Aliases for ZNF322 Gene
External Ids for ZNF322 Gene
Previous HGNC Symbols for ZNF322 Gene
Previous GeneCards Identifiers for ZNF322 Gene
ZNF322A is a member of the zinc-finger transcription factor family and may regulate transcriptional activation in MAPK (see MAPK1; MIM 176948) signaling pathways (Li et al., 2004 [PubMed 15555580]).[supplied by OMIM, Mar 2008]
GeneCards Summary for ZNF322 Gene
ZNF322 (Zinc Finger Protein 322) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is ZNF229.
UniProtKB/Swiss-Prot Summary for ZNF322 Gene
Transcriptional activator (PubMed:15555580). Important for maintenance of pluripotency in embryonic stem cells (By similarity). Binds directly to the POU5F1 distal enhancer and the NANOG proximal promoter, and enhances expression of both genes (By similarity). Can also bind to numerous other gene promoters and regulates expression of many other pluripotency factors, either directly or indirectly (By similarity). Promotes inhibition of MAPK signaling during embryonic stem cell differentiation (By similarity).