Aliases for ZNF189 Gene
External Ids for ZNF189 Gene
- HGNC: 12980
- Entrez Gene: 7743
- Ensembl: ENSG00000136870
- OMIM: 603132
- UniProtKB: O75820
Previous GeneCards Identifiers for ZNF189 Gene
- GC09P094961
- GC09P095904
- GC09P097618
- GC09P099541
- GC09P101240
- GC09P103200
- GC09P104161
- GC09P073760
Summaries for ZNF189 Gene
-
Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.[supplied by OMIM, May 2010]
GeneCards Summary for ZNF189 Gene
ZNF189 (Zinc Finger Protein 189) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA binding transcription factor activity. An important paralog of this gene is ZNF135.
UniProtKB/Swiss-Prot for ZNF189 Gene
-
May be involved in transcriptional regulation.
Additional gene information for ZNF189 Gene
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF189 Gene
Genomics for ZNF189 Gene
GeneHancer (GH) Regulatory Elements for ZNF189 Gene
Promoters and enhancers for ZNF189 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH09I101397 | Promoter/Enhancer | 2.1 | EPDnew Ensembl ENCODE | 560.1 | +0.8 | 773 | 4.4 | PKNOX1 CLOCK SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B | ZNF189 MRPL50 LOC100421197 GC09P101420 | |
| GH09I101430 | Promoter/Enhancer | 2.4 | EPDnew Ensembl ENCODE dbSUPER | 16.4 | +42.6 | 42580 | 20.9 | PKNOX1 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 | ALDOB LOC105376184 ZNF189 RNF20 TMEM246 MRPL50 TMEM246-AS1 BAAT | |
| GH09I101418 | Enhancer | 0.4 | dbSUPER | 18.2 | +20.5 | 20516 | 0.9 | ZNF766 MAX YY1 | GC09P101420 ZNF189 MRPL50 ALDOB | |
| GH09I101421 | Enhancer | 0.8 | ENCODE | 8.7 | +23.1 | 23063 | 0.9 | ELF3 FOXA2 ARID4B RAD21 THRB ZSCAN9 RARA TCF12 SLC30A9 CREM | ZNF189 ALDOB GC09P101420 | |
| GH09I101427 | Enhancer | 0.8 | ENCODE dbSUPER | 6.8 | +29.4 | 29418 | 1.3 | SMARCA5 ZNF687 CEBPG ELF1 RELA ZNF217 RCOR2 CEBPA NBN ZBTB33 | ZNF189 ALDOB GC09P101420 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ZNF189 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ZNF189 Gene
Genomic Locations for ZNF189 Gene
- chr9:101,398,808-101,410,660
- (GRCh38/hg38)
- Size:
- 11,853 bases
- Orientation:
- Plus strand
- chr9:104,161,155-104,172,942
- (GRCh37/hg19)
Genomic View for ZNF189 Gene
Genes around ZNF189 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q31.1 by Ensembl
- 9q31.1 by Entrez Gene
- 9q31.1 by HGNC
ZNF189 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZNF189 Gene
Proteins for ZNF189 Gene
-
Protein details for ZNF189 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O75820-ZN189_HUMAN
- Recommended name:
- Zinc finger protein 189
- Protein Accession:
- O75820
- O75802
- Q5T7D7
- Q5T7D8
- Q5T7D9
- Q9UBL4
- Q9UPE9
- Q9UPF0
- Q9UPF1
Protein attributes for ZNF189 Gene
- Size:
- 626 amino acids
- Molecular mass:
- 72976 Da
- Quaternary structure:
- No Data Available
Protein Expression for ZNF189 Gene
Post-translational modifications for ZNF189 Gene
Other Protein References for ZNF189 Gene
Antibody Products
- Novus Biologicals Antibodies for ZNF189
- Invitrogen Antibodies for ZNF189
- GeneTex ZNF189 antibody for ZNF189
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ZNF189
- Origene Custom Protein Services for ZNF189
- antibodies-online: Search results for 2 available ZNF189 Proteins ranked by validation data
- Compare Top ZNF189 Proteins
-
Quality Products:
- Search GeneTex for Proteins for ZNF189
-
Abcam proteins for ZNF189
Assay Products
No data available for DME Specific Peptides for ZNF189 Gene
Domains & Families for ZNF189 Gene
Gene Families for ZNF189 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZNF189 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZNF189 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O75820- Family:
-
- Belongs to the krueppel C2H2-type zinc-finger protein family.
