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Aliases for ZNF320 Gene

Aliases for ZNF320 Gene

  • Zinc Finger Protein 320 2 3 3 5
  • Zinc Finger Protein Like 3
  • Zinc Finger Gene 320 3
  • ZFPL 3

External Ids for ZNF320 Gene

Previous GeneCards Identifiers for ZNF320 Gene

  • GC19U990298
  • GC19M058071
  • GC19M053379
  • GC19M049706

Summaries for ZNF320 Gene

Entrez Gene Summary for ZNF320 Gene

  • ZNF320 encodes a Kruppel-like zinc finger protein. Members of this protein family are involved in activation or repression of transcription.[supplied by OMIM, Jul 2002]

GeneCards Summary for ZNF320 Gene

ZNF320 (Zinc Finger Protein 320) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ENSG00000283088.

UniProtKB/Swiss-Prot for ZNF320 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF320 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF320 Gene

Genomics for ZNF320 Gene

GeneHancer (GH) Regulatory Elements for ZNF320 Gene

Promoters and enhancers for ZNF320 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J052896 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 695 +0.2 238 2.8 HDGF PKNOX1 ATF1 SMAD1 ARNT SIN3A POLR2B SP3 NCOA1 ZNF518A ZNF320 ZNF468 ENSG00000283088
GH19J052879 Promoter 0.5 EPDnew 650.4 +17.8 17776 0.1 ZNF320 ENSG00000283695 ZNF468
GH19J053517 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 18.2 -621.9 -621921 4.8 PKNOX1 SMAD1 ARNT ARID4B SIN3A YY1 ZNF766 E2F8 ZNF143 KLF13 ZNF331 ZNF137P LENG8 ZNF525 LENG8-AS1 ZNF808 PRPF31 CNOT3 ZNF160 ZNF701
GH19J053878 Promoter/Enhancer 1.7 Ensembl ENCODE dbSUPER 9.9 -981.8 -981816 1.4 ATF1 ARID4B SIN3A GLI4 ZNF2 ZBTB7B ZNF48 ETS1 SLC30A9 ELK1 PRKCG ERVV-2 LOC204800 BIRC8 FAM90A28P VN1R4 ENSG00000269758 VN1R6P ZNF525 LENG8-AS1
GH19J052856 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE 7.2 +40.0 40004 1.8 HDAC1 ELF3 ATF1 TAF9B ARID4B SIN3A ZNF48 ZNF335 POLR2B EGR1 ZNF468 ZNF28 ZNF320 GC19M052864
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZNF320 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF320 gene promoter:
  • Ik-1

Genomic Locations for ZNF320 Gene

Genomic Locations for ZNF320 Gene
33,904 bases
Minus strand
33,904 bases
Minus strand

Genomic View for ZNF320 Gene

Genes around ZNF320 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF320 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF320 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF320 Gene

Proteins for ZNF320 Gene

  • Protein details for ZNF320 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 320
    Protein Accession:
    Secondary Accessions:
    • Q8NDR6

    Protein attributes for ZNF320 Gene

    509 amino acids
    Molecular mass:
    59326 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF320 Gene

Post-translational modifications for ZNF320 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF320 Gene

Domains & Families for ZNF320 Gene

Gene Families for ZNF320 Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF320 Gene

Suggested Antigen Peptide Sequences for ZNF320 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF320: view

Function for ZNF320 Gene

Molecular function for ZNF320 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF320 Gene

Gene Ontology (GO) - Molecular Function for ZNF320 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISA --
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF320: view
genes like me logo Genes that share phenotypes with ZNF320: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF320

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF320 Gene

Localization for ZNF320 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF320 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF320 gene
Compartment Confidence
nucleus 5
cytosol 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytoplasmic bodies (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF320 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF320: view

Pathways & Interactions for ZNF320 Gene

SuperPathways for ZNF320 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF320: view

Pathways by source for ZNF320 Gene

2 Reactome pathways for ZNF320 Gene

Gene Ontology (GO) - Biological Process for ZNF320 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZNF320: view

