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This gene encodes a zinc finger protein containing a Kruppel-associated box (KRAB) A-box domain at its N-terminus, followed by fourteen contiguous C2H2 zinc finger domains and a degenerate zinc finger. The KRAB A-box showed weak transcriptional repressor activity in a reporter gene assay. Alternative splicing results in multiple transcript variants encoding different isoforms. ... See more...
Aliases for ZNF136 Gene
Aliases for ZNF136 Gene
External Ids for ZNF136 Gene
- HGNC: 12920
- Entrez Gene: 7695
- Ensembl: ENSG00000196646
- OMIM: 604078
- UniProtKB: P52737
Previous GeneCards Identifiers for ZNF136 Gene
- GC19P012405
- GC19P012496
- GC19P012119
- GC19P012134
- GC19P012037
- GC19P012273
- GC19P011848
Summaries for ZNF136 Gene
-
This gene encodes a zinc finger protein containing a Kruppel-associated box (KRAB) A-box domain at its N-terminus, followed by fourteen contiguous C2H2 zinc finger domains and a degenerate zinc finger. The KRAB A-box showed weak transcriptional repressor activity in a reporter gene assay. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
GeneCards Summary for ZNF136 Gene
ZNF136 (Zinc Finger Protein 136) is a Protein Coding gene. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription corepressor activity. An important paralog of this gene is ZNF627.
UniProtKB/Swiss-Prot Summary for ZNF136 Gene
-
May be involved in transcriptional regulation as a weak repressor when alone, or a potent one when fused with a heterologous protein containing a KRAB B-domain.
Additional gene information for ZNF136 Gene
- HGNC(12920)
- Entrez Gene(7695)
- Ensembl(ENSG00000196646)
- OMIM(604078)
- UniProtKB(P52737)
- Open Targets Platform(ENSG00000196646)
- Search for ZNF136 at DataMed
- Search for ZNF136 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZNF136 Gene
Genomics for ZNF136 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ZNF136 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ZNF136 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZNF136
- Top Transcription factor binding sites by QIAGEN in the ZNF136 gene promoter:
-
- GCNF
- GCNF-1
- GCNF-2
- p300
- PPAR-gamma1
- PPAR-gamma2
- RORalpha1
Genomic Locations for ZNF136 Gene
Genomic Locations for ZNF136 Gene
- chr19:12,163,047-12,189,881
- (GRCh38/hg38)
- Size:
- 26,835 bases
- Orientation:
- Plus strand
- chr19:12,273,872-12,300,064
- (GRCh37/hg19)
- Size:
- 26,193 bases
- Orientation:
- Plus strand
Genomic View for ZNF136 Gene
Genes around ZNF136 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.2 by HGNC
- 19p13.2 by Entrez Gene
- 19p13.2 by Ensembl
ZNF136 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZNF136 Gene
Proteins for ZNF136 Gene
-
Protein details for ZNF136 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P52737-ZN136_HUMAN
- Recommended name:
- Zinc finger protein 136
- Protein Accession:
- P52737
Protein attributes for ZNF136 Gene
- Size:
- 540 amino acids
- Molecular mass:
- 62784 Da
- Quaternary structure:
- No Data Available
Protein Expression for ZNF136 Gene
Post-translational modifications for ZNF136 Gene
Other Protein References for ZNF136 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-ZNF136 (aa 444-540) polyclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for ZNF136
- Novus Biologicals Antibodies for ZNF136
-
Abcam antibodies for ZNF136
- Invitrogen Antibodies for ZNF136 (AFLGC-ZNF136)
-
Santa Cruz Biotechnology (SCBT) Antibodies for ZNF136
Protein Products
-
OriGene Purified Proteins for ZNF136
- Search Origene for MassSpec and Protein Over-expression Lysates for ZNF136
- Origene Custom Protein Services for ZNF136
- antibodies-online: Show 4 available ZNF136 Proteins ranked by validation data
- Compare Top ZNF136 Proteins
-
Quality Products:
-
Abcam proteins for ZNF136
No data available for DME Specific Peptides for ZNF136 Gene
Domains & Families for ZNF136 Gene
Gene Families for ZNF136 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZNF136 Gene
- InterPro:
- Blocks:
-
- C2H2-type zinc finger signature
- KRAB box
- ProtoNet:
Suggested Antigen Peptide Sequences for ZNF136 Gene
- GenScript: Design optimal peptide antigens:
-
- Zinc finger protein 136 (ZN136_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P52737- Family:
-
- Belongs to the krueppel C2H2-type zinc-finger protein family.