Function for ZNF189 Gene
Molecular function for ZNF189 Gene
- GENATLAS Biochemistry:
- zinc finger protein 189,Kruppel-like,KRAB group,ubiquitously expressed,with tissue or cell type restricted expression pattern for the splice variants four
- UniProtKB/Swiss-Prot Function:
- May be involved in transcriptional regulation.
Phenotypes From GWAS Catalog for ZNF189 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003700 | DNA binding transcription factor activity | TAS | 9653648 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ZNF189 Gene
- GenomeRNAi human phenotypes for ZNF189:
-
- Decreased hepcidin::fluc mRNA expression
- Dynamic nuclei (hole, folded or small irregular)
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Decreased homologous recombination repair frequency
- Decreased viability after sindbis virus (SIN) dsTE12Q infection
- Decreased mitophagy mCherry-Parkin protein expression after carbonyl cyanide m-chlorphenylhydrazone (CCCP) stimulation
- Decreased Sindbis virus (SIN) capsid and autophagosome LC3 protein colocalization
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ZNF189
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ZNF189 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNF189 gene
- Search ViGene Biosciences for ZNF189
CRISPR Products
-
OriGene CRISPR knockouts for ZNF189
- genomics-online: gRNA clones - Search results for 65 available ZNF189 gene related products
- Overview of 65 available ZNF189 gene related products
- Applied Biological Materials CRISPR for ZNF189
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF189
- GenScript: Design CRISPR guide RNA sequences for ZNF189
miRNA for ZNF189 Gene
- miRTarBase miRNAs that target ZNF189
Targeted motifs for ZNF189 Gene
HOMER Transcription Factor Regulatory Elements motif ZNF189
- Consensus sequence: TGGAACAGMA Submotif: canonical Cell Type: HEK293 GEO ID: GSE58341
miRNA Products
- Search ViGene Biosciences for ZNF189
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for ZNF189
- Browse OriGene Inhibitory RNA Products For ZNF189
- genomics-online: shRNA clones - Search results for 65 available ZNF189 gene related products
- Overview of 65 available ZNF189 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNF189 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for ZNF189
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZNF189
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for ZNF189
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ZNF189
-
ViGene Biosciences adenoviral particle packaged cDNA for ZNF189 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ZNF189 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNF189 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models and Transcription Factor Targets for ZNF189 Gene
Localization for ZNF189 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZNF189 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytoskeleton | 3 |
| cytosol | 2 |
- Intermediate filaments (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IEA | -- |
| GO:0005634 | nucleus | IEA | -- |
Pathways & Interactions for ZNF189 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Gene Expression |
.48
|
|
Pathways by source for ZNF189 Gene
2 Reactome pathways for ZNF189 Gene
Interacting Proteins for ZNF189 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | TAS | 9653648 |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
No data available for SIGNOR curated interactions for ZNF189 Gene
Transcripts for ZNF189 Gene
mRNA/cDNA for ZNF189 Gene
- (10) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (100) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ZNF189 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ZNF189
- genomics-online: gRNA clones - Search results for 65 available ZNF189 gene related products
