Aliases for ZNF215 Gene
External Ids for ZNF215 Gene
Previous GeneCards Identifiers for ZNF215 Gene
This gene is imprinted in a tissue-specific manner with preferential expression in the testis, and encodes a zinc finger protein that belongs to a family of zinc finger transcription factors. The encoded protein contains an N-terminal SRE-ZBP, Ctfin51, AW-1, and Number 18 (SCAN) domain, a kruppel-associated box A (KRABA) domain, and four C-terminal zinc finger domains. This gene is located within one of three regions on chromosome 11p15 associated with Beckwith-Wiedemann syndrome, called Beckwith-Wiedemann syndrome chromosome region-2 (BWSCR2), and is thought to play a role in the etiology of this disease. [provided by RefSeq, Aug 2017]
GeneCards Summary for ZNF215 Gene
ZNF215 (Zinc Finger Protein 215) is a Protein Coding gene. Diseases associated with ZNF215 include Beckwith-Wiedemann Syndrome and Cryptorchidism, Unilateral Or Bilateral. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF483.
UniProtKB/Swiss-Prot for ZNF215 Gene
May be involved in transcriptional regulation.
Bromodomains (BRDs) are epigenetic reader domains that selectively recognize acetylated lysine residues on the tails of histone proteins, and are the only known protein modules that can target acetylated lysine residues.