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Aliases for ZNF319 Gene

Aliases for ZNF319 Gene

  • Zinc Finger Protein 319 2 3 5
  • KIAA1388 4
  • ZFP319 3

External Ids for ZNF319 Gene

Previous GeneCards Identifiers for ZNF319 Gene

  • GC16M058112
  • GC16M057763
  • GC16M057803
  • GC16M056586
  • GC16M043895

Summaries for ZNF319 Gene

GeneCards Summary for ZNF319 Gene

ZNF319 (Zinc Finger Protein 319) is a Protein Coding gene.

UniProtKB/Swiss-Prot for ZNF319 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF319 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF319 Gene

Genomics for ZNF319 Gene

GeneHancer (GH) Regulatory Elements for ZNF319 Gene

Promoters and enhancers for ZNF319 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I057998 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 +0.5 470 4.2 HDGF ARID4B SIN3A DMAP1 YY1 POLR2B ZNF143 SP3 SP5 MXD4 ZNF319 USB1 TEPP
GH16I057666 Promoter/Enhancer 2 EPDnew FANTOM5 Ensembl ENCODE 14 +332.3 332267 4 HDGF PKNOX1 MLX ARID4B DMAP1 ZNF766 ZNF143 ZNF263 ZHX2 MXD4 ADGRG3 DRC7 RSPRY1 ZNF319 SETD6 ENSG00000261114 ENSG00000260467 FAM192A USB1
GH16I058021 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 4.6 -24.8 -24776 7.1 PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 YY1 SLC30A9 MMP15 TEPP CFAP20 CNGB1 CSNK2A2 ZNF319 GC16P058028
GH16I057992 Enhancer 0.8 ENCODE 6.2 +6.3 6297 3.9 HDGF HDAC1 PKNOX1 RB1 ARID4B SIN3A ZBTB40 RAD21 ARID2 ATF7 TEPP ZNF319 PIR35383 GC16M057997 CNGB1
GH16I057528 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 2.3 +471.1 471052 4.1 HDGF ELF3 PKNOX1 ARID4B SIN3A ZBTB40 DNMT3B ZNF48 TCF12 EGR1 ADGRG5 CCDC102A DOK4 NUP93 ZNF319 PIR39147
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF319 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF319 gene promoter:

Genomic Locations for ZNF319 Gene

Genomic Locations for ZNF319 Gene
chr16:57,994,668-58,000,684
(GRCh38/hg38)
Size:
6,017 bases
Orientation:
Minus strand
chr16:58,028,572-58,034,357
(GRCh37/hg19)

Genomic View for ZNF319 Gene

Genes around ZNF319 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF319 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF319 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF319 Gene

Proteins for ZNF319 Gene

  • Protein details for ZNF319 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P2F9-ZN319_HUMAN
    Recommended name:
    Zinc finger protein 319
    Protein Accession:
    Q9P2F9
    Secondary Accessions:
    • Q52LH8

    Protein attributes for ZNF319 Gene

    Size:
    582 amino acids
    Molecular mass:
    65547 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA92626.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF319 Gene

Post-translational modifications for ZNF319 Gene

Other Protein References for ZNF319 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF319 Gene

Domains & Families for ZNF319 Gene

Gene Families for ZNF319 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF319 Gene

Suggested Antigen Peptide Sequences for ZNF319 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9P2F9

UniProtKB/Swiss-Prot:

ZN319_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF319: view

Function for ZNF319 Gene

Molecular function for ZNF319 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF319 Gene

Gene Ontology (GO) - Molecular Function for ZNF319 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF319: view
genes like me logo Genes that share phenotypes with ZNF319: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF319 Gene

Localization for ZNF319 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF319 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF319 gene
Compartment Confidence
nucleus 5

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF319 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF319: view

Pathways & Interactions for ZNF319 Gene

SuperPathways for ZNF319 Gene

No Data Available

Interacting Proteins for ZNF319 Gene

Gene Ontology (GO) - Biological Process for ZNF319 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF319: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF319 Gene