No data available for SIGNOR curated interactions for ZNF320 Gene

Drugs & Compounds for ZNF320 Gene

No Compound Related Data Available

Transcripts for ZNF320 Gene

Unigene Clusters for ZNF320 Gene

Zinc finger protein 320:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF320

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF320 Gene

No ASD Table

Relevant External Links for ZNF320 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF320 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF320 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF320 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF320 Gene:


SOURCE GeneReport for Unigene cluster for ZNF320 Gene:


mRNA Expression by UniProt/SwissProt for ZNF320 Gene:

Tissue specificity: Expressed at high levels in placenta, pancreas, kidney and heart, and at lower levels in liver, skeletal muscle and brain.

Evidence on tissue expression from TISSUES for ZNF320 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF320: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF320 Gene

Orthologs for ZNF320 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF320 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF320 34 33
  • 98.95 (n)
(Canis familiaris)
Mammalia -- 34
  • 46 (a)
(Bos Taurus)
Mammalia -- 34
  • 37 (a)
Species where no ortholog for ZNF320 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF320 Gene

Gene Tree for ZNF320 (if available)
Gene Tree for ZNF320 (if available)

Paralogs for ZNF320 Gene

(510) SIMAP similar genes for ZNF320 Gene using alignment to 7 proteins:

  • ZN320_HUMAN
  • M0QX96_HUMAN
  • M0R0Z8_HUMAN
  • M0R1K6_HUMAN
  • M0R2L4_HUMAN
  • M0R2Z6_HUMAN Pseudogenes for ZNF320 Gene

genes like me logo Genes that share paralogs with ZNF320: view

Variants for ZNF320 Gene

Sequence variations from dbSNP and Humsavar for ZNF320 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000047732 -- 52,899,683(-) G/A upstream_transcript_variant
rs1000188425 -- 52,894,366(-) AGAG/AG genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000220927 -- 52,894,618(-) A/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000523924 -- 52,895,805(-) G/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000555241 -- 52,896,098(-) T/C genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF320 Gene

Variant ID Type Subtype PubMed ID
esv2678383 CNV deletion 23128226
esv2718786 CNV deletion 23290073
esv2718787 CNV deletion 23290073
esv2718796 CNV deletion 23290073
esv2718799 CNV deletion 23290073
esv2718803 CNV deletion 23290073
esv2718804 CNV deletion 23290073
esv3644726 CNV loss 21293372
esv3644727 CNV gain 21293372
esv3644728 CNV loss 21293372
esv3893234 CNV gain 25118596
nsv1057118 CNV gain 25217958
nsv1060163 CNV loss 25217958
nsv1064234 CNV gain 25217958
nsv1066098 CNV loss 25217958
nsv1066762 CNV gain 25217958
nsv1078889 OTHER inversion 25765185
nsv1140479 CNV deletion 24896259
nsv458747 CNV gain 19166990
nsv458752 CNV loss 19166990
nsv524151 CNV gain 19592680
nsv525329 CNV loss 19592680
nsv580030 CNV gain 21841781
nsv580034 CNV gain 21841781
nsv580045 CNV loss 21841781
nsv833875 CNV loss 17160897
nsv961240 CNV duplication 23825009

Variation tolerance for ZNF320 Gene

Residual Variation Intolerance Score: 64.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.41; 27.73% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF320 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF320 Gene

Disorders for ZNF320 Gene


  • Note=A chromosomal aberration involving ZNF320 is found in a form of glioblastoma. Translocation t(10;19)(q26;q13.3) with BRWD2/WDR11. {ECO:0000269 PubMed:11536051}.

Additional Disease Information for ZNF320

No disorders were found for ZNF320 Gene.

No data available for MalaCards and Genatlas for ZNF320 Gene

Publications for ZNF320 Gene

  1. A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells. (PMID: 11536051) Chernova OB … Cowell JK (Oncogene 2001) 2 3 4 58
  2. Genome-wide association study of Alzheimer's disease with psychotic symptoms. (PMID: 22005930) Hollingworth P … Williams J (Molecular psychiatry 2012) 3 44 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  5. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 58

Products for ZNF320 Gene

Sources for ZNF320 Gene

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