Aliases for ZMIZ2 Gene
ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010]
GeneCards Summary for ZMIZ2 Gene
ZMIZ2 (Zinc Finger MIZ-Type Containing 2) is a Protein Coding gene. Among its related pathways are Regulation of Androgen receptor activity. Gene Ontology (GO) annotations related to this gene include nuclear receptor transcription coactivator activity. An important paralog of this gene is ZMIZ1.
UniProtKB/Swiss-Prot Summary for ZMIZ2 Gene
Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors.