Aliases for ZKSCAN3 Gene
Aliases for ZKSCAN3 Gene
External Ids for ZKSCAN3 Gene
- HGNC: 13853
- Entrez Gene: 80317
- Ensembl: ENSG00000189298
- OMIM: 612791
- UniProtKB: Q9BRR0
Previous HGNC Symbols for ZKSCAN3 Gene
- ZNF306
- ZNF309
Previous GeneCards Identifiers for ZKSCAN3 Gene
- GC06P028426
- GC06P028317
- GC06P028124
Summaries for ZKSCAN3 Gene
GeneCards Summary for ZKSCAN3 Gene
ZKSCAN3 (Zinc Finger With KRAB And SCAN Domains 3) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and sequence-specific DNA binding. An important paralog of this gene is ZKSCAN4.
UniProtKB/Swiss-Prot Summary for ZKSCAN3 Gene
-
Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.
Additional gene information for ZKSCAN3 Gene
- Monarch Initiative
- Search for ZKSCAN3 at DataMed
- Search for ZKSCAN3 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZKSCAN3 Gene
Genomics for ZKSCAN3 Gene
GeneHancer (GH) Regulatory Elements for ZKSCAN3 Gene
Promoters and enhancers for ZKSCAN3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ZKSCAN3 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the ZKSCAN3 gene promoter:
-
- AP-2alphaA
- AP-2beta
- AP-2gamma
- c-Ets-1
- Cart-1
- GCNF
- GCNF-1
- GCNF-2
- LUN-1
Genomic Locations for ZKSCAN3 Gene
Genomic Locations for ZKSCAN3 Gene
- chr6:28,349,913-28,369,177
- (GRCh38/hg38)
- Size:
- 19,265 bases
- Orientation:
- Plus strand
- chr6:28,317,691-28,336,954
- (GRCh37/hg19)
- Size:
- 19,264 bases
- Orientation:
- Plus strand
Genomic View for ZKSCAN3 Gene
Genes around ZKSCAN3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.1 by HGNC
- 6p22.1 by Entrez Gene
- 6p22.1 by Ensembl
ZKSCAN3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZKSCAN3 Gene
Proteins for ZKSCAN3 Gene
-
Protein details for ZKSCAN3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BRR0-ZKSC3_HUMAN
- Recommended name:
- Zinc finger protein with KRAB and SCAN domains 3
- Protein Accession:
- Q9BRR0
- B2R8W2
- B3KVC0
- H7BXX1
- Q5VXH3
- Q92972
- Q9H4T3
Protein attributes for ZKSCAN3 Gene
- Size:
- 538 amino acids
- Molecular mass:
- 60641 Da
- Quaternary structure:
- No Data Available
Protein Expression for ZKSCAN3 Gene
Post-translational modifications for ZKSCAN3 Gene
Other Protein References for ZKSCAN3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ ZKSCAN3 Antibody
- Atlas Antibodies Anti-ZKSCAN3 Antibody (HPA009637) and Anti-ZKSCAN3 Antibody (HPA060116)
- GeneTex Anti-ZKSCAN3 antibody [N1C2]
- Novus Biologicals Antibodies for ZKSCAN3
-
Abcam antibodies for ZKSCAN3
- Invitrogen Antibodies for ZKSCAN3 (AFLGC-ZKSCAN3)
-
Biorbyt antibodies for ZKSCAN3
-
Santa Cruz Biotechnology (SCBT) Antibodies for ZKSCAN3
Protein Products
- Atlas Antibodies PrEST Antigen ZKSCAN3 (APrEST71036) and PrEST Antigen ZKSCAN3 (APrEST94198)
-
OriGene Purified Proteins for ZKSCAN3
- Search Origene for MassSpec and Protein Over-expression Lysates for ZKSCAN3
- Origene Custom Protein Services for ZKSCAN3
- antibodies-online: Show 5 available ZKSCAN3 Proteins ranked by validation data
- Compare Top ZKSCAN3 Proteins
-
Quality Products:
-
Abcam proteins for ZKSCAN3
No data available for DME Specific Peptides for ZKSCAN3 Gene
Domains & Families for ZKSCAN3 Gene
Gene Families for ZKSCAN3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZKSCAN3 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZKSCAN3 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ33906 fis, clone CTONG2008466, highly similar to Zinc finger protein 306 (B3KR99_HUMAN)
- Zinc finger protein 47 homolog (ZKSC3_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9BRR0- Family:
-
- Belongs to the krueppel C2H2-type zinc-finger protein family.
