNF334 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for ZNF334 (ie. knockout, knockin, CRISPRa, CRISPRi)
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- VectorBuilder Stable cell line generation for ZNF334
- antibodies-online: Show 3 available ZNF334 Antibodies ranked by validation data
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- antibodies-online: Show 2 available ZNF334 Proteins ranked by validation data
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- Search GeneCopoeia for miRNA 3'UTR Target clone products for ZNF334
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF334
Sources for ZNF334 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB