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Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB do... See more...
Aliases for ZNF189 Gene
External Ids for ZNF189 Gene
- HGNC: 12980
- Entrez Gene: 7743
- Ensembl: ENSG00000136870
- OMIM: 603132
- UniProtKB: O75820
Previous GeneCards Identifiers for ZNF189 Gene
- GC09P094961
- GC09P095904
- GC09P097618
- GC09P099541
- GC09P101240
- GC09P103200
- GC09P104161
- GC09P073760
Summaries for ZNF189 Gene
-
Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.[supplied by OMIM, May 2010]
GeneCards Summary for ZNF189 Gene
ZNF189 (Zinc Finger Protein 189) is a Protein Coding gene. Diseases associated with ZNF189 include Cleft Palate, Isolated. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF7.
UniProtKB/Swiss-Prot Summary for ZNF189 Gene
-
May be involved in transcriptional regulation.
Additional gene information for ZNF189 Gene
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF189 Gene
Genomics for ZNF189 Gene
GeneHancer (GH) Regulatory Elements for ZNF189 Gene
Promoters and enhancers for ZNF189 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ZNF189 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the ZNF189 gene promoter:
-
- CP2
- CREB
- deltaCREB
- POU2F1
- POU2F1a
- POU3F1
Genomic Locations for ZNF189 Gene
Genomic Locations for ZNF189 Gene
- chr9:101,398,808-101,410,660
- (GRCh38/hg38)
- Size:
- 11,853 bases
- Orientation:
- Plus strand
- chr9:104,161,155-104,172,942
- (GRCh37/hg19)
- Size:
- 11,788 bases
- Orientation:
- Plus strand
Genomic View for ZNF189 Gene
Genes around ZNF189 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q31.1 by HGNC
- 9q31.1 by Entrez Gene
- 9q31.1 by Ensembl
ZNF189 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZNF189 Gene
Proteins for ZNF189 Gene
-
Protein details for ZNF189 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O75820-ZN189_HUMAN
- Recommended name:
- Zinc finger protein 189
- Protein Accession:
- O75820
- O75802
- Q5T7D7
- Q5T7D8
- Q5T7D9
- Q9UBL4
- Q9UPE9
- Q9UPF0
- Q9UPF1
Protein attributes for ZNF189 Gene
- Size:
- 626 amino acids
- Molecular mass:
- 72976 Da
- Quaternary structure:
- No Data Available
Protein Expression for ZNF189 Gene
Post-translational modifications for ZNF189 Gene
Other Protein References for ZNF189 Gene
Antibody Products
- Atlas Antibodies Anti-ZNF189 Antibody
- Creative Biolabs Mouse Anti-ZNF189 Recombinant Antibody (3C5)
- Novus Biologicals Antibodies for ZNF189
- Invitrogen Antibodies for ZNF189 (AFLGC-ZNF189)
- antibodies-online: Show 8 available ZNF189 Antibodies ranked by validation data
- Compare Top ZNF189 Antibodies
-
Quality Products:
Protein Products
- Creative Biomart Recombinant Human ZNF189 cell lysate
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ZNF189
- Origene Custom Protein Services for ZNF189
- antibodies-online: Show 2 available ZNF189 Proteins ranked by validation data
- Compare Top ZNF189 Proteins
-
Quality Products:
-
Abcam proteins for ZNF189
No data available for DME Specific Peptides for ZNF189 Gene
Domains & Families for ZNF189 Gene
Gene Families for ZNF189 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZNF189 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZNF189 Gene
- GenScript: Design optimal peptide antigens:
-
- ZNF189 protein (B7ZLK9_HUMAN)
- Zinc finger protein 189, isoform CRA_a (Q5T7D8_HUMAN)
- Zinc finger protein 189 (ZN189_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O75820- Family:
-
- Belongs to the krueppel C2H2-type zinc-finger protein family.
Function for ZNF189 Gene
Molecular function for ZNF189 Gene
- UniProtKB/Swiss-Prot Function:
- May be involved in transcriptional regulation.
