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Aliases for ZNF143 Gene
Aliases for ZNF143 Gene
External Ids for ZNF143 Gene
- HGNC: 12928
- Entrez Gene: 7702
- Ensembl: ENSG00000166478
- OMIM: 603433
- UniProtKB: P52747
Previous GeneCards Identifiers for ZNF143 Gene
- GC11P010122
- GC11P009522
- GC11P009446
- GC11P009439
- GC11P009153
Summaries for ZNF143 Gene
GeneCards Summary for ZNF143 Gene
ZNF143 (Zinc Finger Protein 143) is a Protein Coding gene. Diseases associated with ZNF143 include Disorders Of Intracellular Cobalamin Metabolism and Cataract 1, Multiple Types. Among its related pathways are RNA Polymerase III Transcription Initiation and Tat-mediated elongation of the HIV-1 transcript. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF76.
UniProtKB/Swiss-Prot Summary for ZNF143 Gene
-
Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8.
Additional gene information for ZNF143 Gene
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF143 Gene
Genomics for ZNF143 Gene
GeneHancer (GH) Regulatory Elements for ZNF143 Gene
Promoters and enhancers for ZNF143 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ZNF143 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the ZNF143 gene promoter:
-
- aMEF-2
- AML1a
- AP-1
- ATF-2
- Brachyury
- c-Jun
- HFH-1
- MEF-2A
Genomic Locations for ZNF143 Gene
Genomic Locations for ZNF143 Gene
- chr11:9,460,319-9,528,524
- (GRCh38/hg38)
- Size:
- 68,206 bases
- Orientation:
- Plus strand
- chr11:9,481,866-9,550,071
- (GRCh37/hg19)
- Size:
- 68,206 bases
- Orientation:
- Plus strand
Genomic View for ZNF143 Gene
Genes around ZNF143 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11p15.4 by HGNC
- 11p15.4 by Entrez Gene
- 11p15.4 by Ensembl
ZNF143 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZNF143 Gene
Proteins for ZNF143 Gene
-
Protein details for ZNF143 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P52747-ZN143_HUMAN
- Recommended name:
- Zinc finger protein 143
- Protein Accession:
- P52747
- A8K518
- B4DLY5
- E7ER34
- O75559
- Q8WUK9
Protein attributes for ZNF143 Gene
- Size:
- 638 amino acids
- Molecular mass:
- 68896 Da
- Quaternary structure:
-
- Interacts with CHD8.
- SequenceCaution:
-
- Sequence=AAC50266.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH20219.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAF83822.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for ZNF143 Gene
Post-translational modifications for ZNF143 Gene
Other Protein References for ZNF143 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Atlas Antibodies Anti-ZNF143 Antibody (HPA003263) and Anti-ZNF143 Antibody (HPA074818)
-
Custom Antibody ServicesOriGene Antibodies for ZNF143
- Novus Biologicals Antibodies for ZNF143
-
Abcam antibodies for ZNF143
- Invitrogen Antibodies for ZNF143 (AFLGC-ZNF143)
-
Biorbyt antibodies for ZNF143
-
Santa Cruz Biotechnology (SCBT) Antibodies for ZNF143
Protein Products
- Atlas Antibodies PrEST Antigen ZNF143 (APrEST84793) and PrEST Antigen ZNF143 (APrEST93250)
- Creative Biomart Recombinant Human ZNF143 293 Cell Lysate
-
OriGene Purified Proteins for ZNF143
- Search Origene for MassSpec and Protein Over-expression Lysates for ZNF143
- Origene Custom Protein Services for ZNF143
- antibodies-online: Show 3 available ZNF143 Proteins ranked by validation data
- Compare Top ZNF143 Proteins
-
Quality Products:
-
Abcam proteins for ZNF143
No data available for DME Specific Peptides for ZNF143 Gene
Domains & Families for ZNF143 Gene
Gene Families for ZNF143 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZNF143 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZNF143 Gene
- GenScript: Design optimal peptide antigens:
-
- ZNF143 protein (Q9H176_HUMAN)
- ZNF143 protein (Q9H4D4_HUMAN)
- Selenocysteine tRNA gene transcription-activating factor (ZN143_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P52747- Family:
-
- Belongs to the GLI C2H2-type zinc-finger protein family.
Function for ZNF143 Gene
Molecular function for ZNF143 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8.