Function for ZKSCAN3 Gene
Molecular function for ZKSCAN3 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.
- UniProtKB/Swiss-Prot Induction:
- Overexpressed in various tumors, such as multiple myeloma, colorectal and prostate cancers (at protein level).
Phenotypes From GWAS Catalog for ZKSCAN3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | 18940803 |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISA | -- |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific | IDA | 18940803 |
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | IEA,IDA | 18940803 |
Phenotypes for ZKSCAN3 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ZKSCAN3 - Select products 50% OFF >
- * ZKSCAN3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * ZKSCAN3 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for ZKSCAN3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZKSCAN3
- genomics-online: gRNA clones - Search for available ZKSCAN3 gRNA products
- Overview of 117 available ZKSCAN3 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZKSCAN3
miRNA for ZKSCAN3 Gene
- miRTarBase miRNAs that target ZKSCAN3
-
- hsa-mir-26b-5p (MIRT029358)
- hsa-mir-6773-5p (MIRT670249)
- hsa-mir-6724-5p (MIRT670250)
- hsa-mir-7977 (MIRT670251)
- hsa-mir-3178 (MIRT670252)
- hsa-mir-6781-5p (MIRT670253)
- hsa-mir-6877-5p (MIRT670254)
- hsa-mir-24-3p (MIRT670255)
- hsa-mir-4284 (MIRT670256)
- hsa-mir-6774-5p (MIRT670257)
- hsa-mir-635 (MIRT670258)
- hsa-mir-6499-5p (MIRT670259)
- hsa-mir-338-3p (MIRT670260)
- hsa-mir-7157-5p (MIRT670261)
- hsa-mir-4310 (MIRT670262)
- hsa-mir-6513-5p (MIRT679903)
- hsa-mir-887-5p (MIRT679904)
- hsa-mir-3913-5p (MIRT679905)
- hsa-mir-3122 (MIRT679906)
- hsa-mir-450a-1-3p (MIRT679907)
- hsa-mir-6780a-5p (MIRT679908)
- hsa-mir-6779-5p (MIRT679909)
- hsa-mir-3689c (MIRT679910)
- hsa-mir-3689b-3p (MIRT679911)
- hsa-mir-3689a-3p (MIRT679912)
- hsa-mir-30b-3p (MIRT679913)
- hsa-mir-1273h-5p (MIRT679914)
- hsa-mir-6788-5p (MIRT679915)
- hsa-mir-30c-2-3p (MIRT679916)
- hsa-mir-30c-1-3p (MIRT679917)
- hsa-mir-6799-5p (MIRT679918)
- hsa-mir-6883-5p (MIRT679919)
- hsa-mir-6785-5p (MIRT679920)
- hsa-mir-4728-5p (MIRT679921)
- hsa-mir-149-3p (MIRT679922)
- hsa-mir-7106-5p (MIRT679923)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for ZKSCAN3
- Browse OriGene Inhibitory RNA Products For ZKSCAN3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZKSCAN3
- genomics-online: shRNA clones - Search for available ZKSCAN3 shRNA products
- Overview of 117 available ZKSCAN3 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for ZKSCAN3 - Select products 50% OFF >
- * ZKSCAN3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * ZKSCAN3 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for ZKSCAN3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZKSCAN3
Cell Line Products
-
Horizon Cell Lines for ZKSCAN3
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZKSCAN3 Gene
Localization for ZKSCAN3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZKSCAN3 Gene
- Nucleus. Cytoplasm. Note=Mainly localizes in the nucleus. Under starvation conditions translocates to the cytoplasm, allowing expression of target genes involved in autophagy and lysosome biogenesis/function.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 4 |
| lysosome | 1 |
- Nucleoplasm (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IEA | -- |
| GO:0005634 | nucleus | IEA,IDA | 18940803 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IDA,IEA | 23434374 |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for ZKSCAN3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Gene Expression |
.48
|
|
Pathways by source for ZKSCAN3 Gene
2 Reactome pathways for ZKSCAN3 Gene
Interacting Proteins for ZKSCAN3 Gene
Selected Interacting proteins:
Q9BRR0-ZKSC3_HUMAN
ENSP00000366465
for ZKSCAN3 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for ZKSCAN3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IDA | 18940803 |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006914 | autophagy | IEA | -- |
| GO:0007040 | lysosome organization | IMP | 23434374 |
| GO:0010507 | negative regulation of autophagy | IMP | 23434374 |
No data available for SIGNOR curated interactions for ZKSCAN3 Gene
Drugs & Compounds for ZKSCAN3 Gene
No Compound Related Data Available
Drug Products
- Atlas Antibodies PrEST Antigen ZKSCAN3 (APrEST71036) and PrEST Antigen ZKSCAN3 (APrEST94198)
Transcripts for ZKSCAN3 Gene
mRNA/cDNA for ZKSCAN3 Gene
- (3) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (33) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000252211 4687 bps (ENST00000252211.6)
- ENST00000341464 1794 bps (ENST00000341464.9)
- ENST00000377255 4799 bps (ENST00000377255.3)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ZKSCAN3 - Select products 50% OFF >
- * ZKSCAN3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * ZKSCAN3 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for ZKSCAN3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZKSCAN3
- genomics-online: gRNA clones - Search for available ZKSCAN3 gRNA products
- Overview of 117 available ZKSCAN3 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZKSCAN3
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for ZKSCAN3
- Browse OriGene Inhibitory RNA Products For ZKSCAN3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZKSCAN3
- genomics-online: shRNA clones - Search for available ZKSCAN3 shRNA products
- Overview of 117 available ZKSCAN3 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for ZKSCAN3 - Select products 50% OFF >
- * ZKSCAN3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * ZKSCAN3 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for ZKSCAN3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZKSCAN3
Expression for ZKSCAN3 Gene