Function for ZNF136 Gene
Molecular function for ZNF136 Gene
- UniProtKB/Swiss-Prot Function:
- May be involved in transcriptional regulation as a weak repressor when alone, or a potent one when fused with a heterologous protein containing a KRAB B-domain.
- GENATLAS Biochemistry:
- zinc finger protein 136 (C2H2 type,Kruppel-like,KRAB subfamily)
Phenotypes From GWAS Catalog for ZNF136 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003714 | transcription corepressor activity | TAS | 7649249 |
| GO:0005515 | protein binding | IPI | 16189514 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ZNF136 Gene
- GenomeRNAi human phenotypes for ZNF136:
-
- Increased vaccinia virus (VACV) infection
- no effect
- shRNA abundance <= 50%
- Decreased epidermal growth factor (EGF) endocytosis, decreased transferrin (TF) endocytosis
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Increased shRNA abundance (Z-score > 2)
- Decreased POU5F1-GFP protein expression
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Decreased shRNA abundance (Z-score < -2)
- Decreased OCT4 protein expression
- Decreased NANOG protein expression
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ZNF136 - Select products 50% OFF >
- * ZNF136 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ZNF136
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF136
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF136
miRNA for ZNF136 Gene
- miRTarBase miRNAs that target ZNF136
-
- hsa-miR-26b-5p (MIRT029729)
- hsa-miR-181a-5p (MIRT149977)
- hsa-miR-181b-5p (MIRT149978)
- hsa-miR-181c-5p (MIRT149979)
- hsa-miR-181d-5p (MIRT149981)
- hsa-miR-8067 (MIRT541006)
- hsa-miR-4684-5p (MIRT541007)
- hsa-miR-6508-5p (MIRT541008)
- hsa-miR-3613-3p (MIRT541009)
- hsa-miR-3675-3p (MIRT541010)
- hsa-miR-5680 (MIRT541011)
- hsa-miR-28-3p (MIRT541012)
- hsa-miR-6771-3p (MIRT541013)
- hsa-miR-1185-2-3p (MIRT552483)
- hsa-miR-1185-1-3p (MIRT552484)
- hsa-let-7f-2-3p (MIRT552485)
- hsa-miR-4789-5p (MIRT552486)
- hsa-miR-98-3p (MIRT552487)
- hsa-let-7f-1-3p (MIRT552488)
- hsa-let-7b-3p (MIRT552489)
- hsa-let-7a-3p (MIRT552490)
- hsa-miR-524-5p (MIRT552491)
- hsa-miR-520d-5p (MIRT552492)
- hsa-miR-4666a-3p (MIRT552493)
- hsa-miR-381-3p (MIRT552494)
- hsa-miR-300 (MIRT552495)
- hsa-miR-2278 (MIRT552496)
- hsa-miR-5692a (MIRT552497)
- hsa-miR-1276 (MIRT552498)
Targeted motifs for ZNF136 Gene
HOMER Transcription Factor Regulatory Elements motif ZNF136
- Consensus sequence: YTKGATAHAGTATTCTWGGTNGGCA Submotif: canonical Cell Type: HEK293 GEO ID: GSE58341
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF136
- Browse OriGene Inhibitory RNA Products For ZNF136
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF136
Clone Products
- Applied Biological Materials (abm): Clones for ZNF136 - Select products 50% OFF >
- * ZNF136 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ZNF136
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF136
Cell Line Products
-
Horizon Cell Lines for ZNF136
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models and Transcription Factor Targets for ZNF136 Gene
Localization for ZNF136 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZNF136 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 2 |
- Nucleoli (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
Pathways & Interactions for ZNF136 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Gene Expression |
.48
|
|
