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Aliases for ZMYM1 Gene

Aliases for ZMYM1 Gene

  • Zinc Finger MYM-Type Containing 1 2 3 5
  • Zinc Finger, MYM Domain Containing 1 2 3
  • Zinc Finger MYM-Type Protein 1 3
  • Zinc Finger, MYM-Type 1 3
  • MYM 3

External Ids for ZMYM1 Gene

Previous GeneCards Identifiers for ZMYM1 Gene

  • GC01P034972
  • GC01P035214
  • GC01P035317
  • GC01P035526
  • GC01P033662

Summaries for ZMYM1 Gene

GeneCards Summary for ZMYM1 Gene

ZMYM1 (Zinc Finger MYM-Type Containing 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and protein dimerization activity.

Additional gene information for ZMYM1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZMYM1 Gene

Genomics for ZMYM1 Gene

GeneHancer (GH) Regulatory Elements for ZMYM1 Gene

Promoters and enhancers for ZMYM1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J035078 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 685.3 +20.1 20124 2.4 ARNT SIN3A DMAP1 YY1 POLR2B ZNF143 SP3 JUNB REST ZNF592 ZMYM1 AGO4 ZMYM6 LOC653160 SFPQ ENSG00000230163 RPL5P4 TMEM35B LOC105378647 LOC105378645
GH01J035189 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE 80.3 +131.9 131923 5 HDGF HNRNPUL1 PKNOX1 CLOCK FOXA2 SMAD1 ARID4B SIN3A DMAP1 ZNF2 SFPQ ZMYM1 LOC653160 ZMYM6 ENSG00000230163 LOC105378647 RPL5P4 AGO4 AGO3 TMEM35B
GH01J034858 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 41 -200.3 -200344 2.3 CLOCK MLX DMAP1 YY1 E2F8 ZNF143 ZNF548 ZNF263 SP3 NFYC SMIM12 GC01P034859 SFPQ LOC653160 ZMYM6 ZMYM1 ENSG00000230163 RPL5P4
GH01J035856 Enhancer 0.8 dbSUPER 109.6 +797.6 797633 2 PKNOX1 ZNF493 ZFP64 RAD21 ZNF213 ZNF202 ZNF680 ZBTB11 ZC3H11A REST GC01P035856 ZMYM1 SFPQ ZMYM6 LOC653160 ZMYM4 AGO3 RPL5P4 THRAP3 EVA1B
GH01J035640 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 37.5 +581.6 581622 2.8 PKNOX1 CLOCK SMAD1 FOXA2 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 PSMB2 SFPQ ENSG00000230163 ZMYM1 LOC653160 ZMYM6 LOC105378647 THRAP3 TFAP2E TRAPPC3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZMYM1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZMYM1 gene promoter:

Genomic Locations for ZMYM1 Gene

Genomic Locations for ZMYM1 Gene
56,074 bases
Plus strand

Genomic View for ZMYM1 Gene

Genes around ZMYM1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZMYM1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZMYM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZMYM1 Gene

Proteins for ZMYM1 Gene

  • Protein details for ZMYM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger MYM-type protein 1
    Protein Accession:
    Secondary Accessions:
    • D3DPR7
    • Q7Z3Q4

    Protein attributes for ZMYM1 Gene

    1142 amino acids
    Molecular mass:
    128717 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZMYM1 Gene

Post-translational modifications for ZMYM1 Gene

  • Ubiquitination at isoforms=106
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ZMYM1 Gene

Domains & Families for ZMYM1 Gene

Gene Families for ZMYM1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZMYM1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZMYM1: view

No data available for UniProtKB/Swiss-Prot for ZMYM1 Gene

Function for ZMYM1 Gene

Gene Ontology (GO) - Molecular Function for ZMYM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA --
GO:0003677 DNA binding IBA --
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding IEA --
GO:0046983 protein dimerization activity IEA --
genes like me logo Genes that share ontologies with ZMYM1: view
genes like me logo Genes that share phenotypes with ZMYM1: view

Animal Model Products

CRISPR Products

miRNA for ZMYM1 Gene

miRTarBase miRNAs that target ZMYM1

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZMYM1

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZMYM1 Gene

Localization for ZMYM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZMYM1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZMYM1 gene
Compartment Confidence
nucleus 4
cytoskeleton 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Microtubule organizing center (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZMYM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm IBA --
GO:0005737 cytoplasm IBA --
genes like me logo Genes that share ontologies with ZMYM1: view

