Aliases for ZFP82 Gene

Aliases for ZFP82 Gene

  • ZFP82 Zinc Finger Protein 2 3 5
  • Zinc Finger Protein 545 2 3 4
  • Zinc Finger Protein 82 Homolog 3 4
  • ZNF545 3 4
  • Zinc Finger Protein 82 Homolog (Mouse) 2
  • Zinc Finger Protein 85 3
  • Zinc Finger Protein 82 2
  • KIAA1948 4
  • Zfp-82 4

External Ids for ZFP82 Gene

Previous HGNC Symbols for ZFP82 Gene

  • ZNF545

Previous GeneCards Identifiers for ZFP82 Gene

  • GC19M041577
  • GC19M036874
  • GC19M036882
  • GC19M033351
  • GC19M036417
  • GC19M036698
  • GC19M039002
  • GC19M039143
  • GC19M039204
  • GC19M036880
  • GC19M036901
  • GC19M037414
  • GC19M037743
  • GC19M038041
  • GC19M038336
  • GC19M038631
  • GC19M038872

Summaries for ZFP82 Gene

GeneCards Summary for ZFP82 Gene

ZFP82 (ZFP82 Zinc Finger Protein) is a Protein Coding gene. Among its related pathways are Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZFP30.

UniProtKB/Swiss-Prot Summary for ZFP82 Gene

Additional gene information for ZFP82 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ZFP82 Gene

Genomics for ZFP82 Gene

GeneHancer (GH) Regulatory Elements for ZFP82 Gene

Promoters and enhancers for ZFP82 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ZFP82 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ZFP82

Top Transcription factor binding sites by QIAGEN in the ZFP82 gene promoter:
  • Arnt
  • CREB
  • deltaCREB
  • Elk-1
  • LCR-F1
  • Pax-3
  • Pax-5
  • SEF-1 (1)
  • Tal-1beta

Genomic Locations for ZFP82 Gene

Genomic Locations for ZFP82 Gene
chr19:36,383,120-36,418,658
(GRCh38/hg38)
Size:
35,539 bases
Orientation:
Minus strand
chr19:36,874,022-36,909,558
(GRCh37/hg19)
Size:
35,537 bases
Orientation:
Minus strand

Genomic View for ZFP82 Gene

Genes around ZFP82 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZFP82 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZFP82 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZFP82 Gene

Proteins for ZFP82 Gene

  • Protein details for ZFP82 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N141-ZFP82_HUMAN
    Recommended name:
    Zinc finger protein 82 homolog
    Protein Accession:
    Q8N141
    Secondary Accessions:
    • Q8NC63
    • Q8TF53

    Protein attributes for ZFP82 Gene

    Size:
    532 amino acids
    Molecular mass:
    62578 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB85534.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}; Sequence=BAB85534.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};

neXtProt entry for ZFP82 Gene

Post-translational modifications for ZFP82 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZFP82 Gene

No data available for DME Specific Peptides for ZFP82 Gene

Domains & Families for ZFP82 Gene

Gene Families for ZFP82 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZFP82 Gene

Blocks:
  • KRAB box
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZFP82 Gene

GenScript: Design optimal peptide antigens:
  • Zinc finger protein 85 (D3Y299_HUMAN)
  • Zinc finger protein 545 (ZFP82_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8N141

UniProtKB/Swiss-Prot:

ZFP82_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZFP82: view

Function for ZFP82 Gene

Molecular function for ZFP82 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZFP82 Gene

Gene Ontology (GO) - Molecular Function for ZFP82 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZFP82: view
genes like me logo Genes that share phenotypes with ZFP82: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZFP82

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZFP82 Gene

Localization for ZFP82 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZFP82 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZFP82 gene
Compartment Confidence
nucleus 4
cytosol 2
plasma membrane 1
cytoskeleton 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nuclear membrane (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZFP82 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZFP82: view

Pathways & Interactions for ZFP82 Gene

PathCards logo

SuperPathways for ZFP82 Gene

genes like me logo Genes that share pathways with ZFP82: view

Pathways by source for ZFP82 Gene

1 KEGG pathway for ZFP82 Gene

Gene Ontology (GO) - Biological Process for ZFP82 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZFP82: view

No data available for SIGNOR curated interactions for ZFP82 Gene

Drugs & Compounds for ZFP82 Gene

No Compound Related Data Available

Transcripts for ZFP82 Gene

mRNA/cDNA for ZFP82 Gene

4 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ZFP82

Alternative Splicing Database (ASD) splice patterns (SP) for ZFP82 Gene

No ASD Table

Relevant External Links for ZFP82 Gene

GeneLoc Exon Structure for
ZFP82

Expression for ZFP82 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZFP82 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ZFP82

SOURCE GeneReport for Unigene cluster for ZFP82 Gene:

Hs.558734

Evidence on tissue expression from TISSUES for ZFP82 Gene

  • Nervous system(4.3)
  • Eye(4)
genes like me logo Genes that share expression patterns with ZFP82: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZFP82 Gene

Orthologs for ZFP82 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZFP82 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZFP82 31 30
  • 99.56 (n)
OneToOne
cow
(Bos Taurus)
Mammalia ZFP82 30
  • 91.54 (n)
dog
(Canis familiaris)
Mammalia ZFP82 31 30
  • 91.22 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp82 17 31 30
  • 82.33 (n)
rat
(Rattus norvegicus)
Mammalia LOC100910231 30
  • 80.42 (n)
Species where no ortholog for ZFP82 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZFP82 Gene

ENSEMBL:
Gene Tree for ZFP82 (if available)
TreeFam:
Gene Tree for ZFP82 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ZFP82: view image

Paralogs for ZFP82 Gene

Paralogs for ZFP82 Gene

(502) SIMAP similar genes for ZFP82 Gene using alignment to 4 proteins:

  • ZFP82_HUMAN
  • D3Y299_HUMAN
  • F5H4L8_HUMAN
  • K7ERD5_HUMAN
genes like me logo Genes that share paralogs with ZFP82: view

Variants for ZFP82 Gene

Additional dbSNP identifiers (rs#s) for ZFP82 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZFP82 Gene

Variant ID Type Subtype PubMed ID
esv3644256 CNV gain 21293372
nsv1066026 CNV gain 25217958
nsv1067101 CNV gain 25217958
nsv1114003 CNV deletion 24896259
nsv833816 CNV gain 17160897

Variation tolerance for ZFP82 Gene

Residual Variation Intolerance Score: 20.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.61; 13.10% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZFP82 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZFP82

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ZFP82 Gene

Disorders for ZFP82 Gene

Additional Disease Information for ZFP82

No disorders were found for ZFP82 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZFP82 Gene

Publications for ZFP82 Gene

  1. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PMID: 11853319) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2001) 2 3 4 54
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  4. The role of MIR-186 and ZNF545 in inhibiting the proliferation of multiple myeloma cells. (PMID: 31165610) Deng S … Zeng YQ (Journal of biological regulators and homeostatic agents 2019) 3 54
  5. The 19q13 KRAB Zinc-finger protein ZFP82 suppresses the growth and invasion of esophageal carcinoma cells through inhibiting NF-κB transcription and inducing apoptosis. (PMID: 30211622) Ye L … Ren G (Epigenomics 2019) 3 54

Products for ZFP82 Gene

Sources for ZFP82 Gene