| 2 | Herpes simplex virus 1 infection | ||
Pathways by source for ZNF136 Gene
2 Reactome pathways for ZNF136 Gene
1 KEGG pathway for ZNF136 Gene
Interacting Proteins for ZNF136 Gene
Selected Interacting proteins:
P52737-ZN136_HUMAN
ENSP00000344162
for ZNF136 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for ZNF136
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | TAS | 7649249 |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006366 | transcription by RNA polymerase II | TAS | 7649249 |
No data available for SIGNOR curated interactions for ZNF136 Gene
Transcripts for ZNF136 Gene
mRNA/cDNA for ZNF136 Gene
- 3 REFSEQ mRNAs :
- 13 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000343979 3601 nts (view in UCSC)
- ENST00000418338 565 nts (view in UCSC)
- ENST00000425827 474 nts (view in UCSC)
- ENST00000439995 478 nts (view in UCSC)
- ENST00000464860 3579 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ZNF136 - Select products 50% OFF >
- * ZNF136 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ZNF136
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZNF136
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF136
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF136
- Browse OriGene Inhibitory RNA Products For ZNF136
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZNF136
Clone Products
- Applied Biological Materials (abm): Clones for ZNF136 - Select products 50% OFF >
- * ZNF136 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ZNF136
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZNF136
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b |
|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||
| SP2: |
Relevant External Links for ZNF136 Gene
- GeneLoc Exon Structure for
- ZNF136
Expression for ZNF136 Gene
This gene is overexpressed in Bone (58.8) and Plasma (10.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF136 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZNF136
SOURCE GeneReport for Unigene cluster for ZNF136 Gene:
Hs.479874mRNA Expression by UniProt/SwissProt for ZNF136 Gene:
P52737-ZN136_HUMAN
Tissue specificity:
Seems ubiquitous. Seen in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Evidence on tissue expression from TISSUES for ZNF136 Gene
- Lung(4.2)
- Nervous system(2.4)
Primer Products
-
OriGene qPCR primer pairs for ZNF136
-
OriGene qPCR primer pairs and template standards for ZNF136
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF136 Gene
Orthologs for ZNF136 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ZNF136 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | -- 31 |
|
ManyToMany | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG11762 32 |
|
|
|
| D19A 32 |
|
|
|||
| CG11695 32 |
|
|
- Species where no ortholog for ZNF136 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Mouse (Mus musculus)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for ZNF136 Gene
- ENSEMBL:
- Gene Tree for ZNF136 (if available)
- TreeFam:
- Gene Tree for ZNF136 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ZNF136: view image
Paralogs for ZNF136 Gene
Paralogs for ZNF136 Gene
- ZNF627 5
- ZNF625 5
- ZNF670 5
- ZKSCAN7 5
- ZNF527 5
- ZNF34 5
- ZNF214 5
- ZNF233 5
- ZNF852 5
- ZNF17 5
- ZNF530 5
- ZNF416 5
- ZNF417 5
- ZNF587 5
- ZNF776 5
- ZNF426 5
- ZNF572 5
- ZNF285 5
- ZNF287 5
- ZNF547 5
- ZNF333 5
- ZNF774 5
- ZNF407 5
- ZBTB17 5
- ZNF155 5
- ZBTB41 5
- ZNF230 5
