Aliases for ZNF143 Gene
Aliases for ZNF143 Gene
External Ids for ZNF143 Gene
- HGNC: 12928
- Entrez Gene: 7702
- Ensembl: ENSG00000166478
- OMIM: 603433
- UniProtKB: P52747
Previous GeneCards Identifiers for ZNF143 Gene
- GC11P010122
- GC11P009522
- GC11P009446
- GC11P009439
- GC11P009153
Summaries for ZNF143 Gene
GeneCards Summary for ZNF143 Gene
ZNF143 (Zinc Finger Protein 143) is a Protein Coding gene. Diseases associated with ZNF143 include Cataract 1, Multiple Types and Split-Hand/Foot Malformation 1. Among its related pathways are RNA Polymerase III Transcription Initiation and Formation of HIV-1 elongation complex containing HIV-1 Tat. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF76.
UniProtKB/Swiss-Prot for ZNF143 Gene
-
Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8.
Additional gene information for ZNF143 Gene
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF143 Gene
Genomics for ZNF143 Gene
GeneHancer (GH) Regulatory Elements for ZNF143 Gene
Promoters and enhancers for ZNF143 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ZNF143 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ZNF143 Gene
Genomic Locations for ZNF143 Gene
- chr11:9,460,319-9,528,524
- (GRCh38/hg38)
- Size:
- 68,206 bases
- Orientation:
- Plus strand
- chr11:9,481,866-9,550,071
- (GRCh37/hg19)
Genomic View for ZNF143 Gene
Genes around ZNF143 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11p15.4 by Entrez Gene
- 11p15.4 by HGNC
- 11p15.4 by Ensembl
ZNF143 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZNF143 Gene
Proteins for ZNF143 Gene
-
Protein details for ZNF143 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P52747-ZN143_HUMAN
- Recommended name:
- Zinc finger protein 143
- Protein Accession:
- P52747
- A8K518
- B4DLY5
- E7ER34
- O75559
- Q8WUK9
Protein attributes for ZNF143 Gene
- Size:
- 638 amino acids
- Molecular mass:
- 68896 Da
- Quaternary structure:
-
- Interacts with CHD8.
- SequenceCaution:
-
- Sequence=AAC50266.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH20219.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAF83822.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for ZNF143 Gene
Post-translational modifications for ZNF143 Gene
Other Protein References for ZNF143 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for ZNF143 (ZNF143)
-
Custom Antibody ServicesOriGene Antibodies for ZNF143
- Novus Biologicals Antibodies for ZNF143
- Invitrogen Antibodies for ZNF143
- GeneTex ZNF143 Antibody for ZNF143
-
Santa Cruz Biotechnology (SCBT) Antibodies for ZNF143
Protein Products
-
OriGene Purified Proteins for ZNF143
- Search Origene for MassSpec and Protein Over-expression Lysates for ZNF143
- Origene Custom Protein Services for ZNF143
- antibodies-online: Search results for 3 available ZNF143 Proteins ranked by validation data
- Compare Top ZNF143 Proteins
-
Quality Products:
- Search GeneTex for Proteins for ZNF143
Assay Products
No data available for DME Specific Peptides for ZNF143 Gene
Domains & Families for ZNF143 Gene
Gene Families for ZNF143 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZNF143 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZNF143 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P52747- Family:
-
- Belongs to the GLI C2H2-type zinc-finger protein family.
Function for ZNF143 Gene
Molecular function for ZNF143 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8.
- GENATLAS Biochemistry:
- zinc finger protein 143,GLI-Kruppel family member,homolog of Xenopus laevis STAF transcriptional activator ortholog
Phenotypes From GWAS Catalog for ZNF143 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | 10893243 |
| GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | NAS | 19274049 |
| GO:0001077 | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | 10893243 |
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
Phenotypes for ZNF143 Gene
- MGI mutant phenotypes for ZNF143:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ZNF143:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ZNF143
-
CRISPR Products
-
OriGene CRISPR knockouts for ZNF143
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF143
- genomics-online: gRNA clones - Search results for available ZNF143 gene related products
- Applied Biological Materials CRISPR for ZNF143
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF143
- GenScript: Design CRISPR guide RNA sequences for ZNF143
miRNA for ZNF143 Gene
- miRTarBase miRNAs that target ZNF143
Targeted motifs for ZNF143 Gene
HOMER Transcription Factor Regulatory Elements motif ZNF143
- Consensus sequence: ATTTCCCAGVAKSCY Submotif: canonical Cell Type: CUTLL GEO ID: GSE29600
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF143
- Browse OriGene Inhibitory RNA Products For ZNF143
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF143
- genomics-online: shRNA clones - Search results for available ZNF143 gene related products
Clone Products
- VectorBuilder custom plasmid, inducible vectors for ZNF143
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZNF143
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF143
- genomics-online: cdna clones - Search results for available ZNF143 gene related products
- orf clones - Search results for available ZNF143 gene related products
- Applied Biological Materials Clones for ZNF143
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ZNF143
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models and Transcription Factor Targets for ZNF143 Gene
Localization for ZNF143 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZNF143 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
- Nuclear bodies (2)
- Nucleoplasm (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
Pathways & Interactions for ZNF143 Gene
Pathways by source for ZNF143 Gene
Interacting Proteins for ZNF143 Gene
Selected Interacting proteins:
P52747-ZN143_HUMAN
ENSP00000379847
for ZNF143 Gene via
UniProtKB
IID
STRING
GPS-Prot Interaction Network for ZNF143
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006357 | regulation of transcription by RNA polymerase II | TAS | 9566884 |
| GO:0006359 | regulation of transcription by RNA polymerase III | TAS | 9566884 |
| GO:0006366 | transcription by RNA polymerase II | TAS | 9009278 |
No data available for SIGNOR curated interactions for ZNF143 Gene
Transcripts for ZNF143 Gene
mRNA/cDNA for ZNF143 Gene
- (114) Selected AceView cDNA sequences:
- (6) Additional mRNA sequences :
- (12) REFSEQ mRNAs :
- (18) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000299606 2562 bps (uc057yxt.1)
- ENST00000396597 1954 bps (uc010rby.3)
- ENST00000396602 2947 bps (uc001mhr.3)
- ENST00000396604 2696 bps (uc057yxn.1)
- ENST00000412390 554 bps (uc057yxv.1)
Unigene Clusters for ZNF143 Gene
- Zinc finger protein 143:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for ZNF143
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF143
- genomics-online: gRNA clones - Search results for available ZNF143 gene related products
- Applied Biological Materials CRISPR for ZNF143
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF143
- GenScript: Design CRISPR guide RNA sequences for ZNF143
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF143
- Browse OriGene Inhibitory RNA Products For ZNF143
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF143
- genomics-online: shRNA clones - Search results for available ZNF143 gene related products
Clone Products
- VectorBuilder custom plasmid, inducible vectors for ZNF143
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZNF143
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF143
- genomics-online: cdna clones - Search results for available ZNF143 gene related products
- orf clones - Search results for available ZNF143 gene related products
- Applied Biological Materials Clones for ZNF143
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||||
| SP5: |
Expression for ZNF143 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Peripheral blood mononuclear cells (15.4), CD8 Tcells (10.6), Retina (7.6), Fetal Liver (7.3), and NK cells (7.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF143 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ZNF143 Gene:
ZNF143SOURCE GeneReport for Unigene cluster for ZNF143 Gene:
Hs.523471mRNA Expression by UniProt/SwissProt for ZNF143 Gene:
P52747-ZN143_HUMAN
Tissue specificity:
Expressed in all tissues tested, with the strongest expression in ovary.