- GENATLAS Biochemistry:
- zinc finger protein 143,GLI-Kruppel family member,homolog of Xenopus laevis STAF transcriptional activator ortholog
Phenotypes From GWAS Catalog for ZNF143 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | 10893243 |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | NAS | 19274049 |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | IDA | 10893243 |
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | IBA | 21873635 |
Phenotypes for ZNF143 Gene
- MGI mutant phenotypes for ZNF143:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ZNF143:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for ZNF143
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF143
- genomics-online: gRNA clones - Search results for available ZNF143 gene related products
- Applied Biological Materials (abm): CRISPR Clones for ZNF143 - Select products 50% OFF >
- * ZNF143 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * ZNF143 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF143
miRNA for ZNF143 Gene
- miRTarBase miRNAs that target ZNF143
Targeted motifs for ZNF143 Gene
HOMER Transcription Factor Regulatory Elements motif ZNF143
- Consensus sequence: ATTTCCCAGVAKSCY Submotif: canonical Cell Type: CUTLL GEO ID: GSE29600
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for ZNF143
- Browse OriGene Inhibitory RNA Products For ZNF143
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF143
- genomics-online: shRNA clones - Search results for available ZNF143 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ZNF143
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF143
- genomics-online: cdna clones - Search results for available ZNF143 gene related products
- orf clones - Search results for available ZNF143 gene related products
- Applied Biological Materials (abm): Clones for ZNF143 - Select products 50% OFF >
- * ZNF143 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * ZNF143 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Cell Line Products
-
Horizon Cell Lines for ZNF143
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models and Transcription Factor Targets for ZNF143 Gene
Localization for ZNF143 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZNF143 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
- Nuclear bodies (2)
- Nucleoplasm (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | 21873635 |
| GO:0005654 | nucleoplasm | TAS | -- |
Pathways & Interactions for ZNF143 Gene
Pathways by source for ZNF143 Gene
Interacting Proteins for ZNF143 Gene
GPS-Prot Interaction Network for ZNF143
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | IBA | 21873635 |
| GO:0006357 | regulation of transcription by RNA polymerase II | TAS | 9566884 |
| GO:0006359 | regulation of transcription by RNA polymerase III | TAS | 9566884 |
| GO:0006366 | transcription by RNA polymerase II | TAS | 9009278 |
| GO:0006383 | transcription by RNA polymerase III | TAS | 9009278 |
No data available for SIGNOR curated interactions for ZNF143 Gene
Drugs & Compounds for ZNF143 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|
Drug Products
- Atlas Antibodies PrEST Antigen ZNF143 (APrEST84793) and PrEST Antigen ZNF143 (APrEST93250)
- Creative Biomart Recombinant Human ZNF143 293 Cell Lysate
Transcripts for ZNF143 Gene
mRNA/cDNA for ZNF143 Gene
- (3) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (114) Selected AceView cDNA sequences:
- (18) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000299606 2562 bps (ENST00000299606.6)
- ENST00000396597 1954 bps (ENST00000396597.7)
- ENST00000396602 2900 bps (ENST00000396602.6)
- ENST00000396604 2696 bps (ENST00000396604.5)
- ENST00000412390 554 bps (ENST00000412390.6)
CRISPR Products
-
OriGene CRISPR knockouts for ZNF143
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF143
- genomics-online: gRNA clones - Search results for available ZNF143 gene related products
- Applied Biological Materials (abm): CRISPR Clones for ZNF143 - Select products 50% OFF >
- * ZNF143 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * ZNF143 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF143
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for ZNF143
- Browse OriGene Inhibitory RNA Products For ZNF143
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF143
- genomics-online: shRNA clones - Search results for available ZNF143 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ZNF143
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF143
- genomics-online: cdna clones - Search results for available ZNF143 gene related products
- orf clones - Search results for available ZNF143 gene related products
- Applied Biological Materials (abm): Clones for ZNF143 - Select products 50% OFF >
- * ZNF143 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * ZNF143 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||||
| SP5: |
Expression for ZNF143 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Peripheral blood mononuclear cells (15.4), CD8 Tcells (10.6), Retina (7.6), Fetal Liver (7.3), and NK cells (7.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF143 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ZNF143 Gene:
ZNF143SOURCE GeneReport for Unigene cluster for ZNF143 Gene:
Hs.523471mRNA Expression by UniProt/SwissProt for ZNF143 Gene:
P52747-ZN143_HUMAN
Tissue specificity:
Expressed in all tissues tested, with the strongest expression in ovary.
Evidence on tissue expression from TISSUES for ZNF143 Gene
- Nervous system(4.6)
- Muscle(4.2)
Primer Products
-
OriGene qPCR primer pairs for ZNF143
-
OriGene qPCR primer pairs and template standards for ZNF143
- genomics-online: primer clones - Search results for available ZNF143 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF143 Gene
Orthologs for ZNF143 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ZNF143 33 32 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | ZNF143 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ZNF143 33 32 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | ZNF143 33 32 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Zfp143 17 33 32 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Zfp143 32 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ZNF143 33 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ZNF143 33 32 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ZNF143 33 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | znf143 32 |
|
||
| Str.3450 32 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.23822 32 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | wee1 33 |
|
OneToMany | |
| znf143b 33 32 |
|
OneToMany | |||
| znf143a 33 |
|
OneToMany | |||
| zgc66276 32 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.13634 32 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 33 |
|
OneToMany |
- Species where no ortholog for ZNF143 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for ZNF143 Gene
- ENSEMBL:
- Gene Tree for ZNF143 (if available)
- TreeFam:
- Gene Tree for ZNF143 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ZNF143: view image
Paralogs for ZNF143 Gene
Paralogs for ZNF143 Gene
- ZNF76 5
- MTF1 5
- PRDM10 5
- ZNF148 5
- PRDM1 5
- PATZ1 5
- ZNF281 5
- ZNF276 5
- ZNF653 5
- PRDM14 5
- MAZ 5
- ZNF451 5
- VEZF1 5
- HIC1 5
- ZNF410 5
- HIC2 5
- ZBTB20 5
- ZBTB16 5
- ZBTB7C 5
- ZNF362 5
- ZNF575 5
- ZFP91-CNTF 5
- ZNF692 5
- ZFP91 5
- ZNF384 5
- PRDM6 5
- SCRT1 5
- ZBTB45 5
- ZNF296 5
- SCRT2 5
- ZBTB18 5
- ZBTB1 5
- SNAI2 5
- ZBTB42 5
- SNAI3 5
- ZBTB32 5
- SNAI1 5
- ENSG00000267477 5
(150) SIMAP similar genes for ZNF143 Gene using alignment to 16 proteins:
- ZN143_HUMAN
- C9J2G7_HUMAN
- C9JCG1_HUMAN
- C9JRS3_HUMAN
- C9JTC5_HUMAN
- E7EN86_HUMAN
- E7ER34_HUMAN
- E9PJF2_HUMAN
- E9PLN4_HUMAN
- E9PLS7_HUMAN
- E9PMY8_HUMAN
- E9PPB0_HUMAN
- E9PS81_HUMAN
- H7C1P6_HUMAN
- Q9H176_HUMAN
- Q9H4D4_HUMAN
- ZNF76
- HZF16
- ZNF664
- ZNF826P
- ZNF436
- ZNF78L1
- ZNF75A
- ZNF697
- ZNF627
- ZNF782
- ZSCAN2
- ZNF833P
- ZNF670
- ZNF558
- ZNF239
- ZNF180
- HZF14
- DKFZp666C237
- ZNF514
- ZNF
- ZNF844
- ZNF778
- ZNF718
- ZNF500
- ZNF391
- ZNF286A
- ZNF79
- ZFP2
- ZNF141
- ZNF101
- Nbla00121
- DKFZp686N14223
- DKFZp434J0650
- ZNF3
- ZNF491
- ZSCAN31
- ZNF883
- ZNF72
- ZNF586
- ZNF566
- ZNF55
- ZNF323
- ZNF25
- ZNF204
- HZF30
- DKFZp313M0722
- ZNF234
- ZNF154
- zf30
- kr-znf3
- ZNF829
- ZNF808
- ZNF773
- ZNF696
- ZNF684
- ZNF561
- ZNF557
- ZNF419
- ZNF146
- ZFP37
- ZNF124
- ZNF121
- PLAGL1
- HZF41
- HZF40
- HZF36
- DKFZp666M039
- ZNF383
- ZNF501
- ZNF736
- ZNF735
- ZNF660
- ZNF506
- ZNF331
- ZNF32
- ZNF22
- ZFS-5
- ZFP41
- DKFZp686M04222
- DKFZp686G16228
- DKFZp570I0164
- ZNF662
- ZNF625
- ZFS-1
- ZNF679
- ZNF485
- ZNF2
- ZNF140
- ZFP1
- DKFZp762K012
- DKFZp686D2168
- ZIC4
- ZSCAN21
- ZNF682
- ZNF578
- HZF17
- DKFZp686O1631
- DKFZp686O111
- DKFZp686H10254
- CTCFL
- ZNF585B
- ZNF620