- ZNF222 5
- ZNF697 5
- MYNN 5
- ZNF707 5
- ZNF467 5
- ZNF223 5
- ENSG00000267022 5
- GZF1 5
- ZNF768 5
- ZNF408 5
- ZNF646 5
- ZNF398 5
- ZNF777 5
- ZNF319 5
- ZNF687 5
- ZNF781 5
- ZNF592 5
- ZFP57 5
- PRDM2 5
- ZNF746 5
- ENSG00000284691 5
- ZNF644 5
- ZNF784 5
- PRDM4 5
- ZNF507 5
- WIZ 5
- ENSG00000269533 5
- ENSG00000269026 5
- ENSG00000268750 5
(512) SIMAP similar genes for ZNF136 Gene using alignment to 5 proteins:
- ZN136_HUMAN
- C9J2Q9_HUMAN
- C9JJK8_HUMAN
- C9JR58_HUMAN
- F8WES0_HUMAN
- HZF16
- ZNF627
- ZNF564
- ZNF709
- ZNF56
- ZNF818P
- ZNF78L1
- ZNF55
- ZNF625
- ZNF763
- ZNF433
- HZF36
- ZNF
- ZNF844
- ZSCAN31
- ZNF323
- ZNF397
- DKFZp666C237
- DKFZp686M04222
- DKFZp434J0650
- DKFZp313M0722
- ZNF852
- ZNF44
- ZNF799
- ZNF702P
- ZNF664
- ZNF410
- ZNF833P
- ZNF485
- ZNF391
- ZNF229
- ZFS-4
- ZNF563
- ZNF20
- ZNF124
- ZNF544
- ZNF502
- ZNF500
- ZNF41
- ZNF32
- ZNF782
- ZNF737
- ZNF69
- ZNF443
- ZNF146
- DKFZp762K012
- ZFP3
- HZF40
- ZNF700
- ZNF442
- ZNF491
- ZNF439
- ZNF878
- ZNF823
- ZNF234
- PRMD9
- smap-7
- ZNF589
- ZNF501
- zf30
- ZNF490
- ZNF358
- ZNF12
- ZFS-1
- ZFP2
- DKFZp686B16128
- ZFS-6
- ZNF558
- ZNF791
- PRDM9
- ZNF19
- ZNF72
- ZNF696
- ZSCAN22
- ZNF660
- ZNF492
- ZNF235
- HZF41
- HZF30
- ZFS-2
- ZFP41
- ZKSCAN7
- kr-znf3
- ZSCAN23
- ZNF691
- ZNF99
- ZNF883
- ZNF79
- ZNF774
- ZNF662
- ZNF626
- ZNF260
- ZNF227
- ZNF226
- ZNF14
- Nbla00121
- DKFZp686D2168
- DKFZp666M039
- DKFZp434G1930
- ZKSCAN1
- ZNF879
- ZNF45
- ZNF141
- ZNF101
- ZNF566
- ZNF726P1
- ZNF705G
- ZNF705F
- ZNF705D
- ZNF705B
- ZNF449
- ZNF282
- ZNF204
- ZNF167
- ZSCAN2
- ZNF98
- ZNF836
- ZNF835
- ZNF714
- ZNF569
- ZNF43
- ZNF35
- ZNF239
- ZFP112
- DKFZp686O111
- DKFZp686G16228
- ZKSCAN3
- ZFS-5
- ZNF441
- ZNF585B
- ZNF324
- ZNF83
- ZNF805
- ZNF675
- ZNF658B
- ZNF253
- ZNF23
- ZNF224
- ZNF112
- DKFZp686H20223
- DKFZp571N1833
- ZFP14
- ZNF570
- ZNF3
- ZSCAN30
- ZNF76
- ZNF71
- ZNF565
- ZNF283
- ZNF768
- ZNF708
- ZNF676
- ZNF668
- ZNF658
- ZNF623
- ZNF578
- ZNF573
- ZNF572
- ZNF355P
- ZNF28
- ZNF266
- ZNF208
- ZNF16
- GZF1
- DKFZp686L0787
- DKFZp572F2170
- DKFZp547L155
- ZKSCAN4
- DKFZp570I0164
- A-328A3.4
- ZNF25
- ZNF567
- ZNF331
- ZNF345
- ZFP1
- ZNF829
- ZNF721
- ZNF718
- ZNF716
- ZNF606
- ZNF431
- ZNF267
- ZNF117
- KIAA1829
- ZNF2
- ZNF861P
- ZNF682
- ZNF138
- ZNF74
- ZNF678
- ZNF550
- ZNF493
- ZNF135
- ZSCAN12
- ZNF92
- ZNF826P
- ZNF770
- ZNF705E
- ZNF705A
- ZSCAN20
- ZNF85
- ZNF814
- ZNF771
- ZNF761
- ZNF729
- ZNF695
- ZNF497
- ZNF484
- ZNF479
- ZNF415
- ZNF333
- ZNF304
- ZNF286B
- ZNF26
- ZNF250
- ZNF230
- HZF14
- DKFZp686C13142
- ZBTB17
- SNAI2
- RBAK
- HZF17
- GFI1
- ZNF254
- ZNF669
- ZNF471
- ZNF436
- ZNF420
- ZNF337
- ZNF157
- ZNF778
- ZNF726
- ZNF679
- ZNF621
- ZNF584
- ZNF57
- ZNF557
- ZNF555
- ZNF554
- ZNF486
- ZNF418
- ZNF347
- ZNF320
- ZNF30
- ZNF273
- ZNF271
- ZNF223
- ZNF214
- ZNF211
- ZNF155
- ZNF107
- ZNF100
- ZFP92
- ZNF440
- ZNF585A
- ZNF480
- ZNF876P
- ZNF785
- ZNF426
- ZNF416
- ZNF33A
- ZNF286A
- ZNF22
- ZNF175
- ZNF850
- ZNF765
- ZNF735
- ZNF73
- ZNF724P
- ZNF665
- ZNF611
- ZNF595
- ZNF470
- ZNF268
- LOC126295
- DKFZp686K03205
- ZFP82
- ZFP30
- ZNF275
- ZNF160
- ZNF540
- ZNF417
- ZNF575
- ZNF527
- ZNF287
- ZNF93
- ZNF888
- ZNF841
- ZNF81
- ZNF736
- ZNF730
- ZNF680
- ZNF643
- ZNF616
- ZNF546
- ZNF506
- ZNF354A
- ZNF334
- ZNF311
- ZNF17
- ZFP69B
- GD
- ZNF600
- ZFP28
- ZNF571
- ZNF808
- ZNF461
- ZSCAN29
- ZNFN1A2
- ZNF70
- ZNF670
- ZNF354B
- ZNF284
- ZNF213
- ZNF137P
- ZNF90
- ZNF880
- ZNF846
- ZNF813
- ZNF792
- ZNF790
- ZNF780A
- ZNF728
- ZNF720
- ZNF674
- ZNF648
- ZNF629
- ZNF620
- ZNF583
- ZNF548
- ZNF528
- ZNF354C
- ZNF343
- ZNF34
- ZNF222
- ZNF182
- ZFP62
- PLAGL1
- ZNF568
- ZNF419
- ZNF66
- ZNF460
- ZNF140
- ZNF7
- ZNF599
- ZNF514
- ZNF432
- ZNF732
- ZNF727
- ZNF624
- ZNF551
- ZNF530
- ZNF429
- ZNF404
- ZNF329
- ZNF225
- ZNF177
- ZIM3
- ZNF10
- GFI1B
- ZNF430
- ZNF587
- ZNF382
- ZNF780B
- ZNF619
- HKR1
- ZNF562
- ZNF717
- ZSCAN21
- ZNF582
- ZNF383
- ZNF845
- ZNF788
- ZNF77
- ZNF699
- ZNF677
- ZNF615
- ZNF605
- ZNF586
- ZNF519
- ZNF468
- ZNF454
- ZNF350
- ZNF251
- ZNF121
- MST154
- DKFZp686N14223
- ZIC1
- MZF1
- ZNF701
- ZNF525
- ZNF133
- ZNF594
- ZNF285A
- ZBTB47
- ZNF264
- ZNF816
- ZNF789
- ZNF766
- ZNF614
- ZNF596
- ZNF577
- ZNF529
- ZNF317
- ZNF221
- ZNF134
- ZKSCAN8
- ZFP37
- DKFZp434G1621
- ZNF33B
- ZNF630
- ZSCAN32
- ZSCAN26
- ZNF80
- ZNF498
- ZNF300
- ZNF233
- ZNF219
- ZNF613
- ZNF534
- ZNF322
- ZNF256
- ZNF181
- ZNF169
- ZNF154
- ZNF132
- MYNN
- HZF11
- ZFS-3
- HZF28
- GLI4
- ZNF561
- ZNF697
- ZNF891
- ZNF860
- ZNF775
- ZNF607
- ZNF473
- ZNF285
- ZNF184
- DKFZp686J1732
- ZNF559
- ZNF189
- ZNF84
- ZNF681
- ZNF707
- ZNF649
- ZNF581
- ZNF37A
- ZNF257
- ZNF749
- ZNF547
- ZNF543
- ZNF483
- ZNF195
- HKR3
- PLZF
- DKFZp686O1631
- ZNF776
- ZNF713
- ZNF689
- ZNF180
- ZNF840
- ZNF773
- ZNF684
- ZNF549
- ZIK1
- ZFP90
- RREB1
- ZNF672
- ZNF671
- ZNF556
- ZNF610
- ZNF324B
- ZFP69
- ZBTB41
- OSR2
- ZNF302
- ZNF510
- ZNF263
- ZNF772
- ZNF205
- TIPUH1
- RhitH
- KLF4
- ZFP64
- PRDM5
- ZNF91
- ZNF793
- ZNF786
- ZNF197
- ZNF574
- ZNF425
- ZNF248
- DKFZp564M2178
- CTCFL
- ZNF587B
- ZNF710
- ZNF764
- ZNF552
- ZNF8
- ZF6
- DKFZp686H10254
- WT1
- DKFZp547H249
- ZNF517
- ZNF667
- ZNF812
- ZNF787
- ZNF366
- REST
- DKFZp686N0199
Variants for ZNF136 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZNF136 Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs193921014 | Uncertain Significance: Malignant tumor of prostate | 12,187,261(+) | T/G | MISSENSE_VARIANT | |
| rs10425995 | - | p.Tyr107Cys |
Residual Variation Intolerance Score:
25.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.53;
11.39% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZNF136 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ZNF136
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF136 Gene
Disorders for ZNF136 Gene
Additional Disease Information for ZNF136
No disorders were found for ZNF136 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF136 Gene
Publications for ZNF136 Gene
- Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders. (PMID: 7557990) Tommerup N … Vissing H (Genomics 1995) 2 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins. (PMID: 7649249) Vissing H … Thiesen HJ (FEBS letters 1995) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations. (PMID: 31515488) Fragoza R … Yu H (Nature communications 2019) 3
ExternalLinks
Products for ZNF136 Gene
- Custom Antibody ServicesOriGene Antibodies for ZNF136
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Sources for ZNF136 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
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- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
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- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
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- (168) Rfam
- (169)