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Aliases for ZNF26 Gene

Aliases for ZNF26 Gene

  • Zinc Finger Protein 26 2 3 5
  • Zinc Finger Protein KOX20 3 4
  • KOX20 3 4
  • Zinc Finger Protein 26 (KOX 20) 2
  • Epididymis Luminal Protein 179 3
  • HEL-179 3

External Ids for ZNF26 Gene

Previous GeneCards Identifiers for ZNF26 Gene

  • GC12P131066
  • GC12P133116
  • GC12P131825
  • GC12P131393
  • GC12P132173
  • GC12P132073
  • GC12P133563
  • GC12P130343

Summaries for ZNF26 Gene

GeneCards Summary for ZNF26 Gene

ZNF26 (Zinc Finger Protein 26) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ZNF605.

UniProtKB/Swiss-Prot for ZNF26 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF26 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF26 Gene

Genomics for ZNF26 Gene

GeneHancer (GH) Regulatory Elements for ZNF26 Gene

Promoters and enhancers for ZNF26 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I132985 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 563.3 +0.2 186 2 HDGF SMAD1 MLX ARID4B SIN3A DMAP1 ZNF2 IRF4 YY1 SLC30A9 ZNF26 ZNF140 ZNF605 ZNF268 GOLGA3 ZNF10 ZNF891 DDX51 RNU4ATAC12P
GH12I132827 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 74.4 -157.9 -157865 2.6 PKNOX1 CLOCK SMAD1 MLX ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 GOLGA3 ANKLE2 ZNF140 ZNF26 EP400 NOC4L CHFR ZNF891 POLE ZNF268
GH12I132597 Enhancer 1.2 Ensembl ENCODE 142.4 -388.0 -388034 1.8 HDGF ARNT YBX1 ZNF2 ZNF143 ZNF548 SP3 ZNF662 REST ZNF592 ZNF140 EP400 ZNF84 ZNF268 ZNF891 ZNF26 GOLGA3 ZNF605 ANKLE2 DDX51
GH12I132886 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 43.1 -98.3 -98346 3.2 HDGF PKNOX1 CLOCK SMAD1 ARID4B SIN3A DMAP1 ZNF2 YY1 CBX5 CHFR LOC101928530 ZNF140 ANKLE2 EP400 ZNF26 ZNF891 EP400P1 GOLGA3 ZNF268
GH12I133079 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 24.6 +94.3 94274 2.8 HDGF PKNOX1 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF140 PIR45490 PIR60665 GC12M133081 GC12M133080 ZNF26 EP400P1 ZNF84 GOLGA3 ZNF10
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF26 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF26 gene promoter:

Genomic Locations for ZNF26 Gene

Genomic Locations for ZNF26 Gene
chr12:132,986,348-133,032,952
(GRCh38/hg38)
Size:
46,605 bases
Orientation:
Plus strand
chr12:133,562,951-133,589,154
(GRCh37/hg19)

Genomic View for ZNF26 Gene

Genes around ZNF26 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF26 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF26 Gene

Proteins for ZNF26 Gene

  • Protein details for ZNF26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17031-ZNF26_HUMAN
    Recommended name:
    Zinc finger protein 26
    Protein Accession:
    P17031
    Secondary Accessions:
    • Q86X57
    • Q9NWL3

    Protein attributes for ZNF26 Gene

    Size:
    533 amino acids
    Molecular mass:
    61282 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH08211.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA91367.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF26 Gene

Post-translational modifications for ZNF26 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF26 Gene

Domains & Families for ZNF26 Gene

Gene Families for ZNF26 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted secreted proteins
  • Transcription factors

Protein Domains for ZNF26 Gene

Suggested Antigen Peptide Sequences for ZNF26 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P17031

UniProtKB/Swiss-Prot:

ZNF26_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF26: view

Function for ZNF26 Gene

Molecular function for ZNF26 Gene

GENATLAS Biochemistry:
zinc finger protein 26 (KOX20) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF26: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF26 Gene

Localization for ZNF26 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF26 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF26 gene
Compartment Confidence
nucleus 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Mitochondria (2)
  • Nuclear bodies (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF26: view

Pathways & Interactions for ZNF26 Gene

SuperPathways for ZNF26 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF26: view

Pathways by source for ZNF26 Gene

2 Reactome pathways for ZNF26 Gene

Gene Ontology (GO) - Biological Process for ZNF26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF26: view

No data available for SIGNOR curated interactions for ZNF26 Gene

Drugs & Compounds for ZNF26 Gene

No Compound Related Data Available

Transcripts for ZNF26 Gene

Unigene Clusters for ZNF26 Gene

Zinc finger protein 26:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF26 Gene

No ASD Table

Relevant External Links for ZNF26 Gene

GeneLoc Exon Structure for
ZNF26
ECgene alternative splicing isoforms for
ZNF26

Expression for ZNF26 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF26 Gene

Protein differential expression in normal tissues from HIPED for ZNF26 Gene

This gene is overexpressed in Skin (59.3) and Heart (9.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF26 Gene



Protein tissue co-expression partners for ZNF26 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF26 Gene:

ZNF26

SOURCE GeneReport for Unigene cluster for ZNF26 Gene:

Hs.489608
genes like me logo Genes that share expression patterns with ZNF26: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF26 Gene

Orthologs for ZNF26 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF26 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF26 33 34
  • 99.65 (n)
cow
(Bos Taurus)
Mammalia ZNF26 33
  • 87.51 (n)
dog
(Canis familiaris)
Mammalia -- 34
  • 29 (a)
ManyToMany
Species where no ortholog for ZNF26 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF26 Gene

ENSEMBL:
Gene Tree for ZNF26 (if available)
TreeFam:
Gene Tree for ZNF26 (if available)

Paralogs for ZNF26 Gene

(541) SIMAP similar genes for ZNF26 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF26: view

Variants for ZNF26 Gene

Sequence variations from dbSNP and Humsavar for ZNF26 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1000027385 -- 132,994,483(+) T/G intron_variant
rs1000054008 -- 133,014,457(+) G/A genic_downstream_transcript_variant, intron_variant
rs1000169556 -- 132,992,018(+) C/T intron_variant
rs1000403976 -- 133,014,797(+) C/T genic_downstream_transcript_variant, intron_variant
rs1000596262 -- 133,009,364(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF26 Gene

Variant ID Type Subtype PubMed ID
dgv1590n100 CNV gain 25217958
dgv1591n100 CNV gain 25217958
dgv219n27 CNV gain 19166990
dgv3059n54 CNV gain 21841781
dgv330e199 CNV deletion 23128226
dgv917n106 CNV deletion 24896259
esv2759923 CNV loss 17122850
esv2763013 CNV gain 21179565
nsv1054709 CNV loss 25217958
nsv1054933 CNV gain 25217958
nsv1071081 CNV deletion 25765185
nsv438246 CNV loss 16468122
nsv455813 CNV gain 19166990
nsv470336 CNV gain 18288195
nsv525745 CNV gain 19592680
nsv561142 CNV gain 21841781

Additional Variant Information for ZNF26 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF26

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ZNF26 Gene

Disorders for ZNF26 Gene

Additional Disease Information for ZNF26

No disorders were found for ZNF26 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF26 Gene

Publications for ZNF26 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen HJ (The New biologist 1990) 3 4 58
  4. Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus. (PMID: 25505242) Fernandez J … Arhel NJ (The Journal of biological chemistry 2015) 3 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for ZNF26 Gene

Sources for ZNF26 Gene

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