Aliases for ZNF143 Gene
External Ids for ZNF143 Gene
Previous GeneCards Identifiers for ZNF143 Gene
GeneCards Summary for ZNF143 Gene
ZNF143 (Zinc Finger Protein 143) is a Protein Coding gene. Diseases associated with ZNF143 include Disorders Of Intracellular Cobalamin Metabolism and Cataract 1, Multiple Types. Among its related pathways are RNA Polymerase III Transcription Initiation and Tat-mediated elongation of the HIV-1 transcript. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF76.
UniProtKB/Swiss-Prot Summary for ZNF143 Gene
Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8.