- GENATLAS Biochemistry:
- zinc finger protein 189,Kruppel-like,KRAB group,ubiquitously expressed,with tissue or cell type restricted expression pattern for the splice variants four
Phenotypes From GWAS Catalog for ZNF189 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISA | -- |
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003700 | DNA-binding transcription factor activity | TAS | 9653648 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ZNF189 Gene
- GenomeRNAi human phenotypes for ZNF189:
-
- Dynamic nuclei (hole, folded or small irregular)
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Decreased viability
- no effect
- Decreased viability after sindbis virus (SIN) dsTE12Q infection
- Decreased Sindbis virus (SIN) capsid and autophagosome LC3 protein colocalization
- Decreased mitophagy mCherry-Parkin protein expression after carbonyl cyanide m-chlorphenylhydrazone (CCCP) stimulation
- Decreased homologous recombination repair frequency
- Decreased hepcidin::fluc mRNA expression
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for ZNF189
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF189
- genomics-online: gRNA clones - Search for available ZNF189 gRNA products
- Overview of 113 available ZNF189 gene related products
- Applied Biological Materials (abm): CRISPR Clones for ZNF189 - Select products 50% OFF >
- * ZNF189 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * ZNF189 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF189
miRNA for ZNF189 Gene
- miRTarBase miRNAs that target ZNF189
Targeted motifs for ZNF189 Gene
HOMER Transcription Factor Regulatory Elements motif ZNF189
- Consensus sequence: TGGAACAGMA Submotif: canonical Cell Type: HEK293 GEO ID: GSE58341
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for ZNF189
- Browse OriGene Inhibitory RNA Products For ZNF189
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF189
- genomics-online: shRNA clones - Search for available ZNF189 shRNA products
- Overview of 113 available ZNF189 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ZNF189
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF189
- Applied Biological Materials (abm): Clones for ZNF189 - Select products 50% OFF >
- * ZNF189 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * ZNF189 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Cell Line Products
-
Horizon Cell Lines for ZNF189
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models and Transcription Factor Targets for ZNF189 Gene
Localization for ZNF189 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZNF189 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytoskeleton | 2 |
| cytosol | 2 |
- Intermediate filaments (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IEA | -- |
| GO:0005634 | nucleus | IEA | -- |
Pathways & Interactions for ZNF189 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Gene Expression |
.48
|
|
| 2 | Herpes simplex virus 1 infection | ||
Pathways by source for ZNF189 Gene
2 Reactome pathways for ZNF189 Gene
1 KEGG pathway for ZNF189 Gene
Interacting Proteins for ZNF189 Gene
GPS-Prot Interaction Network for ZNF189
