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Aliases for ZNF175 Gene
Aliases for ZNF175 Gene
External Ids for ZNF175 Gene
- HGNC: 12964
- NCBI Entrez Gene: 7728
- Ensembl: ENSG00000105497
- OMIM®: 601139
- UniProtKB/Swiss-Prot: Q9Y473
Previous GeneCards Identifiers for ZNF175 Gene
- GC19P052705
- GC19P052435
- GC19P056750
- GC19P056766
- GC19P052074
- GC19P048406
Summaries for ZNF175 Gene
GeneCards Summary for ZNF175 Gene
ZNF175 (Zinc Finger Protein 175) is a Protein Coding gene. Diseases associated with ZNF175 include Non-Syndromic X-Linked Intellectual Disability. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF615.
UniProtKB/Swiss-Prot Summary for ZNF175 Gene
-
Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat-induced viral LTR promoter activity.
Additional gene information for ZNF175 Gene
- HGNC (12964)
- NCBI Entrez Gene (7728)
- Ensembl (ENSG00000105497)
- OMIM® (601139)
- UniProtKB/Swiss-Prot (Q9Y473)
- Open Targets Platform(ENSG00000105497)
- Monarch Initiative
- Search for ZNF175 at DataMed
- Search for ZNF175 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF175 Gene
Genomics for ZNF175 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ZNF175 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ZNF175 on the GeneHancer Hub at the UCSC Golden Path
- Top Transcription factor binding sites by QIAGEN in the ZNF175 gene promoter:
-
- AP-2rep
- AREB6
- CP2
- GATA-1
- IRF-1
- ISGF-3
- Msx-1
- Spz1
- ZID
Genomic Locations for ZNF175 Gene
Latest Assembly
- chr19:51,571,283-51,592,510
- (GRCh38/hg38)
- Size:
- 21,228 bases
- Orientation:
- Plus strand
Previous Assembly
- chr19:52,074,536-52,095,763
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 21,228 bases
- Orientation:
- Plus strand
- chr19:52,074,551-52,092,991
- (GRCh37/hg19 by Ensembl)
- Size:
- 18,441 bases
- Orientation:
- Plus strand
Genomic View for ZNF175 Gene
Genes around ZNF175 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.41 by HGNC
- 19q13.41 by Entrez Gene
- 19q13.41 by Ensembl
ZNF175 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZNF175 Gene
Proteins for ZNF175 Gene
-
Protein details for ZNF175 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y473-ZN175_HUMAN
- Recommended name:
- Zinc finger protein 175
- Protein Accession:
- Q9Y473
- A8K9H2
Protein attributes for ZNF175 Gene
- Size:
- 711 amino acids
- Molecular mass:
- 81609 Da
- Quaternary structure:
- No Data Available
Protein Expression for ZNF175 Gene
Post-translational modifications for ZNF175 Gene
Other Protein References for ZNF175 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- Novus Biologicals Antibodies for ZNF175
-
Abcam antibodies for ZNF175
- Invitrogen Antibodies for ZNF175 (AFLGC-ZNF175)
-
Biorbyt antibodies for ZNF175
-
Custom Antibody ServicesProSci Antibodies for ZNF175
-
Santa Cruz Biotechnology (SCBT) Antibodies for ZNF175
- Sino Biological Antibodies for ZNF175
Protein products for research
-
OriGene Purified Proteins for ZNF175
- Search Origene for MassSpec and Protein Over-expression Lysates for ZNF175
- Origene Custom Protein Services for ZNF175
- antibodies-online: Show 4 available ZNF175 Proteins ranked by validation data
- Compare Top ZNF175 Proteins
-
Quality Products:
-
Abcam proteins for ZNF175
Assay products for research
No data available for DME Specific Peptides for ZNF175 Gene
Domains & Families for ZNF175 Gene
Gene Families for ZNF175 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZNF175 Gene
- InterPro:
- Blocks:
-
- C2H2-type zinc finger signature
- KRAB box
- ProtoNet:
Suggested Antigen Peptide Sequences for ZNF175 Gene
- GenScript: Design optimal peptide antigens:
-
- Zinc finger protein OTK18 (ZN175_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9Y473- Family:
-
- Belongs to the krueppel C2H2-type zinc-finger protein family.