- ZNF73
- ZNF691
- smap-7
- ZNF876P
- ZNF805
- ZNF589
- ZNF498
- ZNF275
- ZNF138
- ZNF134
- ZKSCAN1
- ZFS-6
- PLZF
- KLF1
- DKFZp686N0199
- ZNF322
- ZNFN1A2
- ZNF771
- ZNF770
- ZNF702P
- ZNF600
- ZNF547
- ZNF449
- ZFS-2
- MST154
- GLI4
- GFI1
- A-328A3.4
- ZNF80
- ZNF705A
- ZNF585A
- ZNF468
- ZNF137P
- ZFP92
- ZFP64
- GLIS3
- DKFZp434G1930
- ZNF559
- ZNF550
- ZNF410
- ZNF282
- ZNF763
- ZNF726P1
- ZNF705E
- ZFS-3
- KLF16
- GFI1B
- DKFZp547H249
Variants for ZNF143 Gene
| SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000140102 | -- | 9,526,009(+) | C/T | intron_variant | |
| rs1000157718 | -- | 9,461,468(+) | C/T | 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000180202 | -- | 9,464,466(+) | T/C | genic_upstream_transcript_variant, intron_variant | |
| rs1000204026 | -- | 9,500,459(+) | A/C | intron_variant | |
| rs1000245420 | -- | 9,506,865(+) | A/T | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv584n106 | CNV | deletion | 24896259 |
| esv24739 | CNV | loss | 19812545 |
| esv2486941 | CNV | deletion | 19546169 |
| esv2675320 | CNV | deletion | 23128226 |
| esv2744093 | CNV | deletion | 23290073 |
| esv3547301 | CNV | deletion | 23714750 |
| esv3625334 | CNV | loss | 21293372 |
| esv3625335 | CNV | loss | 21293372 |
| esv3625336 | CNV | loss | 21293372 |
| nsv1039537 | CNV | gain | 25217958 |
| nsv1055078 | CNV | gain | 25217958 |
| nsv1069561 | CNV | deletion | 25765185 |
| nsv1119859 | CNV | deletion | 24896259 |
| nsv1122583 | CNV | deletion | 24896259 |
| nsv1148850 | CNV | deletion | 26484159 |
| nsv499766 | OTHER | inversion | 21111241 |
| nsv512209 | CNV | loss | 21212237 |
| nsv553467 | CNV | loss | 21841781 |
| nsv7215 | OTHER | inversion | 18451855 |
| nsv7670 | CNV | deletion | 18451855 |
| nsv7671 | CNV | insertion | 18451855 |
| nsv957161 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
4.29% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.06;
50.59% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZNF143 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF143 Gene
Disorders for ZNF143 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| disorders of intracellular cobalamin metabolism |
|
|
| cataract 1, multiple types |
|
|
| split-hand/foot malformation 1 |
|
|
Search ZNF143 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ZNF143
No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF143 Gene
Publications for ZNF143 Gene
- CHD8 associates with human Staf and contributes to efficient U6 RNA polymerase III transcription. (PMID: 17938208) Yuan CC … Hernandez N (Molecular and cellular biology 2007) 3 4 23 56
- Molecular cloning of a cDNA encoding human SPH-binding factor, a conserved protein that binds to the enhancer-like region of the U6 small nuclear RNA gene promoter. (PMID: 9776743) Rincon JC … Kunkel GR (Nucleic acids research 1998) 3 4 23 56
- Transcriptional regulation of the human establishment of cohesion 1 homolog 2 gene. (PMID: 20116366) Nishihara M … Yanagihara I (Biochemical and biophysical research communications 2010) 3 23 56
- ZNF143 interacts with p73 and is involved in cisplatin resistance through the transcriptional regulation of DNA repair genes. (PMID: 17297437) Wakasugi T … Kohno K (Oncogene 2007) 3 23 56
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 56
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Sources for ZNF143 Gene
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