Aliases for ZNF143 Gene
External Ids for ZNF143 Gene
Previous GeneCards Identifiers for ZNF143 Gene
GeneCards Summary for ZNF143 Gene
ZNF143 (Zinc Finger Protein 143) is a Protein Coding gene. Diseases associated with ZNF143 include Disorders Of Intracellular Cobalamin Metabolism and Basilar Artery Insufficiency. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and RNA Polymerase III Transcription Initiation. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF76.
UniProtKB/Swiss-Prot Summary for ZNF143 Gene
Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8.