Function for ZNF175 Gene
Molecular function for ZNF175 Gene
- UniProtKB/Swiss-Prot Function:
- Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat-induced viral LTR promoter activity.
- UniProtKB/Swiss-Prot Induction:
- By HIV-1 infection.
- GENATLAS Biochemistry:
- zinc finger protein 175,C2H2 type,ubiquitously expressed
Phenotypes From GWAS Catalog for ZNF175 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IDA | 17170456 |
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IBA | 21873635 |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | IBA | 21873635 |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific | IDA | 17170456 |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | IDA | 17170456 |
Phenotypes for ZNF175 Gene
- MGI mutant phenotypes for ZNF175:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ZNF175:
Animal Models for ZNF175 Gene
- MGI Knock Outs for ZNF175:
-
- Zfp715 Zfp715<tm1a(EUCOMM)Hmgu>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ZNF175 - Starting at $85 >
- * ZNF175 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ZNF175
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF175
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF175
miRNA for ZNF175 Gene
- miRTarBase miRNAs that target ZNF175
-
- hsa-miR-197-3p (MIRT004203)
- hsa-miR-374b-5p (MIRT016079)
- hsa-miR-335-5p (MIRT017746)
- hsa-miR-302c-5p (MIRT611974)
- hsa-miR-1229-3p (MIRT611975)
- hsa-miR-342-3p (MIRT611976)
- hsa-miR-216b-3p (MIRT611977)
- hsa-miR-1228-3p (MIRT611978)
- hsa-miR-603 (MIRT611979)
- hsa-miR-8485 (MIRT611980)
- hsa-miR-629-5p (MIRT621072)
- hsa-miR-5195-3p (MIRT649693)
- hsa-miR-5096 (MIRT649694)
- hsa-miR-6807-5p (MIRT649695)
- hsa-miR-4303 (MIRT649696)
- hsa-miR-3191-5p (MIRT649697)
- hsa-miR-27b-3p (MIRT649698)
- hsa-miR-27a-3p (MIRT649699)
- hsa-miR-513a-5p (MIRT649700)
- hsa-miR-2117 (MIRT649701)
- hsa-miR-627-3p (MIRT649702)
- hsa-miR-6751-3p (MIRT649703)
- hsa-miR-1199-5p (MIRT649704)
- hsa-miR-4653-5p (MIRT649705)
- hsa-miR-3921 (MIRT649706)
- hsa-miR-301b-5p (MIRT649707)
- hsa-miR-301a-5p (MIRT649708)
- hsa-miR-146a-3p (MIRT649709)
- hsa-miR-5584-3p (MIRT649710)
- hsa-miR-6874-3p (MIRT649711)
- hsa-miR-148b-5p (MIRT649712)
- hsa-miR-3168 (MIRT649713)
- hsa-miR-7161-3p (MIRT649714)
- hsa-miR-1343-3p (MIRT737442)
- hsa-miR-149-5p (MIRT737826)
- hsa-miR-1914-5p (MIRT738539)
- hsa-miR-2861 (MIRT739505)
- hsa-miR-330-5p (MIRT741335)
- hsa-miR-4325 (MIRT744086)
- hsa-miR-490-3p (MIRT749183)
- hsa-miR-6735-3p (MIRT754161)
- hsa-miR-6742-3p (MIRT754370)
- hsa-miR-6783-3p (MIRT755739)
- hsa-miR-6811-3p (MIRT756680)
- hsa-miR-6852-5p (MIRT757655)
- hsa-miR-939-3p (MIRT760732)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF175
- Browse OriGene Inhibitory RNA Products For ZNF175
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF175
Clone products for research
- Applied Biological Materials (abm): Clones for ZNF175 - Starting at $45 >
- * ZNF175 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ZNF175
- Addgene plasmids for ZNF175
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF175
Cell Lines for research
-
Horizon Cell Lines for ZNF175
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ZNF175 Gene
Localization for ZNF175 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZNF175 Gene
- Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| cytoskeleton | 4 |
- Cytosol (3)
- Nucleoplasm (3)
- Intermediate filaments (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | 21873635 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | IDA | -- |
| GO:0045111 | intermediate filament cytoskeleton | IDA | -- |
Pathways & Interactions for ZNF175 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Gene Expression |
.48
|
|
| 2 | Herpes simplex virus 1 infection | ||
Pathways by source for ZNF175 Gene
2 Reactome pathways for ZNF175 Gene
1 KEGG pathway for ZNF175 Gene
Interacting Proteins for ZNF175 Gene
Selected Interacting proteins:
Q9Y473-ZN175_HUMAN
ENSP00000262259
for ZNF175 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for ZNF175
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IDA | 17170456 |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006357 | regulation of transcription by RNA polymerase II | IBA | 21873635 |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | IDA | 17170456 |
| GO:0051607 | defense response to virus | IEA | -- |
No data available for SIGNOR curated interactions for ZNF175 Gene
Transcripts for ZNF175 Gene
mRNA/cDNA for ZNF175 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000262259 6552 nts (view in UCSC)
- ENST00000436511 488 nts (view in UCSC)
- ENST00000545217 1239 nts (view in UCSC)
- ENST00000596504 580 nts (view in UCSC)
- ENST00000600460 982 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ZNF175 - Starting at $85 >
- * ZNF175 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ZNF175
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF175
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF175
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF175
- Browse OriGene Inhibitory RNA Products For ZNF175
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF175
Clone products for research
- Applied Biological Materials (abm): Clones for ZNF175 - Starting at $45 >
- * ZNF175 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ZNF175
- Addgene plasmids for ZNF175
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF175
Relevant External Links for ZNF175 Gene
- GeneLoc Exon Structure for
- ZNF175
Expression for ZNF175 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF175 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF175
SOURCE GeneReport for Unigene cluster for ZNF175 Gene:
Hs.119014mRNA Expression by UniProt/SwissProt for ZNF175 Gene:
Q9Y473-ZN175_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for ZNF175 Gene
- Nervous system(4.4)
Primer products for research
-
OriGene qPCR primer pairs for ZNF175
-
OriGene qPCR primer pairs and template standards for ZNF175
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF175 Gene
Orthologs for ZNF175 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ZNF175 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | ZNF175 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | LOC100686614 30 |
|
||
| ZNF175 31 |
|
OneToOne | |||
| Mouse (Mus musculus) |
Mammalia | Zfp715 30 17 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | D19A 32 |
|
|
|
| CG6792 32 |
|
|
|||
| CG2129 32 |
|
|
- Species where no ortholog for ZNF175 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for ZNF175 Gene
- ENSEMBL:
- Gene Tree for ZNF175 (if available)
- TreeFam:
- Gene Tree for ZNF175 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ZNF175: view image
Paralogs for ZNF175 Gene
Paralogs for ZNF175 Gene
- ZNF615 5
- ZNF268 5
- ZNF658 5
- ZNF605 5
- ZNF484 5
- ZNF470 5
- RBAK 5
- ZNF41 5
- ZNF81 5
- ZNF585A 5
- ZNF585B 5
- ZNF432 5
- ZNF841 5
- ZNF836 5
- ZNF135 5
- ZNF33A 5
- ZNF33B 5
- ZNF568 5
- ZNF7 5
- ZNF23 5
- ZNF300 5
- ZNF471 5
- ZNF12 5
- ZNF182 5
- ZNF708 5
- ZNF43 5
- ZNF724 5
- ZNF571 5
- ZNF616 5
- ZFP28 5
- ZNF71 5
- ZNF595 5
- ZNF630 5
- ZNF699 5
- ZNF782 5
- ZNF189 5
- ZNF197 5
- ZNF624 5
- ZNF93 5
- ZNF85 5
- ZNF676 5
- ZNF726 5
- ZNF30 5
- ZNF790 5
- ZNF383 5
- ZNF607 5
- ZNF546 5
- ZNF227 5
- ZNF235 5
- ZNF112 5
- ZNF354A 5
- ZNF354B 5
- ZNF879 5
- ZNF528 5
- ZNF28 5
- ZNF544 5
- ZNF37A 5
- ZNF502 5
- ZNF267 5
- ZNF493 5
- ZNF728 5
- ZNF681 5
- ZNF254 5
- ZFP14 5
- ZFP82 5
- ZNF345 5
- ZNF540 5
- ZNF717 5
- ZNF780B 5
- ZNF250 5
- ZNF16 5
- ZNF283 5
- ZNF45 5
- ZNF234 5
- ZNF226 5
- ZNF229 5
- ZFP2 5
- ZNF534 5
- ZNF611 5
- ZNF600 5
- ZNF543 5
- ZNF606 5
- ZNF311 5
- ZNF629 5
- ZNF626 5
- ZNF429 5
- ZNF492 5
- ZNF565 5
- ZFP30 5
- ZNF573 5
- ZNF780A 5
- ZNF224 5
- ZNF354C 5
- ZNF331 5
- ZNF814 5
- ZNF132 5
- ZNF678 5
- ZNF732 5
- ZNF157 5
- ZNF334 5
- ZFP3 5
- ZNF510 5
- ZNF461 5
- ZNF623 5
- ZNF251 5
- ZNF221 5
- ZNF454 5
- ZNF880 5
- ZNF415 5
- ZNF716 5
- ZNF436 5
- ZNF682 5
- ZNF90 5
- ZNF260 5
- ZNF225 5
- ZNF83 5
- ZNF320 5
- ZNF460 5
- MZF1 5
- ZNF26 5
- ZNF140 5
- ZNF718 5
- ZNF195 5
- ZNF519 5
- ZSCAN10 5
- ZNF317 5
- ZNF490 5
- ZNF483 5
- ZNF286A 5
- ENSG00000255104 5
- ZKSCAN5 5
- ZNF677 5
- ZNF695 5
- ZNF74 5
- ZNF117 5
- ZNF714 5
- ZNF3 5
- ZNF2 5
- ENSG00000233757 5
- ZNF835 5
- ZNF727 5
- ENSG00000285447 5
- ZNF486 5
- ZNF577 5
- ZIM3 5
- ZNF141 5
- ZNF121 5
- ZNF679 5
- ZNF655 5
- ZNF829 5
- ZFP1 5
- ZNF628 5
- ZNF322 5
- ZNF713 5
- ZNF735 5
- ZNF506 5
- ZNF789 5
- ZNF517 5
- ZNF284 5
- ZNF672 5
- ZNF391 5
- ZNF736 5
- ZNF621 5
- ZNF775 5
- ZNF239 5
- ZNF722P 5
- ZNF275 5
- ZNF146 5
- ZNF514 5
- GLI4 5
- ZNF501 5
- ZNF696 5
- ZNF138 5
- ZIM2 5
- ZNF32 5
- ENSG00000269693 5
- RBAK-RBAKDN 5
- PLD5P1 5
- ENSG00000267360 5
- ENSG00000285978 5
- ENSG00000267552 5
- ENSG00000267173 5
- ENSG00000283515 5
(449) SIMAP similar genes for ZNF175 Gene using alignment to 5 proteins:
- ZN175_HUMAN
- F5GZI7_HUMAN
- G3V1K8_HUMAN
- L8E9H5_HUMAN
- M0R013_HUMAN
- ZNF300P1
- ZNF3
- ZNF320
- ZNF83
- ZNF670
- POM121C
- ZNF101
- ZNF649
- ZNF616
- ZNF323
- ZNF705F
- ZNF705B
- ZNF705A
- ZNF569
- ZNF283
- ZNF701
- ZFP1
- ZNF586
- ZNF585B
- ZNF780A
- ZNF525
- ZFP90
- ZNF793
- ZNF845
- ZNF420
- ZSCAN16
- ZNF844
- ZNF888
- ZNF383
- ZNF84
- ZNF721
- ZNF529
- ZNF140
- ZNF28
- ZNF250
- ZNF418
- ZNF677
- ZNF19
- ZNF705G
- ZNF655
- ZNF432
- ZNF268
- ZNF10
- ZKSCAN7
- HZF36
- ZNF707
- ZNF230
