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The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggest... See more...
Aliases for ZFPM2 Gene
Aliases for ZFPM2 Gene
External Ids for ZFPM2 Gene
- HGNC: 16700
- Entrez Gene: 23414
- Ensembl: ENSG00000169946
- OMIM: 603693
- UniProtKB: Q8WW38
Previous GeneCards Identifiers for ZFPM2 Gene
- GC08P106398
- GC08P105999
- GC08P106287
- GC08P106400
- GC08P101532
- GC08P106330
Summaries for ZFPM2 Gene
-
The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq, Jul 2008]
GeneCards Summary for ZFPM2 Gene
ZFPM2 (Zinc Finger Protein, FOG Family Member 2) is a Protein Coding gene. Diseases associated with ZFPM2 include 46,Xy Sex Reversal 9 and Diaphragmatic Hernia 3. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and MicroRNAs in cancer. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription corepressor activity. An important paralog of this gene is ZFPM1.
UniProtKB/Swiss-Prot Summary for ZFPM2 Gene
-
Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY. Probably acts a corepressor of NR2F2 (By similarity).
Additional gene information for ZFPM2 Gene
- HGNC(16700)
- Entrez Gene(23414)
- Ensembl(ENSG00000169946)
- OMIM(603693)
- UniProtKB(Q8WW38)
- Open Targets Platform(ENSG00000169946)
- Monarch Initiative
- Search for ZFPM2 at DataMed
- Search for ZFPM2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZFPM2 Gene
Genomics for ZFPM2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ZFPM2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ZFPM2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZFPM2
- Top Transcription factor binding sites by QIAGEN in the ZFPM2 gene promoter:
-
- Chx10
- ER-alpha
- GATA-1
- NF-1
- p300
- POU3F2
- POU3F2 (N-Oct-5a)
- POU3F2 (N-Oct-5b)
Genomic Locations for ZFPM2 Gene
Genomic Locations for ZFPM2 Gene
- chr8:104,590,733-105,804,539
- (GRCh38/hg38)
- Size:
- 1,213,807 bases
- Orientation:
- Plus strand
- chr8:106,330,920-106,816,767
- (GRCh37/hg19)
- Size:
- 485,848 bases
- Orientation:
- Plus strand
Genomic View for ZFPM2 Gene
Genes around ZFPM2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8q23 by HGNC
- 8q23.1 by Entrez Gene
- 8q22.3 by Ensembl
ZFPM2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZFPM2 Gene
Proteins for ZFPM2 Gene
-
Protein details for ZFPM2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8WW38-FOG2_HUMAN
- Recommended name:
- Zinc finger protein ZFPM2
- Protein Accession:
- Q8WW38
- Q32MA6
- Q9NPL7
- Q9NPS4
- Q9UNI5
Protein attributes for ZFPM2 Gene
- Size:
- 1151 amino acids
- Molecular mass:
- 128159 Da
- Quaternary structure:
-
- Interacts with the N-terminal zinc-finger of GATA4, GATA5 and probably GATA6. Interacts with retinoid nuclear receptor RXRA when ligand bound (By similarity). Interacts with corepressor CTBP2; this interaction is however not essential for corepressor activity. Able to bind GATA1 in vitro. Interacts with NR2F2 and NR2F6 (By similarity). Interacts with ATOH8; mediates indirect interaction with GATA4 (By similarity).
- Miscellaneous:
-
- [Isoform 2]: Sequence incomplete.
Protein Expression for ZFPM2 Gene
Post-translational modifications for ZFPM2 Gene
- Sumoylation reduces transcriptional repression activity.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for ZFPM2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ FOG2 Antibody
-
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-
Abcam antibodies for ZFPM2
- Invitrogen Antibodies for ZFPM2 (AFLGC-ZFPM2)
-
Biorbyt antibodies for ZFPM2
-
Santa Cruz Biotechnology (SCBT) Antibodies for ZFPM2
Protein Products
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- Novus Biologicals proteins for ZFPM2
No data available for DME Specific Peptides for ZFPM2 Gene
Domains & Families for ZFPM2 Gene
Gene Families for ZFPM2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZFPM2 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZFPM2 Gene
- GenScript: Design optimal peptide antigens:
-
- Zinc finger protein multitype 2 (FOG2_HUMAN)
- Zinc finger protein, multitype 2 (Q32MA5_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8WW38UniProtKB/Swiss-Prot:
FOG2_HUMAN :- The CCHC FOG-type zinc fingers 1, 2, 3 and 5 directly bind to GATA-type zinc fingers. The Tyr residue adjacent to the last Cys of the CCHC FOG-type zinc finger is essential for the interaction with GATA-type zinc fingers (By similarity).
- Belongs to the FOG (Friend of GATA) family.
- Domain:
-
- The CCHC FOG-type zinc fingers 1, 2, 3 and 5 directly bind to GATA-type zinc fingers. The Tyr residue adjacent to the last Cys of the CCHC FOG-type zinc finger is essential for the interaction with GATA-type zinc fingers (By similarity).
- Family:
-
- Belongs to the FOG (Friend of GATA) family.
Function for ZFPM2 Gene
Molecular function for ZFPM2 Gene
- UniProtKB/Swiss-Prot Function:
- Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY. Probably acts a corepressor of NR2F2 (By similarity).
Phenotypes From GWAS Catalog for ZFPM2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISA | -- |
| GO:0001085 | RNA polymerase II transcription factor binding | IEA,IBA | 21873635 |
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003713 | transcription coactivator activity | NAS | 10438528 |
Phenotypes for ZFPM2 Gene
- MGI mutant phenotypes for ZFPM2:
-
inferred from 7 alleles
- respiratory system phenotype
- normal phenotype
- cardiovascular system phenotype
- cellular phenotype
- mortality/aging
- muscle phenotype
- homeostasis/metabolism phenotype
- liver/biliary system phenotype
- endocrine/exocrine gland phenotype
- reproductive system phenotype
- integument phenotype
- no phenotypic analysis
- GenomeRNAi human phenotypes for ZFPM2:
Animal Models for ZFPM2 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ZFPM2 - Select products 50% OFF >
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-
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miRNA for ZFPM2 Gene
- miRTarBase miRNAs that target ZFPM2
-
- mmu-miR-130a-3p (MIRT003840)
- hsa-miR-141-3p (MIRT004621)
- hsa-miR-200a-3p (MIRT004622)
- hsa-miR-200b-3p (MIRT004623)
- hsa-miR-200c-3p (MIRT004624)
- hsa-miR-429 (MIRT004625)
- hsa-miR-26b-5p (MIRT028872)
- mmu-miR-17-5p (MIRT053654)
- mmu-miR-20a-5p (MIRT053705)
- mmu-miR-19a-3p (MIRT053708)
- mmu-miR-19b-3p (MIRT053808)
- mmu-miR-92a-3p (MIRT053813)
- mmu-miR-200c-3p (MIRT438582)
- mmu-miR-200b-3p (MIRT438583)
- hsa-miR-184 (MIRT732745)
miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for ZFPM2 - Select products 50% OFF >
- * ZFPM2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
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- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZFPM2
Cell Line Products
-
Horizon Cell Lines for ZFPM2
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for ZFPM2 Gene
Localization for ZFPM2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZFPM2 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 2 |
| cytoskeleton | 2 |
| cytosol | 2 |
| plasma membrane | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000790 | nuclear chromatin | ISA | -- |
| GO:0005634 | nucleus | IBA | 21873635 |
| GO:0005654 | nucleoplasm | IDA,TAS | -- |
| GO:0005737 | cytoplasm | IEA | -- |
Pathways & Interactions for ZFPM2 Gene
Pathways by source for ZFPM2 Gene
2 Reactome pathways for ZFPM2 Gene
1 KEGG pathway for ZFPM2 Gene
Interacting Proteins for ZFPM2 Gene
Selected Interacting proteins:
Q8WW38-FOG2_HUMAN
ENSP00000384179
for ZFPM2 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for ZFPM2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IEA,IBA | 21873635 |
| GO:0001570 | vasculogenesis | IEA | -- |
| GO:0001701 | in utero embryonic development | IEA | -- |
| GO:0003148 | outflow tract septum morphogenesis | IMP | 20807224 |
| GO:0003221 | right ventricular cardiac muscle tissue morphogenesis | IMP | 20807224 |
Transcripts for ZFPM2 Gene
mRNA/cDNA for ZFPM2 Gene
- 3 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000407775 4961 nts (view in UCSC)
- ENST00000511341 1582 nts (view in UCSC)
- ENST00000517361 3300 nts (view in UCSC)
- ENST00000518180 596 nts (view in UCSC)
- ENST00000520027 594 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ZFPM2 - Select products 50% OFF >
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- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
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-
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miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for ZFPM2 - Select products 50% OFF >
- * ZFPM2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZFPM2
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||
| SP2: |
Relevant External Links for ZFPM2 Gene
- GeneLoc Exon Structure for
- ZFPM2
Expression for ZFPM2 Gene
mRNA differential expression in normal tissues according to GTEx for ZFPM2 Gene
This gene is overexpressed in Brain - Cerebellar Hemisphere (x6.5) and Brain - Cerebellum (x4.7).
