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Aliases for ZNF233 Gene

Aliases for ZNF233 Gene

  • Zinc Finger Protein 233 2 3 5

External Ids for ZNF233 Gene

Previous GeneCards Identifiers for ZNF233 Gene

  • GC19U900205
  • GC19P049446
  • GC19P044754
  • GC19P041196

Summaries for ZNF233 Gene

GeneCards Summary for ZNF233 Gene

ZNF233 (Zinc Finger Protein 233) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF112.

UniProtKB/Swiss-Prot for ZNF233 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF233 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF233 Gene

Genomics for ZNF233 Gene

GeneHancer (GH) Regulatory Elements for ZNF233 Gene

Promoters and enhancers for ZNF233 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I044259 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 584.1 +0.2 152 1.4 HDGF PKNOX1 FOXA2 ARID4B SIN3A FEZF1 DMAP1 YBX1 ZNF2 ZBTB7B ZNF233 ZNF45 ZNF180 ZNF225 ZNF224 ZNF284 ZNF227 ZNF234 ZNF235 CLASRP
GH19I044211 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 24.2 -47.1 -47079 2 ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 POLR2B ZNF766 ZNF227 ZNF180 ZNF45 ZNF112 ZNF225 ENSG00000267191 ZNF283 ZNF235 ZNF224 ZNF155
GH19I044164 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 22.6 -94.6 -94630 1.8 PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B ZNF766 ZNF226 ZNF45 ZNF180 ZNF225 ZNF155 ZNF224 ZNF227 ZNF284 ZNF234 ZNF112
GH19I044206 Promoter/Enhancer 1.6 Ensembl ENCODE 23.9 -52.1 -52146 1.7 PKNOX1 ARID4B SIN3A FEZF1 ZNF2 YY1 POLR2B ZNF766 ZNF213 ZNF302 ZNF227 ZNF45 ZNF180 ZNF225 ZNF224 ZNF283 ZNF223 ZNF226 ZNF235 ZNF112
GH19I044303 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 17.4 +44.7 44669 2.2 ARID4B SIN3A DMAP1 IRF4 YY1 ZNF766 ZNF143 FOS PAF1 SP3 ZNF235 PIR37551 ZNF226 LOC100505715 ZNF285 LOC100379224 ZNF233 ENSG00000267191 ZNF225 ZNF428
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF233 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF233 gene promoter:

Genomic Locations for ZNF233 Gene

Genomic Locations for ZNF233 Gene
15,438 bases
Plus strand

Genomic View for ZNF233 Gene

Genes around ZNF233 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF233 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF233 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF233 Gene

Proteins for ZNF233 Gene

  • Protein details for ZNF233 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 233
    Protein Accession:
    Secondary Accessions:
    • B2RN78
    • B2RN79
    • Q86WL8

    Protein attributes for ZNF233 Gene

    670 amino acids
    Molecular mass:
    76861 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF233 Gene

Post-translational modifications for ZNF233 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF233 Gene

Domains & Families for ZNF233 Gene

Gene Families for ZNF233 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF233 Gene

Suggested Antigen Peptide Sequences for ZNF233 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF233: view

Function for ZNF233 Gene

Molecular function for ZNF233 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF233 Gene

Gene Ontology (GO) - Molecular Function for ZNF233 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF233: view
genes like me logo Genes that share phenotypes with ZNF233: view

miRNA for ZNF233 Gene

miRTarBase miRNAs that target ZNF233

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF233 Gene

Localization for ZNF233 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF233 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF233 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF233 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF233: view

Pathways & Interactions for ZNF233 Gene

SuperPathways for ZNF233 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF233: view

Pathways by source for ZNF233 Gene

2 Reactome pathways for ZNF233 Gene

Interacting Proteins for ZNF233 Gene

Gene Ontology (GO) - Biological Process for ZNF233 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF233: view

No data available for SIGNOR curated interactions for ZNF233 Gene

Drugs & Compounds for ZNF233 Gene

No Compound Related Data Available

Transcripts for ZNF233 Gene

Unigene Clusters for ZNF233 Gene

Zinc finger protein 233:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF233 Gene

No ASD Table

Relevant External Links for ZNF233 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF233 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF233 Gene

Protein differential expression in normal tissues from HIPED for ZNF233 Gene

This gene is overexpressed in Plasma (68.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF233 Gene

Protein tissue co-expression partners for ZNF233 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF233 Gene:


SOURCE GeneReport for Unigene cluster for ZNF233 Gene:


Evidence on tissue expression from TISSUES for ZNF233 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF233: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF233 Gene

Orthologs for ZNF233 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF233 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF233 34
  • 74 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 41 (a)
(Mus musculus)
Mammalia Zfp111 34
  • 41 (a)
(Gallus gallus)
Aves -- 34
  • 41 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 44 (a)
(Danio rerio)
Actinopterygii zgc:162972 34
  • 35 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4360 34
  • 23 (a)
(Caenorhabditis elegans)
Secernentea tag-146 34
  • 19 (a)
C27A12.2 34
  • 16 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 36 (a)
Species where no ortholog for ZNF233 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF233 Gene

Gene Tree for ZNF233 (if available)
Gene Tree for ZNF233 (if available)

Paralogs for ZNF233 Gene

(499) SIMAP similar genes for ZNF233 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with ZNF233: view

Variants for ZNF233 Gene

Sequence variations from dbSNP and Humsavar for ZNF233 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs59660444 benign, not specified 44,274,643(+) G/ 3_prime_UTR_variant, coding_sequence_variant, frameshift, genic_downstream_transcript_variant
rs1000449764 -- 44,261,267(+) C/T intron_variant
rs1000555991 -- 44,262,879(+) C/A/T intron_variant
rs1000666203 -- 44,267,118(+) A/G coding_sequence_variant, intron_variant, missense_variant
rs1000734311 -- 44,271,753(+) A/T genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF233 Gene

Variant ID Type Subtype PubMed ID
nsv521923 CNV loss 19592680

Variation tolerance for ZNF233 Gene

Residual Variation Intolerance Score: 88.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 13.76; 95.80% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF233 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF233 Gene

Disorders for ZNF233 Gene

Additional Disease Information for ZNF233

No disorders were found for ZNF233 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF233 Gene

Publications for ZNF233 Gene

  1. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PMID: 12743021) Shannon M … Stubbs L (Genome research 2003) 2 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia. (PMID: 21078624) Kahle JJ … Zoghbi HY (Human molecular genetics 2011) 3 58
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L … Andersson-Svahn H (Molecular & cellular proteomics : MCP 2008) 3 58
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58

Products for ZNF233 Gene

Sources for ZNF233 Gene

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