Aliases for ZNF329 Gene

Aliases for ZNF329 Gene

  • Zinc Finger Protein 329 2 3 4 5

External Ids for ZNF329 Gene

Previous GeneCards Identifiers for ZNF329 Gene

  • GC00U990857
  • GC19M063330
  • GC19M058637
  • GC19M054948

Summaries for ZNF329 Gene

GeneCards Summary for ZNF329 Gene

ZNF329 (Zinc Finger Protein 329) is a Protein Coding gene. Diseases associated with ZNF329 include Kbg Syndrome. An important paralog of this gene is ZNF180.

UniProtKB/Swiss-Prot Summary for ZNF329 Gene

Additional gene information for ZNF329 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF329 Gene

Genomics for ZNF329 Gene

GeneHancer (GH) Regulatory Elements for ZNF329 Gene

Promoters and enhancers for ZNF329 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J058149 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 509.1 +4.8 4809 2.6 NRF1 POLR2G PHF8 POLR2A ZBTB10 ZBTB26 TAF9B HDAC2 KMT2B SIN3A ZNF329 ZSCAN18 ENSG00000176593 ENSG00000268201 ZIK1 ZNF549 ZNF587 lnc-ZNF329-1 piR-49732-296
GH19J058153 Promoter/Enhancer 1.7 Ensembl ENCODE CraniofacialAtlas 508.3 +0.2 244 2.3 ZBTB40 ZNF217 CTCF NRF1 POLR2G SIX5 ZFX ZNF639 ZBTB10 GABPA ZNF329 ENSG00000286632 lnc-ZNF329-1 ENSG00000269054 ENSG00000268543 ZSCAN18 piR-49732-296
GH19J058144 Promoter 0.5 EPDnew 500.4 +10.4 10372 0.1 ZFP91 NFIB ZNF329 piR-43583-281 ENSG00000268293 lnc-ZNF274-4 lnc-ZNF329-1
GH19J058154 Enhancer 0.3 ENCODE 506.4 +1.5 1541 0.2 GATA3 FOXA1 ZNF329 lnc-ZNF329-1 piR-49732-296
GH19J058379 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas 60.6 -226.2 -226190 3.8 RXRA EP300 HNRNPK ZBTB40 ZNF217 NRF1 MYC TCF12 USF1 POLR2G ZNF837 lnc-RPS5-3 ENSG00000176593 ZNF329 ZNF135 ZNF132 ZNF446 ZNF606 ZSCAN18 ZNF549
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF329 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF329

Top Transcription factor binding sites by QIAGEN in the ZNF329 gene promoter:
  • YY1

Genomic Locations for ZNF329 Gene

Genomic Locations for ZNF329 Gene
chr19:58,126,248-58,155,110
(GRCh38/hg38)
Size:
28,863 bases
Orientation:
Minus strand
chr19:58,637,619-58,666,477
(GRCh37/hg19)
Size:
28,859 bases
Orientation:
Minus strand

Genomic View for ZNF329 Gene

Genes around ZNF329 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF329 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF329 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF329 Gene

Proteins for ZNF329 Gene

  • Protein details for ZNF329 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86UD4-ZN329_HUMAN
    Recommended name:
    Zinc finger protein 329
    Protein Accession:
    Q86UD4
    Secondary Accessions:
    • B3KR32
    • Q9H9R7

    Protein attributes for ZNF329 Gene

    Size:
    541 amino acids
    Molecular mass:
    61725 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14154.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};

neXtProt entry for ZNF329 Gene

Post-translational modifications for ZNF329 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF329 Gene

Domains & Families for ZNF329 Gene

Gene Families for ZNF329 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF329 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF329 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 329 (ZN329_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q86UD4

UniProtKB/Swiss-Prot:

ZN329_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF329: view

Function for ZNF329 Gene

Molecular function for ZNF329 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF329 Gene

Gene Ontology (GO) - Molecular Function for ZNF329 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA-binding transcription factor activity IBA 21873635
GO:0005515 protein binding IPI 25416956
GO:0043565 sequence-specific DNA binding IBA 21873635
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF329: view
genes like me logo Genes that share phenotypes with ZNF329: view

Animal Model Products

CRISPR Products

miRNA for ZNF329 Gene

miRTarBase miRNAs that target ZNF329

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF329

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF329 Gene

Localization for ZNF329 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF329 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF329 gene
Compartment Confidence
nucleus 4
cytosol 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear membrane (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF329 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA 21873635
genes like me logo Genes that share ontologies with ZNF329: view

Pathways & Interactions for ZNF329 Gene

PathCards logo

SuperPathways for ZNF329 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF329 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF329: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF329 Gene

Drugs & Compounds for ZNF329 Gene

No Compound Related Data Available

Transcripts for ZNF329 Gene

mRNA/cDNA for ZNF329 Gene

1 REFSEQ mRNAs :
6 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF329

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF329 Gene

No ASD Table

Relevant External Links for ZNF329 Gene

GeneLoc Exon Structure for
ZNF329

Expression for ZNF329 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF329 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF329 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF329 Gene



Protein tissue co-expression partners for ZNF329 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF329

SOURCE GeneReport for Unigene cluster for ZNF329 Gene:

Hs.458377

Evidence on tissue expression from TISSUES for ZNF329 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF329: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF329 Gene

Orthologs for ZNF329 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF329 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF329 31 30
  • 99.57 (n)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF329 31
  • 86 (a)
OneToOne
LOC100856172 30
  • 84.04 (n)
rat
(Rattus norvegicus)
Mammalia Zfp329 30
  • 82.84 (n)
mouse
(Mus musculus)
Mammalia Zfp329 17 31 30
  • 82.63 (n)
cow
(Bos Taurus)
Mammalia ZNF329 31 30
  • 79.56 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 55 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 54 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 31
  • 44 (a)
OneToMany
Species where no ortholog for ZNF329 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF329 Gene

ENSEMBL:
Gene Tree for ZNF329 (if available)
TreeFam:
Gene Tree for ZNF329 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZNF329: view image

Paralogs for ZNF329 Gene

(502) SIMAP similar genes for ZNF329 Gene using alignment to 2 proteins:

  • ZN329_HUMAN
  • M0R136_HUMAN
genes like me logo Genes that share paralogs with ZNF329: view

Variants for ZNF329 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF329 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs2279333 - p.Ser99Asn
rs34255209 - p.Asn182Asp

Additional dbSNP identifiers (rs#s) for ZNF329 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF329 Gene

Variant ID Type Subtype PubMed ID
esv3644926 CNV loss 21293372
esv3893260 CNV gain 25118596
nsv1066059 CNV gain 25217958
nsv1116352 CNV deletion 24896259
nsv833885 CNV loss 17160897
nsv833886 CNV gain 17160897

Variation tolerance for ZNF329 Gene

Residual Variation Intolerance Score: 14.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.21; 39.82% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF329 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF329

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF329 Gene

Disorders for ZNF329 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF329 Gene - From: DISEASES

Disorder Aliases PubMed IDs
kbg syndrome
  • kbgs
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for ZNF329

genes like me logo Genes that share disorders with ZNF329: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF329 Gene

Publications for ZNF329 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  2. VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3 54
  3. The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. (PMID: 29180619) Kumar R … Vertegaal ACO (Nature communications 2017) 3 54
  4. Reconstructing directed gene regulatory network by only gene expression data. (PMID: 27556418) Zhang L … Li SC (BMC genomics 2016) 3 54
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 54

Products for ZNF329 Gene

Sources for ZNF329 Gene