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Aliases for ZNF211 Gene

Aliases for ZNF211 Gene

  • Zinc Finger Protein 211 2 3 5
  • Zinc Finger Protein C2H2-25 3 4
  • CH2H2-25 3
  • C2H2-25 3
  • ZNF-25 3

External Ids for ZNF211 Gene

Previous GeneCards Identifiers for ZNF211 Gene

  • GC19P059043
  • GC19P058598
  • GC19P062820
  • GC19P062836
  • GC19P058141
  • GC19P054456

Summaries for ZNF211 Gene

Entrez Gene Summary for ZNF211 Gene

  • This gene encodes a protein containing a Kruppel-associated box domain and multiple zinc finger domains. This protein may play a role in developmental processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

GeneCards Summary for ZNF211 Gene

ZNF211 (Zinc Finger Protein 211) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF256.

UniProtKB/Swiss-Prot for ZNF211 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF211 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF211 Gene

Genomics for ZNF211 Gene

GeneHancer (GH) Regulatory Elements for ZNF211 Gene

Promoters and enhancers for ZNF211 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I057632 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 568.5 +3.0 3021 1.8 PKNOX1 ARID4B SIN3A DMAP1 YY1 SLC30A9 POLR2B ZNF207 ZNF143 FOS ZNF211 GC19M057341 ZNF264 TRIM28 ZNF548 ZNF805 ZNF550 ZNF134 ZNF543 ZNF417
GH19I057599 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 33.5 -30.4 -30358 1.5 PKNOX1 SMAD1 ARID4B SIN3A DMAP1 YY1 E2F8 ZNF207 ZNF143 KLF13 ZNF530 ZNF606 ZNF549 ZNF135 ZNF417 ZNF132 ZNF418 ZNF446 ZNF17 LOC105372482
GH19I058325 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 23.9 +696.5 696476 3.6 CLOCK ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF416 ZSCAN22 LOC105372480 PIR44424 ZNF134 ZNF606 ZNF417 ZNF549 ZNF135 ZNF17 ZNF446
GH19I057681 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 21.5 +51.8 51751 1.6 PKNOX1 ARID4B SIN3A DMAP1 YY1 POLR2B E2F8 ZNF416 ZNF207 ZNF143 ZNF551 ENSG00000269026 GC19P057683 ZNF17 ZNF549 ZNF304 ZNF134 ZNF773 ZNF446 ZNF211
GH19I058227 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 13.4 +598.5 598536 2.3 HDGF SMAD1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B ZNF207 ZNF544 ENSG00000283515 ZNF606 LOC105372483 ZNF135 ZNF329 MZF1-AS1 ZNF417 ZNF446 LOC100128398
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF211 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF211 gene promoter:

Genomic Locations for ZNF211 Gene

Genomic Locations for ZNF211 Gene
12,385 bases
Plus strand

Genomic View for ZNF211 Gene

Genes around ZNF211 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF211 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF211 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF211 Gene

Proteins for ZNF211 Gene

  • Protein details for ZNF211 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 211
    Protein Accession:
    Secondary Accessions:
    • B4DH10
    • B4DLC9
    • B4E3C9
    • B9ZVS7
    • B9ZVW1
    • F8WDV2
    • Q05BQ7
    • Q2TAL7
    • Q59EG4
    • Q59G36
    • Q5EBL6

    Protein attributes for ZNF211 Gene

    564 amino acids
    Molecular mass:
    64535 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAA93261.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH34351.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAD93084.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF211 Gene

neXtProt entry for ZNF211 Gene

Post-translational modifications for ZNF211 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF211 Gene

Domains & Families for ZNF211 Gene

Gene Families for ZNF211 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for ZNF211 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF211: view

Function for ZNF211 Gene

Molecular function for ZNF211 Gene

GENATLAS Biochemistry:
zinc finger protein 211,C2H2 type,expressed in the brain
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF211 Gene

Gene Ontology (GO) - Molecular Function for ZNF211 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF211: view
genes like me logo Genes that share phenotypes with ZNF211: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF211 Gene

Localization for ZNF211 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF211 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF211 gene
Compartment Confidence
nucleus 5
mitochondrion 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Mitochondria (2)
  • Rods & Rings (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF211 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF211: view

Pathways & Interactions for ZNF211 Gene

SuperPathways for ZNF211 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF211: view

Pathways by source for ZNF211 Gene

2 Reactome pathways for ZNF211 Gene

Gene Ontology (GO) - Biological Process for ZNF211 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF211: view

No data available for SIGNOR curated interactions for ZNF211 Gene

Drugs & Compounds for ZNF211 Gene

No Compound Related Data Available

Transcripts for ZNF211 Gene

Unigene Clusters for ZNF211 Gene

Zinc finger protein 211:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF211 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d · 7e
SP1: - -
SP2: -
SP3: - - - - -
SP4: - - - - - - - - - -
SP5: - - - - - -
SP6: - -
SP8: - -

Relevant External Links for ZNF211 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF211 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF211 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF211 Gene:


SOURCE GeneReport for Unigene cluster for ZNF211 Gene:


Evidence on tissue expression from TISSUES for ZNF211 Gene

  • Heart(4.2)
  • Skin(4.2)
  • Nervous system(4.2)
  • Blood(4)
genes like me logo Genes that share expression patterns with ZNF211: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF211 Gene

Orthologs for ZNF211 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF211 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF211 33 34
  • 98.92 (n)
(Canis familiaris)
Mammalia ZNF211 33 34
  • 84.24 (n)
(Bos Taurus)
Mammalia LOC789996 33
  • 83.48 (n)
ZNF211 34
  • 78 (a)
fruit fly
(Drosophila melanogaster)
Insecta Cf2 35
  • 48 (a)
CG3407 35
  • 40 (a)
CG8319 35
  • 36 (a)
CG6689 35
  • 30 (a)
Species where no ortholog for ZNF211 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF211 Gene

Gene Tree for ZNF211 (if available)
Gene Tree for ZNF211 (if available)

Paralogs for ZNF211 Gene

(551) SIMAP similar genes for ZNF211 Gene using alignment to 4 proteins: Pseudogenes for ZNF211 Gene

genes like me logo Genes that share paralogs with ZNF211: view

Variants for ZNF211 Gene

Sequence variations from dbSNP and Humsavar for ZNF211 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000082868 -- 57,638,804(+) G/A intron_variant
rs1000117549 -- 57,635,062(+) A/G intron_variant
rs1000152828 -- 57,631,777(+) C/T upstream_transcript_variant
rs1000261229 -- 57,632,752(+) T/C upstream_transcript_variant
rs1000702944 -- 57,640,432(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF211 Gene

Variant ID Type Subtype PubMed ID
dgv3685n100 CNV gain 25217958
esv3575120 CNV gain 25503493
nsv580402 CNV gain 21841781

Variation tolerance for ZNF211 Gene

Residual Variation Intolerance Score: 63.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.02; 87.48% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF211 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF211 Gene

Disorders for ZNF211 Gene

Additional Disease Information for ZNF211

No disorders were found for ZNF211 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF211 Gene

Publications for ZNF211 Gene

  1. Molecular cloning and mapping of a novel developmentally regulated human C2H2-type zinc finger. (PMID: 9096115) Becker KG … Drew PD (Mammalian genome : official journal of the International Mammalian Genome Society 1997) 2 3 4 58
  2. Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain. (PMID: 7633419) Becker KG … Drew PD (Human molecular genetics 1995) 2 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PMID: 17043677) Camargo LM … Brandon NJ (Molecular psychiatry 2007) 3 58
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58

Products for ZNF211 Gene

Sources for ZNF211 Gene

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