This gene is overexpressed in Fetal testis (55.7) and Adipocyte (13.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZFPM2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZFPM2
SOURCE GeneReport for Unigene cluster for ZFPM2 Gene:
Hs.431009mRNA Expression by UniProt/SwissProt for ZFPM2 Gene:
Q8WW38-FOG2_HUMAN
Tissue specificity:
Widely expressed at low level.
Evidence on tissue expression from TISSUES for ZFPM2 Gene
- Nervous system(2.7)
- Heart(2.7)
- Muscle(2.5)
Phenotype-based relationships between genes and organs from Gene ORGANizer for ZFPM2 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- endocrine
- integumentary
- nervous
- reproductive
- respiratory
- skeletal muscle
- skeleton
- urinary
Regions:
Head and neck:
- brain
- ear
- eye
- eyelid
- face
- forehead
- head
- lip
- nose
- outer ear
- pituitary gland
- skull
Thorax:
- breast
- clavicle
- diaphragm
- heart
- heart valve
- lung
Abdomen:
- intestine
- large intestine
- liver
- small intestine
- stomach
Pelvis:
- fallopian tube
- ovary
- pelvis
- penis
- prostate
- testicle
- urethra
- uterus
- vagina
- vas deferens
- vulva
Limb:
- arm
- digit
- femur
- fibula
- finger
- foot
- forearm
- hand
- humerus
- lower limb
- radius
- shin
- thigh
- tibia
- toe
- ulna
- upper limb
General:
- hair
- skin
Primer Products
-
OriGene qPCR primer pairs for ZFPM2
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for ZFPM2 Gene
Orthologs for ZFPM2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ZFPM2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | ZFPM2 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | ZFPM2 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | ZFPM2 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Zfpm2 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Zfpm2 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | ZFPM2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | ZFPM2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | ZFPM2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | zfpm2 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | zfpm2a 30 31 |
|
OneToMany | |
| zfpm2b 31 |
|
OneToMany |
- Species where no ortholog for ZFPM2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for ZFPM2 Gene
- ENSEMBL:
- Gene Tree for ZFPM2 (if available)
- TreeFam:
- Gene Tree for ZFPM2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ZFPM2: view image
Paralogs for ZFPM2 Gene
Variants for ZFPM2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZFPM2 Gene
| SNP ID | Clinical significance and condition | Chr 08 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 638874 | Uncertain Significance: 46,XY sex reversal 9 | 105,803,051(+) | G/A | MISSENSE_VARIANT | |
| 644327 | Uncertain Significance: 46,XY sex reversal 9 | 105,801,971(+) | C/T | MISSENSE_VARIANT | |
| 644422 | Uncertain Significance: 46,XY sex reversal 9 | 105,801,356(+) | A/T | MISSENSE_VARIANT | |
| 647578 | Uncertain Significance: 46,XY sex reversal 9 | 105,802,382(+) | A/G | MISSENSE_VARIANT | |
| 648901 | Uncertain Significance: 46,XY sex reversal 9 | 105,802,288(+) | C/T | MISSENSE_VARIANT |
Residual Variation Intolerance Score:
46.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.02;
84.21% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ZFPM2 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZFPM2 Gene
Disorders for ZFPM2 Gene
(25) MalaCards diseases for ZFPM2 Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| 46,xy sex reversal 9 |
|
|
| diaphragmatic hernia 3 |
|
|
| double outlet right ventricle |
|
|
| tetralogy of fallot |
|
|
| conotruncal heart malformations |
|
Search ZFPM2 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
FOG2_HUMAN- Tetralogy of Fallot (TOF) [MIM:187500]: A congenital heart anomaly which consists of pulmonary stenosis, ventricular septal defect, dextroposition of the aorta (aorta is on the right side instead of the left) and hypertrophy of the right ventricle. In this condition, blood from both ventricles (oxygen-rich and oxygen-poor) is pumped into the body often causing cyanosis. {ECO:0000269 PubMed:14517948, ECO:0000269 PubMed:20807224}. Note=The disease may be caused by mutations affecting the gene represented in this entry.