Evidence on tissue expression from TISSUES for ZNF143 Gene
- Nervous system(4.6)
- Muscle(4.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for ZNF143
-
OriGene qPCR primer pairs for ZNF143
- genomics-online: primer clones - Search results for available ZNF143 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF143 Gene
Orthologs for ZNF143 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ZNF143 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | ZNF143 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ZNF143 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | ZNF143 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Zfp143 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Zfp143 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ZNF143 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ZNF143 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ZNF143 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | znf143 33 |
|
||
| Str.3450 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.23822 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | wee1 34 |
|
OneToMany | |
| znf143b 34 33 |
|
OneToMany | |||
| znf143a 34 |
|
OneToMany | |||
| zgc66276 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.13634 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for ZNF143 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for ZNF143 Gene
- ENSEMBL:
- Gene Tree for ZNF143 (if available)
- TreeFam:
- Gene Tree for ZNF143 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ZNF143: view image
Paralogs for ZNF143 Gene
(150) SIMAP similar genes for ZNF143 Gene using alignment to 16 proteins:
- ZN143_HUMAN
- C9J2G7_HUMAN
- C9JCG1_HUMAN
- C9JRS3_HUMAN
- C9JTC5_HUMAN
- E7EN86_HUMAN
- E7ER34_HUMAN
- E9PJF2_HUMAN
- E9PLN4_HUMAN
- E9PLS7_HUMAN
- E9PMY8_HUMAN
- E9PPB0_HUMAN
- E9PS81_HUMAN
- H7C1P6_HUMAN
- Q9H176_HUMAN
- Q9H4D4_HUMAN
- ZNF76
- HZF16
- ZNF664
- ZNF826P
- ZNF436
- ZNF78L1
- ZNF75A
- ZNF697
- ZNF627
- ZNF782
- ZSCAN2
- ZNF833P
- ZNF670
- ZNF558
- ZNF239
- ZNF180
- HZF14
- DKFZp666C237
- ZNF514
- ZNF
- ZNF844
- ZNF778
- ZNF718
- ZNF500
- ZNF391
- ZNF286A
- ZNF79
- ZFP2
- ZNF141
- ZNF101
- Nbla00121
- DKFZp686N14223
- DKFZp434J0650
- ZNF3
- ZNF491
- ZSCAN31
- ZNF883
- ZNF72
- ZNF586
- ZNF566
- ZNF55
- ZNF323
- ZNF25
- ZNF204
- HZF30
- DKFZp313M0722
- ZNF234
- ZNF154
- zf30
- kr-znf3
- ZNF829
- ZNF808
- ZNF773
- ZNF696
- ZNF684
- ZNF561
- ZNF557
- ZNF419
- ZNF146
- ZFP37
- ZNF124
- ZNF121
- PLAGL1
- HZF41
- HZF40
- HZF36
- DKFZp666M039
- ZNF383
- ZNF501
- ZNF736
- ZNF735
- ZNF660
- ZNF506
- ZNF331
- ZNF32
- ZNF22
- ZFS-5
- ZFP41
- DKFZp686M04222
- DKFZp686G16228
- DKFZp570I0164
- ZNF662
- ZNF625
- ZFS-1
- ZNF679
- ZNF485
- ZNF2
- ZNF140
- ZFP1
- DKFZp762K012
- DKFZp686D2168
- ZIC4
- ZSCAN21
- ZNF682
- ZNF578
- HZF17
- DKFZp686O1631
- DKFZp686O111
- DKFZp686H10254
- CTCFL
- ZNF585B
- ZNF620
- ZNF73
- ZNF691
- smap-7
- ZNF876P
- ZNF805
- ZNF589
- ZNF498
- ZNF275
- ZNF138
- ZNF134
- ZKSCAN1
- ZFS-6
- PLZF
- KLF1
- DKFZp686N0199
- ZNF322
- ZNFN1A2
- ZNF771
- ZNF770
- ZNF702P
- ZNF600
- ZNF547
- ZNF449
- ZFS-2
- MST154
- GLI4
- GFI1
- A-328A3.4
- ZNF80
- ZNF705A
- ZNF585A
- ZNF468
- ZNF137P
- ZFP92
- ZFP64
- GLIS3
- DKFZp434G1930
- ZNF559
- ZNF550
- ZNF410
- ZNF282
- ZNF763
- ZNF726P1
- ZNF705E
- ZFS-3
- KLF16
- GFI1B
- DKFZp547H249
Variants for ZNF143 Gene
| SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000140102 | -- | 9,526,009(+) | C/T | intron_variant | |
| rs1000157718 | -- | 9,461,468(+) | C/T | 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant | |
| rs1000180202 | -- | 9,464,466(+) | T/C | genic_upstream_transcript_variant, intron_variant | |
| rs1000204026 | -- | 9,500,459(+) | A/C | intron_variant | |
| rs1000245420 | -- | 9,506,865(+) | A/T | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv584n106 | CNV | deletion | 24896259 |
| esv24739 | CNV | loss | 19812545 |
| esv2486941 | CNV | deletion | 19546169 |
| esv2675320 | CNV | deletion | 23128226 |
| esv2744093 | CNV | deletion | 23290073 |
| esv3547301 | CNV | deletion | 23714750 |
| esv3625334 | CNV | loss | 21293372 |
| esv3625335 | CNV | loss | 21293372 |
| esv3625336 | CNV | loss | 21293372 |
| nsv1039537 | CNV | gain | 25217958 |
| nsv1055078 | CNV | gain | 25217958 |
| nsv1069561 | CNV | deletion | 25765185 |
| nsv1119859 | CNV | deletion | 24896259 |
| nsv1122583 | CNV | deletion | 24896259 |
| nsv1148850 | CNV | deletion | 26484159 |