Drugs & Compounds for ZNF319 Gene

No Compound Related Data Available

Transcripts for ZNF319 Gene

mRNA/cDNA for ZNF319 Gene

Unigene Clusters for ZNF319 Gene

Zinc finger protein 319:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF319 Gene

No ASD Table

Relevant External Links for ZNF319 Gene

GeneLoc Exon Structure for
ZNF319
ECgene alternative splicing isoforms for
ZNF319

Expression for ZNF319 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF319 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF319 Gene

This gene is overexpressed in Whole Blood (x4.4).

Protein differential expression in normal tissues from HIPED for ZNF319 Gene

This gene is overexpressed in Heart (64.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF319 Gene



Protein tissue co-expression partners for ZNF319 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF319 Gene:

ZNF319

SOURCE GeneReport for Unigene cluster for ZNF319 Gene:

Hs.129268

Evidence on tissue expression from TISSUES for ZNF319 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ZNF319: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF319 Gene

Orthologs for ZNF319 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF319 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF319 33 34
  • 98.8 (n)
cow
(Bos Taurus)
Mammalia ZNF319 33 34
  • 90.34 (n)
dog
(Canis familiaris)
Mammalia ZNF319 33 34
  • 90.21 (n)
rat
(Rattus norvegicus)
Mammalia Zfp319 33
  • 88.41 (n)
mouse
(Mus musculus)
Mammalia Zfp319 33 16 34
  • 88.35 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF319 34
  • 85 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF319 33 34
  • 84.39 (n)
lizard
(Anolis carolinensis)
Reptilia ZNF319 34
  • 74 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia znf319 33
  • 70.7 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.26112 33
zebrafish
(Danio rerio)
Actinopterygii znf319 33 34
  • 68.55 (n)
AL929115.2 34
  • 66 (a)
OneToMany
Dr.10407 33
fruit fly
(Drosophila melanogaster)
Insecta crol 34
  • 18 (a)
OneToMany
Species where no ortholog for ZNF319 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF319 Gene

ENSEMBL:
Gene Tree for ZNF319 (if available)
TreeFam:
Gene Tree for ZNF319 (if available)

Paralogs for ZNF319 Gene

(287) SIMAP similar genes for ZNF319 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF319: view

No data available for Paralogs for ZNF319 Gene

Variants for ZNF319 Gene

Sequence variations from dbSNP and Humsavar for ZNF319 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs137853973 not-provided, Poikiloderma with neutropenia 58,002,623(-) G/A upstream_transcript_variant
rs786205051 pathogenic, Poikiloderma with neutropenia 58,002,558(-) CC/C upstream_transcript_variant
rs3743559 benign, not specified 58,001,525(-) C/A/G upstream_transcript_variant
rs1000234762 -- 57,999,466(-) C/T intron_variant
rs1000461198 -- 58,001,461(-) C/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF319 Gene

Variant ID Type Subtype PubMed ID
nsv572759 CNV loss 21841781
nsv1816 CNV deletion 18451855
nsv1063386 CNV gain 25217958

Variation tolerance for ZNF319 Gene

Residual Variation Intolerance Score: 20.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.90; 35.49% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF319 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF319

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF319 Gene

Disorders for ZNF319 Gene

Additional Disease Information for ZNF319

No disorders were found for ZNF319 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF319 Gene

Publications for ZNF319 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 2 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Overexpression of a novel zinc-finger protein induces apoptosis in NIH3T3 fibroblasts. (PMID: 11161788) Laub F … Ramirez F (Genomics 2000) 2 3 58
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  5. System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability. (PMID: 25755297) Xiao Z … Vertegaal AC (Molecular & cellular proteomics : MCP 2015) 4 58

Products for ZNF319 Gene

Sources for ZNF319 Gene

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