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Aliases for ZNF285 Gene

Aliases for ZNF285 Gene

  • Zinc Finger Protein 285 2 3 5
  • Zinc Finger Protein 285A 2 3 4
  • ZNF285A 3 4

External Ids for ZNF285 Gene

Previous HGNC Symbols for ZNF285 Gene

  • ZNF285A

Previous GeneCards Identifiers for ZNF285 Gene

  • GC00U990660
  • GC19U900206
  • GC19M049578
  • GC19M044886
  • GC19M041321

Summaries for ZNF285 Gene

GeneCards Summary for ZNF285 Gene

ZNF285 (Zinc Finger Protein 285) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF112.

UniProtKB/Swiss-Prot for ZNF285 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF285 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF285 Gene

Genomics for ZNF285 Gene

GeneHancer (GH) Regulatory Elements for ZNF285 Gene

Promoters and enhancers for ZNF285 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I044400 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 590.4 +0.1 108 1.4 ATF1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ETS1 ZNF143 SP3 ZNF285 ENSG00000267173 ZNF229 ZNF180 GC19P044381 ENSG00000267188
GH19I043773 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 56.3 +621.7 621709 12.4 YBX1 ZNF416 ZNF143 ZNF263 SP3 ZFP41 MEF2D ZNF610 ZNF585B GLIS1 KCNN4 ZNF180 ZNF45 ZNF225 ZNF224 ZNF284 ZNF227 ZNF283 ZNF223 ZNF576
GH19I044844 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 51.4 -446.4 -446403 7.3 YBX1 DMAP1 YY1 ZNF213 E2F8 ZNF416 ZNF143 MCM3 SP3 ZNF610 NECTIN2 GC19P044850 ZNF180 ZNF45 ZNF225 CLASRP ZNF224 ZNF234 ZNF284 FBXO46
GH19I044259 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 61.9 +141.6 141579 1.4 HDGF PKNOX1 FOXA2 ARID4B SIN3A FEZF1 DMAP1 YBX1 ZNF2 ZBTB7B ZNF233 ZNF45 ZNF180 ZNF225 ZNF224 ZNF284 ZNF227 ZNF234 ZNF235 CLASRP
GH19I044111 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE 39 +288.6 288610 2.8 PKNOX1 FOXA2 ARNT ARID4B SIN3A ZNF2 YY1 POLR2B ZNF766 ZNF213 ZNF225 LOC100379224 ZNF45 ZNF180 ZNF227 ZNF283 ZNF576 ZNF112 ZNF224 ZNF226
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF285 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF285 Gene

Genomic Locations for ZNF285 Gene
19,314 bases
Minus strand

Genomic View for ZNF285 Gene

Genes around ZNF285 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF285 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF285 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF285 Gene

Proteins for ZNF285 Gene

  • Protein details for ZNF285 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 285
    Protein Accession:
    Secondary Accessions:
    • Q17RJ3
    • Q6B0A8
    • Q6ISR5

    Protein attributes for ZNF285 Gene

    590 amino acids
    Molecular mass:
    68261 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF285 Gene


neXtProt entry for ZNF285 Gene

Post-translational modifications for ZNF285 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZNF285 Gene

Domains & Families for ZNF285 Gene

Gene Families for ZNF285 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF285 Gene

Suggested Antigen Peptide Sequences for ZNF285 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF285: view

Function for ZNF285 Gene

Molecular function for ZNF285 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF285 Gene

Gene Ontology (GO) - Molecular Function for ZNF285 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF285: view

Phenotypes for ZNF285 Gene

GenomeRNAi human phenotypes for ZNF285:
genes like me logo Genes that share phenotypes with ZNF285: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF285 Gene

Localization for ZNF285 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF285 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF285 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF285 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF285: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF285 Gene

Pathways & Interactions for ZNF285 Gene

SuperPathways for ZNF285 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF285: view

Pathways by source for ZNF285 Gene

2 Reactome pathways for ZNF285 Gene

Interacting Proteins for ZNF285 Gene

Gene Ontology (GO) - Biological Process for ZNF285 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF285: view

No data available for SIGNOR curated interactions for ZNF285 Gene

Drugs & Compounds for ZNF285 Gene

No Compound Related Data Available

Transcripts for ZNF285 Gene

Unigene Clusters for ZNF285 Gene

Zinc finger protein 285:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF285 Gene

No ASD Table

Relevant External Links for ZNF285 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF285 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF285 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF285 Gene:


SOURCE GeneReport for Unigene cluster for ZNF285 Gene:


Evidence on tissue expression from TISSUES for ZNF285 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF285: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF285 Gene

Orthologs for ZNF285 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF285 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF285 33 34
  • 98.08 (n)
(Canis familiaris)
Mammalia ZNF285 34
  • 75 (a)
Species where no ortholog for ZNF285 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF285 Gene

Gene Tree for ZNF285 (if available)
Gene Tree for ZNF285 (if available)

Paralogs for ZNF285 Gene

(515) SIMAP similar genes for ZNF285 Gene using alignment to 5 proteins: Pseudogenes for ZNF285 Gene

genes like me logo Genes that share paralogs with ZNF285: view

Variants for ZNF285 Gene

Sequence variations from dbSNP and Humsavar for ZNF285 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000085630 -- 44,390,030(-) A/G intron_variant
rs1000368948 -- 44,399,389(-) T/A intron_variant
rs1000621190 -- 44,399,793(-) T/A intron_variant
rs1000776599 -- 44,399,622(-) A/G intron_variant
rs1000814192 -- 44,394,592(-) C/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF285 Gene

Variant ID Type Subtype PubMed ID
nsv9734 CNV gain+loss 18304495
nsv960852 CNV duplication 23825009
nsv817849 CNV loss 17921354
nsv579856 CNV gain 21841781
nsv579855 CNV loss 21841781
nsv515911 CNV loss 19592680
nsv442465 CNV loss 18776908
nsv1062330 CNV loss 25217958
nsv1061350 CNV loss 25217958
nsv1055278 CNV loss 25217958
esv3644482 CNV loss 21293372
esv2763206 CNV loss 21179565
esv2758764 CNV loss 17122850
esv2663330 CNV deletion 23128226
esv25060 CNV loss 19812545
esv2421963 CNV deletion 20811451
dgv3605n100 CNV loss 25217958

Variation tolerance for ZNF285 Gene

Residual Variation Intolerance Score: 98.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 12.62; 94.53% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF285 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF285 Gene

Disorders for ZNF285 Gene

Additional Disease Information for ZNF285

No disorders were found for ZNF285 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF285 Gene

Publications for ZNF285 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. (PMID: 23049088) Meng W … Malecaze F (Investigative ophthalmology & visual science 2012) 3 58
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for ZNF285 Gene

Sources for ZNF285 Gene

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