This gene is overexpressed in Heart (66.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZKSCAN3 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ZKSCAN3 Gene:
ZKSCAN3SOURCE GeneReport for Unigene cluster for ZKSCAN3 Gene:
Hs.380930Primer Products
-
OriGene qPCR primer pairs for ZKSCAN3
-
OriGene qPCR primer pairs and template standards for ZKSCAN3
- genomics-online: primer clones - Search for available ZKSCAN3 Primer products
- Overview of 117 available ZKSCAN3 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZKSCAN3 Gene
Orthologs for ZKSCAN3 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ZKSCAN3 33 32 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Zkscan3 32 |
|
||
| mouse (Mus musculus) |
Mammalia | Zkscan3 17 33 32 |
|
||
| cow (Bos Taurus) |
Mammalia | -- 33 |
|
OneToMany | |
| dog (Canis familiaris) |
Mammalia | -- 33 |
|
OneToMany |
- Species where no ortholog for ZKSCAN3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Evolution for ZKSCAN3 Gene
- ENSEMBL:
- Gene Tree for ZKSCAN3 (if available)
- TreeFam:
- Gene Tree for ZKSCAN3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ZKSCAN3: view image
Paralogs for ZKSCAN3 Gene
Paralogs for ZKSCAN3 Gene
(426) SIMAP similar genes for ZKSCAN3 Gene using alignment to 1 proteins:
- ZKSC3_HUMAN
- ZKSCAN4
- ZNF883
- DKFZp686G16228
- ZNF502
- ZNF320
- HZF36
- ZNF98
- ZNF782
- ZNF772
- ZNF71
- ZNF585B
- ZNF253
- ZNF135
- ZNF134
- HZF30
- ZNF527
- ZNF93
- ZNF891
- ZNF773
- ZNF708
- ZNF675
- ZNF544
- ZNF519
- ZNF354C
- ZNF345
- ZNF300
- ZNF286B
- ZNF28
- ZNF271
- ZNF180
- ZNF117
- ZIM3
- ZFS-1
- KIAA1829
- DKFZp686B16128
- ZNF551
- ZNF510
- ZNF501
- ZNF879
- ZNF852
- ZNF845
- ZNF84
- ZNF813
- ZNF790
- ZNF79
- ZNF776
- ZNF765
- ZNF70
- ZNF660
- ZNF619
- ZNF616
- ZNF605
- ZNF595
- ZNF565
- ZNF479
- ZNF471
- ZNF470
- ZNF43
- ZNF429
- ZNF416
- ZNF254
- ZNF233
- ZNF23
- ZNF225
- ZNF211
- ZNF195
- ZNF16
- ZNF154
- ZNF132
- ZFP3
- ZFP2
- ZFP1
- DKFZp686H20223
- DKFZp571N1833
- DKFZp547L155
- ZNF286A
- ZNF33B
- ZNF234
- ZNF514
- ZNF92
- ZNF888
- ZNF85
- ZNF841
- ZNF780B
- ZNF768
- ZNF729
- ZNF718
- ZNF681
- ZNF671
- ZNF606
- ZNF600
- ZNF569
- ZNF567
- ZNF480
- ZNF454
- ZNF41
- ZNF383
- ZNF347
- ZNF34
- ZNF30
- ZNF268
- ZNF214
- ZNF208
- ZNF14
- ZFP62
- ZF6
- DKFZp686J1732
- DKFZp666M039
- DKFZp666C237
- ZNF568
- ZNF473
- ZNF99
- ZNF835
- ZNF816
- ZNF814
- ZNF792
- ZNF791
- ZNF749
- ZNF720
- ZNF701
- ZNF677
- ZNF587B
- ZNF549
- ZNF546
- ZNF484
- ZNF441
- ZNF420
- ZNF415
- ZNF358
- ZNF354A
- ZNF350
- ZNF283
- ZNF273
- ZNF267
- ZNF256
- ZNF248
- ZNF182
- ZNF141
- ZNF100
- ZIK1
- ZFP28
- HZF14
- HZF11
- DKFZp762K012
- DKFZp686K03205
- DKFZp686C13142
- DKFZp434G1930
- ZNF83
- ZNF337
- ZNF285A
- ZNF257
- zf30
- ZNF836
- ZNF81
- ZNF808
- ZNF780A
- ZNF761
- ZNF736
- ZNF732
- ZNF728
- ZNF724P
- ZNF648
- ZNF614
- ZNF599
- ZNF573
- ZNF548
- ZNF530
- ZNF528
- ZNF506
- ZNF493
- ZNF468
- ZNF45
- ZNF431
- ZNF354B
- ZNF343
- ZNF333
- ZNF285
- ZNF229
- ZNF20
- ZNF175
- ZNF146
- ZNF112
- ZFP14
- ZFP112
- HZF41
- DKFZp434G1621
- PRMD9
- ZNF461
- ZNF525
- PRDM9
- ZKSCAN8
- ZNF91
- ZNF860
- ZNF726
- ZNF695
- ZNF680
- ZNF668
- ZNF611
- ZNF607
- ZNF583
- ZNF559
- ZNF497
- ZNF418
- ZNF417
- ZNF404
- ZNF391
- ZNF334
- ZNF329
- ZNF311
- ZNF264
- ZNF230
- ZNF224
- ZNF17
- ZNF133
- Nbla00121
- GD
- DKFZp572F2170
- ZNF717
- ZNF570
- ZNF626
- ZNF578
- HKR1
- ZNF323
- ZNF878
- ZNF846
- ZNF766
- ZNF737
- ZNF709
- ZNF699
- ZNF676
- ZNF665
- ZNF627
- ZNF624
- ZNF623
- ZNF621
- ZNF587
- ZNF57
- ZNF560
- ZNF492
- ZNF486
- ZNF439
- ZNF432
- ZNF35
- ZNF32
- ZNF302
- ZNF260
- ZNF26
- ZNF25
- ZNF136
- ZNF12
- ZNF107
- ZFP90
- MST154
- LOC126295
- ZNF419
- ZNF540
- ZNF823
- ZNF805
- ZNF730
- ZNF727
- ZNF678
- ZNF674
- ZNF667
- ZNF658B
- ZNF658
- ZNF615
- ZNF585A
- ZNF571
- ZNF543
- ZNF491
- ZNF322
- ZNF275
- ZNF227
- ZNF2
- ZNF160
- ZNF140
- ZFP37
- ZFP30
- RBAK
- HZF17
- ZNF44
- ZNF566
- ZNF90
- ZNF73
- ZNF721
- ZNF69
- ZNF684
- ZNF672
- ZNF664
- ZNF643
- ZNF610
- ZNF485
- ZNF442
- ZNF436
- ZNF397
- ZNF355P
- ZNF33A
- ZNF324
- ZNF226
- ZNF19
- ZFP69B
- DKFZp686D2168
- ZSCAN2
- ZNF558
- ZNF189
- ZNF80
- ZSCAN21
- ZSCAN12
- ZNF771
- ZNF735
- ZNF586
- ZNF577
- ZNF563
- ZNF529
- ZNF37A
- ZNF324B
- ZNF266
- ZNF181
- ZNF10
- DKFZp313M0722
- ZNF778
- ZNF66
- ZNF426
- ZNF331
- ZNF589
- ZNF786
- ZNF697
- ZNF630
- ZNF620
- ZNF582
- ZNF534
- ZNF443
- ZNF316
- ZNF304
- ZNF251
- ZNF184
- ZFP69
- ZFP82
- ZNF557
- ZKSCAN1
- ZSCAN30
- ZNF840
- ZNF774
- ZNF77
- ZNF75CP
- ZNF594
- ZNF555
- ZNF235
- ZNF177
- ZNF157
- ZNF121
- DKFZp686L0787
- ZNF7
- ZNF682
- ZNF669
- ZSCAN10
- ZNF829
- ZNF714
- ZNF700
- ZNF629
- ZNF596
- ZNF490
- DKFZp686O111
- ZNF165
- ZSCAN23
- ZNF837
- ZNF75D
- ZNF716
- ZNF696
- ZNF662
- ZNF3
- ZNF287
- ZNF232
- ZNF221
- ZNF213
- ZNF169
- ZNF124
- ZKSCAN7
- DKFZp451F083
- CTCFL
- ZNF263
- ZSCAN9
- ZNF550
- ZNF500
- ZSCAN16
- ZNF561
- ZSCAN31
- ZNF880
- ZNF799
- ZNF625
- ZNF613
- ZNF572
- ZNF564
- ZNF430
- ZNF250
- ZFP92
- DKFZp686N14223
- ZNF649
- ZSCAN26
- ZSCAN22
- ZNF850
- ZNF689
- ZNF670
- ZNF554
- ZNF394
- ZKSCAN5
- TIPUH1
- GLI4
- ZNF460
- ZNF8
- ZNF547
- ZNF449
- ZNF396
- ZNF274
- ZNF24
- ZNF239
- ZNF223
- ZNF584
- ZNF517
- ZNF793
- ZSCAN20
- ZNF74
- ZNF483
- ZNF222
- ZNF174
- ZNF155
Variants for ZKSCAN3 Gene
| SNP ID | Clin | Chr 06 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000004872 | -- | 28,362,057(+) | T/C | intron_variant | |
| rs1000075038 | -- | 28,360,102(+) | C/G | 5_prime_UTR_variant, intron_variant | |
| rs1000103709 | -- | 28,354,337(+) | G/A | genic_upstream_transcript_variant, intron_variant | |
| rs1000320537 | -- | 28,368,532(+) | G/C | 3_prime_UTR_variant | |
| rs1000639054 | -- | 28,362,429(+) | G/T | intron_variant |
Residual Variation Intolerance Score:
21.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.13;
75.60% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZKSCAN3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ZKSCAN3
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZKSCAN3 Gene
Disorders for ZKSCAN3 Gene
Additional Disease Information for ZKSCAN3
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for ZKSCAN3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZKSCAN3 Gene
Publications for ZKSCAN3 Gene
- The zinc finger transcription factor ZKSCAN3 promotes prostate cancer cell migration. (PMID: 22531714) Zhang X … Yang L (The international journal of biochemistry & cell biology 2012) 2 3 4 56
- Computer sequence analysis of human highly conserved zinc finger modules. (PMID: 10520746) Petroni D … Comi P (DNA sequence : the journal of DNA sequencing and mapping 1998) 2 3 4 56
- ZKSCAN3 is a master transcriptional repressor of autophagy. (PMID: 23434374) Chauhan S … Boyd DD (Molecular cell 2013) 3 4 56
- Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. (PMID: 21946350) Soler Artigas M … Tobin MD (Nature genetics 2011) 3 43 56
- Evidence of a role for the novel zinc-finger transcription factor ZKSCAN3 in modulating Cyclin D2 expression in multiple myeloma. (PMID: 21057542) Yang L … Orlowski RZ (Oncogene 2011) 3 4 56
ExternalLinks
Products for ZKSCAN3 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ZKSCAN3
- Search Origene for MassSpec and Protein Over-expression Lysates for ZKSCAN3
- Origene Custom Protein Services for ZKSCAN3
- Origene sirna, shrna, and RNAi products in human, mouse, rat for ZKSCAN3
- Browse OriGene Inhibitory RNA Products For ZKSCAN3
- OriGene qPCR primer pairs for ZKSCAN3
- OriGene qPCR primer pairs and template standards for ZKSCAN3
- OriGene CRISPR knockouts for ZKSCAN3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ZKSCAN3
- Sino Biological Human cDNA Clone for ZKSCAN3
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for ZKSCAN3
- Novus Biologicals proteins and lysates for ZKSCAN3
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for ZKSCAN3
- Abcam proteins for ZKSCAN3
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for ZKSCAN3 (AFLGC-ZKSCAN3)
- antibodies-online: Show 8 available ZKSCAN3 Antibodies ranked by validation data
- Compare Top ZKSCAN3 Antibodies
- antibodies-online: Search results for available ZKSCAN3 related products ranked by validation data
- antibodies-online: Show 5 available ZKSCAN3 Proteins ranked by validation data
- Compare Top ZKSCAN3 Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for ZKSCAN3
- Search Santa Cruz Biotechnology (SCBT) for ZKSCAN3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ZKSCAN3
- Horizon Cell Lines for ZKSCAN3
- genomics-online: cdna clones - Search for available ZKSCAN3 CDNA products
- Overview of 117 available ZKSCAN3 gene related products
- orf clones - Search for available ZKSCAN3 ORF products
- Overview of 117 available ZKSCAN3 gene related products
- genomics-online: gRNA clones - Search for available ZKSCAN3 gRNA products
- Overview of 117 available ZKSCAN3 gene related products
- Recommended