Aliases for ZNF16 Gene
External Ids for ZNF16 Gene
Previous GeneCards Identifiers for ZNF16 Gene
The protein encoded by this gene contains multiple tandem zinc finger motifs. The encoded protein is involved in the differentiation of erythroid and megakaryocytic cells. This gene is located in a cluster of related genes on chromosome 8 encoding zinc finger proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
GeneCards Summary for ZNF16 Gene
ZNF16 (Zinc Finger Protein 16) is a Protein Coding gene. Diseases associated with ZNF16 include Vasomotor Rhinitis. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is ZNF585A.
UniProtKB/Swiss-Prot Summary for ZNF16 Gene
Acts as a transcriptional activator. Promotes cell proliferation by facilitating the cell cycle phase transition from the S to G2/M phase. Involved in both the hemin- and phorbol myristate acetate (PMA)-induced erythroid and megakaryocytic differentiation, respectively. Plays also a role as an inhibitor of cell apoptosis.