Aliases for ZNF268 Gene
External Ids for ZNF268 Gene
Previous GeneCards Identifiers for ZNF268 Gene
GeneCards Summary for ZNF268 Gene
ZNF268 (Zinc Finger Protein 268) is a Protein Coding gene. Diseases associated with ZNF268 include Cervical Cancer and Ovarian Cancer. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF182.
UniProtKB/Swiss-Prot Summary for ZNF268 Gene
[Isoform 1]: Acts as a transcriptional repressor. Inhibits erythroid differentiation and tumor cell proliferation. Plays a role during ovarian cancer development and progression.
[Isoform 2]: Contributes to cervical carcinogenesis in part through the TNF-alpha-induced NF-kappa-B signaling pathway by interacting with the I-kappa-B-kinase (IKK) core complex.