Pathways & Interactions for ZMYM1 Gene

SuperPathways for ZMYM1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZMYM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription by RNA polymerase II IEA --
GO:0007010 cytoskeleton organization IBA --
GO:0022604 regulation of cell morphogenesis IBA --
genes like me logo Genes that share ontologies with ZMYM1: view

No data available for Pathways by source and SIGNOR curated interactions for ZMYM1 Gene

Drugs & Compounds for ZMYM1 Gene

No Compound Related Data Available

Transcripts for ZMYM1 Gene

Unigene Clusters for ZMYM1 Gene

Zinc finger, MYM-type 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZMYM1

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZMYM1 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b
SP1: - -
SP2: - - -
SP3: - - - - -
SP4: - - - -
SP5: - - -

Relevant External Links for ZMYM1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZMYM1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZMYM1 Gene

Protein differential expression in normal tissues from HIPED for ZMYM1 Gene

This gene is overexpressed in Fetal Liver (68.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZMYM1 Gene

Protein tissue co-expression partners for ZMYM1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZMYM1 Gene:


SOURCE GeneReport for Unigene cluster for ZMYM1 Gene:


Evidence on tissue expression from TISSUES for ZMYM1 Gene

  • Heart(4.1)
genes like me logo Genes that share expression patterns with ZMYM1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZMYM1 Gene

Orthologs for ZMYM1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ZMYM1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZMYM1 34 33
  • 99.65 (n)
(Canis familiaris)
Mammalia ZMYM1 34 33
  • 87.43 (n)
(Bos Taurus)
Mammalia ZMYM1 34 33
  • 87.02 (n)
(Rattus norvegicus)
Mammalia Zmym1 33
  • 73.41 (n)
(Mus musculus)
Mammalia Zmym1 16 34 33
  • 73.19 (n)
(Anolis carolinensis)
Reptilia -- 34
  • 24 (a)
-- 34
  • 23 (a)
-- 34
  • 23 (a)
-- 34
  • 22 (a)
-- 34
  • 22 (a)
-- 34
  • 22 (a)
-- 34
  • 21 (a)
-- 34
  • 21 (a)
-- 34
  • 20 (a)
-- 34
  • 19 (a)
(Danio rerio)
Actinopterygii LOC101886631 33
  • 45.13 (n)
ZMYM1 34
  • 19 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G06541 33
  • 46.31 (n)
(Oryza sativa)
Liliopsida Os01g0293600 33
  • 44.71 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 24 (a)
Species where no ortholog for ZMYM1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZMYM1 Gene

Gene Tree for ZMYM1 (if available)
Gene Tree for ZMYM1 (if available)
Evolutionary constrained regions (ECRs) for ZMYM1: view image

Paralogs for ZMYM1 Gene

(2) SIMAP similar genes for ZMYM1 Gene using alignment to 3 proteins:

  • Q5SW02_HUMAN Pseudogenes for ZMYM1 Gene

genes like me logo Genes that share paralogs with ZMYM1: view

No data available for Paralogs for ZMYM1 Gene

Variants for ZMYM1 Gene

Sequence variations from dbSNP and Humsavar for ZMYM1 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000032360 -- 35,064,906(+) A/G genic_upstream_transcript_variant, intron_variant
rs1000063030 -- 35,080,283(+) C/T genic_upstream_transcript_variant, intron_variant
rs1000122302 -- 35,087,301(+) T/A genic_upstream_transcript_variant, intron_variant
rs1000158729 -- 35,084,036(+) A/G genic_upstream_transcript_variant, intron_variant
rs1000175368 -- 35,105,371(+) T/C genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZMYM1 Gene

Variant ID Type Subtype PubMed ID
nsv422 CNV insertion 18451855

Variation tolerance for ZMYM1 Gene

Residual Variation Intolerance Score: 21.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.22; 69.95% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZMYM1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZMYM1 Gene

Disorders for ZMYM1 Gene

Additional Disease Information for ZMYM1

No disorders were found for ZMYM1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZMYM1 Gene

Publications for ZMYM1 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  5. Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131. (PMID: 26841866) Varier RA … Vermeulen M (The Journal of biological chemistry 2016) 3 58

Products for ZMYM1 Gene

Sources for ZMYM1 Gene

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