Free for academic non-profit institutions. Other users need a Commercial license
ZNF169 (Zinc Finger Protein 169) is a Protein Coding gene. Diseases associated with ZNF169 include Malignant Essential Hypertension and Multiple Self-Healing Squamous Epithelioma. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF875.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003676 | nucleic acid binding | IEA | -- |
GO:0003677 | DNA binding | IEA | -- |
GO:0003700 | DNA-binding transcription factor activity | IBA | 21873635 |
GO:0005515 | protein binding | IPI | 25416956 |
GO:0043565 | sequence-specific DNA binding | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Gene Expression |
.48
|
|
2 | Herpes simplex virus 1 infection |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | ||||||||||||||||||
SP2: | - | ||||||||||||||||||||
SP3: | - | - | |||||||||||||||||||
SP4: | - | ||||||||||||||||||||
SP5: |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ZNF169 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | ZNF169 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | ZNF169 30 |
|
||
Rat (Rattus norvegicus) |
Mammalia | Zfp169 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Zfp169 30 17 31 |
|
OneToOne | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RSF2 33 |
|
|
SNP ID | Clinical significance and condition | Chr 09 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs12236219 | - | p.Arg381Cys | |||
rs12350212 | - | p.Gln596His | |||
rs1536690 | - | p.Pro72Leu | |||
rs34433105 | - | p.Ser152Leu | |||
rs35177967 | - | p.Glu78Lys |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv1491e214 | CNV | gain | 21293372 |
esv1152524 | CNV | insertion | 17803354 |
esv2761545 | CNV | gain | 21179565 |
esv3621113 | CNV | gain | 21293372 |
esv3621119 | CNV | gain | 21293372 |
nsv1046906 | CNV | gain | 25217958 |
nsv1112196 | CNV | deletion | 24896259 |
nsv1135294 | CNV | deletion | 24896259 |
nsv831655 | CNV | gain | 17160897 |
nsv968732 | CNV | duplication | 23825009 |
Disorder | Aliases | PubMed IDs |
---|---|---|
malignant essential hypertension |
|
|
multiple self-healing squamous epithelioma |
|
|
hereditary sensory neuropathy |
|
|