- Overview of 65 available ZNF189 gene related products
- Applied Biological Materials CRISPR for ZNF189
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF189
- GenScript: Design CRISPR guide RNA sequences for ZNF189
miRNA Products
- Search ViGene Biosciences for ZNF189
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for ZNF189
- Browse OriGene Inhibitory RNA Products For ZNF189
- genomics-online: shRNA clones - Search results for 65 available ZNF189 gene related products
- Overview of 65 available ZNF189 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNF189 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for ZNF189
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZNF189
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for ZNF189
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | · | 6f |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - |
Expression for ZNF189 Gene
This gene is overexpressed in Neutrophil (68.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF189 Gene
NURSA nuclear receptor signaling pathways regulating expression of ZNF189 Gene:
ZNF189SOURCE GeneReport for Unigene cluster for ZNF189 Gene:
Hs.50123mRNA Expression by UniProt/SwissProt for ZNF189 Gene:
O75820-ZN189_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for ZNF189 Gene
- Nervous system(4.5)
- Bone marrow(4.1)
Primer Products
-
OriGene qPCR primer pairs for ZNF189
- genomics-online: primer clones - Search results for 65 available ZNF189 gene related products
- Overview of 65 available ZNF189 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF189 Gene
Orthologs for ZNF189 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ZNF189 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | ZNF189 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | ZNF189 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Zfp189 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Zfp189 33 16 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
ManyToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100489897 33 |
|
- Species where no ortholog for ZNF189 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for ZNF189 Gene
Paralogs for ZNF189 Gene
(507) SIMAP similar genes for ZNF189 Gene using alignment to 2 proteins:
- kr-znf3
- ZNF78L1
- HZF36
- ZFS-4
- DKFZp666C237
- ZNF283
- ZNF501
- ZNF24
- ZSCAN16
- ZNF702P
- ZNF22
- ZNF204
- zf30
- ZNF345
- ZNF286B
- ZNF146
- HZF30
- ZFS-5
- ZFS-2
- ZSCAN23
- ZNF696
- ZNF282
- ZNF232
- ZNF213
- ZNF91
- ZNF84
- ZNF708
- ZNF271
- ZNF
- ZFS-6
- DKFZp686M04222
- ZNF664
- ZNF420
- ZNF845
- ZNF768
- ZNF347
- HZF41
- DKFZp762K012
- ZNF138
- ZNF594
- ZNF55
- ZNF323
- ZSCAN30
- ZNF721
- ZNF665
- ZNF268
- ZNF107
- DKFZp686B16128
- DKFZp313M0722
- ZNF697
- ZNF418
- ZNF485
- DKFZp686N14223
- ZSCAN12
- ZNF818P
- ZNF410
- ZNF83
- ZNF814
- ZNF808
- ZNF658B
- ZNF658
- ZNF493
- ZNF3
- ZNF226
- ZFS-1
- DKFZp686D2168
- GLI4
- ZNF331
- ZNF550
- smap-7
- ZSCAN25
- ZNF833P
- ZNF498
- ZNF85
- ZNF660
- ZNF623
- ZNF600
- ZNF572
- ZNF497
- ZNF484
- ZNF33A
- ZNF229
- Nbla00121
- ZFP41
- HZF40
- DKFZp434J0650
- ZNF566
- ZNF506
- ZSCAN29
- ZNF500
- ZNF449
- ZNF32
- ZNF883
- ZNF829
- ZNF774
- ZNF729
- ZNF648
- ZNF502
- ZNF41
- ZNF263
- ZNF23
- ZNF227
- ZNF112
- DKFZp686O111
- DKFZp686H20223
- DKFZp571N1833
- DKFZp434G1930
- ZNF137P
- PRMD9
- ZNF569
- ZNF239
- ZNF154
- ZNF28
- ZNF626
- ZNF780B
- ZSCAN21
- ZNF80
- ZNF691
- ZNF852
- ZNF678
- ZNF616
- ZNF578
- ZNF397
- ZNF391
- ZNF260
- ZNF135
- ZFP2
- ZKSCAN8
- HZF17
- ZNF782
- ZNF585B
- ZFP1
- ZNF571
- ZNF35
- ZNF208
- ZNF234
- ZNF160
- ZNF558
- PRDM9
- ZNF876P
- ZNF197
- ZSCAN20
- ZNF93
- ZNF835
- ZNF79
- ZNF662
- ZNF473
- ZNF436
- ZNF43
- ZNF429
- ZNF329
- ZNF30
- ZNF117
- MST154
- HZF14
- DKFZp686K03205
- DKFZp686J1732
- DKFZp666M039
- HZF28
- ZNF761
- ZNF286A
- ZNF850