- Diaphragmatic hernia 3 (DIH3) [MIM:610187]: Form of congenital diaphragmatic hernia (CDH). CDH refers to a group of congenital defects in the structural integrity of the diaphragm associated with often lethal pulmonary hypoplasia and pulmonary hypertension. {ECO:0000269 PubMed:16103912}. Note=The disease is caused by mutations affecting the gene represented in this entry.
- 46,XY sex reversal 9 (SRXY9) [MIM:616067]: A disorder of sex development. Affected individuals have a 46,XY karyotype but present as phenotypically normal females or have ambiguous external genitalia. {ECO:0000269 PubMed:24549039}. Note=The disease is caused by mutations affecting the gene represented in this entry.
- Conotruncal heart malformations (CTHM) [MIM:217095]: A group of congenital heart defects involving the outflow tracts. Examples include truncus arteriosus communis, double-outlet right ventricle and transposition of great arteries. Truncus arteriosus communis is characterized by a single outflow tract instead of a separate aorta and pulmonary artery. In transposition of the great arteries, the aorta arises from the right ventricle and the pulmonary artery from the left ventricle. In double outlet of the right ventricle, both the pulmonary artery and aorta arise from the right ventricle. {ECO:0000269 PubMed:20807224}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for ZFPM2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for Genatlas for ZFPM2 Gene
Publications for ZFPM2 Gene
- hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation. (PMID: 10438528) Holmes M … Chong B (The Journal of biological chemistry 1999) 2 3 4
- Mutations in the FOG2/ZFPM2 gene are associated with anomalies of human testis determination. (PMID: 24549039) Bashamboo A … McElreavey K (Human molecular genetics 2014) 3 4
- New mutations in ZFPM2/FOG2 gene in tetralogy of Fallot and double outlet right ventricle. (PMID: 20807224) De Luca A … Dallapiccola B (Clinical genetics 2011) 3 4
- New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C … Soranzo N (Nature 2011) 3 41
- Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels. (PMID: 21757650) Debette S … Seshadri S (Circulation research 2011) 3 41
ExternalLinks
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- Invitrogen Antibodies for ZFPM2 (AFLGC-ZFPM2)
- VectorBuilder Custom and pre-made DNA vectors for ZFPM2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for ZFPM2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for ZFPM2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for ZFPM2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for ZFPM2
- antibodies-online: Show 12 available ZFPM2 Antibodies ranked by validation data
- Compare Top ZFPM2 Antibodies
- antibodies-online: Search results for available ZFPM2 related products ranked by validation data
- antibodies-online: Search results for available ZFPM2 related products ranked by validation data
- Santa Cruz Biotechnology (SCBT) Antibodies for ZFPM2
- Search Santa Cruz Biotechnology (SCBT) for ZFPM2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ZFPM2
- Horizon Cell Lines for ZFPM2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ZFPM2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ZFPM2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for ZFPM2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZFPM2
- Biorbyt antibodies for ZFPM2
Sources for ZFPM2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB