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Aliases for ZNF232 Gene

Aliases for ZNF232 Gene

  • Zinc Finger Protein 232 2 3 5
  • Zinc Finger And SCAN Domain-Containing Protein 11 3 4
  • ZSCAN11 3 4

External Ids for ZNF232 Gene

Previous GeneCards Identifiers for ZNF232 Gene

  • GC17M005428
  • GC17M004953
  • GC17M005209
  • GC17M004949
  • GC17M004899
  • GC17M005008

Summaries for ZNF232 Gene

GeneCards Summary for ZNF232 Gene

ZNF232 (Zinc Finger Protein 232) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ZKSCAN1.

UniProtKB/Swiss-Prot for ZNF232 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF232 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF232 Gene

Genomics for ZNF232 Gene

GeneHancer (GH) Regulatory Elements for ZNF232 Gene

Promoters and enhancers for ZNF232 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I005122 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE 550.8 +0.2 161 0.9 CTCF POLR2A CREB1 EZH2 ZNF232 GC17P005122 ZFP3 SPAG7 SCIMP USP6 PIRC90 GC17P005090
GH17I005123 Enhancer 0.5 ENCODE 550.8 +0.8 763 0.3 ZFHX2 CREB1 EZH2 EGR2 ZNF232 GC17P005122 ZFP3 USP6 GC17P005090 PIRC90
GH17I005120 Enhancer 0.3 ENCODE 550.8 +2.0 1982 1.4 MNT ZNF232 GC17P005122 ZFP3 USP6 PIRC90 GC17P005090
GH17I004133 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 40.9 +983.6 983574 12.4 HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 CYB5D2 ZZEF1 ZNF232 PELP1 MYBBP1A LOC101927979 ANKFY1 INCA1 LOC105371492 PIR51897
GH17I004965 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 44.2 +154.5 154500 5.4 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 ZNF548 SP3 SPAG7 MIR6864 MIR6865 PIR49988 ENSG00000262429 ZNF232 NUP88 MIS12 INCA1 CHRNE
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF232 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF232 gene promoter:

Genomic Locations for ZNF232 Gene

Genomic Locations for ZNF232 Gene
chr17:5,105,541-5,123,116
(GRCh38/hg38)
Size:
17,576 bases
Orientation:
Minus strand
chr17:5,008,836-5,026,411
(GRCh37/hg19)

Genomic View for ZNF232 Gene

Genes around ZNF232 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF232 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF232 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF232 Gene

Proteins for ZNF232 Gene

  • Protein details for ZNF232 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UNY5-ZN232_HUMAN
    Recommended name:
    Zinc finger protein 232
    Protein Accession:
    Q9UNY5

    Protein attributes for ZNF232 Gene

    Size:
    417 amino acids
    Molecular mass:
    47688 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH16039.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF232 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF232 Gene

Post-translational modifications for ZNF232 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF232 Gene

Domains & Families for ZNF232 Gene

Gene Families for ZNF232 Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF232 Gene

Suggested Antigen Peptide Sequences for ZNF232 Gene

Graphical View of Domain Structure for InterPro Entry

Q9UNY5

UniProtKB/Swiss-Prot:

ZN232_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF232: view

Function for ZNF232 Gene

Molecular function for ZNF232 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF232 Gene

Gene Ontology (GO) - Molecular Function for ZNF232 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IEA --
GO:0005515 protein binding IPI 16189514
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF232: view
genes like me logo Genes that share phenotypes with ZNF232: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF232 Gene

Localization for ZNF232 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF232 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF232 gene
Compartment Confidence
nucleus 5
cytosol 4

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Nucleus (3)
  • Vesicles (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF232 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005829 cytosol IDA --
GO:0043231 intracellular membrane-bounded organelle IDA --
genes like me logo Genes that share ontologies with ZNF232: view

Pathways & Interactions for ZNF232 Gene

SuperPathways for ZNF232 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF232 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF232: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF232 Gene

Drugs & Compounds for ZNF232 Gene

No Compound Related Data Available

Transcripts for ZNF232 Gene

Unigene Clusters for ZNF232 Gene

Zinc finger protein 232:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF232 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b · 9c
SP1: - - -
SP2: - - - -
SP3: - - -
SP4:
SP5: -
SP6: -
SP7:
SP8: - -
SP9: -

Relevant External Links for ZNF232 Gene

GeneLoc Exon Structure for
ZNF232
ECgene alternative splicing isoforms for
ZNF232

Expression for ZNF232 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF232 Gene

Protein differential expression in normal tissues from HIPED for ZNF232 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF232 Gene



Protein tissue co-expression partners for ZNF232 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF232 Gene:

ZNF232

SOURCE GeneReport for Unigene cluster for ZNF232 Gene:

Hs.279914

mRNA Expression by UniProt/SwissProt for ZNF232 Gene:

Q9UNY5-ZN232_HUMAN
Tissue specificity: Ubiquitous. Higher expression seen in the liver, testis and ovary.

Evidence on tissue expression from TISSUES for ZNF232 Gene

  • Eye(4)
genes like me logo Genes that share expression patterns with ZNF232: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF232 Gene

Orthologs for ZNF232 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF232 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF232 33 34
  • 99.62 (n)
dog
(Canis familiaris)
Mammalia -- 34
  • 51 (a)
OneToMany
-- 34
  • 29 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 36 (a)
ManyToMany
Species where no ortholog for ZNF232 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF232 Gene

ENSEMBL:
Gene Tree for ZNF232 (if available)
TreeFam:
Gene Tree for ZNF232 (if available)

Paralogs for ZNF232 Gene

(502) SIMAP similar genes for ZNF232 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF232: view

Variants for ZNF232 Gene

Sequence variations from dbSNP and Humsavar for ZNF232 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
VAR_035573 A colorectal cancer sample p.Ala123Val
rs1000102971 -- 5,115,688(-) T/C genic_upstream_transcript_variant, intron_variant
rs1000107274 -- 5,120,735(-) A/C genic_upstream_transcript_variant, intron_variant
rs1000164948 -- 5,118,270(-) A/G genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000177183 -- 5,114,524(-) G/A/C genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF232 Gene

Variant ID Type Subtype PubMed ID
esv25210 CNV gain 19812545
nsv574273 CNV gain 21841781

Variation tolerance for ZNF232 Gene

Residual Variation Intolerance Score: 15.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.07; 37.96% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF232 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF232

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF232 Gene

Disorders for ZNF232 Gene

Additional Disease Information for ZNF232

No disorders were found for ZNF232 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF232 Gene

Publications for ZNF232 Gene

  1. ZNF232: structure and expression analysis of a novel human C(2)H(2) zinc finger gene, member of the SCAN/LeR domain subfamily. (PMID: 11311944) Mavrogiannis LA … Moschonas NK (Biochimica et biophysica acta 2001) 2 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for ZNF232 Gene

Sources for ZNF232 Gene

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