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ZNF24 (Zinc Finger Protein 24) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is ZNF396.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | IDA | 11532988 |
GO:0003676 | nucleic acid binding | IEA | -- |
GO:0003677 | DNA binding | IEA | -- |
GO:0003700 | DNA-binding transcription factor activity | IEA | -- |
GO:0005515 | protein binding | IPI | 16169070 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA,ISS | -- |
GO:0005654 | nucleoplasm | IDA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
GO:0042552 | myelination | IEA,ISS | -- |
GO:0045892 | negative regulation of transcription, DNA-templated | IDA | 10585455 |
GO:0045944 | positive regulation of transcription by RNA polymerase II | IDA | 11532988 |
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Zinc | Approved, Investigational | Pharma | 1594 |
ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | ||||||||||||||||||
SP2: | - | - | |||||||||||||||||||
SP3: | - | ||||||||||||||||||||
SP4: |
This gene was present in the common ancestor of mammals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ZNF24 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | ZNF24 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | ZNF24 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Zfp191 30 31 |
|
OneToOne | |
Zfp24 17 |
|
||||
Rat (Rattus norvegicus) |
Mammalia | Zfp191 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | ZNF24 31 |
|
OneToOne |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
nsv1059793 | CNV | gain | 25217958 |
No disorders were found for ZNF24 Gene.