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Aliases for ZNF101 Gene

Aliases for ZNF101 Gene

  • Zinc Finger Protein 101 2 3 3 5
  • Zinc Finger Protein 101 (Y2) 2 3
  • Zinc Finger Protein HZF12 3 4
  • Zinc Finger Protein 12 3
  • HZF12 3

External Ids for ZNF101 Gene

Previous GeneCards Identifiers for ZNF101 Gene

  • GC19U990121
  • GC19P019640
  • GC19P019779
  • GC19P019341
  • GC19P019820
  • GC19P019816

Summaries for ZNF101 Gene

Entrez Gene Summary for ZNF101 Gene

  • Zinc finger proteins (ZNFs), such as ZNF101, bind nucleic acids and perform many key functions, the most important of which is regulating transcription (summary by Bellefroid et al., 1993 [PubMed 8467795]). See ZNF91 (MIM 603971) for general information on ZNFs.[supplied by OMIM, Nov 2010]

GeneCards Summary for ZNF101 Gene

ZNF101 (Zinc Finger Protein 101) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF14.

UniProtKB/Swiss-Prot for ZNF101 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF101 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF101 Gene

Genomics for ZNF101 Gene

GeneHancer (GH) Regulatory Elements for ZNF101 Gene

Promoters and enhancers for ZNF101 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J019667 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 650.7 +0.7 655 3.5 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 YY1 POLR2B E2F8 ATP13A1 ZNF101 UPF1 NDUFA13 LPAR2 MAU2 BNIP3P16 ZNF90 NR2C2AP GC19M019685
GH19J019666 Enhancer 0.4 ENCODE 650.7 -1.4 -1406 0.2 ZNF362 ZNF384 ATP13A1 ZNF101 NDUFA13 GC19M019627
GH19J019899 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 11.8 +233.0 233005 3 PKNOX1 ATF1 FOXA2 SIN3A ZNF2 YY1 ETS1 GTF3C2 TCF12 POLR2B ZNF93 ATP13A1 NR2C2AP ZNF90 ZNF66 MAU2 TMEM161A ZNF506 ENSG00000267481 ZNF101
GH19J019774 Promoter/Enhancer 1.5 Ensembl ENCODE 11.2 +108.1 108058 3.2 HDGF ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF766 ZNF207 ZNF143 LINC00663 ZNF56 ZNF506 ZNF14 ZNF101 ATP13A1 ENSG00000267693 ENSG00000267581
GH19J019860 Promoter/Enhancer 1.3 EPDnew Ensembl ENCODE 10.1 +193.1 193068 1.2 SP1 L3MBTL2 POLR2A NFYB SIN3A REST FOS MGA ZNF506 ZNF93 ATP13A1 ZNF101 BNIP3P9 ZNF253
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF101 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF101 gene promoter:
  • Roaz
  • HTF
  • TGIF
  • Ik-1
  • POU2F1
  • POU2F1a
  • AhR
  • Arnt
  • AML1a
  • CUTL1

Genomic Locations for ZNF101 Gene

Genomic Locations for ZNF101 Gene
15,357 bases
Plus strand
14,714 bases
Plus strand

Genomic View for ZNF101 Gene

Genes around ZNF101 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF101 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF101 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF101 Gene

Proteins for ZNF101 Gene

  • Protein details for ZNF101 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 101
    Protein Accession:
    Secondary Accessions:
    • C9JU83
    • Q0VDG9

    Protein attributes for ZNF101 Gene

    436 amino acids
    Molecular mass:
    50339 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF101 Gene


neXtProt entry for ZNF101 Gene

Post-translational modifications for ZNF101 Gene

  • Ubiquitination at posLast=6262
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ZNF101 Gene

Domains & Families for ZNF101 Gene

Gene Families for ZNF101 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF101 Gene

Suggested Antigen Peptide Sequences for ZNF101 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF101: view

Function for ZNF101 Gene

Molecular function for ZNF101 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF101 Gene

Gene Ontology (GO) - Molecular Function for ZNF101 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISA --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF101: view
genes like me logo Genes that share phenotypes with ZNF101: view

Animal Model Products

miRNA for ZNF101 Gene

miRTarBase miRNAs that target ZNF101

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF101 Gene

Localization for ZNF101 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF101 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF101 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF101 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF101: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF101 Gene

Pathways & Interactions for ZNF101 Gene

SuperPathways for ZNF101 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF101: view

Pathways by source for ZNF101 Gene

2 Reactome pathways for ZNF101 Gene

Gene Ontology (GO) - Biological Process for ZNF101 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZNF101: view

No data available for SIGNOR curated interactions for ZNF101 Gene

Drugs & Compounds for ZNF101 Gene

No Compound Related Data Available

Transcripts for ZNF101 Gene

Unigene Clusters for ZNF101 Gene

Zinc finger protein 101:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF101 Gene

ExUns: 1 ^ 2 ^ 3a · 3b

Relevant External Links for ZNF101 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF101 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF101 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF101 Gene

This gene is overexpressed in Whole Blood (x5.0).

Protein differential expression in normal tissues from HIPED for ZNF101 Gene

This gene is overexpressed in Breast (41.3) and Plasma (20.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF101 Gene

Protein tissue co-expression partners for ZNF101 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF101 Gene:


SOURCE GeneReport for Unigene cluster for ZNF101 Gene:


mRNA Expression by UniProt/SwissProt for ZNF101 Gene:

Tissue specificity: Expressed in a variety of adult and fetal tissues.
genes like me logo Genes that share expression patterns with ZNF101: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF101 Gene

Orthologs for ZNF101 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF101 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF101 34 33
  • 99.31 (n)
(Bos Taurus)
Mammalia -- 34
  • 50 (a)
(Mus musculus)
Mammalia Zfp961 34
  • 36 (a)
Species where no ortholog for ZNF101 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF101 Gene

Gene Tree for ZNF101 (if available)
Gene Tree for ZNF101 (if available)
Evolutionary constrained regions (ECRs) for ZNF101: view image

Paralogs for ZNF101 Gene

(528) SIMAP similar genes for ZNF101 Gene using alignment to 6 proteins:

  • ZN101_HUMAN
  • K7EN16_HUMAN
  • Q504T0_HUMAN
  • Q96F93_HUMAN Pseudogenes for ZNF101 Gene

genes like me logo Genes that share paralogs with ZNF101: view

Variants for ZNF101 Gene

Sequence variations from dbSNP and Humsavar for ZNF101 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000043525 -- 19,668,809(+) C/G 5_prime_UTR_variant, intron_variant
rs1000076409 -- 19,668,904(+) G/A 5_prime_UTR_variant, intron_variant
rs1000277645 -- 19,674,382(+) G/A intron_variant
rs1000304573 -- 19,671,914(+) TT/TTTT intron_variant
rs1000800830 -- 19,680,748(+) C/T 3_prime_UTR_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF101 Gene

Variant ID Type Subtype PubMed ID
nsv963019 CNV duplication 23825009
nsv519533 CNV gain 19592680
nsv1160593 CNV deletion 26073780
esv3643854 CNV loss 21293372
esv2659968 CNV deletion 23128226

Variation tolerance for ZNF101 Gene

Residual Variation Intolerance Score: 78.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.19; 39.60% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF101 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF101 Gene

Disorders for ZNF101 Gene

Additional Disease Information for ZNF101

No disorders were found for ZNF101 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF101 Gene

Publications for ZNF101 Gene

  1. Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. (PMID: 22359512) Demirkan A … EUROSPAN consortium (PLoS genetics 2012) 3 44 58
  2. Genetic variants influencing circulating lipid levels and risk of coronary artery disease. (PMID: 20864672) Waterworth DM … Sandhu MS (Arteriosclerosis, thrombosis, and vascular biology 2010) 3 44 58
  3. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. (PMID: 19060911) Aulchenko YS … ENGAGE Consortium (Nature genetics 2009) 3 44 58
  4. A novel Krüppel-Associated Box identified in a panel of mammalian zinc finger proteins. (PMID: 14727140) Looman C … Abrink M (Mammalian genome : official journal of the International Mammalian Genome Society 2004) 3 4 58
  5. Human chromosome 19 and related regions in mouse: conservative and lineage-specific evolution. (PMID: 11441184) Dehal P … Stubbs L (Science (New York, N.Y.) 2001) 2 3 58

Products for ZNF101 Gene

Sources for ZNF101 Gene

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