- ZNF324B
- ZNF19
- ZNF254
- ZNF619
- ZSCAN31
- ZNF72
- ZNF250
- ZSCAN2
- ZNF844
- ZNF780A
- ZNF724P
- ZNF71
- ZNF605
- ZNF586
- ZNF546
- ZNF355P
- ZNF322
- ZNF304
- ZNF16
- ZFP62
- DKFZp686G16228
- DKFZp547L155
- ZFS-3
- HZF16
- ZNF813
- ZNF728
- ZNF709
- ZNF676
- ZNF354B
- ZKSCAN7
- DKFZp686L0787
- ZNF7
- ZNF99
- ZNF98
- ZNF92
- ZNF805
- ZNF736
- ZNF720
- ZNF680
- ZNF675
- ZNF624
- ZNF595
- ZNF567
- ZNF530
- ZNF415
- ZNF235
- ZNF184
- ZNF157
- ZFP3
- DKFZp572F2170
- DKFZp547H249
- ZNF324
- ZNF681
- ZNF841
- ZNF791
- ZNF684
- ZNF66
- ZNF471
- ZNF2
- ZNF589
- ZNF33B
- ZNF726
- ZNF354A
- ZNF257
- ZNF880
- ZNF879
- ZNF799
- ZNF790
- ZNF73
- ZNF629
- ZNF585A
- ZNF584
- ZNF551
- ZNF492
- ZNF470
- ZNF454
- ZNF34
- ZNF333
- ZFP112
- DKFZp686C13142
- ZNF544
- ZNF416
- ZNF606
- ZNF555
- ZNF528
- ZNF480
- ZNF337
- ZNF205
- ZNF182
- ZNF140
- ZNF132
- ZFP92
- ZNF667
- ZNF570
- ZNF417
- ZNF141
- ZNF568
- ZNF581
- ZNF90
- ZNF823
- ZNF816
- ZNF778
- ZNF737
- ZNF732
- ZNF649
- ZNF625
- ZNF621
- ZNF573
- ZNF565
- ZNF479
- ZNF266
- ZNF211
- ZNF14
- ZKSCAN1
- ZFP90
- RhitH
- HKR1
- GFI1
- DKFZp686O1631
- ZFP28
- ZNF557
- ZNF404
- ZNF394
- ZNF765
- ZNF701
- ZNF679
- ZNF630
- ZNF529
- ZNF383
- ZNF334
- ZNF320
- ZNF287
- ZNF175
- ZFP14
- ZKSCAN4
- ZKSCAN3
- ZNF468
- ZNF26
- ZNF514
- ZNF888
- ZNF735
- ZNF716
- ZNF70
- ZNF695
- ZNF674
- ZNF613
- ZNF607
- ZNF599
- ZNF583
- ZNF582
- ZNF549
- ZNF547
- ZNF534
- ZNF432
- ZNF431
- ZNF267
- ZNF256
- ZNF251
- ZNF225
- ZNF17
- ZNF121
- ZFP69
- MZF1
- ZNF167
- OSR2
- MYNN
- GFI1B
- DKFZp570I0164
- ZNF430
- ZNF10
- ZNF527
- ZNF74
- ZNF620
- ZNF614
- ZNF460
- ZNF442
- ZNF354C
- ZNF343
- ZNF311
- ZNF300
- ZNF181
- GD
- ZNF180
- ZNF20
- ZNF726P1
- ZSCAN26
- ZNF860
- ZNF730
- ZNF727
- ZNF615
- ZNF543
- ZNF540
- ZNF491
- ZNF483
- ZNF467
- ZNF45
- ZNF350
- ZNF25
- RBAK
- KIAA1829
- GZF1
- DKFZp686N0199
- ZNF44
- ZNF517
- ZNF165
- ZNF461
- ZNF275
- ZSCAN22
- ZNF789
- ZNF677
- ZNF670
- ZNF560
- ZNF519
- ZNF273
- ZNF224
- ZKSCAN5
- ZIM3
- ZFP95
- ZFP30
- ZNF682
- ZNF766
- ZNF587
- ZNF707
- ZNF749
- ZNF718
- ZNF714
- ZNF559
- ZNF486
- ZNF358
- ZNF264
- ZFP82
- PLAGL1
- A-328A3.4
- ZNF776
- ZNF793
- ZNF846
- ZNF836
- ZNF699
- ZNF548
- ZNF510
- ZNF441
- ZNF221
- ZNF202
- ZNF134
- ZNF124
- ZFP37
- ZNF419
- ZNF57
- ZNF382
- ZNF787
- ZNF786
- ZNF75A
- ZNF669
- ZNF878
- ZNF788
- ZNF771
- ZNF713
- ZNF611
- ZNF577
- ZNF564
- ZNF443
- ZNF37A
- ZNF319
- ZNF253
- ZNF133
- ZNF12
- ZIK1
- DKFZp434G1621
- ZNF655
- ZNF214
- ZNF561
- ZNF773
- ZNF763
- ZNF643
- ZNF554
- ZNF285A
- ZFP69B
- ZNF169
- ZNF136
- ZNF284
- ZNF81
- ZNF792
- ZNF317
- ZNF195
- ZNF100
- ZBTB47
- DKFZp686H10254
- ZNF587B
- ZNFN1A2
- ZNF155
- ZNF302
- ZNF233
- ZNF248
- ZNF562
- ZNF705A
- ZNF840
- ZNF837
- CTCFL
- ZNF671
- PRDM5
- ZNF812
- ZNF700
- ZNF596
- ZNF552
- ZNF490
- ZNF426
- ZNF425
- ZBTB41
- LOC126295
- ZSCAN9
- ZNF740
- ZNF705D
- ZNF772
- ZNF717
- ZNF672
- ZNF610
- ZNF563
- ZNF439
- ZNF285
- ZNF177
- HZF11
- ZFP64
- PLZF
- ZNF77
- ZNF525
- ZNF8
- ZNF114
- ZNF433
- REPIN1
- ZNF891
- ZF6
- ZNF101
- ZNF440
- ZSCAN10
- ZNF69
- ZNF689
- ZNF627
- ZNF230
- ZNF223
- TIPUH1
- ZNF597
- ZNF806
- ZNF764
- ZNF668
- ZNF48
Variants for ZNF189 Gene
| SNP ID | Clin | Chr 09 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000028563 | -- | 101,397,664(+) | T/A | upstream_transcript_variant | |
| rs1000189078 | -- | 101,403,253(+) | A/G | genic_upstream_transcript_variant, intron_variant | |
| rs1000289701 | -- | 101,397,402(+) | T/C | upstream_transcript_variant | |
| rs1000489863 | -- | 101,402,796(+) | A/G | genic_upstream_transcript_variant, intron_variant | |
| rs1000658529 | -- | 101,407,451(+) | ACACA/ACA | coding_sequence_variant, frameshift, intron_variant, non_coding_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2738839 | CNV | deletion | 23290073 |
| nsv478694 | CNV | novel sequence insertion | 20440878 |
Residual Variation Intolerance Score:
29.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.15;
38.99% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZNF189 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ZNF189
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF189 Gene
Disorders for ZNF189 Gene
Additional Disease Information for ZNF189
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for ZNF189 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF189 Gene
Publications for ZNF189 Gene
- Cloning and characterization of ZNF189, a novel human Krüppel-like zinc finger gene localized to chromosome 9q22-q31. (PMID: 9653648) Odeberg J … Lundeberg J (Genomics 1998) 2 3 4 58
- Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PMID: 20634891) Jugessur A … Murray JC (PloS one 2010) 3 44 58
- DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Context-dependent Taq-polymerase-mediated nucleotide alterations, as revealed by direct sequencing of the ZNF189 gene: implications for mutation detection. (PMID: 10415338) Odeberg J … Lundeberg J (Gene 1999) 3 4 58
Products for ZNF189 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ZNF189
- Origene Custom Protein Services for ZNF189
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF189
- Browse OriGene Inhibitory RNA Products For ZNF189
- OriGene qPCR primer pairs for ZNF189
- OriGene CRISPR knockouts for ZNF189
- OriGene ORF clones in human for ZNF189
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ZNF189
- GenScript: Next-day shipping of latest version cDNA ORF clones for ZNF189 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for ZNF189
- GenScript Custom Assay Services for ZNF189
- GenScript Custom overexpressing Cell Line Services for ZNF189
- GenScript: Design CRISPR guide RNA sequences for ZNF189
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ZNF189
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for ZNF189
- Novus Biologicals lysates and proteins for ZNF189
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam proteins for ZNF189
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for ZNF189
- VectorBuilder custom plasmid, inducible vectors for ZNF189
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZNF189
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 8 available ZNF189 Antibodies ranked by validation data
- Compare Top ZNF189 Antibodies
- Quality Products:
- antibodies-online: Search results for available ZNF189 related products ranked by validation data
- antibodies-online: Search results for 2 available ZNF189 Proteins ranked by validation data
- Compare Top ZNF189 Proteins
- Quality Products:
- GeneTex ZNF189 antibody for ZNF189
- Search GeneTex for Proteins for ZNF189
- ViGene Biosciences adenoviral particle packaged cDNA for ZNF189 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ZNF189 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ZNF189 gene
- Search ViGene Biosciences for ZNF189
- Horizon Cell Lines for ZNF189
- genomics-online: cdna clones - Search results for 65 available ZNF189 gene related products
- Overview of 65 available ZNF189 gene related products
- orf clones - Search results for 65 available ZNF189 gene related products
- Overview of 65 available ZNF189 gene related products
- genomics-online: gRNA clones - Search results for 65 available ZNF189 gene related products
- Overview of 65 available ZNF189 gene related products
- genomics-online: primer clones - Search results for 65 available ZNF189 gene related products
- Overview of 65 available ZNF189 gene related products
- genomics-online: shRNA clones - Search results for 65 available ZNF189 gene related products
- Overview of 65 available ZNF189 gene related products
Sources for ZNF189 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems