Aliases for ZGLP1 Gene
External Ids for ZGLP1 Gene
Previous GeneCards Identifiers for ZGLP1 Gene
GeneCards Summary for ZGLP1 Gene
ZGLP1 (Zinc Finger GATA Like Protein 1) is a Protein Coding gene. Diseases associated with ZGLP1 include Hermaphroditism. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is GATA3.
UniProtKB/Swiss-Prot Summary for ZGLP1 Gene
Transcriptional regulator that plays a key role in germ cell development. Determines the oogenic fate by activating key genes for the oogenic program and meiotic prophase entry. Acts downstream of bone morphogenetic protein (BMP) by regulating expression of genes required for the oogenic programs, which are repressed by Polycomb activities in sexually uncommitted germ cells. Regulates expression of STRA8, a central downstream effector for the meiotic program. Acts independentely of retinoic acid (RA). In males, not required for germ-cell sex determination, but required to allow the spermatogonia to efficiently accomplish the meiotic prophase.