- ZNF577
- FIK
- ZNF81
- ZNF415
- ZNF776
- ZNF468
- ZNF350
- ZNF232
- ZNF846
- ZNF780B
- ZNF705E
- ZFP57
- GLI4
- ZNF519
- ZNF562
- ZNF789
- ZNF331
- ZNF695
- ZNF554
- ZNF155
- ZNF624
- ZNF224
- ZNF720
- ZNF226
- ZNF814
- ZNF664
- ZNF625-ZNF20
- ZNF552
- ZNF436
- ZNF239
- ZNF146
- ZNF124
- DKFZp686N14223
- DKFZp666M039
- ZNF615
- ZNF585A
- ZNF300
- ZNF225
- ZNF41
- ZNF630
- ZNF264
- ZNF528
- PRMD9
- ZNF32
- ZNF829
- ZNF813
- ZNF785
- ZNF674
- ZNF660
- ZNF621
- ZNF620
- ZNF25
- ZNF138
- ZNF137P
- MGC12518
- KRBOX4
- ZNF506
- ZNF836
- ZNF718
- ZNF614
- ZNF382
- ZNF267
- ZNF23
- ZNF727
- ZNF556
- ZNF790
- ZNF611
- ZNF791
- ZNF761
- ZNF7
- ZNF546
- ZNF480
- ZNF696
- ZNF501
- ZNF852
- ZNF627
- ZNF582
- ZNF502
- ZNF391
- ZNF35
- ZNF169
- HZF30
- ZNF93
- ZNF354A
- ZNF195
- ZNF596
- ZNF778
- ZNF595
- ZNF607
- ZNF248
- ZNF471
- ZFP30
- ZNF625
- ZNF419
- ZNF669
- ZNF880
- ZNF610
- ZNF559
- ZNF682
- ZNF544
- ZNF571
- ZNF461
- ZNF561
- ZNF26
- ZNF558
- ZNF394
- ZNF345
- ZNF73
- ZNF717
- ZNF619
- ZNF551
- ZNF547
- ZNF484
- ZNF347
- ZNF343
- ZNF286B
- ZNF260
- ZFP2
- ZFP14
- DKFZp434G1930
- ZKSCAN8
- PRDM9
- ZNF726
- ZNF133
- ZNF684
- ZNF485
- ZNF12
- ZNF177
- ZNF540
- ZNF454
- ZNF675
- ZNF766
- ZNF702P
- ZNF768
- ZNF738
- ZNF665
- ZNF550
- ZNF497
- ZNF460
- ZNF253
- ZNF234
- ZNF157
- ZNF135
- ZNF112
- Nbla00121
- DKFZp686L0787
- DKFZp686K03205
- DKFZp686B16128
- ZNF141
- ZNF510
- ZNF841
- ZNF613
- ZNF773
- ZNF548
- ZNF233
- HKR1
- ZNF879
- ZNF85
- ZNF235
- ZSCAN20
- ZNF883
- ZNF812
- ZNF79
- ZNF730
- ZNF728
- ZNF708
- ZNF222
- ZNF114
- ZFS-1
- HZF14
- DKFZp686G16228
- DKFZp686D2168
- LOC101928664
- ZNF223
- ZNF565
- ZNF254
- ZNF354B
- ZSCAN2
- ZNF714
- ZNF431
- ZNF417
- ZNF2
- ZNF100
- ZNF805
- ZNF724P
- ZNF208
- ZNF878
- ZNF34
- ZNF850
- ZNF788
- ZNF774
- ZNF71
- ZNF69
- ZNF557
- ZNF490
- ZNF274
- ZNF154
- ZNF107
- ZFP82
- ZKSCAN3
- ZNF816
- ZNF324B
- ZNF566
- ZNF33A
- ZNF433
- ZNF426
- ZNF709
- ZNF763
- ZNF90
- ZNF430
- ZNF527
- ZNF573
- ZNF583
- ZNF43
- ZNF570
- ZNF80
- ZNF514
- ZNF823
- ZNF808
- ZNF623
- ZNF271
- ZNF16
- MZF1
- HZF41
- DKFZp686O111
- DKFZp547L155
- ZNF66
- ZNF251
- ZNF33B
- ZNF782
- ZNF17
- ZNF181
- ZSCAN9
- ZNF263
- ZNF600
- ZNF486
- ZNF470
- ZNF442
- ZNF355P
- ZNF275
- ZNF117
- ZKSCAN4
- ZFP3
- ZNF257
- ZNF736
- ZNF732
- ZNF286A
- ZNF98
- ZNF568
- ZNF273
- ZNF517
- ZNF493
- ZSCAN29
- ZNF765
- ZNF737
- ZNF648
- ZNF629
- ZNF530
- ZNF492
- ZNF491
- ZNF443
- ZNF182
- ZNF121
- DKFZp686H20223
- DKFZp571N1833
- ZNF160
- ZNF221
- ZIK1
- ZNF91
- ZNF716
- ZNF700
- ZNF578
- ZNF302
- ZFP62
- GD
- ZNF324
- ZNF599
- ZSCAN21
- ZSCAN12
- ZNF689
- ZNF835
- ZNF74
- ZNF735
- ZNF680
- ZNF679
- ZNF678
- ZNF658B
- ZNF658
- ZNF584
- ZNF487
- ZNF404
- ZNF322
- ZNF266
- ZNF20
- ZNF184
- ZNF134
- KIAA1829
- ZNF
- OSR2
- GFI1B
- ZNF227
- ZNF587B
- ZNF317
- ZNF189
- ZNF572
- ZNF429
- ZNF304
- ZNF589
- ZNF799
- ZNF772
- ZNF729
- ZNF70
- ZNF697
- ZNF676
- ZNF605
- ZNF441
- ZNF337
- ZNF136
- TIPUH1
- HZF11
- ZNF549
- ZNF211
- ZNF180
- ZNF597
- ZNF581
- ZNF197
- ZNF77
- ZNF747
- ZNF681
- ZNF563
- ZNF534
- ZNF440
- ZNF329
- ZFP112
- ZNF165
- ZNF44
- ZNF606
- ZNF57
- ZSCAN10
- ZNF287
- ZNF92
- ZNF672
- ZNF567
- ZNF564
- ZNF45
- ZNF214
- ZNF132
- RBAK
- LOC126295
- ZNF667
- ZFP28
- ZNF439
- ZNF334
- ZNF333
- ZNF30
- ZNF229
- ZF6
- DKFZp572F2170
- ZFP37
- ZNF671
- ZNF99
- ZNF587
- ZNF285A
- ZNF560
- ZNF860
- ZNF699
- ZNF594
- ZNF473
- ZNF14
- DKFZp686J1732
- CTCFL
- ZNF416
- ZNF792
- ZNF688
- ZNF626
- ZNF543
- ZNF479
- ZNF256
- DKFZp434G1621
- ZNF285
- ZNF284
- ZNF749
- ZNF483
- ZNF467
- ZNF425
- ZNF397
- ZIM3
- LOC155060
- ZNF786
- ZNF891
- ZNF837
- ZNF555
- ZNF37A
- ZNF354C
- ZNF319
- ZNF311
- ZKSCAN5
- ZFP95
- ZNF840
- ZNF783
- ZNF668
- DKFZp686C13142
Variants for ZNF175 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF175 Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs3764548 | - |
p.Cys505Arg |
|||
| rs60097262 | - |
p.Tyr363Asn |
|||
| rs746283244 | - |
p.Lys622Arg |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2758767 | CNV | gain+loss | 17122850 |
| esv3304500 | CNV | mobile element insertion | 20981092 |
| esv3451949 | CNV | insertion | 20981092 |
| esv3644673 | CNV | loss | 21293372 |
| nsv1140251 | OTHER | inversion | 24896259 |
| nsv469584 | CNV | loss | 16826518 |
| nsv579966 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
83.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.35;
81.58% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZNF175 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ZNF175
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF175 Gene
Disorders for ZNF175 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| non-syndromic x-linked intellectual disability |
|
|
Search ZNF175 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ZNF175
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF175 Gene
Publications for ZNF175 Gene
- Molecular characterization of a putative antiretroviral transcriptional factor, OTK18. (PMID: 14688346) Carlson KA … Ikezu T (Journal of immunology (Baltimore, Md. : 1950) 2004) 3 4 23
- Isolation and mapping of a novel human gene encoding a protein containing zinc-finger structures. (PMID: 8838321) Saito H … Nakamura Y (Genomics 1996) 2 3 4
- Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis. (PMID: 22491018) Wang J … Platt A (The pharmacogenomics journal 2013) 3 41
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- YY1 and FoxD3 regulate antiretroviral zinc finger protein OTK18 promoter activation induced by HIV-1 infection. (PMID: 19034670) Buescher JL … Ikezu T (Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2009) 3 23
ExternalLinks
Products for ZNF175 Gene
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- Invitrogen Antibodies for ZNF175 (AFLGC-ZNF175)
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- Horizon Cell Lines for ZNF175
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF175
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- Biorbyt antibodies for ZNF175
Sources for ZNF175 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
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- (64) Proteopedia
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- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
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