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | TAS | 9653648 |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
No data available for SIGNOR curated interactions for ZNF189 Gene
Drugs & Compounds for ZNF189 Gene
No Compound Related Data Available
Drug Products
- Creative Biomart Recombinant Human ZNF189 cell lysate
Transcripts for ZNF189 Gene
mRNA/cDNA for ZNF189 Gene
- (5) REFSEQ mRNAs :
- (23) Additional mRNA sequences :
- (100) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000259395 3115 bps (ENST00000259395.4)
- ENST00000339664 3021 bps (ENST00000339664.6)
- ENST00000374861 3134 bps (ENST00000374861.7)
- ENST00000615466 2316 bps (ENST00000615466.1)
CRISPR Products
-
OriGene CRISPR knockouts for ZNF189
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF189
- genomics-online: gRNA clones - Search for available ZNF189 gRNA products
- Overview of 113 available ZNF189 gene related products
- Applied Biological Materials (abm): CRISPR Clones for ZNF189 - Select products 50% OFF >
- * ZNF189 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * ZNF189 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF189
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for ZNF189
- Browse OriGene Inhibitory RNA Products For ZNF189
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF189
- genomics-online: shRNA clones - Search for available ZNF189 shRNA products
- Overview of 113 available ZNF189 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ZNF189
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF189
- Applied Biological Materials (abm): Clones for ZNF189 - Select products 50% OFF >
- * ZNF189 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * ZNF189 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | · | 6f |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - |
Expression for ZNF189 Gene
This gene is overexpressed in Neutrophil (68.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF189 Gene
NURSA nuclear receptor signaling pathways regulating expression of ZNF189 Gene:
ZNF189SOURCE GeneReport for Unigene cluster for ZNF189 Gene:
Hs.50123mRNA Expression by UniProt/SwissProt for ZNF189 Gene:
O75820-ZN189_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for ZNF189 Gene
- Nervous system(4.5)
- Bone marrow(4.1)
Primer Products
-
OriGene qPCR primer pairs for ZNF189
- genomics-online: primer clones - Search for available ZNF189 Primer products
- Overview of 113 available ZNF189 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF189 Gene
Orthologs for ZNF189 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ZNF189 33 32 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ZNF189 33 32 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | ZNF189 33 32 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Zfp189 32 |
|
||
| mouse (Mus musculus) |
Mammalia | Zfp189 17 33 32 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 33 |
|
OneToMany | |
| -- 33 |
|
OneToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | -- 33 |
|
ManyToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100489897 32 |
|
- Species where no ortholog for ZNF189 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Evolution for ZNF189 Gene
- ENSEMBL:
- Gene Tree for ZNF189 (if available)
- TreeFam:
- Gene Tree for ZNF189 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ZNF189: view image
Paralogs for ZNF189 Gene
Paralogs for ZNF189 Gene
- ZNF7 5
- ZNF568 5
- ZNF250 5
- ZNF135 5
- ZNF616 5
- ZNF728 5
- ZNF726 5
- ZNF182 5
- ZNF43 5
- ZNF33A 5
- ZNF33B 5
- ZNF571 5
- ZNF354B 5
- ZNF251 5
- ZNF45 5
- ZNF585A 5
- ZNF41 5
- ZNF879 5
- ZNF226 5
- ZNF235 5
- ZNF658 5
- ZNF229 5
- ZNF132 5
- ZNF782 5
- ZNF624 5
- ZNF605 5
- ZNF234 5
- ZNF429 5
- ZNF227 5
- ZNF814 5
- ZNF595 5
- ZNF724 5
- ZNF585B 5
- ZNF493 5
- ZNF606 5
- ZFP14 5
- ZNF841 5
- ZNF12 5
- ZNF780B 5
- ZFP28 5
- ZNF197 5
- ZNF790 5
- ZNF540 5
- ZNF23 5
- ZNF268 5
- ZNF544 5
- ZNF699 5
- ZNF780A 5
- ZNF112 5
- ZFP30 5
- ZNF470 5
- ZNF615 5
- ZNF543 5
- ZNF354C 5
- ZNF546 5
- ZNF354A 5
- ZNF317 5
- ZNF528 5
- ZNF30 5
- ZNF16 5
- ZNF254 5
- ZNF732 5
- ZNF28 5
- ZNF311 5
- ZNF436 5
- ZNF607 5
- ZNF573 5
- ZFP82 5
- ZNF836 5
- ZNF224 5
- ZNF681 5
- ZNF267 5
- ZNF676 5
- ZNF629 5
- ZNF565 5
- ZNF484 5
- ZNF74 5
- ZNF454 5
- ZNF383 5
- RBAK 5
- ZNF432 5
- ZNF534 5
- ZNF175 5
- ZNF708 5
- ZNF331 5
- ZNF93 5
- ZNF345 5
- ZNF519 5
- ZNF26 5
- ZNF85 5
- ZNF157 5
- ZNF300 5
- ZNF81 5
- ZNF630 5
- ZNF225 5
- ZNF461 5
- ZNF471 5
- ZFP3 5
- ZFP2 5
- ZNF678 5
- ZNF286A 5
- ENSG00000255104 5
- ZNF677 5
- ZNF83 5
- ZNF283 5
- ZNF483 5
- ZNF37A 5
- ENSG00000233757 5
- ZNF415 5
- ZNF835 5
- ZNF195 5
- ZNF71 5
- ZNF716 5
- ZNF623 5
- ZNF695 5
- ZNF510 5
- ZNF600 5
- ZNF221 5
- ZNF320 5
- ZSCAN10 5
- ZNF492 5
- ZNF3 5
- MZF1 5
- ZNF490 5
- ZNF90 5
- ZNF334 5
- ZNF682 5
- ZNF727 5
- ZNF260 5
- ZNF140 5
- ZNF517 5
- ZNF717 5
- ZNF286B 5
- ZNF502 5
- ZNF829 5
- ZNF460 5
- ZNF718 5
- ZNF880 5
- ZKSCAN5 5
- ZNF141 5
- ZNF117 5
- ZIM3 5
- ZNF391 5
- ZNF714 5
- ZNF2 5
- ZNF577 5
- ZNF628 5
- ZNF736 5
- ENSG00000285447 5
- ZNF486 5
- ZNF284 5
- ZNF322 5
- ZFP1 5
- ZNF713 5
- ZNF239 5
- ZNF611 5
- ZNF514 5
- ZNF789 5
- ZNF146 5
- ZNF655 5
- ZNF775 5
- ZNF506 5
- ZNF672 5
- ZNF679 5
- ZNF735 5
- ZNF501 5
- ZNF621 5
- ZNF696 5
- ENSG00000241149 5
- ZNF32 5
- GLI4 5
- ZNF121 5
- ZIM2 5
- ZNF138 5
- ENSG00000269693 5
- ENSG00000285978 5
- ENSG00000283930 5
- RBAK-RBAKDN 5
- ENSG00000267552 5
- ENSG00000267360 5
- ENSG00000283515 5
- ENSG00000267173 5
(507) SIMAP similar genes for ZNF189 Gene using alignment to 2 proteins:
- ZN189_HUMAN
- B7ZLK9_HUMAN
- kr-znf3
- ZNF78L1
- HZF36
- ZFS-4
- DKFZp666C237
- ZNF283
- ZNF501
- ZNF24
- ZSCAN16
- ZNF702P
- ZNF22
- ZNF204
- zf30
- ZNF345
- ZNF286B
- ZNF146
- HZF30
- ZFS-5
- ZFS-2
- ZSCAN23
- ZNF696
- ZNF282
- ZNF232
- ZNF213
- ZNF91
- ZNF84
- ZNF708
- ZNF271
- ZNF
- ZFS-6
- DKFZp686M04222
- ZNF664
- ZNF420
- ZNF845
- ZNF768
- ZNF347
- HZF41
- DKFZp762K012
- ZNF138
- ZNF594
- ZNF55
- ZNF323
- ZSCAN30
- ZNF721
- ZNF665
- ZNF268
- ZNF107
- DKFZp686B16128
- DKFZp313M0722
- ZNF697
- ZNF418
- ZNF485
- DKFZp686N14223
- ZSCAN12
- ZNF818P
- ZNF410
- ZNF83
- ZNF814
- ZNF808
- ZNF658B
- ZNF658
- ZNF493
- ZNF3
- ZNF226
- ZFS-1
- DKFZp686D2168
- GLI4
- ZNF331
- ZNF550
- smap-7
- ZSCAN25
- ZNF833P
- ZNF498
- ZNF85
- ZNF660
- ZNF623
- ZNF600
- ZNF572
- ZNF497
- ZNF484
- ZNF33A
- ZNF229
- Nbla00121
- ZFP41
- HZF40
- DKFZp434J0650
- ZNF566
- ZNF506
- ZSCAN29
- ZNF500
- ZNF449
- ZNF32
- ZNF883
- ZNF829
- ZNF774
- ZNF729
- ZNF648
- ZNF502
- ZNF41
- ZNF263
- ZNF23
- ZNF227
- ZNF112
- DKFZp686O111
- DKFZp686H20223
- DKFZp571N1833
- DKFZp434G1930
- ZNF137P
- PRMD9
- ZNF569
- ZNF239
- ZNF154
- ZNF28
- ZNF626
- ZNF780B
- ZSCAN21
- ZNF80
- ZNF691
- ZNF852
- ZNF678
- ZNF616
- ZNF578
- ZNF397
- ZNF391
- ZNF260
- ZNF135
- ZFP2
- ZKSCAN8
- HZF17
- ZNF782
- ZNF585B
- ZFP1
- ZNF571
- ZNF35
- ZNF208
- ZNF234
- ZNF160
- ZNF558
- PRDM9
- ZNF876P
- ZNF197
- ZSCAN20
- ZNF93
- ZNF835
- ZNF79
- ZNF662
- ZNF473
- ZNF436
- ZNF43
- ZNF429
- ZNF329
- ZNF30
- ZNF117
- MST154
- HZF14
- DKFZp686K03205
- DKFZp686J1732
- DKFZp666M039
- HZF28
- ZNF761
- ZNF286A
- ZNF850
- ZNF324B
- ZNF19
- ZNF254
- ZNF619
- ZSCAN31
- ZNF72
- ZNF250
- ZSCAN2
- ZNF844
- ZNF780A
- ZNF724P
- ZNF71
- ZNF605
- ZNF586
- ZNF546
- ZNF355P
- ZNF322
- ZNF304
- ZNF16
- ZFP62
- DKFZp686G16228
- DKFZp547L155
- ZFS-3
- HZF16
- ZNF813
- ZNF728
- ZNF709
- ZNF676
- ZNF354B
- ZKSCAN7
- DKFZp686L0787
- ZNF7
- ZNF99
- ZNF98
- ZNF92
- ZNF805
- ZNF736
- ZNF720
- ZNF680
- ZNF675
- ZNF624
- ZNF595
- ZNF567
- ZNF530
- ZNF415
- ZNF235
- ZNF184
- ZNF157
- ZFP3
- DKFZp572F2170
- DKFZp547H249
- ZNF324
- ZNF681
- ZNF841
- ZNF791
- ZNF684
- ZNF66
- ZNF471
- ZNF2
- ZNF589
- ZNF33B
- ZNF726
- ZNF354A
- ZNF257
- ZNF880
- ZNF879
- ZNF799
- ZNF790
- ZNF73
- ZNF629
- ZNF585A
- ZNF584
- ZNF551
- ZNF492
- ZNF470
- ZNF454
- ZNF34
- ZNF333
- ZFP112
- DKFZp686C13142
- ZNF544
- ZNF416
- ZNF606
- ZNF555
- ZNF528
- ZNF480
- ZNF337
- ZNF205
- ZNF182
- ZNF140
- ZNF132
- ZFP92
- ZNF667
- ZNF570
- ZNF417
- ZNF141
- ZNF568
- ZNF581
- ZNF90
- ZNF823
- ZNF816
- ZNF778
- ZNF737
- ZNF732
- ZNF649
- ZNF625
- ZNF621
- ZNF573
- ZNF565
- ZNF479
- ZNF266
- ZNF211
- ZNF14
- ZKSCAN1
- ZFP90
- RhitH
- HKR1
- GFI1
- DKFZp686O1631
- ZFP28
- ZNF557
- ZNF404
- ZNF394
- ZNF765
- ZNF701
- ZNF679
- ZNF630
- ZNF529
- ZNF383
- ZNF334
- ZNF320
- ZNF287
- ZNF175
- ZFP14
- ZKSCAN4
- ZKSCAN3
- ZNF468
- ZNF26
- ZNF514
- ZNF888
- ZNF735
- ZNF716
- ZNF70
- ZNF695
- ZNF674
- ZNF613
- ZNF607
- ZNF599
- ZNF583
- ZNF582
- ZNF549
- ZNF547
- ZNF534
- ZNF432
- ZNF431
- ZNF267
- ZNF256
- ZNF251
- ZNF225
- ZNF17
- ZNF121
- ZFP69
- MZF1
- ZNF167
- OSR2
- MYNN
- GFI1B
- DKFZp570I0164
- ZNF430
- ZNF10
- ZNF527
- ZNF74
- ZNF620
- ZNF614
- ZNF460
- ZNF442
- ZNF354C
- ZNF343
- ZNF311
- ZNF300
- ZNF181
- GD
- ZNF180
- ZNF20
- ZNF726P1
- ZSCAN26
- ZNF860
- ZNF730
- ZNF727
- ZNF615
- ZNF543
- ZNF540
- ZNF491
- ZNF483
- ZNF467
- ZNF45
- ZNF350
- ZNF25
- RBAK
- KIAA1829
- GZF1
- DKFZp686N0199
- ZNF44
- ZNF517
- ZNF165
- ZNF461
- ZNF275
- ZSCAN22
- ZNF789
- ZNF677
- ZNF670
- ZNF560
- ZNF519
- ZNF273
- ZNF224
- ZKSCAN5
- ZIM3
- ZFP95
- ZFP30
- ZNF682
- ZNF766
- ZNF587
- ZNF707
- ZNF749
- ZNF718
- ZNF714
- ZNF559
- ZNF486
- ZNF358
- ZNF264
- ZFP82
- PLAGL1
- A-328A3.4
- ZNF776
- ZNF793
- ZNF846
- ZNF836
- ZNF699
- ZNF548
- ZNF510
- ZNF441
- ZNF221
- ZNF202
- ZNF134
- ZNF124
- ZFP37
- ZNF419
- ZNF57
- ZNF382
- ZNF787
- ZNF786
- ZNF75A
- ZNF669
- ZNF878
- ZNF788
- ZNF771
- ZNF713
- ZNF611
- ZNF577
- ZNF564
- ZNF443
- ZNF37A
- ZNF319
- ZNF253
- ZNF133
- ZNF12
- ZIK1
- DKFZp434G1621
- ZNF655
- ZNF214
- ZNF561
- ZNF773
- ZNF763
- ZNF643
- ZNF554
- ZNF285A
- ZFP69B
- ZNF169
- ZNF136
- ZNF284
- ZNF81
- ZNF792
- ZNF317
- ZNF195
- ZNF100
- ZBTB47
- DKFZp686H10254
- ZNF587B
- ZNFN1A2
- ZNF155
- ZNF302
- ZNF233
- ZNF248
- ZNF562
- ZNF705A
- ZNF840
- ZNF837
- CTCFL
- ZNF671
- PRDM5
- ZNF812
- ZNF700
- ZNF596
- ZNF552
- ZNF490
- ZNF426
- ZNF425
- ZBTB41
- LOC126295
- ZSCAN9
- ZNF740
- ZNF705D
- ZNF772
- ZNF717
- ZNF672
- ZNF610
- ZNF563
- ZNF439
- ZNF285
- ZNF177
- HZF11
- ZFP64
- PLZF
- ZNF77
- ZNF525
- ZNF8
- ZNF114
- ZNF433
- REPIN1
- ZNF891
- ZF6
- ZNF101
- ZNF440
- ZSCAN10
- ZNF69
- ZNF689
- ZNF627
- ZNF230
- ZNF223
- TIPUH1
- ZNF597
- ZNF806
- ZNF764
- ZNF668
- ZNF48
Variants for ZNF189 Gene
| SNP ID | Clin | Chr 09 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000028563 | -- | 101,397,664(+) | T/A | upstream_transcript_variant | |
| rs1000189078 | -- | 101,403,253(+) | A/G | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000289701 | -- | 101,397,402(+) | T/C | upstream_transcript_variant | |
| rs1000489863 | -- | 101,402,796(+) | A/C/G | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000658529 | -- | 101,407,451(+) | ACACA/ACA | coding_sequence_variant, frameshift, intron_variant, non_coding_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2738839 | CNV | deletion | 23290073 |
| nsv478694 | CNV | novel sequence insertion | 20440878 |
Residual Variation Intolerance Score:
29.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.15;
38.99% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZNF189 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ZNF189
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF189 Gene
Disorders for ZNF189 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| cleft palate, isolated |
|
|
Search ZNF189 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ZNF189
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF189 Gene
Publications for ZNF189 Gene
- Cloning and characterization of ZNF189, a novel human Krüppel-like zinc finger gene localized to chromosome 9q22-q31. (PMID: 9653648) Odeberg J … Lundeberg J (Genomics 1998) 2 3 4 56
- Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PMID: 20634891) Jugessur A … Murray JC (PloS one 2010) 3 43 56
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 56
- DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 56
- Context-dependent Taq-polymerase-mediated nucleotide alterations, as revealed by direct sequencing of the ZNF189 gene: implications for mutation detection. (PMID: 10415338) Odeberg J … Lundeberg J (Gene 1999) 3 4 56
ExternalLinks
Products for ZNF189 Gene
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Sources for ZNF189 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
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- (65) Qiagen
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- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
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- (87) COMPARTMENTS
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- (98) GeneTex
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- (101) ProteomicsDB
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- (107) diseasecard
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