| nsv499766 | OTHER | inversion | 21111241 |
| nsv512209 | CNV | loss | 21212237 |
| nsv553467 | CNV | loss | 21841781 |
| nsv7215 | OTHER | inversion | 18451855 |
| nsv7670 | CNV | deletion | 18451855 |
| nsv7671 | CNV | insertion | 18451855 |
| nsv957161 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
4.29% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.06;
50.59% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZNF143 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF143 Gene
Disorders for ZNF143 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| cataract 1, multiple types |
|
|
| split-hand/foot malformation 1 |
|
|
Search ZNF143 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ZNF143
No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF143 Gene
Publications for ZNF143 Gene
- CHD8 associates with human Staf and contributes to efficient U6 RNA polymerase III transcription. (PMID: 17938208) Yuan CC … Hernandez N (Molecular and cellular biology 2007) 3 4 22 58
- Molecular cloning of a cDNA encoding human SPH-binding factor, a conserved protein that binds to the enhancer-like region of the U6 small nuclear RNA gene promoter. (PMID: 9776743) Rincon JC … Kunkel GR (Nucleic acids research 1998) 3 4 22 58
- Transcriptional regulation of the human establishment of cohesion 1 homolog 2 gene. (PMID: 20116366) Nishihara M … Yanagihara I (Biochemical and biophysical research communications 2010) 3 22 58
- ZNF143 interacts with p73 and is involved in cisplatin resistance through the transcriptional regulation of DNA repair genes. (PMID: 17297437) Wakasugi T … Kohno K (Oncogene 2007) 3 22 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
Products for ZNF143 Gene
- R&D Systems Antibodies for ZNF143 (ZNF143)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for ZNF143
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ZNF143
- Search Origene for MassSpec and Protein Over-expression Lysates for ZNF143
- Origene Custom Protein Services for ZNF143
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF143
- Browse OriGene Inhibitory RNA Products For ZNF143
- OriGene qPCR primer pairs and template standards for ZNF143
- OriGene qPCR primer pairs for ZNF143
- OriGene CRISPR knockouts for ZNF143
- OriGene ORF clones in human for ZNF143
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ZNF143
- GenScript: Next-day shipping of latest version cDNA ORF clones for ZNF143 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for ZNF143
- GenScript Custom Assay Services for ZNF143
- GenScript Custom overexpressing Cell Line Services for ZNF143
- GenScript: Design CRISPR guide RNA sequences for ZNF143
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ZNF143
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for ZNF143
- Novus Biologicals proteins and lysates for ZNF143
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- VectorBuilder custom plasmid, inducible vectors for ZNF143
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ZNF143
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 24 available ZNF143 Antibodies ranked by validation data
- Compare Top ZNF143 Antibodies
- Quality Products:
- antibodies-online: Search results for available ZNF143 related products ranked by validation data
- antibodies-online: Search results for 3 available ZNF143 Proteins ranked by validation data
- Compare Top ZNF143 Proteins
- Quality Products:
- GeneTex ZNF143 Antibody for ZNF143
- Search GeneTex for Proteins for ZNF143
- Santa Cruz Biotechnology (SCBT) Antibodies for ZNF143
- Search Santa Cruz Biotechnology (SCBT) for ZNF143 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ZNF143
- Horizon Cell Lines for ZNF143
- genomics-online: cdna clones - Search results for available ZNF143 gene related products
- orf clones - Search results for available ZNF143 gene related products
- genomics-online: gRNA clones - Search results for available ZNF143 gene related products
- genomics-online: primer clones - Search results for available ZNF143 gene related products
- genomics-online: shRNA clones - Search results for available ZNF143 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF143
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF143
- GeneCopoeia miRNA 3'UTR Target clone products for ZNF143
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF143
Sources for ZNF143 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio