Aliases for ZMYM3 Gene
External Ids for ZMYM3 Gene
Previous HGNC Symbols for ZMYM3 Gene
Previous GeneCards Identifiers for ZMYM3 Gene
This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010]
GeneCards Summary for ZMYM3 Gene
ZMYM3 (Zinc Finger MYM-Type Containing 3) is a Protein Coding gene. Diseases associated with ZMYM3 include Loeys-Dietz Syndrome 1 and Non-Syndromic X-Linked Intellectual Disability. An important paralog of this gene is ZMYM2.
UniProtKB/Swiss-Prot Summary for ZMYM3 Gene
Plays a role in the regulation of cell morphology and cytoskeletal organization.